{"id":"https://openalex.org/W1970516397","doi":"https://doi.org/10.1371/journal.pmed.0050064","title":"Statins Impair Antitumor Effects of Rituximab by Inducing Conformational Changes of CD20","display_name":"Statins Impair Antitumor Effects of Rituximab by Inducing Conformational Changes of CD20","publication_year":2008,"publication_date":"2008-03-19","ids":{"openalex":"https://openalex.org/W1970516397","doi":"https://doi.org/10.1371/journal.pmed.0050064","mag":"1970516397","pmid":"https://pubmed.ncbi.nlm.nih.gov/18366248","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/2270297"},"language":"en","primary_location":{"id":"doi:10.1371/journal.pmed.0050064","doi":"https://doi.org/10.1371/journal.pmed.0050064","is_oa":true,"landing_page_url":"https://doi.org/10.1371/journal.pmed.0050064","pdf_url":"https://journals.plos.org/plosmedicine/article/file?id=10.1371/journal.pmed.0050064&type=printable","source":{"id":"https://openalex.org/S197939330","display_name":"PLoS Medicine","issn_l":"1549-1277","issn":["1549-1277","1549-1676"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","doaj","dongbi-b","doyens","jufo-3","ki-jl-3","medline","norway-2","oarl","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315706","host_organization_name":"Public Library of Science","host_organization_lineage":["https://openalex.org/P4310315706"],"host_organization_lineage_names":["Public Library of Science"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLoS Medicine","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://journals.plos.org/plosmedicine/article/file?id=10.1371/journal.pmed.0050064&type=printable","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5082007741","display_name":"Magdalena Winiarska","orcid":"https://orcid.org/0000-0001-5605-3329","observed_orcids":["https://orcid.org/0000-0001-5605-3329"]},"institutions":[{"id":"https://openalex.org/I268303160","display_name":"Medical University of Warsaw","ror":"https://ror.org/04p2y4s44","country_code":"PL","type":"education","lineage":["https://openalex.org/I268303160"]}],"countries":["PL"],"is_corresponding":false,"raw_author_name":"Magdalena Winiarska","raw_affiliation_strings":["Department of Immunology, Center of Biostructure Research, the Medical University of Warsaw, Warsaw, Poland","Department of Laboratory Diagnostics and Clinical Immunology, the Medical University of Warsaw, Warsaw, Poland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Immunology, Center of Biostructure Research, the Medical University of Warsaw, Warsaw, Poland","institution_ids":["https://openalex.org/I268303160"]},{"raw_affiliation_string":"Department of Laboratory Diagnostics and Clinical Immunology, the Medical University of Warsaw, Warsaw, Poland","institution_ids":["https://openalex.org/I268303160"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5008789138","display_name":"Jacek Bil","orcid":"https://orcid.org/0000-0002-8724-5611","observed_orcids":["https://orcid.org/0000-0002-8724-5611"]},"institutions":[{"id":"https://openalex.org/I268303160","display_name":"Medical University of Warsaw","ror":"https://ror.org/04p2y4s44","country_code":"PL","type":"education","lineage":["https://openalex.org/I268303160"]}],"countries":["PL"],"is_corresponding":false,"raw_author_name":"Jacek Bil","raw_affiliation_strings":["Department of Immunology, Center of Biostructure Research, the Medical University of Warsaw, Warsaw, Poland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Immunology, Center of Biostructure Research, the Medical University of Warsaw, Warsaw, Poland","institution_ids":["https://openalex.org/I268303160"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110232715","display_name":"Ewa Wilczek","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I268303160","display_name":"Medical University of Warsaw","ror":"https://ror.org/04p2y4s44","country_code":"PL","type":"education","lineage":["https://openalex.org/I268303160"]}],"countries":["PL"],"is_corresponding":false,"raw_author_name":"Ewa Wilczek","raw_affiliation_strings":["Department of Pathology, Center of Biostructure Research, the Medical University of Warsaw, Warsaw, Poland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology, Center of Biostructure Research, the Medical University of Warsaw, Warsaw, Poland","institution_ids":["https://openalex.org/I268303160"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5070005083","display_name":"Grzegorz Marek Wilczynski","orcid":"https://orcid.org/0000-0001-6667-0291","observed_orcids":["https://orcid.org/0000-0001-6667-0291"]},"institutions":[{"id":"https://openalex.org/I16778253","display_name":"Instytut Biologii Do\u015bwiadczalnej im. Marcelego Nenckiego","ror":"https://ror.org/04waf7p94","country_code":"PL","type":"facility","lineage":["https://openalex.org/I16778253","https://openalex.org/I99542240"]}],"countries":["PL"],"is_corresponding":false,"raw_author_name":"Grzegorz M Wilczynski","raw_affiliation_strings":["Laboratory of Molecular and Systemic Neuromorphology, Nencki Institute of Experimental