{"id":"https://openalex.org/W1970650565","doi":"https://doi.org/10.1002/mrd.1080420312","title":"LL95 monoclonal antibody mimics functional effects of ZP3 on mouse sperm: Evidence that the antigen recognized is not hexokinase","display_name":"LL95 monoclonal antibody mimics functional effects of ZP3 on mouse sperm: Evidence that the antigen recognized is not hexokinase","publication_year":1995,"publication_date":"1995-11-01","ids":{"openalex":"https://openalex.org/W1970650565","doi":"https://doi.org/10.1002/mrd.1080420312","mag":"1970650565","pmid":"https://pubmed.ncbi.nlm.nih.gov/8579849"},"language":"en","primary_location":{"id":"doi:10.1002/mrd.1080420312","doi":"https://doi.org/10.1002/mrd.1080420312","is_oa":false,"landing_page_url":"https://doi.org/10.1002/mrd.1080420312","pdf_url":null,"source":{"id":"https://openalex.org/S125242520","display_name":"Molecular Reproduction and Development","issn_l":"1040-452X","issn":["1040-452X","1098-2795"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Molecular Reproduction and Development","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5029827243","display_name":"Lisette Leyton","orcid":"https://orcid.org/0000-0001-9690-9638","observed_orcids":["https://orcid.org/0000-0001-9690-9638"]},"institutions":[{"id":"https://openalex.org/I170897317","display_name":"Duke University","ror":"https://ror.org/00py81415","country_code":"US","type":"education","lineage":["https://openalex.org/I170897317"]},{"id":"https://openalex.org/I4210126298","display_name":"Duke Medical Center","ror":"https://ror.org/03njmea73","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210126298","https://openalex.org/I4210144876"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Lisette Leyton","raw_affiliation_strings":["Department of Obstetrics, Duke University Medical Center, Durham, NC 27710, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Obstetrics, Duke University Medical Center, Durham, NC 27710, USA","institution_ids":["https://openalex.org/I170897317","https://openalex.org/I4210126298"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5010522756","display_name":"Claudia Nora Tomes","orcid":"https://orcid.org/0000-0002-3376-6868","observed_orcids":["https://orcid.org/0000-0002-3376-6868"]},"institutions":[{"id":"https://openalex.org/I170897317","display_name":"Duke University","ror":"https://ror.org/00py81415","country_code":"US","type":"education","lineage":["https://openalex.org/I170897317"]},{"id":"https://openalex.org/I4210126298","display_name":"Duke Medical Center","ror":"https://ror.org/03njmea73","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210126298","https://openalex.org/I4210144876"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Claudia Tomes","raw_affiliation_strings":["Departments of Obstetrics and Gynecology and Cell Biology, Duke University Medical Center, Durham, North Carolina"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departments of Obstetrics and Gynecology and Cell Biology, Duke University Medical Center, Durham, North Carolina","institution_ids":["https://openalex.org/I170897317","https://openalex.org/I4210126298"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5065093786","display_name":"Patricia M. Saling","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I170897317","display_name":"Duke University","ror":"https://ror.org/00py81415","country_code":"US","type":"education","lineage":["https://openalex.org/I170897317"]},{"id":"https://openalex.org/I4210126298","display_name":"Duke Medical Center","ror":"https://ror.org/03njmea73","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210126298","https://openalex.org/I4210144876"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Patricia Saling","raw_affiliation_strings":["Departments of Obstetrics and Gynecology and Cell Biology, Duke University Medical Center, Durham, North Carolina"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departments of Obstetrics and Gynecology and Cell Biology, Duke University Medical Center, Durham, North Carolina","institution_ids":["https://openalex.org/I170897317","https://openalex.org/I4210126298"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5065093786"],"corresponding_institution_ids":["https://openalex.org/I170897317","https://openalex.org/I4210126298"],"apc_list":{"value":4260,"currency":"USD","value_usd":4260},"apc_paid":null,"fwci":4.1809,"has_fulltext":false,"cited_by_count":21,"citation_normalized_percentile":{"value":0.9358893,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":89,"max":94},"biblio":{"volume":"42","issue":"3","first_page":"347","last_page":"358"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10116","display_name":"Sperm