{"id":"https://openalex.org/W197069747","doi":"https://doi.org/10.1007/978-1-60761-627-6_29","title":"Cancer Prevention with Berries: Role of Anthocyanins","display_name":"Cancer Prevention with Berries: Role of Anthocyanins","publication_year":2010,"publication_date":"2010-01-01","ids":{"openalex":"https://openalex.org/W197069747","doi":"https://doi.org/10.1007/978-1-60761-627-6_29","mag":"197069747"},"language":"en","primary_location":{"id":"doi:10.1007/978-1-60761-627-6_29","doi":"https://doi.org/10.1007/978-1-60761-627-6_29","is_oa":false,"landing_page_url":"https://doi.org/10.1007/978-1-60761-627-6_29","pdf_url":null,"source":{"id":"https://openalex.org/S4306463399","display_name":"Humana Press eBooks","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310315801","host_organization_name":"Humana Press","host_organization_lineage":["https://openalex.org/P4310315801","https://openalex.org/P4310319900"],"host_organization_lineage_names":["Humana Press","Springer Science+Business Media"],"type":"ebook platform"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioactive Compounds and Cancer","raw_type":"book-chapter"},"volume":{"id":"https://openalex.org/W2499932336","display_name":"Bioactive Compounds and Cancer"},"type":"book-chapter","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5032442574","display_name":"Gary D. Stoner","orcid":"https://orcid.org/0000-0002-7888-5609","observed_orcids":["https://orcid.org/0000-0002-7888-5609"]},"institutions":[{"id":"https://openalex.org/I2802841970","display_name":"The Ohio State University Wexner Medical Center","ror":"https://ror.org/00c01js51","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2802841970"]},{"id":"https://openalex.org/I52357470","display_name":"The Ohio State University","ror":"https://ror.org/00rs6vg23","country_code":"US","type":"education","lineage":["https://openalex.org/I52357470"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Gary D. Stoner","raw_affiliation_strings":["Comprehensive Cancer Center, The Ohio State University College of Medicine, Columbus, OH, USA","Division of Hematology and Oncology, Department of Internal Medicine, Innovation Centre, The Ohio State University College of Medicine, Columbus, OH, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Comprehensive Cancer Center, The Ohio State University College of Medicine, Columbus, OH, USA","institution_ids":["https://openalex.org/I52357470"]},{"raw_affiliation_string":"Division of Hematology and Oncology, Department of Internal Medicine, Innovation Centre, The Ohio State University College of Medicine, Columbus, OH, USA","institution_ids":["https://openalex.org/I2802841970","https://openalex.org/I52357470"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5075856826","display_name":"Li\u2010Shu Wang","orcid":"https://orcid.org/0000-0002-6500-6943","observed_orcids":["https://orcid.org/0000-0002-6500-6943"]},"institutions":[{"id":"https://openalex.org/I52357470","display_name":"The Ohio State University","ror":"https://ror.org/00rs6vg23","country_code":"US","type":"education","lineage":["https://openalex.org/I52357470"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Li-Shu Wang","raw_affiliation_strings":["Comprehensive Cancer Center, The Ohio State University College of Medicine, Columbus, OH, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Comprehensive Cancer Center, The Ohio State University College of Medicine, Columbus, OH, USA","institution_ids":["https://openalex.org/I52357470"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5034925980","display_name":"Christine L. Sardo","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I52357470","display_name":"The Ohio State University","ror":"https://ror.org/00rs6vg23","country_code":"US","type":"education","lineage":["https://openalex.org/I52357470"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Christine Sardo","raw_affiliation_strings":["Comprehensive Cancer Center, The Ohio State University College of Medicine, Columbus, OH, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Comprehensive Cancer Center, The Ohio State University College of Medicine, Columbus, OH, USA","institution_ids":["https://openalex.org/I52357470"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5060346788","display_name":"Nancy N. Zikri","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I52357470","display_name":"The