{"id":"https://openalex.org/W1971134853","doi":"https://doi.org/10.1002/j.1536-4801.1991.tb10246.x","title":"Severe Infantile Colic and Food Intolerance","display_name":"Severe Infantile Colic and Food Intolerance","publication_year":1991,"publication_date":"1991-04-01","ids":{"openalex":"https://openalex.org/W1971134853","doi":"https://doi.org/10.1002/j.1536-4801.1991.tb10246.x","mag":"1971134853","pmid":"https://pubmed.ncbi.nlm.nih.gov/2072224"},"language":"en","primary_location":{"id":"doi:10.1002/j.1536-4801.1991.tb10246.x","doi":"https://doi.org/10.1002/j.1536-4801.1991.tb10246.x","is_oa":false,"landing_page_url":"https://doi.org/10.1002/j.1536-4801.1991.tb10246.x","pdf_url":null,"source":{"id":"https://openalex.org/S197964821","display_name":"Journal of Pediatric Gastroenterology and Nutrition","issn_l":"0277-2116","issn":["0277-2116","1536-4801"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Pediatric Gastroenterology and Nutrition","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5107447760","display_name":"Giuseppe Iacono","orcid":"https://orcid.org/0000-0002-1527-0754","observed_orcids":["https://orcid.org/0000-0002-1527-0754"]},"institutions":[{"id":"https://openalex.org/I900890020","display_name":"University of Palermo","ror":"https://ror.org/044k9ta02","country_code":"IT","type":"education","lineage":["https://openalex.org/I900890020"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Giuseppe Iacono","raw_affiliation_strings":["IV Divisione Lattanti Ospedale G. Di Cristina Universita Di Palermo Palermo Italy","Cattedra Di Patologia Medica, Universita Di Palermo, Palermo, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"IV Divisione Lattanti Ospedale G. Di Cristina Universita Di Palermo Palermo Italy","institution_ids":["https://openalex.org/I900890020"]},{"raw_affiliation_string":"Cattedra Di Patologia Medica, Universita Di Palermo, Palermo, Italy","institution_ids":["https://openalex.org/I900890020"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5088747314","display_name":"Antonio Carroccio","orcid":"https://orcid.org/0000-0001-8913-7916","observed_orcids":["https://orcid.org/0000-0001-8913-7916"]},"institutions":[{"id":"https://openalex.org/I900890020","display_name":"University of Palermo","ror":"https://ror.org/044k9ta02","country_code":"IT","type":"education","lineage":["https://openalex.org/I900890020"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Antomio Carroccio","raw_affiliation_strings":["Cattedra Di Patologia Medica, Universita Di Palermo, Palermo, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cattedra Di Patologia Medica, Universita Di Palermo, Palermo, Italy","institution_ids":["https://openalex.org/I900890020"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5082733849","display_name":"Giuseppe Montalto","orcid":"https://orcid.org/0000-0002-8731-8577","observed_orcids":["https://orcid.org/0000-0002-8731-8577"]},"institutions":[{"id":"https://openalex.org/I900890020","display_name":"University of Palermo","ror":"https://ror.org/044k9ta02","country_code":"IT","type":"education","lineage":["https://openalex.org/I900890020"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Giuseppe Montalto","raw_affiliation_strings":["Cattedra Di Patologia Medica, Universita Di Palermo, Palermo, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cattedra Di Patologia Medica, Universita Di Palermo, Palermo, Italy","institution_ids":["https://openalex.org/I900890020"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5076895078","display_name":"Francesca Cavataio","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I900890020","display_name":"University of Palermo","ror":"https://ror.org/044k9ta02","country_code":"IT","type":"education","lineage":["https://openalex.org/I900890020"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Francesca Cavataio","raw_affiliation_strings":["IV Divisione Lattanti Ospedale G. Di Cristina Universita Di Palermo Palermo Italy","Cattedra Di Patologia Medica, Universita Di Palermo, Palermo, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"IV Divisione Lattanti Ospedale G. Di Cristina Universita Di Palermo Palermo