{"id":"https://openalex.org/W1970367752","doi":"https://doi.org/10.4103/0973-1482.113340","title":"Molecular biology of oral sub mucous fibrosis","display_name":"Molecular biology of oral sub mucous fibrosis","publication_year":2013,"publication_date":"2013-01-01","ids":{"openalex":"https://openalex.org/W1970367752","doi":"https://doi.org/10.4103/0973-1482.113340","mag":"1970367752","pmid":"https://pubmed.ncbi.nlm.nih.gov/23771354"},"language":"en","primary_location":{"id":"doi:10.4103/0973-1482.113340","doi":"https://doi.org/10.4103/0973-1482.113340","is_oa":true,"landing_page_url":"https://doi.org/10.4103/0973-1482.113340","pdf_url":null,"source":{"id":"https://openalex.org/S53738828","display_name":"Journal of Cancer Research and Therapeutics","issn_l":"1998-4138","issn":["1998-4138","0973-1482"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","jufo-1","ki-jl-1","medline","norway-1","poland-40","russia-white-list-3"],"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Cancer Research and Therapeutics","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"diamond","oa_url":"https://doi.org/10.4103/0973-1482.113340","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5049777255","display_name":"K. Saravanan","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I175548057","display_name":"Vinayaka Missions University","ror":"https://ror.org/03wt62c10","country_code":"IN","type":"education","lineage":["https://openalex.org/I175548057"]}],"countries":["IN"],"is_corresponding":true,"raw_author_name":"K Saravanan","raw_affiliation_strings":["Department of Oral and Maxillofacial Surgery,Vinayaka Mission's Sankarachariyar Dental College and Hospital, Vinayaka Missions Deemed University, Sankari Main Road, Ariyanoor, Salem, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Oral and Maxillofacial Surgery,Vinayaka Mission's Sankarachariyar Dental College and Hospital, Vinayaka Missions Deemed University, Sankari Main Road, Ariyanoor, Salem, India","institution_ids":["https://openalex.org/I175548057"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111533871","display_name":"MKodanda Ram","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4405255938","display_name":"Kannur Dental College","ror":"https://ror.org/03khan160","country_code":"IN","type":"education","lineage":["https://openalex.org/I4405255938"]},{"id":"https://openalex.org/I52703040","display_name":"Kannur University","ror":"https://ror.org/00zz2cd87","country_code":"IN","type":"education","lineage":["https://openalex.org/I52703040"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"MKodanda Ram","raw_affiliation_strings":["Department of Oral Pathology, Kannur Dental College, Kannur university, Kerala, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Oral Pathology, Kannur Dental College, Kannur university, Kerala, India","institution_ids":["https://openalex.org/I4405255938","https://openalex.org/I52703040"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5024581808","display_name":"Rajendran Ganesh","orcid":"https://orcid.org/0000-0002-3700-8212","observed_orcids":["https://orcid.org/0000-0002-3700-8212"]},"institutions":[{"id":"https://openalex.org/I4210101314","display_name":"SRM Dental College","ror":"https://ror.org/01bd1sf38","country_code":"IN","type":"education","lineage":["https://openalex.org/I145286018","https://openalex.org/I4210101314"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"R Ganesh","raw_affiliation_strings":["Department of Pedodontics, SRM Dental College, SRM deemed university, Ramapuram, Chennai, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pedodontics, SRM Dental College, SRM deemed university, Ramapuram, Chennai, India","institution_ids":["https://openalex.org/I4210101314"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5049777255"],"corresponding_institution_ids":["https://openalex.org/I175548057"],"apc_list":null,"apc_paid":null,"fwci":1.638,"has_fulltext":false,"cited_by_count":15,"citation_normalized_percentile":{"value":0.80777238,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":98},"biblio":{"volume":"9","issue":"2","first_page":"179","last_page":"179"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11452","display_name":"Oral