Ohio State University","ror":"https://ror.org/00rs6vg23","country_code":"US","type":"education","lineage":["https://openalex.org/I52357470"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Nancy Zikri","raw_affiliation_strings":["Department of Cardiovascular Medicine, The Ohio State University College of Medicine, Columbus, OH, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cardiovascular Medicine, The Ohio State University College of Medicine, Columbus, OH, USA","institution_ids":["https://openalex.org/I52357470"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5033402104","display_name":"Stephen S. Hecht","orcid":"https://orcid.org/0000-0001-7228-1356","observed_orcids":["https://orcid.org/0000-0001-7228-1356"]},"institutions":[{"id":"https://openalex.org/I130238516","display_name":"University of Minnesota","ror":"https://ror.org/017zqws13","country_code":"US","type":"education","lineage":["https://openalex.org/I130238516"]},{"id":"https://openalex.org/I4390039358","display_name":"Masonic Cancer Center","ror":"https://ror.org/05x083d20","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I130238516","https://openalex.org/I4390039358"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Stephen S. Hecht","raw_affiliation_strings":["Masonic Cancer Center, University of Minnesota, Minneapolis, MN, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Masonic Cancer Center, University of Minnesota, Minneapolis, MN, USA","institution_ids":["https://openalex.org/I130238516","https://openalex.org/I4390039358"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5086348397","display_name":"Susan R. Mallery","orcid":"https://orcid.org/0000-0003-3122-0244","observed_orcids":["https://orcid.org/0000-0003-3122-0244"]},"institutions":[{"id":"https://openalex.org/I52357470","display_name":"The Ohio State University","ror":"https://ror.org/00rs6vg23","country_code":"US","type":"education","lineage":["https://openalex.org/I52357470"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Susan R. Mallery","raw_affiliation_strings":["Division of Oral Surgery, Pathology and Anesthesiology, College of Dentistry, The Ohio State University, Columbus, OH, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Oral Surgery, Pathology and Anesthesiology, College of Dentistry, The Ohio State University, Columbus, OH, USA","institution_ids":["https://openalex.org/I52357470"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":3.101,"has_fulltext":false,"cited_by_count":9,"citation_normalized_percentile":{"value":0.88888889,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":95},"biblio":{"volume":null,"issue":null,"first_page":"703","last_page":"723"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10035","display_name":"Phytochemicals and Antioxidant Activities","score":0.9814000129699707,"subfield":{"id":"https://openalex.org/subfields/2704","display_name":"Biochemistry (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10035","display_name":"Phytochemicals and Antioxidant Activities","score":0.9814000129699707,"subfield":{"id":"https://openalex.org/subfields/2704","display_name":"Biochemistry (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12638","display_name":"Pomegranate: compositions and health benefits","score":0.0066999997943639755,"subfield":{"id":"https://openalex.org/subfields/2916","display_name":"Nutrition and Dietetics"},"field":{"id":"https://openalex.org/fields/29","display_name":"Nursing"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12605","display_name":"Berry genetics and cultivation research","score":0.003700000001117587,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/berries","display_name":"berries","score":0.9319999814033508},{"id":"https://openalex.org/keywords/anthocyanins","display_name":"anthocyanins","score":0.996999979019165},{"id":"https://openalex.org/keywords/chemoprevention","display_name":"chemoprevention","score":0.9110000133514404},{"id":"https://openalex.org/keywords/flavonoids","display_name":"flavonoids","score":0.9229999780654907},{"id":"https://openalex.org/keywords/esophageal-cancer","display_name":"esophageal cancer","score":0.8199999928474426},{"id":"https://openalex.org/keywords/colon-cancer","display_name":"colon cancer","score":0.9049999713897705},{"id":"https://openalex.org/keywords/oral-epithelial-dysplasia","display_name":"oral