Italy","institution_ids":["https://openalex.org/I900890020"]},{"raw_affiliation_string":"Cattedra Di Patologia Medica, Universita Di Palermo, Palermo, Italy","institution_ids":["https://openalex.org/I900890020"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5067558767","display_name":"Elisabetta Bragion","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I900890020","display_name":"University of Palermo","ror":"https://ror.org/044k9ta02","country_code":"IT","type":"education","lineage":["https://openalex.org/I900890020"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Elisabetta Bragion","raw_affiliation_strings":["IV Divisione Lattanti Ospedale G. Di Cristina Universita Di Palermo Palermo Italy","Cattedra Di Patologia Medica, Universita Di Palermo, Palermo, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"IV Divisione Lattanti Ospedale G. Di Cristina Universita Di Palermo Palermo Italy","institution_ids":["https://openalex.org/I900890020"]},{"raw_affiliation_string":"Cattedra Di Patologia Medica, Universita Di Palermo, Palermo, Italy","institution_ids":["https://openalex.org/I900890020"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5046532529","display_name":"Domenico Lorello","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I900890020","display_name":"University of Palermo","ror":"https://ror.org/044k9ta02","country_code":"IT","type":"education","lineage":["https://openalex.org/I900890020"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Domenico Lorello","raw_affiliation_strings":["Cattedra Di Patologia Medica, Universita Di Palermo, Palermo, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cattedra Di Patologia Medica, Universita Di Palermo, Palermo, Italy","institution_ids":["https://openalex.org/I900890020"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5085816895","display_name":"Vincenzo Balsamo","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I900890020","display_name":"University of Palermo","ror":"https://ror.org/044k9ta02","country_code":"IT","type":"education","lineage":["https://openalex.org/I900890020"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Vincenzo Balsamo","raw_affiliation_strings":["IV Divisione Lattanti Ospedale G. Di Cristina Universita Di Palermo Palermo Italy","Cattedra Di Patologia Medica, Universita Di Palermo, Palermo, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"IV Divisione Lattanti Ospedale G. Di Cristina Universita Di Palermo Palermo Italy","institution_ids":["https://openalex.org/I900890020"]},{"raw_affiliation_string":"Cattedra Di Patologia Medica, Universita Di Palermo, Palermo, Italy","institution_ids":["https://openalex.org/I900890020"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5108105144","display_name":"Alberto Notarbartolo","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I900890020","display_name":"University of Palermo","ror":"https://ror.org/044k9ta02","country_code":"IT","type":"education","lineage":["https://openalex.org/I900890020"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Alberto Notarbartolo","raw_affiliation_strings":["Cattedra Di Patologia Medica, Universita Di Palermo, Palermo, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cattedra Di Patologia Medica, Universita Di Palermo, Palermo, Italy","institution_ids":["https://openalex.org/I900890020"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I900890020"],"apc_list":{"value":3780,"currency":"USD","value_usd":3780},"apc_paid":null,"fwci":6.9622,"has_fulltext":false,"cited_by_count":98,"citation_normalized_percentile":{"value":0.96312231,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":99},"biblio":{"volume":"12","issue":"3","first_page":"332","last_page":"335"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T13289","display_name":"Infant Health and Development","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/3611","display_name":"Pharmacy"},"field":{"id":"https://openalex.org/fields/36","display_name":"Health Professions"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T13289","display_name":"Infant Health and