{"id":"https://openalex.org/W1970654518","doi":"https://doi.org/10.1038/296668a0","title":"Structural homology of a macrophage differentiation antigen and an antigen involved in T-cell-mediated killing","display_name":"Structural homology of a macrophage differentiation antigen and an antigen involved in T-cell-mediated killing","publication_year":1982,"publication_date":"1982-04-01","ids":{"openalex":"https://openalex.org/W1970654518","doi":"https://doi.org/10.1038/296668a0","mag":"1970654518","pmid":"https://pubmed.ncbi.nlm.nih.gov/6175907"},"language":"en","primary_location":{"id":"doi:10.1038/296668a0","doi":"https://doi.org/10.1038/296668a0","is_oa":false,"landing_page_url":"https://doi.org/10.1038/296668a0","pdf_url":null,"source":{"id":"https://openalex.org/S137773608","display_name":"Nature","issn_l":"0028-0836","issn":["0028-0836","1476-4687"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-a","doyens","erih-plus","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nature","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5091071411","display_name":"K. K\u00fcrzinger","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Konrad K\u00fcrzinger","raw_affiliation_strings":["Laboratory of Membrane Immunochemistry, Sidney Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts, 02115, USA","Laboratory of Membrane Immunochemistry, Sidney Farber Cancer Institute, Harvard Medical School, Boston, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory of Membrane Immunochemistry, Sidney Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts, 02115, USA","institution_ids":["https://openalex.org/I136199984"]},{"raw_affiliation_string":"Laboratory of Membrane Immunochemistry, Sidney Farber Cancer Institute, Harvard Medical School, Boston, USA","institution_ids":["https://openalex.org/I136199984"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5084437187","display_name":"M K Ho","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"May-Kin Ho","raw_affiliation_strings":["Laboratory of Membrane Immunochemistry, Sidney Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts, 02115, USA","Laboratory of Membrane Immunochemistry, Sidney Farber Cancer Institute, Harvard Medical School, Boston, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory of Membrane Immunochemistry, Sidney Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts, 02115, USA","institution_ids":["https://openalex.org/I136199984"]},{"raw_affiliation_string":"Laboratory of Membrane Immunochemistry, Sidney Farber Cancer Institute, Harvard Medical School, Boston, USA","institution_ids":["https://openalex.org/I136199984"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5003615852","display_name":"Timothy A. Springer","orcid":"https://orcid.org/0000-0001-6627-2904","observed_orcids":["https://orcid.org/0000-0001-6627-2904"]},"institutions":[{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Timothy A. Springer","raw_affiliation_strings":["Laboratory of Membrane Immunochemistry, Sidney Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts, 02115, USA","Laboratory of Membrane Immunochemistry, Sidney Farber Cancer Institute, Harvard Medical School, Boston, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory of Membrane Immunochemistry, Sidney Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts, 02115, USA","institution_ids":["https://openalex.org/I136199984"]},{"raw_affiliation_string":"Laboratory of Membrane Immunochemistry, Sidney Farber Cancer Institute, Harvard Medical School, Boston, USA","institution_ids":["https://openalex.org/I136199984"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I136199984"],"apc_list":{"value":12690,"currency":"USD","value_usd":12690},"apc_paid":null,"fwci":12.22,"has_fulltext":false,"cited_by_count":92,"citation_normalized_percentile":{"value":0.98816029,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":96},"biblio":{"volume":"296","issue":"5858","first_page":"668","last_page":"670"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10831","display_name":"Cell Adhesion Molecules Research","score":0.9976000189781189,"subfield":{"id":"https://openalex.org/subfields/2723","display_name":"Immunology and Allergy"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10831","display_name":"Cell Adhesion Molecules Research","score":0.9976000189781189,"subfield":{"id":"https://openalex.org/subfields/2723","display_name":"Immunology and Allergy"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10031","display_name":"T-cell and B-cell Immunology","score":0.00139999995008111,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T13326","display_name":"Biochemical and Structural Characterization","score":0.0003000000142492354,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/mac-1","display_name":"Mac-1","score":0.9959999918937683},{"id":"https://openalex.org/keywords/lfa-1","display_name":"LFA-1","score":0.9929999709129333},{"id":"https://openalex.org/keywords/t-cell-mediated-killing","display_name":"T cell-mediated