{"id":"https://openalex.org/W1970758387","doi":"https://doi.org/10.1002/1097-0142(195811/12)11:6<1187::aid-cncr2820110613>3.0.co;2-r","title":"Hormonal therapy in cancer of the breast, XIII. The effect of 9\u03b1-fluoro-17\u03b1-methyl-\u03944-androsten-3-one-11\u03b2,17\u03b2-diol (fluoxymesterone) therapy on clinical course and hormonal excretion","display_name":"Hormonal therapy in cancer of the breast, XIII. The effect of 9\u03b1-fluoro-17\u03b1-methyl-\u03944-androsten-3-one-11\u03b2,17\u03b2-diol (fluoxymesterone) therapy on clinical course and hormonal excretion","publication_year":1958,"publication_date":"1958-11-01","ids":{"openalex":"https://openalex.org/W1970758387","doi":"https://doi.org/10.1002/1097-0142(195811/12)11:6<1187::aid-cncr2820110613>3.0.co;2-r","mag":"1970758387","pmid":"https://pubmed.ncbi.nlm.nih.gov/13608419"},"language":"en","primary_location":{"id":"doi:10.1002/1097-0142(195811/12)11:6<1187::aid-cncr2820110613>3.0.co;2-r","doi":"https://doi.org/10.1002/1097-0142(195811/12)11:6<1187::aid-cncr2820110613>3.0.co;2-r","is_oa":true,"landing_page_url":"https://doi.org/10.1002/1097-0142(195811/12)11:6<1187::aid-cncr2820110613>3.0.co;2-r","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/1097-0142%28195811/12%2911%3A6%3C1187%3A%3AAID-CNCR2820110613%3E3.0.CO%3B2-R","source":{"id":"https://openalex.org/S126033908","display_name":"Cancer","issn_l":"0008-543X","issn":["0008-543X","1045-7410","1097-0142"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cancer","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/1097-0142%28195811/12%2911%3A6%3C1187%3A%3AAID-CNCR2820110613%3E3.0.CO%3B2-R","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5113492734","display_name":"Albert Segaloff","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I114832834","display_name":"Tulane University","ror":"https://ror.org/04vmvtb21","country_code":"US","type":"education","lineage":["https://openalex.org/I114832834"]},{"id":"https://openalex.org/I2799767083","display_name":"Ochsner Medical Center","ror":"https://ror.org/0290qyp66","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1336053918","https://openalex.org/I2799767083"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Albert Segaloff","raw_affiliation_strings":["Endocrine Research Laboratory of the Alton Ochsner Medical Foundation; the Department of Medicine, Tulane University School of Medicine, and Charty Hospital of Louisiana, New Orleans, La","Endocrine Research Laboratory of the Alton Ochsner Medical Foundation","the Department of Medicine, Tulane University School of Medicine, and Charty Hospital of Louisiana, New Orleans, La"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Endocrine Research Laboratory of the Alton Ochsner Medical Foundation; the Department of Medicine, Tulane University School of Medicine, and Charty Hospital of Louisiana, New Orleans, La","institution_ids":["https://openalex.org/I114832834","https://openalex.org/I2799767083"]},{"raw_affiliation_string":"Endocrine Research Laboratory of the Alton Ochsner Medical Foundation","institution_ids":["https://openalex.org/I2799767083"]},{"raw_affiliation_string":"the Department of Medicine, Tulane University School of Medicine, and Charty Hospital of Louisiana, New Orleans, La","institution_ids":["https://openalex.org/I114832834"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111274614","display_name":"C. Y. Bowers","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I114832834","display_name":"Tulane University","ror":"https://ror.org/04vmvtb21","country_code":"US","type":"education","lineage":["https://openalex.org/I114832834"]},{"id":"https://openalex.org/I2799767083","display_name":"Ochsner Medical Center","ror":"https://ror.org/0290qyp66","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1336053918","https://openalex.org/I2799767083"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"C. Y. Bowers","raw_affiliation_strings":["Endocrine Research Laboratory of the Alton Ochsner Medical Foundation; the Department of Medicine, Tulane University School of Medicine, and Charty Hospital of Louisiana, New Orleans, La","Endocrine Research Laboratory of