Biology, Warsaw, Poland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory of Molecular and Systemic Neuromorphology, Nencki Institute of Experimental Biology, Warsaw, Poland","institution_ids":["https://openalex.org/I16778253"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5087466733","display_name":"Ma\u0142gorzata Lekka","orcid":"https://orcid.org/0000-0003-0844-8662","observed_orcids":["https://orcid.org/0000-0003-0844-8662"]},"institutions":[{"id":"https://openalex.org/I4210106918","display_name":"Institute of Nuclear Physics, Polish Academy of Sciences","ror":"https://ror.org/01n78t774","country_code":"PL","type":"facility","lineage":["https://openalex.org/I4210106918","https://openalex.org/I99542240"]}],"countries":["PL"],"is_corresponding":false,"raw_author_name":"Malgorzata Lekka","raw_affiliation_strings":["Department of Applied Spectroscopy, The Henryk Niewodniczanski Institute of Nuclear Physics, Krakow, Poland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Applied Spectroscopy, The Henryk Niewodniczanski Institute of Nuclear Physics, Krakow, Poland","institution_ids":["https://openalex.org/I4210106918"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5087586287","display_name":"Patrick J. Engelberts","orcid":"https://orcid.org/0000-0002-6274-8554","observed_orcids":["https://orcid.org/0000-0002-6274-8554"]},"institutions":[{"id":"https://openalex.org/I4210102253","display_name":"Genmab (Netherlands)","ror":"https://ror.org/01ajp8153","country_code":"NL","type":"company","lineage":["https://openalex.org/I4210102253","https://openalex.org/I4210163256"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"Patrick J Engelberts","raw_affiliation_strings":["Genmab, Utrecht, The Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Genmab, Utrecht, The Netherlands","institution_ids":["https://openalex.org/I4210102253"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5005297214","display_name":"Wendy J.M. Mackus","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210102253","display_name":"Genmab (Netherlands)","ror":"https://ror.org/01ajp8153","country_code":"NL","type":"company","lineage":["https://openalex.org/I4210102253","https://openalex.org/I4210163256"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"Wendy J. M Mackus","raw_affiliation_strings":["Genmab, Utrecht, The Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Genmab, Utrecht, The Netherlands","institution_ids":["https://openalex.org/I4210102253"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108000029","display_name":"El\u017cbieta G\u00f3rska","orcid":"https://orcid.org/0000-0003-1647-3366","observed_orcids":["https://orcid.org/0000-0003-1647-3366"]},"institutions":[{"id":"https://openalex.org/I268303160","display_name":"Medical University of Warsaw","ror":"https://ror.org/04p2y4s44","country_code":"PL","type":"education","lineage":["https://openalex.org/I268303160"]}],"countries":["PL"],"is_corresponding":false,"raw_author_name":"Elzbieta Gorska","raw_affiliation_strings":["Department of Laboratory Diagnostics and Clinical Immunology, the Medical University of Warsaw, Warsaw, Poland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Laboratory Diagnostics and Clinical Immunology, the Medical University of Warsaw, Warsaw, Poland","institution_ids":["https://openalex.org/I268303160"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5041267508","display_name":"\u0141ukasz Bojarski","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210120699","display_name":"International Institute of Molecular and Cell Biology","ror":"https://ror.org/01y3dkx74","country_code":"PL","type":"facility","lineage":["https://openalex.org/I4210120699"]}],"countries":["PL"],"is_corresponding":false,"raw_author_name":"Lukasz Bojarski","raw_affiliation_strings":["Laboratory of Neurodegeneration, International Institute of Molecular and Cell Biology, Warsaw, Poland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory of Neurodegeneration, International Institute of Molecular and Cell Biology, Warsaw, Poland","institution_ids":["https://openalex.org/I4210120699"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5074420457","display_name":"Tomasz Stok\u0142osa","orcid":"https://orcid.org/0000-0001-6918-5056","observed_orcids":["https://orcid.org/0000-0001-6918-5056"]},"institutions":[{"id":"https://openalex.org/I268303160","display_name":"Medical University of Warsaw","ror":"https://ror.org/04p2y4s44","country_code":"PL","type":"education","lineage":["https://openalex.org/I268303160"]}],"countries":["PL"],"is_corresponding":false,"raw_author_name":"Tomasz Stoklosa","raw_affiliation_strings":["Department of Immunology, Center of Biostructure Research, the Medical University of Warsaw, Warsaw, Poland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Immunology, Center of Biostructure Research, the Medical University of Warsaw, Warsaw, Poland","institution_ids":["https://openalex.org/I268303160"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5065430527","display_name":"Dominika