{"id":"https://openalex.org/W1971199114","doi":"https://doi.org/10.1038/bjc.2014.175","title":"Vitamin D intake, blood 25(OH)D levels, and breast cancer risk or mortality: a meta-analysis","display_name":"Vitamin D intake, blood 25(OH)D levels, and breast cancer risk or mortality: a meta-analysis","publication_year":2014,"publication_date":"2014-04-08","ids":{"openalex":"https://openalex.org/W1971199114","doi":"https://doi.org/10.1038/bjc.2014.175","mag":"1971199114","pmid":"https://pubmed.ncbi.nlm.nih.gov/24714744","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/4037823"},"language":"en","primary_location":{"id":"doi:10.1038/bjc.2014.175","doi":"https://doi.org/10.1038/bjc.2014.175","is_oa":true,"landing_page_url":"https://doi.org/10.1038/bjc.2014.175","pdf_url":"https://www.nature.com/articles/bjc2014175.pdf","source":{"id":"https://openalex.org/S62966998","display_name":"British Journal of Cancer","issn_l":"0007-0920","issn":["0007-0920","1532-1827"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319965","host_organization_name":"Springer Nature","host_organization_lineage":["https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Nature"],"type":"journal"},"license":"cc-by-nc-sa","license_id":"https://openalex.org/licenses/cc-by-nc-sa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"British Journal of Cancer","raw_type":"journal-article"},"volume":null,"type":"review","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://www.nature.com/articles/bjc2014175.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5110558208","display_name":"Youn-Jung Kim","orcid":"https://orcid.org/0009-0008-7033-1776","observed_orcids":["https://orcid.org/0009-0008-7033-1776"]},"institutions":[{"id":"https://openalex.org/I35928602","display_name":"Kyung Hee University","ror":"https://ror.org/01zqcg218","country_code":"KR","type":"education","lineage":["https://openalex.org/I35928602"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Y Kim","raw_affiliation_strings":["Department of Food and Nutrition, Kyung Hee University, 26 Kyunghee-daero, Dongdaemun-gu, Seoul, South Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Food and Nutrition, Kyung Hee University, 26 Kyunghee-daero, Dongdaemun-gu, Seoul, South Korea","institution_ids":["https://openalex.org/I35928602"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5018055906","display_name":"Youjin Je","orcid":"https://orcid.org/0000-0002-2099-4204","observed_orcids":["https://orcid.org/0000-0002-2099-4204","https://orcid.org/0000-0001-8714-2690"]},"institutions":[{"id":"https://openalex.org/I35928602","display_name":"Kyung Hee University","ror":"https://ror.org/01zqcg218","country_code":"KR","type":"education","lineage":["https://openalex.org/I35928602"]}],"countries":["KR"],"is_corresponding":true,"raw_author_name":"Y Je","raw_affiliation_strings":["Department of Food and Nutrition, Kyung Hee University, 26 Kyunghee-daero, Dongdaemun-gu, Seoul, South Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Food and Nutrition, Kyung Hee University, 26 Kyunghee-daero, Dongdaemun-gu, Seoul, South Korea","institution_ids":["https://openalex.org/I35928602"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5018055906"],"corresponding_institution_ids":["https://openalex.org/I35928602"],"apc_list":{"value":5190,"currency":"USD","value_usd":5190},"apc_paid":{"value":5190,"currency":"USD","value_usd":5190},"fwci":2.6084,"has_fulltext":true,"cited_by_count":195,"citation_normalized_percentile":{"value":0.9249409,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":89,"max":100},"biblio":{"volume":"110","issue":"11","first_page":"2772","last_page":"2784"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10277","display_name":"Vitamin D Research Studies","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2734","display_name":"Pathology and Forensic Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10277","display_name":"Vitamin D Research Studies","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2734","display_name":"Pathology and Forensic Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10866","display_name":"Nutritional Studies and Diet","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12103","display_name":"Cancer Risks and Factors","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/vitamin-d","display_name":"vitamin