{"id":"https://openalex.org/W1970856490","doi":"https://doi.org/10.1016/s0272-5231(02)00051-5","title":"Local and systemic thrombolytic therapy for acute venous thromboembolism","display_name":"Local and systemic thrombolytic therapy for acute venous thromboembolism","publication_year":2003,"publication_date":"2003-03-01","ids":{"openalex":"https://openalex.org/W1970856490","doi":"https://doi.org/10.1016/s0272-5231(02)00051-5","mag":"1970856490","pmid":"https://pubmed.ncbi.nlm.nih.gov/12688249"},"language":"en","primary_location":{"id":"doi:10.1016/s0272-5231(02)00051-5","doi":"https://doi.org/10.1016/s0272-5231(02)00051-5","is_oa":false,"landing_page_url":"https://doi.org/10.1016/s0272-5231(02)00051-5","pdf_url":null,"source":{"id":"https://openalex.org/S42926609","display_name":"Clinics in Chest Medicine","issn_l":"0272-5231","issn":["0272-5231","1557-8216"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clinics in Chest Medicine","raw_type":"journal-article"},"volume":null,"type":"review","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5054960222","display_name":"Selim M. Arcasoy","orcid":"https://orcid.org/0000-0003-1906-8577","observed_orcids":["https://orcid.org/0000-0003-1906-8577"]},"institutions":[{"id":"https://openalex.org/I1340179700","display_name":"NewYork\u2013Presbyterian Hospital","ror":"https://ror.org/03gzbrs57","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1340179700"]},{"id":"https://openalex.org/I205783295","display_name":"Cornell University","ror":"https://ror.org/05bnh6r87","country_code":"US","type":"education","lineage":["https://openalex.org/I205783295"]},{"id":"https://openalex.org/I78577930","display_name":"Columbia University","ror":"https://ror.org/00hj8s172","country_code":"US","type":"education","lineage":["https://openalex.org/I78577930"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Selim M Arcasoy","raw_affiliation_strings":["Pulmonary, Allergy, and Critical Care Division, Columbia University College of Physicians and Surgeons, Lung Transplantation Program, New York Presbyterian Hospital of Columbia, Cornell University, New York, NY 10032, USA. sa2059@columbia.edu","Lung Transplantation Program, New York Presbyterian Hospital of Columbia and Cornell University, 622 West 168 Street, New York, NY 10032, USA","Pulmonary, Allergy, and Critical Care Division, Columbia University College of Physicians and Surgeons, 622 West 168th Street, New York, NY 10032, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Pulmonary, Allergy, and Critical Care Division, Columbia University College of Physicians and Surgeons, Lung Transplantation Program, New York Presbyterian Hospital of Columbia, Cornell University, New York, NY 10032, USA. sa2059@columbia.edu","institution_ids":["https://openalex.org/I1340179700","https://openalex.org/I205783295","https://openalex.org/I78577930"]},{"raw_affiliation_string":"Lung Transplantation Program, New York Presbyterian Hospital of Columbia and Cornell University, 622 West 168 Street, New York, NY 10032, USA","institution_ids":["https://openalex.org/I1340179700","https://openalex.org/I205783295"]},{"raw_affiliation_string":"Pulmonary, Allergy, and Critical Care Division, Columbia University College of Physicians and Surgeons, 622 West 168th Street, New York, NY 10032, USA","institution_ids":["https://openalex.org/I78577930"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5037072010","display_name":"Anil Vachani","orcid":"https://orcid.org/0000-0002-3871-8697","observed_orcids":["https://orcid.org/0000-0002-3871-8697"]},"institutions":[{"id":"https://openalex.org/I79576946","display_name":"University of Pennsylvania","ror":"https://ror.org/00b30xv10","country_code":"US","type":"education","lineage":["https://openalex.org/I79576946"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Anil Vachani","raw_affiliation_strings":["Pulmonary, Allergy, and Critical Care Division, University of Pennsylvania School of Medicine, 3400 Spruce Street, Philadelphia, PA 19104, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Pulmonary, Allergy, and Critical Care Division, University of Pennsylvania School of Medicine, 3400 Spruce Street, Philadelphia, PA 19104, USA","institution_ids":["https://openalex.org/I79576946"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5054960222"],"corresponding_institution_ids":["https://openalex.org/I1340179700","https://openalex.org/I205783295","https://openalex.org/I78577930"],"apc_list":{"value":3350,"currency":"USD","value_usd":3350},"apc_paid":null,"fwci":0.8086,"has_fulltext":false,"cited_by_count":39,"citation_normalized_percentile":{"value":0.60769231,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":98},"biblio":{"volume":"24","issue":"1","first_page":"73","last_page":"91"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10285","display_name":"Venous Thromboembolism Diagnosis and Management","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2724","display_name":"Internal Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10285","display_name":"Venous Thromboembolism Diagnosis and Management","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2724","display_name":"Internal Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10881","display_name":"Blood