Nowis","orcid":"https://orcid.org/0000-0003-2748-9523","observed_orcids":["https://orcid.org/0000-0003-2748-9523"]},"institutions":[{"id":"https://openalex.org/I268303160","display_name":"Medical University of Warsaw","ror":"https://ror.org/04p2y4s44","country_code":"PL","type":"education","lineage":["https://openalex.org/I268303160"]}],"countries":["PL"],"is_corresponding":false,"raw_author_name":"Dominika Nowis","raw_affiliation_strings":["Department of Immunology, Center of Biostructure Research, the Medical University of Warsaw, Warsaw, Poland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Immunology, Center of Biostructure Research, the Medical University of Warsaw, Warsaw, Poland","institution_ids":["https://openalex.org/I268303160"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5068157368","display_name":"Zuzanna Kurzaj","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I268303160","display_name":"Medical University of Warsaw","ror":"https://ror.org/04p2y4s44","country_code":"PL","type":"education","lineage":["https://openalex.org/I268303160"]}],"countries":["PL"],"is_corresponding":false,"raw_author_name":"Zuzanna Kurzaj","raw_affiliation_strings":["Department of Immunology, Center of Biostructure Research, the Medical University of Warsaw, Warsaw, Poland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Immunology, Center of Biostructure Research, the Medical University of Warsaw, Warsaw, Poland","institution_ids":["https://openalex.org/I268303160"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5021954016","display_name":"Marcin Makowski","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I268303160","display_name":"Medical University of Warsaw","ror":"https://ror.org/04p2y4s44","country_code":"PL","type":"education","lineage":["https://openalex.org/I268303160"]}],"countries":["PL"],"is_corresponding":false,"raw_author_name":"Marcin Makowski","raw_affiliation_strings":["Department of Immunology, Center of Biostructure Research, the Medical University of Warsaw, Warsaw, Poland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Immunology, Center of Biostructure Research, the Medical University of Warsaw, Warsaw, Poland","institution_ids":["https://openalex.org/I268303160"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5076818258","display_name":"Eliza G\u0142odkowska\u2010Mr\u00f3wka","orcid":"https://orcid.org/0000-0002-5865-8425","observed_orcids":["https://orcid.org/0000-0002-5865-8425"]},"institutions":[{"id":"https://openalex.org/I268303160","display_name":"Medical University of Warsaw","ror":"https://ror.org/04p2y4s44","country_code":"PL","type":"education","lineage":["https://openalex.org/I268303160"]}],"countries":["PL"],"is_corresponding":false,"raw_author_name":"Eliza Glodkowska","raw_affiliation_strings":["Department of Immunology, Center of Biostructure Research, the Medical University of Warsaw, Warsaw, Poland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Immunology, Center of Biostructure Research, the Medical University of Warsaw, Warsaw, Poland","institution_ids":["https://openalex.org/I268303160"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5077742185","display_name":"Tadeusz Issat","orcid":"https://orcid.org/0000-0002-3647-3550","observed_orcids":["https://orcid.org/0000-0002-3647-3550"]},"institutions":[{"id":"https://openalex.org/I268303160","display_name":"Medical University of Warsaw","ror":"https://ror.org/04p2y4s44","country_code":"PL","type":"education","lineage":["https://openalex.org/I268303160"]}],"countries":["PL"],"is_corresponding":false,"raw_author_name":"Tadeusz Issat","raw_affiliation_strings":["Department of Immunology, Center of Biostructure Research, the Medical University of Warsaw, Warsaw, Poland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Immunology, Center of Biostructure Research, the Medical University of Warsaw, Warsaw, Poland","institution_ids":["https://openalex.org/I268303160"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5021040941","display_name":"Piotr Mr\u00f3wka","orcid":"https://orcid.org/0000-0002-4300-7267","observed_orcids":["https://orcid.org/0000-0002-4300-7267"]},"institutions":[{"id":"https://openalex.org/I268303160","display_name":"Medical University of Warsaw","ror":"https://ror.org/04p2y4s44","country_code":"PL","type":"education","lineage":["https://openalex.org/I268303160"]}],"countries":["PL"],"is_corresponding":false,"raw_author_name":"Piotr Mrowka","raw_affiliation_strings":["Department of Immunology, Center of Biostructure Research, the Medical University of Warsaw, Warsaw, Poland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Immunology, Center of Biostructure Research, the Medical University of Warsaw, Warsaw, Poland","institution_ids":["https://openalex.org/I268303160"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5066081320","display_name":"Witold Lasek","orcid":"https://orcid.org/0000-0002-6156-055X","observed_orcids":["https://orcid.org/0000-0002-6156-055X"]},"institutions":[{"id":"https://openalex.org/I268303160","display_name":"Medical