D","score":0.953000009059906},{"id":"https://openalex.org/keywords/25-hydroxyvitamin-d","display_name":"25-hydroxyvitamin D","score":0.9190000295639038},{"id":"https://openalex.org/keywords/breast-cancer-risk","display_name":"breast cancer risk","score":0.7929999828338623},{"id":"https://openalex.org/keywords/breast-cancer-mortality","display_name":"breast cancer mortality","score":0.9980000257492065},{"id":"https://openalex.org/keywords/vitamin-d-intake","display_name":"vitamin D intake","score":0.8859999775886536},{"id":"https://openalex.org/keywords/vitamin-d-status","display_name":"vitamin D status","score":0.7070000171661377},{"id":"https://openalex.org/keywords/cancer-survival","display_name":"cancer survival","score":0.5809999704360962},{"id":"https://openalex.org/keywords/anti-carcinogenic-effects","display_name":"anti-carcinogenic effects","score":0.7820000052452087}],"concepts":[{"id":"https://openalex.org/C530470458","wikidata":"https://www.wikidata.org/wiki/Q128581","display_name":"Breast cancer","level":3,"score":0.8690613508224487},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8655902147293091},{"id":"https://openalex.org/C82789193","wikidata":"https://www.wikidata.org/wiki/Q2142611","display_name":"Relative risk","level":3,"score":0.6489197015762329},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.645685613155365},{"id":"https://openalex.org/C124490489","wikidata":"https://www.wikidata.org/wiki/Q7936963","display_name":"Vitamin D and neurology","level":2,"score":0.5781586170196533},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.5044301748275757},{"id":"https://openalex.org/C61511704","wikidata":"https://www.wikidata.org/wiki/Q1671857","display_name":"Incidence (geometry)","level":2,"score":0.4905621409416199},{"id":"https://openalex.org/C188816634","wikidata":"https://www.wikidata.org/wiki/Q2113324","display_name":"Prospective cohort study","level":2,"score":0.48651665449142456},{"id":"https://openalex.org/C201903717","wikidata":"https://www.wikidata.org/wiki/Q1778788","display_name":"Cohort study","level":2,"score":0.48549559712409973},{"id":"https://openalex.org/C143998085","wikidata":"https://www.wikidata.org/wiki/Q162555","display_name":"Oncology","level":1,"score":0.4731013774871826},{"id":"https://openalex.org/C95190672","wikidata":"https://www.wikidata.org/wiki/Q815382","display_name":"Meta-analysis","level":2,"score":0.4664819836616516},{"id":"https://openalex.org/C44249647","wikidata":"https://www.wikidata.org/wiki/Q208498","display_name":"Confidence interval","level":2,"score":0.19221529364585876},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.0},{"id":"https://openalex.org/C120665830","wikidata":"https://www.wikidata.org/wiki/Q14620","display_name":"Optics","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D001943","descriptor_name":"Breast Neoplasms","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D001943","descriptor_name":"Breast Neoplasms","qualifier_ui":"Q000401","qualifier_name":"mortality","is_major_topic":false},{"descriptor_ui":"D001943","descriptor_name":"Breast Neoplasms","qualifier_ui":"Q000517","qualifier_name":"prevention & control","is_major_topic":false},{"descriptor_ui":"D004032","descriptor_name":"Diet","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011446","descriptor_name":"Prospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012306","descriptor_name":"Risk","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014807","descriptor_name":"Vitamin D","qualifier_ui":"Q000031","qualifier_name":"analogs & derivatives","is_major_topic":true},{"descriptor_ui":"D014807","descriptor_name":"Vitamin D","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.1038/bjc.2014.175","doi":"https://doi.org/10.1038/bjc.2014.175","is_oa":true,"landing_page_url":"https://doi.org/10.1038/bjc.2014.175","pdf_url":"https://www.nature.com/articles/bjc2014175.pdf","source":{"id":"https://openalex.org/S62966998","display_name":"British Journal of Cancer","issn_l":"0007-0920","issn":["0007-0920","1532-1827"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319965","host_organization_name":"Springer Nature","host_organization_lineage":["https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Nature"],"type":"journal"},"license":"cc-by-nc-sa","license_id":"https://openalex.org/licenses/cc-by-nc-sa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"British