Development","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/3611","display_name":"Pharmacy"},"field":{"id":"https://openalex.org/fields/36","display_name":"Health Professions"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11294","display_name":"Infant Nutrition and Health","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2916","display_name":"Nutrition and Dietetics"},"field":{"id":"https://openalex.org/fields/29","display_name":"Nursing"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10365","display_name":"Gastrointestinal motility and disorders","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2715","display_name":"Gastroenterology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/infantile-colic","display_name":"infantile colic","score":0.9990000128746033},{"id":"https://openalex.org/keywords/cow-s-milk-protein-intolerance","display_name":"cow's milk protein intolerance","score":0.9959999918937683},{"id":"https://openalex.org/keywords/formula-fed-infants","display_name":"formula-fed infants","score":0.6840000152587891},{"id":"https://openalex.org/keywords/dietary-challenge","display_name":"dietary challenge","score":0.4869999885559082},{"id":"https://openalex.org/keywords/atopy","display_name":"atopy","score":0.8930000066757202},{"id":"https://openalex.org/keywords/infant-crying","display_name":"infant crying","score":0.5809999704360962},{"id":"https://openalex.org/keywords/dietary-therapy","display_name":"dietary therapy","score":0.6420000195503235}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9500569105148315},{"id":"https://openalex.org/C2910404990","wikidata":"https://www.wikidata.org/wiki/Q1370346","display_name":"Infantile colic","level":3,"score":0.8570611476898193},{"id":"https://openalex.org/C2778013503","wikidata":"https://www.wikidata.org/wiki/Q152247","display_name":"Crying","level":2,"score":0.8149791955947876},{"id":"https://openalex.org/C145333580","wikidata":"https://www.wikidata.org/wiki/Q260946","display_name":"Anamnesis","level":2,"score":0.6622812747955322},{"id":"https://openalex.org/C187212893","wikidata":"https://www.wikidata.org/wiki/Q123028","display_name":"Pediatrics","level":1,"score":0.5625959038734436},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.5054430961608887},{"id":"https://openalex.org/C2777697326","wikidata":"https://www.wikidata.org/wiki/Q757678","display_name":"Atopy","level":3,"score":0.4836962819099426},{"id":"https://openalex.org/C2777903966","wikidata":"https://www.wikidata.org/wiki/Q1727229","display_name":"Food intolerance","level":3,"score":0.4218476712703705},{"id":"https://openalex.org/C207480886","wikidata":"https://www.wikidata.org/wiki/Q42982","display_name":"Allergy","level":2,"score":0.41817429661750793},{"id":"https://openalex.org/C90924648","wikidata":"https://www.wikidata.org/wiki/Q120569","display_name":"Gastroenterology","level":1,"score":0.4180675745010376},{"id":"https://openalex.org/C2776042228","wikidata":"https://www.wikidata.org/wiki/Q35869","display_name":"Asthma","level":2,"score":0.1643509566783905},{"id":"https://openalex.org/C118552586","wikidata":"https://www.wikidata.org/wiki/Q7867","display_name":"Psychiatry","level":1,"score":0.0},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D003085","descriptor_name":"Colic","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005500","descriptor_name":"Follow-Up Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005512","descriptor_name":"Food Hypersensitivity","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006967","descriptor_name":"Hypersensitivity","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D007223","descriptor_name":"Infant","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007225","descriptor_name":"Infant Food","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":false},{"descriptor_ui":"D007231","descriptor_name":"Infant, Newborn","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008894","descriptor_name":"Milk Proteins","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":true},{"descriptor_ui":"D011446","descriptor_name":"Prospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016269","descriptor_name":"Milk