University of Warsaw","ror":"https://ror.org/04p2y4s44","country_code":"PL","type":"education","lineage":["https://openalex.org/I268303160"]}],"countries":["PL"],"is_corresponding":false,"raw_author_name":"Witold Lasek","raw_affiliation_strings":["Department of Immunology, Center of Biostructure Research, the Medical University of Warsaw, Warsaw, Poland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Immunology, Center of Biostructure Research, the Medical University of Warsaw, Warsaw, Poland","institution_ids":["https://openalex.org/I268303160"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5074447534","display_name":"Anna Paulina Dabrowska-Iwanicka","orcid":"https://orcid.org/0000-0001-8986-0397","observed_orcids":["https://orcid.org/0000-0001-8986-0397"]},"institutions":[{"id":"https://openalex.org/I4210150880","display_name":"The Maria Sklodowska-Curie National Research Institute of Oncology","ror":"https://ror.org/04qcjsm24","country_code":"PL","type":"healthcare","lineage":["https://openalex.org/I4210150880"]}],"countries":["PL"],"is_corresponding":false,"raw_author_name":"Anna Dabrowska-Iwanicka","raw_affiliation_strings":["Department of Lymphoproliferative Disease, Maria Sklodowska-Curie Memorial Cancer Center, Institute of Oncology, Warsaw, Poland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Lymphoproliferative Disease, Maria Sklodowska-Curie Memorial Cancer Center, Institute of Oncology, Warsaw, Poland","institution_ids":["https://openalex.org/I4210150880"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5053012296","display_name":"Grzegorz W\u0142adys\u0142aw Basak","orcid":"https://orcid.org/0000-0003-3858-8180","observed_orcids":["https://orcid.org/0000-0003-3858-8180"]},"institutions":[{"id":"https://openalex.org/I268303160","display_name":"Medical University of Warsaw","ror":"https://ror.org/04p2y4s44","country_code":"PL","type":"education","lineage":["https://openalex.org/I268303160"]}],"countries":["PL"],"is_corresponding":false,"raw_author_name":"Grzegorz W Basak","raw_affiliation_strings":["Department of Hematology, Oncology and Internal Diseases, the Medical University of Warsaw, Warsaw, Poland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Hematology, Oncology and Internal Diseases, the Medical University of Warsaw, Warsaw, Poland","institution_ids":["https://openalex.org/I268303160"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5035664310","display_name":"M Wasik","orcid":"https://orcid.org/0009-0007-8163-4265","observed_orcids":["https://orcid.org/0009-0007-8163-4265"]},"institutions":[{"id":"https://openalex.org/I268303160","display_name":"Medical University of Warsaw","ror":"https://ror.org/04p2y4s44","country_code":"PL","type":"education","lineage":["https://openalex.org/I268303160"]}],"countries":["PL"],"is_corresponding":false,"raw_author_name":"Maria Wasik","raw_affiliation_strings":["Department of Laboratory Diagnostics and Clinical Immunology, the Medical University of Warsaw, Warsaw, Poland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Laboratory Diagnostics and Clinical Immunology, the Medical University of Warsaw, Warsaw, Poland","institution_ids":["https://openalex.org/I268303160"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5019711205","display_name":"Krzysztof Warzocha","orcid":"https://orcid.org/0000-0002-2396-3905","observed_orcids":["https://orcid.org/0000-0002-2396-3905"]},"institutions":[{"id":"https://openalex.org/I4210090876","display_name":"Instytut Hematologii i Transfuzjologi","ror":"https://ror.org/00csw7971","country_code":"PL","type":"facility","lineage":["https://openalex.org/I4210090876"]}],"countries":["PL"],"is_corresponding":false,"raw_author_name":"Krzysztof Warzocha","raw_affiliation_strings":["Institute of Hematology and Transfusion Medicine, Warsaw, Poland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Hematology and Transfusion Medicine, Warsaw, Poland","institution_ids":["https://openalex.org/I4210090876"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5073036014","display_name":"Maciej Si\u0144ski","orcid":"https://orcid.org/0000-0001-8548-9762","observed_orcids":["https://orcid.org/0000-0001-8548-9762"]},"institutions":[{"id":"https://openalex.org/I268303160","display_name":"Medical University of Warsaw","ror":"https://ror.org/04p2y4s44","country_code":"PL","type":"education","lineage":["https://openalex.org/I268303160"]}],"countries":["PL"],"is_corresponding":false,"raw_author_name":"Maciej Sinski","raw_affiliation_strings":["Department of Internal Diseases, Hypertension and Vascular Disease, the Medical University of Warsaw, Warsaw, Poland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Internal Diseases, Hypertension and Vascular Disease, the Medical University of Warsaw, Warsaw, Poland","institution_ids":["https://openalex.org/I268303160"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5000630097","display_name":"Zbigniew A. Gaciong","orcid":"https://orcid.org/0000-0002-6666-3734","observed_orcids":["https://orcid.org/0000-0002-6666-3734"]},"institutions":[{"id":"https://openalex.org/I268303160","display_name":"Medical