Journal of Cancer","raw_type":"journal-article"},{"id":"pmh:oai:europepmc.org:3405027","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/4037823","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-sa","license_id":"https://openalex.org/licenses/cc-by-nc-sa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:4037823","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/4037823","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-sa","license_id":"https://openalex.org/licenses/cc-by-nc-sa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Br J Cancer","raw_type":"Text"},{"id":"pmid:24714744","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/24714744","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"British journal of cancer","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.1038/bjc.2014.175","doi":"https://doi.org/10.1038/bjc.2014.175","is_oa":true,"landing_page_url":"https://doi.org/10.1038/bjc.2014.175","pdf_url":"https://www.nature.com/articles/bjc2014175.pdf","source":{"id":"https://openalex.org/S62966998","display_name":"British Journal of Cancer","issn_l":"0007-0920","issn":["0007-0920","1532-1827"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319965","host_organization_name":"Springer Nature","host_organization_lineage":["https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Nature"],"type":"journal"},"license":"cc-by-nc-sa","license_id":"https://openalex.org/licenses/cc-by-nc-sa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"British Journal of Cancer","raw_type":"journal-article"},"sustainable_development_goals":[{"score":1.0,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/systematic-review","display_name":"Systematic Review"},{"id":"https://openalex.org/study-designs/meta-analysis","display_name":"Meta-Analysis"}],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W1971199114.pdf","grobid_xml":"https://content.openalex.org/works/W1971199114.grobid-xml"},"referenced_works_count":99,"referenced_works":["https://openalex.org/W1551632868","https://openalex.org/W1605393132","https://openalex.org/W1935650117","https://openalex.org/W1936869709","https://openalex.org/W1964435302","https://openalex.org/W1964611803","https://openalex.org/W1966937335","https://openalex.org/W1970594965","https://openalex.org/W1975946962","https://openalex.org/W1976293750","https://openalex.org/W1979423827","https://openalex.org/W1980897423","https://openalex.org/W1985978829","https://openalex.org/W1989912928","https://openalex.org/W1997209492","https://openalex.org/W1998324851","https://openalex.org/W1999861997","https://openalex.org/W2000743440","https://openalex.org/W2001439861","https://openalex.org/W2001619204","https://openalex.org/W2003493239","https://openalex.org/W2010638654","https://openalex.org/W2012171191","https://openalex.org/W2014358538","https://openalex.org/W2021268614","https://openalex.org/W2022826688","https://openalex.org/W2027983265","https://openalex.org/W2029889262","https://openalex.org/W2034179878","https://openalex.org/W2038177382","https://openalex.org/W2040051569","https://openalex.org/W2041534809","https://openalex.org/W2042948277","https://openalex.org/W2046897290","https://openalex.org/W2063804109","https://openalex.org/W2069317079","https://openalex.org/W2069951308","https://openalex.org/W2071676449","https://openalex.org/W2072975437","https://openalex.org/W2080859080","https://openalex.org/W2080975831","https://openalex.org/W2085491680","https://openalex.org/W2089959409","https://openalex.org/W2096690386","https://openalex.org/W2100732114","https://openalex.org/W2101213151","https://openalex.org/W2102271210","https://openalex.org/W2103273307","https://openalex.org/W2103544702","https://openalex.org/W2104062693","https://openalex.org/W2106787323","https://openalex.org/W2107328434","https://openalex.org/W2107697461","https://openalex.org/W2110242624","https://openalex.org/W2110275373","https://openalex.org/W2115031699","https://openalex.org/W2116986041","https://openalex.org/W2117218060","https://openalex.org/W2118148875","https://openalex.org/W2118323808","https://openalex.org/W2122197362","https://openalex.org/W2122353618","https://openalex.org/W2