and Testicular Function","score":0.9911999702453613,"subfield":{"id":"https://openalex.org/subfields/2743","display_name":"Reproductive Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10116","display_name":"Sperm and Testicular Function","score":0.9911999702453613,"subfield":{"id":"https://openalex.org/subfields/2743","display_name":"Reproductive Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10364","display_name":"Reproductive Biology and Fertility","score":0.003800000064074993,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11505","display_name":"Reproductive biology and impacts on aquatic species","score":0.0020000000949949026,"subfield":{"id":"https://openalex.org/subfields/1314","display_name":"Physiology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/zp3","display_name":"ZP3","score":0.7089999914169312},{"id":"https://openalex.org/keywords/zona-pellucida","display_name":"zona pellucida","score":0.8659999966621399},{"id":"https://openalex.org/keywords/sperm-receptor","display_name":"sperm receptor","score":0.6449999809265137},{"id":"https://openalex.org/keywords/acrosome-reaction","display_name":"acrosome reaction","score":0.8550000190734863},{"id":"https://openalex.org/keywords/sperm-zona-binding","display_name":"sperm-zona binding","score":0.7559999823570251},{"id":"https://openalex.org/keywords/receptor-oligomerization","display_name":"receptor oligomerization","score":0.7990000247955322},{"id":"https://openalex.org/keywords/tyrosine-phosphorylation","display_name":"tyrosine phosphorylation","score":0.8539999723434448},{"id":"https://openalex.org/keywords/hexokinase","display_name":"hexokinase","score":0.8109999895095825},{"id":"https://openalex.org/keywords/mouse-sperm","display_name":"mouse sperm","score":0.4950000047683716},{"id":"https://openalex.org/keywords/gamete-interaction","display_name":"gamete interaction","score":0.6660000085830688},{"id":"https://openalex.org/keywords/tyrosine-kinase-inhibitors","display_name":"tyrosine kinase inhibitors","score":0.6570000052452087},{"id":"https://openalex.org/keywords/crosslinking-agents","display_name":"crosslinking agents","score":0.41100001335144043}],"concepts":[{"id":"https://openalex.org/C2776010925","wikidata":"https://www.wikidata.org/wiki/Q219841","display_name":"Zona pellucida","level":4,"score":0.8894329071044922},{"id":"https://openalex.org/C2910492233","wikidata":"https://www.wikidata.org/wiki/Q219841","display_name":"Zona pellucida glycoprotein","level":5,"score":0.8721407651901245},{"id":"https://openalex.org/C2779995066","wikidata":"https://www.wikidata.org/wiki/Q163261","display_name":"Acrosome reaction","level":3,"score":0.8355485200881958},{"id":"https://openalex.org/C2781087480","wikidata":"https://www.wikidata.org/wiki/Q17145","display_name":"Sperm","level":2,"score":0.7188436985015869},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.6958053112030029},{"id":"https://openalex.org/C2777553839","wikidata":"https://www.wikidata.org/wiki/Q14330986","display_name":"Tyrosine phosphorylation","level":3,"score":0.5988360047340393},{"id":"https://openalex.org/C542903549","wikidata":"https://www.wikidata.org/wiki/Q422248","display_name":"Monoclonal antibody","level":3,"score":0.5402334332466125},{"id":"https://openalex.org/C153911025","wikidata":"https://www.wikidata.org/wiki/Q7202","display_name":"Molecular biology","level":1,"score":0.5098382830619812},{"id":"https://openalex.org/C2778252442","wikidata":"https://www.wikidata.org/wiki/Q421111","display_name":"Acrosome","level":3,"score":0.46689924597740173},{"id":"https://openalex.org/C2776165026","wikidata":"https://www.wikidata.org/wiki/Q188017","display_name":"Tyrosine","level":2,"score":0.4655711352825165},{"id":"https://openalex.org/C2779826832","wikidata":"https://www.wikidata.org/wiki/Q982914","display_name":"Hexokinase","level":4,"score":0.460924357175827},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.3880361020565033},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.38707226514816284},{"id":"https://openalex.org/C159654299","wikidata":"https://www.wikidata.org/wiki/Q79460","display_name":"Antibody","level":2,"score":0.3426959216594696},{"id":"https://openalex.org/C2776690073","wikidata":"https://www.wikidata.org/wiki/Q3246226","display_name":"Oocyte","level":3,"score":0.18474063277244568},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.16454583406448364},{"id":"https://openalex.org/C181199279","wikidata":"https://www.wikidata.org/wiki/Q8047","display_name":"Enzyme","level":2,"score":0.12569576501846313},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.07568415999412537},{"id":"https://openalex.org/C196843134","wikidata":"https://www.wikidata.org/wiki/Q33196","display_name":"Embryo","level":2,"score":0.0573846697807312},{"id":"https://openalex.org/C20251656","wikidata":"https://www.wikidata.org/wiki/Q162643","display_name":"Glycolysis","level":3,"score":0.0}],"mesh":[{"descriptor_ui":"D000072216","descriptor_name":"Zona