Coagulation and Thrombosis Mechanisms","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10227","display_name":"Acute Ischemic Stroke Management","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/thrombolysis","display_name":"thrombolysis","score":0.996999979019165},{"id":"https://openalex.org/keywords/venous-thromboembolism","display_name":"venous thromboembolism","score":0.9340000152587891},{"id":"https://openalex.org/keywords/pulmonary-embolism","display_name":"pulmonary embolism","score":0.9580000042915344},{"id":"https://openalex.org/keywords/deep-vein-thrombosis","display_name":"deep vein thrombosis","score":0.996999979019165},{"id":"https://openalex.org/keywords/catheter-directed-thrombolysis","display_name":"catheter-directed thrombolysis","score":0.921999990940094},{"id":"https://openalex.org/keywords/bleeding-risk","display_name":"bleeding risk","score":0.8180000185966492},{"id":"https://openalex.org/keywords/right-ventricular-dysfunction","display_name":"right ventricular dysfunction","score":0.8109999895095825},{"id":"https://openalex.org/keywords/phlegmasia-cerulea-dolens","display_name":"phlegmasia cerulea dolens","score":0.9070000052452087},{"id":"https://openalex.org/keywords/iliofemoral-deep-vein-thrombosis","display_name":"iliofemoral deep vein thrombosis","score":0.9160000085830688},{"id":"https://openalex.org/keywords/anticoagulation","display_name":"anticoagulation","score":0.6919999718666077},{"id":"https://openalex.org/keywords/risk-benefit-assessment","display_name":"risk-benefit assessment","score":0.7059999704360962}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9685102701187134},{"id":"https://openalex.org/C2779581417","wikidata":"https://www.wikidata.org/wiki/Q1931577","display_name":"Thrombolysis","level":3,"score":0.8111428022384644},{"id":"https://openalex.org/C177713679","wikidata":"https://www.wikidata.org/wiki/Q679690","display_name":"Intensive care medicine","level":1,"score":0.6751091480255127},{"id":"https://openalex.org/C2776265017","wikidata":"https://www.wikidata.org/wiki/Q220570","display_name":"Pulmonary embolism","level":2,"score":0.5504027605056763},{"id":"https://openalex.org/C2780868729","wikidata":"https://www.wikidata.org/wiki/Q261327","display_name":"Thrombosis","level":2,"score":0.5253868699073792},{"id":"https://openalex.org/C2909817843","wikidata":"https://www.wikidata.org/wiki/Q575222","display_name":"Fibrinolytic agent","level":3,"score":0.46368521451950073},{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.3125671148300171},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.2882678806781769},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.27214598655700684},{"id":"https://openalex.org/C500558357","wikidata":"https://www.wikidata.org/wiki/Q12152","display_name":"Myocardial infarction","level":2,"score":0.27115821838378906},{"id":"https://openalex.org/C2776572282","wikidata":"https://www.wikidata.org/wiki/Q416351","display_name":"Tissue plasminogen activator","level":2,"score":0.18300998210906982}],"mesh":[{"descriptor_ui":"D000208","descriptor_name":"Acute Disease","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000925","descriptor_name":"Anticoagulants","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":false},{"descriptor_ui":"D000925","descriptor_name":"Anticoagulants","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D005343","descriptor_name":"Fibrinolytic Agents","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":false},{"descriptor_ui":"D005343","descriptor_name":"Fibrinolytic Agents","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D006470","descriptor_name":"Hemorrhage","qualifier_ui":"Q000139","qualifier_name":"chemically induced","is_major_topic":false},{"descriptor_ui":"D006493","descriptor_name":"Heparin","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":false},{"descriptor_ui":"D006493","descriptor_name":"Heparin","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011655","descriptor_name":"Pulmonary Embolism","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D012307","descriptor_name":"Risk Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015912","descriptor_name":"Thrombolytic Therapy","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":false},{"descriptor_ui":"D020246","descriptor_name":"Venous Thrombosis","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1016/s0272-5231(02)00051-5","doi":"https://doi.org/10.1016/s0272-5231(02)00051-5","is_oa":false,"landing_page_url":"https://doi.org/10.1016/s0272-5231(02)00051-5","pdf_url":null,"source":{"id":"https://openalex.org/S42926609","display_name":"Clinics in Chest Medicine","issn_l":"0272-5231","issn":["0272-5231","1557-8216"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clinics in Chest Medicine","raw_type":"journal-article"},{"id":"pmid:12688249","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/12688249","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clinics in chest