dysplasia","score":0.8420000076293945},{"id":"https://openalex.org/keywords/black-raspberry","display_name":"black raspberry","score":0.7850000262260437},{"id":"https://openalex.org/keywords/loss-of-heterozygosity","display_name":"loss of heterozygosity","score":0.968999981880188},{"id":"https://openalex.org/keywords/ki67-cell-proliferation","display_name":"Ki-67 cell proliferation","score":0.9390000104904175},{"id":"https://openalex.org/keywords/angiogenesis-inhibition","display_name":"angiogenesis inhibition","score":0.8450000286102295},{"id":"https://openalex.org/keywords/apoptosis","display_name":"apoptosis","score":0.7549999952316284},{"id":"https://openalex.org/keywords/gene-expression","display_name":"gene expression","score":0.5709999799728394},{"id":"https://openalex.org/keywords/dietary-phytochemicals","display_name":"dietary phytochemicals","score":0.6650000214576721}],"concepts":[{"id":"https://openalex.org/C2776034682","wikidata":"https://www.wikidata.org/wiki/Q13184","display_name":"Berry","level":2,"score":0.7872133851051331},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.4652726352214813},{"id":"https://openalex.org/C62112901","wikidata":"https://www.wikidata.org/wiki/Q189159","display_name":"Cell growth","level":2,"score":0.4594581425189972},{"id":"https://openalex.org/C2780394083","wikidata":"https://www.wikidata.org/wiki/Q539568","display_name":"Angiogenesis","level":2,"score":0.4513421058654785},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.4319019317626953},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.4290004074573517},{"id":"https://openalex.org/C526805850","wikidata":"https://www.wikidata.org/wiki/Q188874","display_name":"Colorectal cancer","level":3,"score":0.4212779104709625},{"id":"https://openalex.org/C555283112","wikidata":"https://www.wikidata.org/wiki/Q1637543","display_name":"Carcinogenesis","level":3,"score":0.41670462489128113},{"id":"https://openalex.org/C31903555","wikidata":"https://www.wikidata.org/wiki/Q1637030","display_name":"Food science","level":1,"score":0.3720216155052185},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.3578190803527832},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3348926901817322},{"id":"https://openalex.org/C59822182","wikidata":"https://www.wikidata.org/wiki/Q441","display_name":"Botany","level":1,"score":0.2810530364513397},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.27584731578826904},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.22687312960624695}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1007/978-1-60761-627-6_29","doi":"https://doi.org/10.1007/978-1-60761-627-6_29","is_oa":false,"landing_page_url":"https://doi.org/10.1007/978-1-60761-627-6_29","pdf_url":null,"source":{"id":"https://openalex.org/S4306463399","display_name":"Humana Press eBooks","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310315801","host_organization_name":"Humana Press","host_organization_lineage":["https://openalex.org/P4310315801","https://openalex.org/P4310319900"],"host_organization_lineage_names":["Humana Press","Springer Science+Business Media"],"type":"ebook platform"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioactive Compounds and Cancer","raw_type":"book-chapter"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.9922999739646912,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":45,"referenced_works":["https://openalex.org/W106804345","https://openalex.org/W199331381","https://openalex.org/W1987468097","https://openalex.org/W1988369809","https://openalex.org/W1989696722","https://openalex.org/W1994377495","https://openalex.org/W1997787718","https://openalex.org/W1998213008","https://openalex.org/W1998888158","https://openalex.org/W2004426696","https://openalex.org/W2017645793","https://openalex.org/W2021602836","https://openalex.org/W2022045860","https://openalex.org/W2022855758","https://openalex.org/W2027243245","https://openalex.org/W2028610535","https://openalex.org/W2030948649","https://openalex.org/W2031188227","https://openalex.org/W2032681327","https://openalex.org/W2032847540","https://openalex.org/W2039745096","https://openalex.org/W2059022882","https://openalex.org/W2065815891","https://openalex.org/W2068954221","https://openalex.org/W2080029337","https://openalex.org/W2088561516","https://openalex.org/W2094