Pellucida Glycoproteins","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000076202","descriptor_name":"c-Mer Tyrosine Kinase","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000177","descriptor_name":"Acrosome","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000911","descriptor_name":"Antibodies, Monoclonal","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D000941","descriptor_name":"Antigens","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D003432","descriptor_name":"Cross-Linking Reagents","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004527","descriptor_name":"Egg Proteins","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006593","descriptor_name":"Hexokinase","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D006593","descriptor_name":"Hexokinase","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008562","descriptor_name":"Membrane Glycoproteins","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D008807","descriptor_name":"Mice, Inbred BALB C","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010766","descriptor_name":"Phosphorylation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011518","descriptor_name":"Proto-Oncogene Proteins","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011956","descriptor_name":"Receptors, Cell Surface","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D013094","descriptor_name":"Spermatozoa","qualifier_ui":"Q000201","qualifier_name":"enzymology","is_major_topic":false},{"descriptor_ui":"D013094","descriptor_name":"Spermatozoa","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D020794","descriptor_name":"Receptor Protein-Tyrosine Kinases","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D020794","descriptor_name":"Receptor Protein-Tyrosine Kinases","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1002/mrd.1080420312","doi":"https://doi.org/10.1002/mrd.1080420312","is_oa":false,"landing_page_url":"https://doi.org/10.1002/mrd.1080420312","pdf_url":null,"source":{"id":"https://openalex.org/S125242520","display_name":"Molecular Reproduction and Development","issn_l":"1040-452X","issn":["1040-452X","1098-2795"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Molecular Reproduction and Development","raw_type":"journal-article"},{"id":"pmid:8579849","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/8579849","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Molecular reproduction and development","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[],"sustainable_development_goals_aurora":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G1869077546","display_name":null,"funder_award_id":"HD18201","funder_id":"https://openalex.org/F4320337611","funder_display_name":"Eunice Kennedy Shriver National Institute of Child Health and Human Development"},{"id":"https://openalex.org/G8650993521","display_name":"FUNCTION OF SPERM MEMBRANE PROTEINS IN FERTILIZATION","funder_award_id":"5r01hd018201-15","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"}],"funders":[{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337611","display_name":"Eunice Kennedy Shriver National Institute of Child Health and Human Development","ror":"https://ror.org/04byxyr05"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":48,"referenced_works":["https://openalex.org/W586595461","https://openalex.org/W1482108000","https://openalex.org/W1505531110","https://openalex.org/W1521897480","https://openalex.org/W1528378220","https://openalex.org/W1574013273","https://openalex.org/W1594700207","https://openalex.org/W1611793055","https://openalex.org/W1806357672","https://openalex.org/W1974298024","https://openalex.org/W1974489009","https://openalex.org/W1975319217","https://openalex.org/W1976821556","https://openalex.org/W1987063238","https://openalex.org/W1991745126","https://openalex.org/W1997021745","https://openalex.org/W1999352791","https://openalex.org/W2002713681","https://openalex.org/W2005668319","https://openalex.org/W2008084413","https://openalex.org/W2022488752","https://openalex.org/W2032359283","https://openalex.org/W2035622733","https://openalex.org/W2052428576","https://openalex.org/W2052865938","https://openalex.org/W2054168344","https://openalex.org/W