the Alton Ochsner Medical Foundation","the Department of Medicine, Tulane University School of Medicine, and Charty Hospital of Louisiana, New Orleans, La"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Endocrine Research Laboratory of the Alton Ochsner Medical Foundation; the Department of Medicine, Tulane University School of Medicine, and Charty Hospital of Louisiana, New Orleans, La","institution_ids":["https://openalex.org/I114832834","https://openalex.org/I2799767083"]},{"raw_affiliation_string":"Endocrine Research Laboratory of the Alton Ochsner Medical Foundation","institution_ids":["https://openalex.org/I2799767083"]},{"raw_affiliation_string":"the Department of Medicine, Tulane University School of Medicine, and Charty Hospital of Louisiana, New Orleans, La","institution_ids":["https://openalex.org/I114832834"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5052987248","display_name":"Edward L. Rongone","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I114832834","display_name":"Tulane University","ror":"https://ror.org/04vmvtb21","country_code":"US","type":"education","lineage":["https://openalex.org/I114832834"]},{"id":"https://openalex.org/I2799767083","display_name":"Ochsner Medical Center","ror":"https://ror.org/0290qyp66","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1336053918","https://openalex.org/I2799767083"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Edward L. Rongone","raw_affiliation_strings":["Endocrine Research Laboratory of the Alton Ochsner Medical Foundation; the Department of Medicine, Tulane University School of Medicine, and Charty Hospital of Louisiana, New Orleans, La","Endocrine Research Laboratory of the Alton Ochsner Medical Foundation","the Department of Medicine, Tulane University School of Medicine, and Charty Hospital of Louisiana, New Orleans, La"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Endocrine Research Laboratory of the Alton Ochsner Medical Foundation; the Department of Medicine, Tulane University School of Medicine, and Charty Hospital of Louisiana, New Orleans, La","institution_ids":["https://openalex.org/I114832834","https://openalex.org/I2799767083"]},{"raw_affiliation_string":"Endocrine Research Laboratory of the Alton Ochsner Medical Foundation","institution_ids":["https://openalex.org/I2799767083"]},{"raw_affiliation_string":"the Department of Medicine, Tulane University School of Medicine, and Charty Hospital of Louisiana, New Orleans, La","institution_ids":["https://openalex.org/I114832834"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110008742","display_name":"Paul J. Murison","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I114832834","display_name":"Tulane University","ror":"https://ror.org/04vmvtb21","country_code":"US","type":"education","lineage":["https://openalex.org/I114832834"]},{"id":"https://openalex.org/I2799767083","display_name":"Ochsner Medical Center","ror":"https://ror.org/0290qyp66","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1336053918","https://openalex.org/I2799767083"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Paul J. Murison","raw_affiliation_strings":["Endocrine Research Laboratory of the Alton Ochsner Medical Foundation; the Department of Medicine, Tulane University School of Medicine, and Charty Hospital of Louisiana, New Orleans, La","Endocrine Research Laboratory of the Alton Ochsner Medical Foundation","the Department of Medicine, Tulane University School of Medicine, and Charty Hospital of Louisiana, New Orleans, La"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Endocrine Research Laboratory of the Alton Ochsner Medical Foundation; the Department of Medicine, Tulane University School of Medicine, and Charty Hospital of Louisiana, New Orleans, La","institution_ids":["https://openalex.org/I114832834","https://openalex.org/I2799767083"]},{"raw_affiliation_string":"Endocrine Research Laboratory of the Alton Ochsner Medical Foundation","institution_ids":["https://openalex.org/I2799767083"]},{"raw_affiliation_string":"the Department of Medicine, Tulane University School of Medicine, and Charty Hospital of Louisiana, New