University of Warsaw","ror":"https://ror.org/04p2y4s44","country_code":"PL","type":"education","lineage":["https://openalex.org/I268303160"]}],"countries":["PL"],"is_corresponding":false,"raw_author_name":"Zbigniew Gaciong","raw_affiliation_strings":["Department of Internal Diseases, Hypertension and Vascular Disease, the Medical University of Warsaw, Warsaw, Poland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Internal Diseases, Hypertension and Vascular Disease, the Medical University of Warsaw, Warsaw, Poland","institution_ids":["https://openalex.org/I268303160"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110321613","display_name":"Marek Jak\u00f3bisiak","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I268303160","display_name":"Medical University of Warsaw","ror":"https://ror.org/04p2y4s44","country_code":"PL","type":"education","lineage":["https://openalex.org/I268303160"]}],"countries":["PL"],"is_corresponding":false,"raw_author_name":"Marek Jakobisiak","raw_affiliation_strings":["Department of Immunology, Center of Biostructure Research, the Medical University of Warsaw, Warsaw, Poland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Immunology, Center of Biostructure Research, the Medical University of Warsaw, Warsaw, Poland","institution_ids":["https://openalex.org/I268303160"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5039190287","display_name":"Paul W.H.I. Parren","orcid":"https://orcid.org/0000-0002-4365-3859","observed_orcids":["https://orcid.org/0000-0002-4365-3859"]},"institutions":[{"id":"https://openalex.org/I4210102253","display_name":"Genmab (Netherlands)","ror":"https://ror.org/01ajp8153","country_code":"NL","type":"company","lineage":["https://openalex.org/I4210102253","https://openalex.org/I4210163256"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"Paul W. H. I Parren","raw_affiliation_strings":["Genmab, Utrecht, The Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Genmab, Utrecht, The Netherlands","institution_ids":["https://openalex.org/I4210102253"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5038751267","display_name":"Jakub Go\u0142\u0105b","orcid":"https://orcid.org/0000-0002-2830-5100","observed_orcids":["https://orcid.org/0000-0002-2830-5100"]},"institutions":[{"id":"https://openalex.org/I268303160","display_name":"Medical University of Warsaw","ror":"https://ror.org/04p2y4s44","country_code":"PL","type":"education","lineage":["https://openalex.org/I268303160"]}],"countries":["PL"],"is_corresponding":true,"raw_author_name":"Jakub Golab","raw_affiliation_strings":["Department of Immunology, Center of Biostructure Research, the Medical University of Warsaw, Warsaw, Poland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Immunology, Center of Biostructure Research, the Medical University of Warsaw, Warsaw, Poland","institution_ids":["https://openalex.org/I268303160"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":7,"corresponding_author_ids":["https://openalex.org/A5038751267"],"corresponding_institution_ids":["https://openalex.org/I268303160"],"apc_list":{"value":6460,"currency":"USD","value_usd":6460},"apc_paid":{"value":6460,"currency":"USD","value_usd":6460},"fwci":11.8045,"has_fulltext":true,"cited_by_count":127,"citation_normalized_percentile":{"value":0.98735586,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":89,"max":100},"biblio":{"volume":"5","issue":"3","first_page":"e64","last_page":"e64"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10185","display_name":"Lymphoma Diagnosis and Treatment","score":0.7432000041007996,"subfield":{"id":"https://openalex.org/subfields/2734","display_name":"Pathology and Forensic Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10185","display_name":"Lymphoma Diagnosis and Treatment","score":0.7432000041007996,"subfield":{"id":"https://openalex.org/subfields/2734","display_name":"Pathology and Forensic Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12465","display_name":"Cancer, Lipids, and Metabolism","score":0.09669999778270721,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11016","display_name":"Monoclonal and Polyclonal Antibodies Research","score":0.058800000697374344,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/statins","display_name":"statins","score":0.9269999861717224},{"id":"https://openalex.org/keywords/rituximab","display_name":"rituximab","score":1.0},{"id":"https://openalex.org/keywords/cd20","display_name":"CD20","score":0.9879999756813049},{"id":"https://openalex.org/keywords/b-cell-lymphoma","display_name":"B-cell lymphoma","score":0.953000009059906},{"id":"https://openalex.org/keywords/cholesterol-depletion","display_name":"cholesterol depletion","score":0.7210000157356262},{"id":"https://openalex.org/keywords/plasma-membrane-cholesterol","display_name":"plasma membrane cholesterol","score":0.7509999871253967},{"id":"https://openalex.org/keywords/conformational-epitopes","display_name":"conformational