medicine","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.9940000176429749}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":129,"referenced_works":["https://openalex.org/W14876985","https://openalex.org/W59092716","https://openalex.org/W74544974","https://openalex.org/W1510542347","https://openalex.org/W1519035408","https://openalex.org/W1963915169","https://openalex.org/W1965505881","https://openalex.org/W1967590441","https://openalex.org/W1969992146","https://openalex.org/W1973700638","https://openalex.org/W1975369179","https://openalex.org/W1978280229","https://openalex.org/W1978830177","https://openalex.org/W1980150722","https://openalex.org/W1985793838","https://openalex.org/W1987892547","https://openalex.org/W1988768919","https://openalex.org/W1989722026","https://openalex.org/W1992725980","https://openalex.org/W1994003549","https://openalex.org/W1994196027","https://openalex.org/W1995077918","https://openalex.org/W1995792758","https://openalex.org/W1996930100","https://openalex.org/W2001027084","https://openalex.org/W2002063880","https://openalex.org/W2004746725","https://openalex.org/W2006290430","https://openalex.org/W2007943712","https://openalex.org/W2009344499","https://openalex.org/W2010037589","https://openalex.org/W2011195183","https://openalex.org/W2012042329","https://openalex.org/W2012519169","https://openalex.org/W2016010643","https://openalex.org/W2016609963","https://openalex.org/W2018076981","https://openalex.org/W2020900565","https://openalex.org/W2021112959","https://openalex.org/W2022993510","https://openalex.org/W2023676155","https://openalex.org/W2025178523","https://openalex.org/W2025493142","https://openalex.org/W2026971812","https://openalex.org/W2028678981","https://openalex.org/W2028916703","https://openalex.org/W2032284721","https://openalex.org/W2033019253","https://openalex.org/W2034609942","https://openalex.org/W2034937886","https://openalex.org/W2038296306","https://openalex.org/W2039059007","https://openalex.org/W2041176958","https://openalex.org/W2049485678","https://openalex.org/W2053156671","https://openalex.org/W2055149347","https://openalex.org/W2057440193","https://openalex.org/W2058162669","https://openalex.org/W2060181010","https://openalex.org/W2064562336","https://openalex.org/W2065734474","https://openalex.org/W2067224694","https://openalex.org/W2067497366","https://openalex.org/W2069054188","https://openalex.org/W2074335635","https://openalex.org/W2076023803","https://openalex.org/W2076894322","https://openalex.org/W2081071955","https://openalex.org/W2087646765","https://openalex.org/W2088267193","https://openalex.org/W2090260054","https://openalex.org/W2090735669","https://openalex.org/W2094499590","https://openalex.org/W2100024898","https://openalex.org/W2100487920","https://openalex.org/W2101914650","https://openalex.org/W2102535207","https://openalex.org/W2103326534","https://openalex.org/W2105361932","https://openalex.org/W2110664285","https://openalex.org/W2111314273","https://openalex.org/W2113247869","https://openalex.org/W2113731416","https://openalex.org/W2115785998","https://openalex.org/W2116925291","https://openalex.org/W2120934774","https://openalex.org/W2126286036","https://openalex.org/W2129034871","https://openalex.org/W2131643596","https://openalex.org/W2131991901","https://openalex.org/W2135550093","https://openalex.org/W2140440432","https://openalex.org/W2141615647","https://openalex.org/W2142615152","https://openalex.org/W2143381739","https://openalex.org/W2144607086","https://openalex.org/W2148653105","https://openalex.org/W2149789266","https://openalex.org/W2154760417","https://openalex.org/W2155721369","https://openalex.org/W2160443953","https://openalex.org/W2162113752","https://openalex.org/W2163414191","https://openalex.org/W2164268628","https://openalex.org/W2167955183","https://openalex.org/W2171145855","https://openalex.org/W2225444107","https://openalex.org/W2312814626","https://openalex.org/W2313589877","https://openalex.org/W2317651226","https://openalex.org/W2328171462","https://openalex.org/W2331379301","https://openalex.org/W2332974935","https://openalex.org/W2340468754","https://openalex.org/W2398701378","https://openalex.org/W2400240907","https://openalex.org/W2401897071","https://openalex.org/W2409159451","https://openalex.org/W2416257861","https://openalex.org/W2418205415","https://openalex.org/W2464710386","https://openalex.org/W2464916660","https://openalex.org/W2469258259","https://openalex.org/W2593959884","https://openalex.org/W2975834859","https://openalex.org/W2987921488","https://openalex.org/W4236981756","https://openalex.org/W4249634582","https://openalex.org/W4294109446"],"related_works":["https://openalex.org/W3106883851","https://openalex.org/W2094696806","https://openalex.org/W2066286151","https://openalex.org/W1999289070","https://openalex.org/W2315006141","https://openalex.org/W2588928265","https://openalex.org/W1977601399","https://openalex.org/W1517803719","https://openalex.org/W3048888549","https://openalex.org/W4309662948"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2023,"cited_by_count":1},{"year":2019,"cited_by_count":1},{"year":2016,"cited_by_count":1},{"year":2015,"cited_by_count":1},{"year":2013,"cited_by_count":4},{"year":2012,"cited_by_count":2}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}