Orleans, La","institution_ids":["https://openalex.org/I114832834"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5017643954","display_name":"Joseph V. Schlosser","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I114832834","display_name":"Tulane University","ror":"https://ror.org/04vmvtb21","country_code":"US","type":"education","lineage":["https://openalex.org/I114832834"]},{"id":"https://openalex.org/I2799767083","display_name":"Ochsner Medical Center","ror":"https://ror.org/0290qyp66","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1336053918","https://openalex.org/I2799767083"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Joseph V. Schlosser","raw_affiliation_strings":["Endocrine Research Laboratory of the Alton Ochsner Medical Foundation; the Department of Medicine, Tulane University School of Medicine, and Charty Hospital of Louisiana, New Orleans, La","Endocrine Research Laboratory of the Alton Ochsner Medical Foundation","the Department of Medicine, Tulane University School of Medicine, and Charty Hospital of Louisiana, New Orleans, La"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Endocrine Research Laboratory of the Alton Ochsner Medical Foundation; the Department of Medicine, Tulane University School of Medicine, and Charty Hospital of Louisiana, New Orleans, La","institution_ids":["https://openalex.org/I114832834","https://openalex.org/I2799767083"]},{"raw_affiliation_string":"Endocrine Research Laboratory of the Alton Ochsner Medical Foundation","institution_ids":["https://openalex.org/I2799767083"]},{"raw_affiliation_string":"the Department of Medicine, Tulane University School of Medicine, and Charty Hospital of Louisiana, New Orleans, La","institution_ids":["https://openalex.org/I114832834"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":4790,"currency":"USD","value_usd":4790},"apc_paid":null,"fwci":3.4407,"has_fulltext":true,"cited_by_count":20,"citation_normalized_percentile":{"value":0.92098765,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":93},"biblio":{"volume":"11","issue":"6","first_page":"1187","last_page":"1189"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10756","display_name":"Estrogen and related hormone effects","score":0.7900000214576721,"subfield":{"id":"https://openalex.org/subfields/1310","display_name":"Endocrinology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10756","display_name":"Estrogen and related hormone effects","score":0.7900000214576721,"subfield":{"id":"https://openalex.org/subfields/1310","display_name":"Endocrinology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10183","display_name":"Breast Cancer Treatment Studies","score":0.17440000176429749,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10543","display_name":"Prostate Cancer Treatment and Research","score":0.015799999237060547,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/fluoxymesterone","display_name":"fluoxymesterone","score":0.9539999961853027},{"id":"https://openalex.org/keywords/androgenic-steroids","display_name":"androgenic steroids","score":0.6940000057220459},{"id":"https://openalex.org/keywords/metastatic-breast-cancer","display_name":"metastatic breast cancer","score":0.9110000133514404},{"id":"https://openalex.org/keywords/hormone-therapy","display_name":"hormone therapy","score":0.8199999928474426},{"id":"https://openalex.org/keywords/11beta-hydroxylation","display_name":"11\u03b2-hydroxylation","score":0.6890000104904175},{"id":"https://openalex.org/keywords/methyltestosterone","display_name":"methyltestosterone","score":0.6669999957084656},{"id":"https://openalex.org/keywords/testosterone","display_name":"testosterone","score":0.41999998688697815},{"id":"https://openalex.org/keywords/urinary-excretion","display_name":"urinary excretion","score":0.4440000057220459},{"id":"https://openalex.org/keywords/clinical-course","display_name":"clinical course","score":0.847000002861023}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.7304080128669739},{"id":"https://openalex.org/C46699223","wikidata":"https://www.wikidata.org/wiki/Q11078","display_name":"Endocrine