Hypersensitivity","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":true},{"descriptor_ui":"D016269","descriptor_name":"Milk Hypersensitivity","qualifier_ui":"Q000178","qualifier_name":"diet therapy","is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1002/j.1536-4801.1991.tb10246.x","doi":"https://doi.org/10.1002/j.1536-4801.1991.tb10246.x","is_oa":false,"landing_page_url":"https://doi.org/10.1002/j.1536-4801.1991.tb10246.x","pdf_url":null,"source":{"id":"https://openalex.org/S197964821","display_name":"Journal of Pediatric Gastroenterology and Nutrition","issn_l":"0277-2116","issn":["0277-2116","1536-4801"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Pediatric Gastroenterology and Nutrition","raw_type":"journal-article"},{"id":"doi:10.1097/00005176-199104000-00008","doi":"https://doi.org/10.1097/00005176-199104000-00008","is_oa":false,"landing_page_url":"https://doi.org/10.1097/00005176-199104000-00008","pdf_url":null,"source":{"id":"https://openalex.org/S197964821","display_name":"Journal of Pediatric Gastroenterology and Nutrition","issn_l":"0277-2116","issn":["0277-2116","1536-4801"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Pediatric Gastroenterology and Nutrition","raw_type":"journal-article"},{"id":"pmid:2072224","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/2072224","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of pediatric gastroenterology and nutrition","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.98580002784729,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"},{"score":0.4359000027179718,"id":"https://metadata.un.org/sdg/2","display_name":"Zero hunger"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W1530242592","https://openalex.org/W2404691213","https://openalex.org/W4416312756","https://openalex.org/W1530421772","https://openalex.org/W4385067891","https://openalex.org/W2057915253","https://openalex.org/W2023107778","https://openalex.org/W1950123675","https://openalex.org/W1995378516","https://openalex.org/W4414962745"],"abstract_inverted_index":{"To":[0],"determine":[1],"the":[2,51,54,72,78,99,133,164,181],"relationship":[3],"between":[4],"infantile":[5],"colic":[6,33,103,113,137,147,168],"and":[7,104,138,172],"cow's":[8,65],"milk":[9,66],"protein":[10,67],"intolerance":[11,152],"(CMPI)":[12],"in":[13,53,82,94,105,174],"formula-fed":[14],"infants,":[15],"70":[16],"infants":[17,52,134,165],"(38":[18],"male,":[19],"32":[20],"female)":[21],"were":[22],"selected,":[23],"with":[24,31,101,111,135,145,166],"mean":[25,124],"age":[26],"30.2":[27],"+/-":[28],"21.4":[29],"days,":[30],"severe":[32,167],"(duration":[34],"of":[35,50,62,80,96,98,107,109,121,129,132,140,143,163],"crying":[36],"greater":[37,115],"than":[38,116,155],"4":[39],"h":[40],"per":[41,46],"day":[42],"for":[43,92],"5":[44],"days":[45],"week).":[47],"In":[48],"50":[49,85,97,130],"study":[55],"group":[56],"(71.4%)":[57],"there":[58],"was":[59,69,88],"a":[60,89,160],"remission":[61],"symptoms":[63,81],"when":[64],"(CMP)":[68],"eliminated":[70],"from":[71],"diet.":[73],"Two":[74],"successive":[75],"challenges":[76],"caused":[77],"return":[79],"all":[83],"these":[84,175],"infants.":[86],"There":[87],"positive":[90],"anamnesis":[91],"atopy":[93],"9":[95],"patients":[100],"CMP-related":[102,136],"1":[106,139],"20":[108,141],"those":[110,144],"non-CMP-related":[112,146],"(p":[114,153],"0.05).":[117],"A":[118],"follow-up":[119],"period":[120],"18":[122],"months'":[123],"duration":[125],"showed":[126],"that":[127,159,173],"22":[128],"(44%)":[131],"(5%)":[142],"developed":[148],"an":[149],"overt":[150],"alimentary":[151],"less":[154],"0.02).":[156],"We":[157],"conclude":[158],"considerable":[161],"percentage":[162],"also":[169],"have":[170],"CMPI":[171],"cases,":[176],"dietetic":[177],"treatment":[178],"should":[179],"be":[180],"first":[182],"therapeutic":[183],"approach.":[184]},"counts_by_year":[{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":3},{"year":2018,"cited_by_count":2},{"year":2017,"cited_by_count":2},{"year":2016,"cited_by_count":6},{"year":2015,"cited_by_count":7},{"year":2014,"cited_by_count":3},{"year":2013,"cited_by_count":5},{"year":2012,"cited_by_count":3}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}