epitopes","score":0.7609999775886536},{"id":"https://openalex.org/keywords/antibody-binding","display_name":"antibody binding","score":0.7009999752044678},{"id":"https://openalex.org/keywords/complement-dependent-cytotoxicity","display_name":"complement-dependent cytotoxicity","score":0.9819999933242798},{"id":"https://openalex.org/keywords/antibody-dependent-cellular-cytotoxicity","display_name":"antibody-dependent cellular cytotoxicity","score":0.9990000128746033},{"id":"https://openalex.org/keywords/drug-drug-interactions","display_name":"drug-drug interactions","score":0.6230000257492065},{"id":"https://openalex.org/keywords/atorvastatin","display_name":"atorvastatin","score":0.8870000243186951},{"id":"https://openalex.org/keywords/hypercholesterolemia","display_name":"hypercholesterolemia","score":0.9079999923706055},{"id":"https://openalex.org/keywords/methyl-beta-cyclodextrin","display_name":"methyl-\u03b2-cyclodextrin","score":0.8320000171661377},{"id":"https://openalex.org/keywords/berberine","display_name":"berberine","score":0.8339999914169312},{"id":"https://openalex.org/keywords/filipin-iii","display_name":"filipin III","score":0.824999988079071},{"id":"https://openalex.org/keywords/lipid-rafts","display_name":"lipid rafts","score":0.9190000295639038}],"concepts":[{"id":"https://openalex.org/C40677261","wikidata":"https://www.wikidata.org/wiki/Q21418091","display_name":"Antibody-dependent cell-mediated cytotoxicity","level":4,"score":0.6713283061981201},{"id":"https://openalex.org/C2778714382","wikidata":"https://www.wikidata.org/wiki/Q410656","display_name":"Ofatumumab","level":4,"score":0.6634423732757568},{"id":"https://openalex.org/C79266657","wikidata":"https://www.wikidata.org/wiki/Q424178","display_name":"Lipid raft","level":3,"score":0.6429471373558044},{"id":"https://openalex.org/C18031839","wikidata":"https://www.wikidata.org/wiki/Q5009796","display_name":"CD20","level":3,"score":0.5927284955978394},{"id":"https://openalex.org/C195616568","wikidata":"https://www.wikidata.org/wiki/Q128711","display_name":"Epitope","level":3,"score":0.5820247530937195},{"id":"https://openalex.org/C109316439","wikidata":"https://www.wikidata.org/wiki/Q246181","display_name":"Cytotoxicity","level":3,"score":0.576981246471405},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.5357282757759094},{"id":"https://openalex.org/C153911025","wikidata":"https://www.wikidata.org/wiki/Q7202","display_name":"Molecular biology","level":1,"score":0.47928470373153687},{"id":"https://openalex.org/C2780653079","wikidata":"https://www.wikidata.org/wiki/Q412323","display_name":"Rituximab","level":3,"score":0.47171351313591003},{"id":"https://openalex.org/C542903549","wikidata":"https://www.wikidata.org/wiki/Q422248","display_name":"Monoclonal antibody","level":3,"score":0.4558213949203491},{"id":"https://openalex.org/C553184892","wikidata":"https://www.wikidata.org/wiki/Q1141429","display_name":"Flow cytometry","level":2,"score":0.416837215423584},{"id":"https://openalex.org/C159654299","wikidata":"https://www.wikidata.org/wiki/Q79460","display_name":"Antibody","level":2,"score":0.40145108103752136},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.38309505581855774},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.3644958734512329},{"id":"https://openalex.org/C2778163477","wikidata":"https://www.wikidata.org/wiki/Q43656","display_name":"Cholesterol","level":2,"score":0.3060842752456665},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.28029173612594604},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.2748625874519348},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.27187633514404297},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.26731157302856445},{"id":"https://openalex.org/C202751555","wikidata":"https://www.wikidata.org/wiki/Q221681","display_name":"In vitro","level":2,"score":0.22505882382392883}],"mesh":[{"descriptor_ui":"D000069283","descriptor_name":"Rituximab","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000911","descriptor_name":"Antibodies, Monoclonal","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D000911","descriptor_name":"Antibodies, Monoclonal","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D000911","descriptor_name":"Antibodies, Monoclonal","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D000920","descriptor_name":"Antibody-Dependent Cell Cytotoxicity","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D000970","descriptor_name":"Antineoplastic Agents","qualifier_ui":"Q000037","qualifier_name":"antagonists & inhibitors","is_major_topic":true},{"descriptor_ui":"D001402","descriptor_name":"B-Lymphocytes","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D002784","descriptor_name":"Cholesterol","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D003602","descriptor_name":"Cytotoxicity, Immunologic","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006937","descriptor_name":"Hypercholesterolemia","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D006937","descriptor_name":"Hypercholesterolemia","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":false},{"descriptor_ui":"D008148","descriptor_name":"Lovastatin","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D011487","descriptor_name":"Protein