{"id":"https://openalex.org/W1970307472","doi":"https://doi.org/10.1007/s00262-009-0738-z","title":"Identification of a broad coverage HLA-DR degenerate epitope pool derived from carcinoembryonic antigen","display_name":"Identification of a broad coverage HLA-DR degenerate epitope pool derived from carcinoembryonic antigen","publication_year":2009,"publication_date":"2009-07-20","ids":{"openalex":"https://openalex.org/W1970307472","doi":"https://doi.org/10.1007/s00262-009-0738-z","mag":"1970307472","pmid":"https://pubmed.ncbi.nlm.nih.gov/19621224","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/3667390"},"language":"en","primary_location":{"id":"doi:10.1007/s00262-009-0738-z","doi":"https://doi.org/10.1007/s00262-009-0738-z","is_oa":false,"landing_page_url":"https://doi.org/10.1007/s00262-009-0738-z","pdf_url":null,"source":{"id":"https://openalex.org/S203303425","display_name":"Cancer Immunology Immunotherapy","issn_l":"0340-7004","issn":["0340-7004","1432-0851"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cancer Immunology, Immunotherapy","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3667390","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5036474702","display_name":"Lavakumar Karyampudi","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1330342723","display_name":"Mayo Clinic","ror":"https://ror.org/02qp3tb03","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330342723"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Lavakumar Karyampudi","raw_affiliation_strings":["Department of Immunology, College of Medicine, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA","Department of Immunology, College of Medicine, Mayo Clinic, Rochester, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Immunology, College of Medicine, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA","institution_ids":["https://openalex.org/I1330342723"]},{"raw_affiliation_string":"Department of Immunology, College of Medicine, Mayo Clinic, Rochester, USA","institution_ids":["https://openalex.org/I1330342723"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5027976630","display_name":"Christopher J. Krco","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1330342723","display_name":"Mayo Clinic","ror":"https://ror.org/02qp3tb03","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330342723"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Christopher J. Krco","raw_affiliation_strings":["Department of Immunology, College of Medicine, Mayo Clinic, 342C Guggenheim, 200 First St. SW, Rochester, MN, 55905, USA","Department of Immunology, College of Medicine, Mayo Clinic, Rochester, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Immunology, College of Medicine, Mayo Clinic, 342C Guggenheim, 200 First St. SW, Rochester, MN, 55905, USA","institution_ids":["https://openalex.org/I1330342723"]},{"raw_affiliation_string":"Department of Immunology, College of Medicine, Mayo Clinic, Rochester, USA","institution_ids":["https://openalex.org/I1330342723"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5065524254","display_name":"Kimberly R. Kalli","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1330342723","display_name":"Mayo Clinic","ror":"https://ror.org/02qp3tb03","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330342723"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Kimberly R. Kalli","raw_affiliation_strings":["Department of Oncology, Mayo Clinic, Rochester, MN, 55905, USA","Department of Oncology, Mayo Clinic, Rochester, USA;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Oncology, Mayo Clinic, Rochester, MN, 55905, USA","institution_ids":["https://openalex.org/I1330342723"]},{"raw_affiliation_string":"Department of Oncology, Mayo Clinic, Rochester, USA;","institution_ids":["https://openalex.org/I1330342723"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5065454745","display_name":"Courtney L. Erskine","orcid":"https://orcid.org/0000-0001-8873-1542","observed_orcids":["https://orcid.org/0000-0001-8873-1542"]},"institutions":[{"id":"https://openalex.org/I1330342723","display_name":"Mayo Clinic","ror":"https://ror.org/02qp3tb03","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330342723"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Courtney L. Erskine","raw_affiliation_strings":["Department of Immunology, College of Medicine, Mayo Clinic, 342C Guggenheim, 200 First St. SW, Rochester, MN, 55905, USA","Department of Immunology, College of Medicine, Mayo Clinic, Rochester, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Immunology, College of Medicine, Mayo Clinic, 342C Guggenheim, 200 First St. SW, Rochester, MN, 55905, USA","institution_ids":["https://openalex.org/I1330342723"]},{"raw_affiliation_string":"Department of Immunology, College of Medicine, Mayo