947208","https://openalex.org/W2101072227","https://openalex.org/W2102681375","https://openalex.org/W2108337707","https://openalex.org/W2122180872","https://openalex.org/W2122765939","https://openalex.org/W2129049219","https://openalex.org/W2131536959","https://openalex.org/W2143847534","https://openalex.org/W2147085467","https://openalex.org/W2149664901","https://openalex.org/W2156631697","https://openalex.org/W2158564334","https://openalex.org/W2160716044","https://openalex.org/W2164363934","https://openalex.org/W2167451051","https://openalex.org/W2167674333","https://openalex.org/W2169739237","https://openalex.org/W3023045369"],"related_works":["https://openalex.org/W2533328417","https://openalex.org/W2137792238","https://openalex.org/W2114354408","https://openalex.org/W2299446148","https://openalex.org/W2088561516","https://openalex.org/W2260702953","https://openalex.org/W2018329751","https://openalex.org/W4253382009","https://openalex.org/W2185351165","https://openalex.org/W2322957374"],"abstract_inverted_index":{"1.":[0],"Berries":[1,81],"have":[2],"been":[3,41],"part":[4,258],"of":[5,17,59,91,118,129,141,149,161,173,175,181,185,194,219,259,273,276],"the":[6,51,64,72,74,88,116,138,182,201,260,270],"human":[7],"diet":[8],"for":[9,158,196],"many":[10],"centuries.":[11],"They":[12],"are":[13,71,229],"a":[14,112,154,159,166,192],"rich":[15],"source":[16],"known":[18],"chemopreventive":[19],"agents":[20],"including":[21],"provitamin":[22],"A":[23],"carotenoids,":[24],"C,":[25],"E,":[26],"and":[27,30,33,36,56,96,98,103,171,263],"folate,":[28],"calcium":[29],"selenium,":[31],"simple":[32],"complex":[34],"phenols,":[35],"phytosterols.":[37],"2.":[38],"It":[39,250],"has":[40],"found":[42],"that":[43,63,109,236,255,264],"freeze-dried":[44],"berries":[45,70,110,130,220,256],"can":[46],"inhibit":[47,84],"cancer":[48,133,213,222],"development":[49,223],"in":[50,69,78,165,168,178,191,206,227,245,248,265],"esophagus,":[52],"colon,":[53],"oral":[54,150],"cavity,":[55],"mammary":[57],"gland":[58],"rodents.":[60],"Studies":[61],"suggest":[62,254],"most":[65,75],"active":[66],"inhibitory":[67],"compounds":[68,143],"anthocyanins,":[73],"abundant":[76],"flavonoids":[77],"berries.":[79],"3.":[80],"function":[82],"to":[83,131,137,240,253],"carcinogenesis":[85],"by":[86],"reducing":[87],"growth":[89],"rate":[90],"premalignant":[92],"cells,":[93],"inhibiting":[94],"angiogenesis":[95],"inflammation,":[97],"stimulating":[99],"apoptosis,":[100],"cell":[101,104,203],"differentiation,":[102],"adhesion.":[105],"Molecular":[106],"studies":[107],"indicate":[108],"exhibit":[111],"genome-wide":[113],"effect":[114],"on":[115,221],"expression":[117],"genes":[119],"associated":[120],"with":[121,153],"these":[122],"different":[123],"cellular":[124],"functions.":[125],"4.":[126],"The":[127,216],"ability":[128],"prevent":[132],"is":[134,233],"likely":[135],"due":[136],"localized":[139],"absorption":[140],"berry":[142,237,277],"into":[144],"target":[145],"tissues.":[146],"Topical":[147],"treatment":[148],"dysplastic":[151],"lesions":[152],"black":[155,186],"raspberry":[156,187],"gel":[157],"period":[160],"6":[162],"weeks":[163,199],"resulted":[164],"reduction":[167],"histological":[169],"grade":[170],"restoration":[172],"loss":[174],"heterozygosity":[176],"(LOH)":[177],"about":[179],"50%":[180],"lesions.":[183],"Consumption":[184],"powder":[188,278],"(60":[189],"g/day)":[190],"slurry":[193],"water":[195],"only":[197],"2\u20134":[198],"reduced":[200],"Ki-67":[202],"proliferation":[204],"index":[205],"colon":[207],"tumors":[208],"taken":[209],"at":[210,224,267],"surgery":[211],"from":[212],"patients.":[214],"5.":[215],"protective":[217],"effects":[218,243],"specific":[225],"sites":[226],"animals":[228,246],"impressive;":[230],"however,":[231],"there":[232],"little":[234],"evidence":[235],"consumption":[238,272],"leads":[239],"significant":[241],"side":[242],"either":[244],"or":[247],"humans.":[249],"seems":[251],"reasonable":[252],"be":[257],"daily":[261,271],"diet,":[262],"individuals":[266],"high":[268],"risk,":[269],"several":[274],"grams":[275],"could":[279],"well":[280],"elicit":[281],"protection.":[282]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":1},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":2},{"year":2019,"cited_by_count":1},{"year":2012,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}