Health Pathology and Treatment","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/3500","display_name":"General Dentistry"},"field":{"id":"https://openalex.org/fields/35","display_name":"Dentistry"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11452","display_name":"Oral Health Pathology and Treatment","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/3500","display_name":"General Dentistry"},"field":{"id":"https://openalex.org/fields/35","display_name":"Dentistry"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10307","display_name":"Head and Neck Cancer Studies","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/2733","display_name":"Otorhinolaryngology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12198","display_name":"Oral health in cancer treatment","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/3500","display_name":"General Dentistry"},"field":{"id":"https://openalex.org/fields/35","display_name":"Dentistry"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/oral-submucous-fibrosis","display_name":"oral submucous fibrosis","score":0.996999979019165},{"id":"https://openalex.org/keywords/oral-squamous-cell-carcinoma","display_name":"oral squamous cell carcinoma","score":0.8349999785423279},{"id":"https://openalex.org/keywords/betel-nut-chewing","display_name":"betel quid chewing","score":0.9190000295639038},{"id":"https://openalex.org/keywords/malignant-transformation","display_name":"malignant transformation","score":0.9570000171661377},{"id":"https://openalex.org/keywords/molecular-pathogenesis","display_name":"molecular pathogenesis","score":0.6169999837875366},{"id":"https://openalex.org/keywords/oral-cancer-risk-factors","display_name":"oral cancer risk factors","score":0.6330000162124634}],"concepts":[{"id":"https://openalex.org/C2780672762","wikidata":"https://www.wikidata.org/wiki/Q7099404","display_name":"Oral submucous fibrosis","level":2,"score":0.7017489671707153},{"id":"https://openalex.org/C2780559512","wikidata":"https://www.wikidata.org/wiki/Q605709","display_name":"Fibrosis","level":2,"score":0.5740329027175903},{"id":"https://openalex.org/C2777417228","wikidata":"https://www.wikidata.org/wiki/Q159532","display_name":"Betel","level":3,"score":0.5494552850723267},{"id":"https://openalex.org/C2991810699","wikidata":"https://www.wikidata.org/wiki/Q60140","display_name":"Indian subcontinent","level":2,"score":0.549248456954956},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.5232343077659607},{"id":"https://openalex.org/C2779409057","wikidata":"https://www.wikidata.org/wiki/Q1776131","display_name":"Oral mucosa","level":2,"score":0.5177385210990906},{"id":"https://openalex.org/C3019992690","wikidata":"https://www.wikidata.org/wiki/Q92767510","display_name":"Basal cell","level":2,"score":0.5175694823265076},{"id":"https://openalex.org/C2986629439","wikidata":"https://www.wikidata.org/wiki/Q9635","display_name":"Oral cavity","level":2,"score":0.48577073216438293},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.4668090343475342},{"id":"https://openalex.org/C16005928","wikidata":"https://www.wikidata.org/wiki/Q171171","display_name":"Dermatology","level":1,"score":0.4049515724182129},{"id":"https://openalex.org/C90924648","wikidata":"https://www.wikidata.org/wiki/Q120569","display_name":"Gastroenterology","level":1,"score":0.37797287106513977},{"id":"https://openalex.org/C199343813","wikidata":"https://www.wikidata.org/wiki/Q12128","display_name":"Dentistry","level":1,"score":0.21548709273338318},{"id":"https://openalex.org/C206391251","wikidata":"https://www.wikidata.org/wiki/Q1186738","display_name":"Nut","level":2,"score":0.0},{"id":"https://openalex.org/C195244886","wikidata":"https://www.wikidata.org/wiki/Q41493","display_name":"Ancient history","level":1,"score":0.0},{"id":"https://openalex.org/C95457728","wikidata":"https://www.wikidata.org/wiki/Q309","display_name":"History","level":0,"score":0.0},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.0},{"id":"https://openalex.org/C66938386","wikidata":"https://www.wikidata.org/wiki/Q633538","display_name":"Structural engineering","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D002471","descriptor_name":"Cell