123346488","https://openalex.org/W2123462672","https://openalex.org/W2124070987","https://openalex.org/W2124466296","https://openalex.org/W2125435699","https://openalex.org/W2127585567","https://openalex.org/W2128415251","https://openalex.org/W2130594468","https://openalex.org/W2134267892","https://openalex.org/W2135017544","https://openalex.org/W2135806783","https://openalex.org/W2143633748","https://openalex.org/W2147837828","https://openalex.org/W2148166852","https://openalex.org/W2148773104","https://openalex.org/W2148885171","https://openalex.org/W2151751946","https://openalex.org/W2153086663","https://openalex.org/W2153383900","https://openalex.org/W2153703864","https://openalex.org/W2154544186","https://openalex.org/W2157304718","https://openalex.org/W2157823046","https://openalex.org/W2159217959","https://openalex.org/W2160477850","https://openalex.org/W2162139093","https://openalex.org/W2162479033","https://openalex.org/W2163507707","https://openalex.org/W2163639538","https://openalex.org/W2165399212","https://openalex.org/W2165647841","https://openalex.org/W2168306115","https://openalex.org/W2169879639","https://openalex.org/W2315123323","https://openalex.org/W2327433559","https://openalex.org/W2762791702","https://openalex.org/W3213529815"],"related_works":["https://openalex.org/W1964611803","https://openalex.org/W2621934578","https://openalex.org/W2997645618","https://openalex.org/W2054278459","https://openalex.org/W2322914626","https://openalex.org/W4313454758","https://openalex.org/W2806149079","https://openalex.org/W3173188269","https://openalex.org/W7101210142","https://openalex.org/W2102700085"],"abstract_inverted_index":{"BACKGROUND:":[0],"Experimental":[1],"studies":[2,36,81],"suggest":[3,180],"potential":[4],"anti-carcinogenic":[5],"properties":[6],"of":[7,78,111,172],"vitamin":[8,42,121,183],"D":[9,43,51,122,184],"against":[10],"breast":[11,54,89,105,112,140,152,191,199],"cancer":[12,55,90,106,113,141,153,192,200],"risk,":[13],"but":[14,194],"the":[15,39,116,119],"epidemiological":[16],"evidence":[17,171],"to":[18,37,67],"date":[19],"is":[20,186],"inconsistent.":[21],"METHODS:":[22],"We":[23],"searched":[24],"MEDLINE":[25],"and":[26,48,53,124,133,160,174],"EMBASE":[27],"databases":[28],"along":[29],"with":[30,150,189,197],"a":[31,60,69],"hand":[32],"search":[33],"for":[34,88,115],"eligible":[35],"examine":[38],"association":[40],"between":[41],"status":[44,185],"(based":[45],"on":[46],"diet":[47],"blood":[49,125,144],"25-hydroxyvitamin":[50],"(25(OH)D))":[52],"risk":[56,73,193],"or":[57,84,97],"mortality":[58,98,154,162],"in":[59],"meta-analysis.":[61],"A":[62,76],"random-effect":[63],"model":[64],"was":[65,169],"used":[66],"calculate":[68],"pooled":[70,109],"adjusted":[71],"relative":[72],"(RR).":[74],"RESULTS:":[75],"total":[77],"30":[79],"prospective":[80],"(nested":[82],"case-control":[83],"cohort)":[85],"were":[86,128,147],"included":[87],"incidence":[91,114],"(n=24":[92],"studies;":[93,100],"31":[94],"867":[95],"cases)":[96],"(n=6":[99],"870":[101],"deaths)":[102],"among":[103],"6092":[104],"patients.":[107],"The":[108],"RRs":[110],"highest":[117],"vs":[118],"lowest":[120],"intake":[123],"25(OH)D":[126,145],"levels":[127,146],"0.95":[129],"(95%":[130,135],"CI:":[131,136,158,166],"0.88-1.01)":[132],"0.92":[134],"0.83-1.02),":[137],"respectively.":[138],"Among":[139],"patients,":[142],"high":[143,182],"significantly":[148],"associated":[149,188,196],"lower":[151],"(pooled":[155,163],"RR=0.58,":[156],"95%":[157,165],"0.40-0.85)":[159],"overall":[161],"RR=0.61,":[164],"0.48-0.79).":[167],"There":[168],"no":[170],"heterogeneity":[173],"publication":[175],"bias.":[176],"CONCLUSIONS:":[177],"Our":[178],"findings":[179],"that":[181],"weakly":[187],"low":[190],"strongly":[195],"better":[198],"survival.":[201]},"counts_by_year":[{"year":2026,"cited_by_count":9},{"year":2025,"cited_by_count":11},{"year":2024,"cited_by_count":9},{"year":2023,"cited_by_count":10},{"year":2022,"cited_by_count":16},{"year":2021,"cited_by_count":14},{"year":2020,"cited_by_count":15},{"year":2019,"cited_by_count":26},{"year":2018,"cited_by_count":28},{"year":2017,"cited_by_count":22},{"year":2016,"cited_by_count":17},{"year":2015,"cited_by_count":14},{"year":2014,"cited_by_count":3},{"year":2013,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}