killing","score":0.8460000157356262},{"id":"https://openalex.org/keywords/structural-homology","display_name":"structural homology","score":0.6629999876022339},{"id":"https://openalex.org/keywords/beta-subunit","display_name":"beta subunit","score":0.5550000071525574},{"id":"https://openalex.org/keywords/alpha-subunit","display_name":"alpha subunit","score":0.6809999942779541},{"id":"https://openalex.org/keywords/tryptic-peptide-mapping","display_name":"tryptic peptide mapping","score":0.8349999785423279},{"id":"https://openalex.org/keywords/epitopes","display_name":"antigenic determinants","score":0.8289999961853027},{"id":"https://openalex.org/keywords/leukocyte-adhesion-molecules","display_name":"leukocyte adhesion molecules","score":0.6240000128746033},{"id":"https://openalex.org/keywords/natural-killer-cells","display_name":"natural killer cells","score":0.7409999966621399},{"id":"https://openalex.org/keywords/lymphocytes","display_name":"lymphocytes","score":0.3179999887943268}],"concepts":[{"id":"https://openalex.org/C147483822","wikidata":"https://www.wikidata.org/wiki/Q103537","display_name":"Antigen","level":2,"score":0.7733698487281799},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.5911288857460022},{"id":"https://openalex.org/C956191","wikidata":"https://www.wikidata.org/wiki/Q930144","display_name":"Polyclonal antibodies","level":3,"score":0.582472026348114},{"id":"https://openalex.org/C542903549","wikidata":"https://www.wikidata.org/wiki/Q422248","display_name":"Monoclonal antibody","level":3,"score":0.5590455532073975},{"id":"https://openalex.org/C153911025","wikidata":"https://www.wikidata.org/wiki/Q7202","display_name":"Molecular biology","level":1,"score":0.5524618625640869},{"id":"https://openalex.org/C195616568","wikidata":"https://www.wikidata.org/wiki/Q128711","display_name":"Epitope","level":3,"score":0.5279081463813782},{"id":"https://openalex.org/C91523082","wikidata":"https://www.wikidata.org/wiki/Q420496","display_name":"Antiserum","level":3,"score":0.5196086764335632},{"id":"https://openalex.org/C159654299","wikidata":"https://www.wikidata.org/wiki/Q79460","display_name":"Antibody","level":2,"score":0.41319894790649414},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.25945645570755005}],"mesh":[{"descriptor_ui":"D000939","descriptor_name":"Epitopes","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000945","descriptor_name":"Antigens, Differentiation, T-Lymphocyte","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000950","descriptor_name":"Antigens, Ly","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D000954","descriptor_name":"Antigens, Surface","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":true},{"descriptor_ui":"D003429","descriptor_name":"Cross Reactions","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003602","descriptor_name":"Cytotoxicity, Immunologic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D008264","descriptor_name":"Macrophages","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D008970","descriptor_name":"Molecular Weight","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010446","descriptor_name":"Peptide Fragments","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D013601","descriptor_name":"T-Lymphocytes","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D046911","descriptor_name":"Macromolecular Substances","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1038/296668a0","doi":"https://doi.org/10.1038/296668a0","is_oa":false,"landing_page_url":"https://doi.org/10.1038/296668a0","pdf_url":null,"source":{"id":"https://openalex.org/S137773608","display_name":"Nature","issn_l":"0028-0836","issn":["0028-0836","1476-4687"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-a","doyens","erih-plus","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nature","raw_type":"journal-article"},{"id":"pmid:6175907","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/6175907","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nature","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.504800021648407,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":11,"referenced_works":["https://openalex.org/W366708227","https://openalex.org/W628974502","https://openalex.org/W1515213049","https://openalex.org/W1530566145","https://openalex.org/W1659855818","https://openalex.org/W1893651774","https://openalex.org/W2023318533","https://openalex.org/W2028525401","https://openalex.org/W2087655494","https://openalex.org/W2102386308","https://openalex.org/W2310464721"],"related_works":["https://openalex.org/W1585833237","https://openalex.org/W7096297604","https://openalex.org/W2118531513","https://openalex.org/W1912884088","https://openalex.org/W935993939","https://openalex.org/W48516434","https://openalex.org/W2140799426","https://openalex.org/W2146756090","https://openalex.org/W1526152795","https://openalex.org/W1977277445"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":3},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":1}],"updated_date":"2026-11-03T10:50:19.383937","created_date":"2016-06-24T00:00:00"}