Transformation, Neoplastic","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D002471","descriptor_name":"Cell Transformation, Neoplastic","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D002471","descriptor_name":"Cell Transformation, Neoplastic","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008967","descriptor_name":"Molecular Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D009055","descriptor_name":"Mouth","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D009055","descriptor_name":"Mouth","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D009914","descriptor_name":"Oral Submucous Fibrosis","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D009914","descriptor_name":"Oral Submucous Fibrosis","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D009914","descriptor_name":"Oral Submucous Fibrosis","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.4103/0973-1482.113340","doi":"https://doi.org/10.4103/0973-1482.113340","is_oa":true,"landing_page_url":"https://doi.org/10.4103/0973-1482.113340","pdf_url":null,"source":{"id":"https://openalex.org/S53738828","display_name":"Journal of Cancer Research and Therapeutics","issn_l":"1998-4138","issn":["1998-4138","0973-1482"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","jufo-1","ki-jl-1","medline","norway-1","poland-40","russia-white-list-3"],"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Cancer Research and Therapeutics","raw_type":"journal-article"},{"id":"pmid:23771354","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/23771354","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of cancer research and therapeutics","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.4103/0973-1482.113340","doi":"https://doi.org/10.4103/0973-1482.113340","is_oa":true,"landing_page_url":"https://doi.org/10.4103/0973-1482.113340","pdf_url":null,"source":{"id":"https://openalex.org/S53738828","display_name":"Journal of Cancer Research and Therapeutics","issn_l":"1998-4138","issn":["1998-4138","0973-1482"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","jufo-1","ki-jl-1","medline","norway-1","poland-40","russia-white-list-3"],"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Cancer Research and Therapeutics","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.9922999739646912,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2019565246","https://openalex.org/W1596185934","https://openalex.org/W1975525526","https://openalex.org/W3081482866","https://openalex.org/W2046098239","https://openalex.org/W2054960773","https://openalex.org/W2350507902","https://openalex.org/W2442177519","https://openalex.org/W1967490625","https://openalex.org/W1987012072"],"abstract_inverted_index":{"Oral":[0,43],"sub":[1,20,44,60],"mucous":[2,21,45,61],"fibrosis":[3,22,46],"is":[4,68,87],"an":[5],"insidious":[6],"chronic":[7],"disease":[8],"affecting":[9],"any":[10],"part":[11],"of":[12,18,55,82,99],"the":[13,35,75,90,97],"oral":[14,19,59,64,83],"cavity.":[15],"Worldwide":[16],"estimates":[17],"indicate":[23],"that":[24,96],"2.5":[25],"million":[26],"people":[27],"are":[28],"affected,":[29],"with":[30,89],"most":[31],"cases":[32],"concentrated":[33],"in":[34,72],"Indian":[36,76],"subcontinent,":[37],"especially":[38,71],"eastern":[39],"and":[40,63,74],"southern":[41],"India.":[42],"has":[47],"a":[48],"propensity":[49],"for":[50],"malignant":[51,100],"transformation.":[52],"The":[53],"association":[54],"betel":[56],"quid":[57],"chewing,":[58],"fibrosis,":[62],"squamous":[65,84],"cell":[66,85],"carcinoma":[67,86],"quite":[69],"profound,":[70],"Taiwan":[73],"subcontinent":[77],"where":[78],"up":[79],"to":[80,105],"80%":[81],"associated":[88],"habit.":[91],"Epidemiological":[92],"studies":[93],"have":[94],"shown":[95],"rate":[98],"transformation":[101],"ranges":[102],"from":[103],"3":[104],"19%.":[106]},"counts_by_year":[{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":2},{"year":2020,"cited_by_count":5},{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":1},{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":4}],"updated_date":"2026-11-13T13:42:25.865203","created_date":"2016-06-24T00:00:00"}