system","level":3,"score":0.4596310555934906},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.3712141215801239},{"id":"https://openalex.org/C512399662","wikidata":"https://www.wikidata.org/wiki/Q3505712","display_name":"Family medicine","level":1,"score":0.33955127000808716},{"id":"https://openalex.org/C71315377","wikidata":"https://www.wikidata.org/wiki/Q11364","display_name":"Hormone","level":2,"score":0.330055832862854}],"mesh":[{"descriptor_ui":"D001940","descriptor_name":"Breast","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D001943","descriptor_name":"Breast Neoplasms","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":true},{"descriptor_ui":"D005438","descriptor_name":"Fludrocortisone","qualifier_ui":"Q000031","qualifier_name":"analogs & derivatives","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1002/1097-0142(195811/12)11:6<1187::aid-cncr2820110613>3.0.co;2-r","doi":"https://doi.org/10.1002/1097-0142(195811/12)11:6<1187::aid-cncr2820110613>3.0.co;2-r","is_oa":true,"landing_page_url":"https://doi.org/10.1002/1097-0142(195811/12)11:6<1187::aid-cncr2820110613>3.0.co;2-r","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/1097-0142%28195811/12%2911%3A6%3C1187%3A%3AAID-CNCR2820110613%3E3.0.CO%3B2-R","source":{"id":"https://openalex.org/S126033908","display_name":"Cancer","issn_l":"0008-543X","issn":["0008-543X","1045-7410","1097-0142"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cancer","raw_type":"journal-article"},{"id":"pmid:13608419","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/13608419","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cancer","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.1002/1097-0142(195811/12)11:6<1187::aid-cncr2820110613>3.0.co;2-r","doi":"https://doi.org/10.1002/1097-0142(195811/12)11:6<1187::aid-cncr2820110613>3.0.co;2-r","is_oa":true,"landing_page_url":"https://doi.org/10.1002/1097-0142(195811/12)11:6<1187::aid-cncr2820110613>3.0.co;2-r","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/1097-0142%28195811/12%2911%3A6%3C1187%3A%3AAID-CNCR2820110613%3E3.0.CO%3B2-R","source":{"id":"https://openalex.org/S126033908","display_name":"Cancer","issn_l":"0008-543X","issn":["0008-543X","1045-7410","1097-0142"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cancer","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.9763000011444092,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W1970758387.pdf","grobid_xml":"https://content.openalex.org/works/W1970758387.grobid-xml"},"referenced_works_count":5,"referenced_works":["https://openalex.org/W2041312213","https://openalex.org/W2047461251","https://openalex.org/W2071558340","https://openalex.org/W2084036942","https://openalex.org/W4245120456"],"related_works":["https://openalex.org/W2017838685","https://openalex.org/W1979735563","https://openalex.org/W2075401647","https://openalex.org/W2011254773","https://openalex.org/W2050133222","https://openalex.org/W2039777817","https://openalex.org/W2003271123","https://openalex.org/W1996714996","https://openalex.org/W2034260535","https://openalex.org/W1964856231"],"abstract_inverted_index":{"HE":[0],"ANDROGENIC":[1],"steroids":[2],"most":[3],"effective":[4],"in":[5,65,88],"T":[6],"the":[7,20,59,76],"treatment":[8],"of":[9,54,61,78,82],"metastatic":[10],"breast":[11,51],"cancer":[12],"have":[13,24],"all":[14],"been":[15,25],"potent":[16,22,32],"androgens.T":[17],"o":[18],"date,":[19],"less":[21,26],"androgens":[23],"effective.3~4Hence,":[27],"when":[28,71],"an":[29,62,86],"androgen":[30],"more":[31],"than":[33],"testosterone":[34,66],"or":[35],"methyltestosterone":[36],"became":[37],"available":[38],"it":[39,45,84],"was":[40],"thought":[41],"important":[42],"to":[43],"test":[44],"immediately":[46],"for":[47],"effectiveness":[48],"against":[49],"advanced":[50],"cancer.It":[52],"is":[53,73],"great":[55],"interest":[56],"that":[57],"although":[58],"introduction":[60,77],"11shydroxyl":[63],"group":[64,81],"reduces":[67],"its":[68],"androgenic":[69,90],"potency,":[70],"this":[72],"coupled":[74],"with":[75],"a":[79],"9a-fluoro":[80],"methyltestosterone,":[83],"produces":[85],"increase":[87],"oral":[89],"potency.":[91]},"counts_by_year":[{"year":2016,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}