2058128222","https://openalex.org/W2067978325","https://openalex.org/W2073551759","https://openalex.org/W2078032385","https://openalex.org/W2079723355","https://openalex.org/W2087604551","https://openalex.org/W2090383712","https://openalex.org/W2095122911","https://openalex.org/W2100837269","https://openalex.org/W2101108802","https://openalex.org/W2115823147","https://openalex.org/W2122048408","https://openalex.org/W2128056949","https://openalex.org/W2129434760","https://openalex.org/W2129841410","https://openalex.org/W2136807628","https://openalex.org/W2148984072","https://openalex.org/W2152517651","https://openalex.org/W2163298310","https://openalex.org/W2414551341","https://openalex.org/W3196205673","https://openalex.org/W4206302388"],"related_works":["https://openalex.org/W2035622733","https://openalex.org/W2163298310","https://openalex.org/W2392084187","https://openalex.org/W2022566886","https://openalex.org/W2067092088","https://openalex.org/W2082789073","https://openalex.org/W2085674561","https://openalex.org/W2005668319","https://openalex.org/W2129434760","https://openalex.org/W2086383950"],"abstract_inverted_index":{"In":[0],"the":[1,16,83,110,115,124,134,143,153,165,171,175,196,204,209],"mouse,":[2],"a":[3,12,27,127,192,217,260,312],"95":[4,22,60,65,135,210,237],"kD":[5,23,61,66,136,211,238,262],"sperm":[6,24,54,84,193,267,313],"protein":[7,25,67,212,263],"has":[8],"been":[9],"identified":[10],"as":[11],"putative":[13],"receptor":[14,88,160,194],"for":[15,94,187,195],"zona":[17,37,71,197],"pellucida":[18,38,72],"glycoprotein":[19],"ZP3.":[20,120],"The":[21,40,156],"is":[26,43,73,92,168,255,259,284],"tyrosine":[28,34,68,77],"kinase":[29,78],"substrate,":[30],"with":[31],"phosphorylation":[32,69],"on":[33,159,299],"stimulated":[35],"upon":[36],"binding.":[39],"latter":[41,157],"finding":[42],"observed":[44],"not":[45,248],"only":[46],"in":[47,52,57,114,147,174,239,290,321],"live":[48,179],"cells":[49],"but":[50],"also":[51],"isolated":[53],"membranes":[55],"and":[56,151,232,264,271],"an":[58,103,188],"electroeluted":[59],"protein.":[62,137],"Stimulation":[63],"of":[64,102,117,126,145,178,208,252,269,287,319],"by":[70,76,90],"completely":[74],"abolished":[75],"inhibitors,":[79],"which":[80],"effectively":[81],"inhibit":[82],"acrosome":[85,95,111,154,304],"reaction.":[86,155],"Since":[87],"oligomerization":[89],"ZP3":[91,146],"essential":[93],"reaction":[96,305],"triggering,":[97],"we":[98,122,213,242],"hypothesized":[99],"that":[100,164,190,203,245],"application":[101],"external":[104],"crosslinking":[105],"agent":[106],"will":[107],"lead":[108],"to":[109,170,216,295,311],"reaction,":[112],"even":[113],"absence":[116],"natural":[118],"ligand":[119],"Here,":[121],"report":[123],"generation":[125],"mouse":[128,218],"monoclonal":[129],"antibody":[130,189],"(mAb)":[131],"raised":[132],"against":[133],"This":[138],"antibody,":[139],"termed":[140],"LL95,":[141],"mimics":[142],"bioactivities":[144],"inhibiting":[148],"sperm-zona":[149,301],"binding":[150,302],"inducing":[152],"depends":[158],"oligomerization.":[161],"Immunolocalization":[162],"revealed":[163],"LL95":[166,182,233,246,265,278],"antigen":[167,234,279],"restricted":[169],"head":[172],"surface":[173],"acrosomal":[176],"region":[177],"sperm.":[180],"Thus,":[181],"fulfills":[183],"several":[184],"criteria":[185],"predicted":[186],"recognizes":[191,266],"pellucida.":[198],"Recently,":[199],"it":[200],"was":[201],"reported":[202],"amino":[205],"acid":[206],"sequence":[207],"described":[214],"corresponds":[215],"hepatoma":[219],"hexokinase":[220,231,258,283,320],"(Kalab":[221],"et":[222],"al.,":[223],"1994:":[224],"J":[225],"Biol":[226],"Chem":[227],"269:3810-3817).":[228],"Although":[229],"both":[230],"migrate":[235],"at":[236],"nonreducing":[240],"gels,":[241],"show":[243],"here":[244],"does":[247],"recognize":[249],"hexokinase.":[250],"Identification":[251],"different":[253],"proteins":[254,268],"clear":[256],"where":[257,282],"116":[261],"110":[270],"130":[272],"kD.":[273],"Moreover,":[274],"mAb":[275],"anti-phosphotyrosine":[276],"immunoprecipitates":[277],"under":[280],"conditions":[281],"absent.":[285],"Use":[286],"anti-hexokinase":[288],"antibodies":[289,309],"gamete":[291,322],"interaction":[292,323],"assays":[293],"failed":[294],"demonstrate":[296],"any":[297],"effect":[298],"either":[300],"or":[303],"triggering.":[306],"Finally,":[307],"antihexokinase":[308],"bind":[310],"tail":[314],"antigen,":[315],"thus":[316],"direct":[317],"involvement":[318],"seems":[324],"improbable.":[325]},"counts_by_year":[{"year":2022,"cited_by_count":1},{"year":2014,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}