Conformation","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D016393","descriptor_name":"Lymphoma, B-Cell","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D018951","descriptor_name":"Antigens, CD20","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D018951","descriptor_name":"Antigens, CD20","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D019161","descriptor_name":"Hydroxymethylglutaryl-CoA Reductase Inhibitors","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":true},{"descriptor_ui":"D021962","descriptor_name":"Membrane Microdomains","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D045744","descriptor_name":"Cell Line, Tumor","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D058846","descriptor_name":"Antibodies, Monoclonal, Murine-Derived","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.1371/journal.pmed.0050064","doi":"https://doi.org/10.1371/journal.pmed.0050064","is_oa":true,"landing_page_url":"https://doi.org/10.1371/journal.pmed.0050064","pdf_url":"https://journals.plos.org/plosmedicine/article/file?id=10.1371/journal.pmed.0050064&type=printable","source":{"id":"https://openalex.org/S197939330","display_name":"PLoS Medicine","issn_l":"1549-1277","issn":["1549-1277","1549-1676"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","doaj","dongbi-b","doyens","jufo-3","ki-jl-3","medline","norway-2","oarl","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315706","host_organization_name":"Public Library of Science","host_organization_lineage":["https://openalex.org/P4310315706"],"host_organization_lineage_names":["Public Library of Science"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLoS Medicine","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:2270297","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/2270297","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLoS Med","raw_type":"Text"},{"id":"pmid:18366248","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/18366248","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLoS medicine","raw_type":"Journal Article"},{"id":"pmh:oai:doaj.org/article:8a6f737eb02e4bb2b26604dc216cc95b","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/8a6f737eb02e4bb2b26604dc216cc95b","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"PLoS Medicine, Vol 5, Iss 3, p e64 (2008)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.1371/journal.pmed.0050064","doi":"https://doi.org/10.1371/journal.pmed.0050064","is_oa":true,"landing_page_url":"https://doi.org/10.1371/journal.pmed.0050064","pdf_url":"https://journals.plos.org/plosmedicine/article/file?id=10.1371/journal.pmed.0050064&type=printable","source":{"id":"https://openalex.org/S197939330","display_name":"PLoS Medicine","issn_l":"1549-1277","issn":["1549-1277","1549-1676"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","doaj","dongbi-b","doyens","jufo-3","ki-jl-3","medline","norway-2","oarl","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315706","host_organization_name":"Public Library of Science","host_organization_lineage":["https://openalex.org/P4310315706"],"host_organization_lineage_names":["Public Library of Science"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLoS Medicine","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.98580002784729}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320321042","display_name":"Fundacja na rzecz Nauki Polskiej","ror":"https://ror.org/048zd9m77"},{"id":"https://openalex.org/F4320322412","display_name":"Warszawski Uniwersytet Medyczny","ror":"https://ror.org/04p2y4s44"},{"id":"https://openalex.org/F4320323873","display_name":"Uniwersytet Warszawski","ror":"https://ror.org/039bjqg32"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W1970516397.pdf","grobid_xml":"https://content.openalex.org/works/W1970516397.grobid-xml"},"referenced_works_count":47,"referenced_works":["https://openalex.org/W1496861468","https://openalex.org/W1509374036","https://openalex.org/W1520633728","https://openalex.org/W1866667399","https://openalex.org/W1915689252","https://openalex.org/W1960631461","https://openalex.org/W1964839598","https://openalex.org/W1976537150","https://openalex.org/W1985578471","https://openalex.org/W1987898211","https://openalex.org/W1988596351","https://openalex.org/W2009512645","https://openalex.org/W2012700557","https://openalex.org/W2013797019","https://openalex.org/W2020622193","https://openalex.org/W2027374210","https://openalex.org/W2036251477","https://openalex.org/W2038009322","https://openalex.org/W2038043209","https://openalex.org/W2043946207","https://openalex.org/W2049848440","https://openalex.org/W2057792828","https://openalex.org/W2065246270","https://openalex.org/W2065900855","https://openalex.org/W2075683667","https://openalex.org/W2076932649","https://openalex.org/W2078807282","https://openalex.org/W2084648638","https://openalex.org/W2086024671","https://openalex.org/W2088030566","https://openalex.org/W2090738000","https://openalex.org/W2094241271","https://openalex.org/W2095101852","https://openalex.org/W2109182290","https://openalex.org/W2115099549","https://openalex.org/W2122725450","https://openalex.org/W2129582474","https://openalex.org/W2132659447","https://openalex.org/W2132867392","https://openalex.org/W2135474694","https://openalex.org/W2137151756","https://openalex.org/W2138916760","https://openalex.org/W2145653235","https://openalex.org/W2149287539","https://openalex.org/W2162912795","https://openalex.org/W3021879095","https://openalex.org/W4233116228"],"related_works":["https://openalex.org/W2530074130","https://openalex.org/W6921037071","https://openalex.org/W6977781906","https://openalex.org/W6920980646","https://openalex.org/W6939802572","https://openalex.org/W6977341183","https://openalex.org/W1994970796","https://openalex.org/W1998994694","https://openalex.org/W2127278504","https://openalex.org/W4231208434"],"abstract_inverted_index":{"BACKGROUND:":[0],"Rituximab":[1],"is":[2,166,193],"used":[3],"in":[4,119,195,199,202,222,226,233,250],"the":[5,50,156,196],"treatment":[6,241],"of":[7,44,52,57,103,109,130,158,229,236,242,268,273,284,289,304],"CD20+":[8],"B":[9,14,58,104,110,257],"cell":[10,15,59,105,111],"lymphomas":[11],"and":[12,37,71,81,101,136,148,162,185,204,210,270],"other":[13,28,144],"lymphoproliferative":[16],"disorders.":[17],"Its":[18],"clinical":[19,279],"efficacy":[20],"might":[21],"be":[22],"further":[23],"improved":[24],"by":[25,69,88,143,239,292],"combinations":[26],"with":[27,114,134,176,245,247,265],"drugs":[29],"such":[30],"as":[31,75,77,132,281],"statins":[32,53,115,293],"that":[33,155,191,214,224],"inhibit":[34],"cholesterol":[35,161,217,237],"synthesis":[36],"show":[38],"promising":[39],"antilymphoma":[40,271],"effects.":[41],"The":[42],"objective":[43],"this":[45],"study":[46],"was":[47,67,86],"to":[48,96,254,263,286],"evaluate":[49],"influence":[51],"on":[54],"rituximab-induced":[55],"killing":[56],"lymphomas.":[60],"METHODS":[61],"AND":[62],"FINDINGS:":[63],"Complement-dependent":[64],"cytotoxicity":[65,84],"(CDC)":[66],"assessed":[68,87],"MTT":[70],"Alamar":[72],"blue":[73,79],"assays":[74],"well":[76],"trypan":[78],"staining,":[80],"antibody-dependent":[82],"cellular":[83,128],"(ADCC)":[85],"a":[89,182,186],"51Cr":[90],"release":[91],"assay.":[92],"Statins":[93,260],"were":[94,261],"found":[95],"significantly":[97],"decrease":[98],"rituximab-mediated":[99,169],"CDC":[100],"ADCC":[102],"lymphoma":[106,112],"cells.":[107,206,258],"Incubation":[108],"cells":[113],"decreased":[116],"CD20":[117,131,192,223,269,290],"immunostaining":[118],"flow":[120],"cytometry":[121],"studies":[122,276],"but":[123,150],"did":[124],"not":[125,151,163],"affect":[126],"total":[127],"levels":[129],"measured":[133],"RT-PCR":[135],"Western":[137],"blotting.":[138],"Similar":[139],"effects":[140],"are":[141],"exerted":[142],"cholesterol-depleting":[145],"agents":[146],"(methyl-beta-cyclodextrin":[147],"berberine),":[149],"filipin":[152],"III,":[153],"indicating":[154],"presence":[157],"plasma":[159,197],"membrane":[160,198],"lipid":[164],"rafts":[165],"required":[167],"for":[168],"CDC.":[170],"Immunofluorescence":[171],"microscopy":[172,209],"using":[173],"double":[174],"staining":[175],"monoclonal":[177],"antibodies":[178],"(mAbs)":[179],"directed":[180],"against":[181],"conformational":[183,220,287],"epitope":[184,189],"linear":[187],"cytoplasmic":[188],"revealed":[190],"present":[194],"comparable":[200],"amounts":[201],"control":[203],"statin-treated":[205],"Atomic":[207],"force":[208],"limited":[211],"proteolysis":[212],"indicated":[213],"statins,":[215],"through":[216],"depletion,":[218],"induce":[219],"changes":[221],"result":[225],"impaired":[227,282],"binding":[228,253,283],"anti-CD20":[230,252],"mAb.":[231],"An":[232],"vivo":[234],"reduction":[235],"induced":[238],"short-term":[240],"five":[243],"patients":[244],"hypercholesterolemia":[246],"atorvastatin":[248],"resulted":[249],"reduced":[251],"freshly":[255],"isolated":[256],"CONCLUSIONS:":[259],"shown":[262],"interfere":[264],"both":[266],"detection":[267],"activity":[272,303],"rituximab.":[274,305],"These":[275],"have":[277],"significant":[278],"implications,":[280],"mAbs":[285],"epitopes":[288],"elicited":[291],"could":[294],"delay":[295],"diagnosis,":[296],"postpone":[297],"effective":[298],"treatment,":[299],"or":[300],"impair":[301],"anti-lymphoma":[302]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":3},{"year":2023,"cited_by_count":7},{"year":2022,"cited_by_count":4},{"year":2021,"cited_by_count":3},{"year":2020,"cited_by_count":5},{"year":2019,"cited_by_count":2},{"year":2018,"cited_by_count":5},{"year":2017,"cited_by_count":5},{"year":2016,"cited_by_count":7},{"year":2015,"cited_by_count":11},{"year":2014,"cited_by_count":16},{"year":2013,"cited_by_count":9},{"year":2012,"cited_by_count":9}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2016-06-24T00:00:00"}