Clinic, Rochester, USA","institution_ids":["https://openalex.org/I1330342723"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5005798440","display_name":"Lynn C. Hartmann","orcid":"https://orcid.org/0000-0002-5931-7876","observed_orcids":["https://orcid.org/0000-0002-5931-7876"]},"institutions":[{"id":"https://openalex.org/I1330342723","display_name":"Mayo Clinic","ror":"https://ror.org/02qp3tb03","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330342723"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Lynn C. Hartmann","raw_affiliation_strings":["Department of Oncology, Mayo Clinic, Rochester, MN, 55905, USA","Department of Oncology, Mayo Clinic, Rochester, USA;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Oncology, Mayo Clinic, Rochester, MN, 55905, USA","institution_ids":["https://openalex.org/I1330342723"]},{"raw_affiliation_string":"Department of Oncology, Mayo Clinic, Rochester, USA;","institution_ids":["https://openalex.org/I1330342723"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5066494784","display_name":"Karin M. Goodman","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1330342723","display_name":"Mayo Clinic","ror":"https://ror.org/02qp3tb03","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330342723"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Karin Goodman","raw_affiliation_strings":["Department of Oncology, Mayo Clinic, Rochester, MN, 55905, USA","Department of Oncology, Mayo Clinic, Rochester, USA;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Oncology, Mayo Clinic, Rochester, MN, 55905, USA","institution_ids":["https://openalex.org/I1330342723"]},{"raw_affiliation_string":"Department of Oncology, Mayo Clinic, Rochester, USA;","institution_ids":["https://openalex.org/I1330342723"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5083904553","display_name":"James N. Ingle","orcid":"https://orcid.org/0000-0003-1257-7731","observed_orcids":["https://orcid.org/0000-0003-1257-7731"]},"institutions":[{"id":"https://openalex.org/I1330342723","display_name":"Mayo Clinic","ror":"https://ror.org/02qp3tb03","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330342723"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"James N. Ingle","raw_affiliation_strings":["Department of Oncology, Mayo Clinic, Rochester, MN, 55905, USA","Department of Oncology, Mayo Clinic, Rochester, USA;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Oncology, Mayo Clinic, Rochester, MN, 55905, USA","institution_ids":["https://openalex.org/I1330342723"]},{"raw_affiliation_string":"Department of Oncology, Mayo Clinic, Rochester, USA;","institution_ids":["https://openalex.org/I1330342723"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5059417970","display_name":"Matthew John Maurer","orcid":"https://orcid.org/0000-0002-1867-0526","observed_orcids":["https://orcid.org/0000-0002-1867-0526"]},"institutions":[{"id":"https://openalex.org/I1330342723","display_name":"Mayo Clinic","ror":"https://ror.org/02qp3tb03","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330342723"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Matthew J. Maurer","raw_affiliation_strings":["Department of Health Sciences Research, Mayo Clinic, Rochester, MN, 55905, USA","Department of Health Sciences Research, Mayo Clinic, Rochester, USA#TAB#"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Health Sciences Research, Mayo Clinic, Rochester, MN, 55905, USA","institution_ids":["https://openalex.org/I1330342723"]},{"raw_affiliation_string":"Department of Health Sciences Research, Mayo Clinic, Rochester, USA#TAB#","institution_ids":["https://openalex.org/I1330342723"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5080600800","display_name":"Aziza Nassar","orcid":"https://orcid.org/0000-0002-6678-9329","observed_orcids":["https://orcid.org/0000-0002-6678-9329"]},"institutions":[{"id":"https://openalex.org/I1330342723","display_name":"Mayo Clinic","ror":"https://ror.org/02qp3tb03","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330342723"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Aziza Nassar","raw_affiliation_strings":["Department of Anatomic Pathology, Mayo Clinic, Rochester, MN, 55905, USA","Department of Anatomic Pathology, Mayo Clinic, Rochester, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Anatomic Pathology, Mayo Clinic, Rochester, MN, 55905, USA","institution_ids":["https://openalex.org/I1330342723"]},{"raw_affiliation_string":"Department of Anatomic Pathology, Mayo Clinic, Rochester, USA","institution_ids":["https://openalex.org/I1330342723"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Chao Yu","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1330342723","display_name":"Mayo Clinic","ror":"https://ror.org/02qp3tb03","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330342723"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Chao Yu","raw_affiliation_strings":["Department of Immunology, College of Medicine, Mayo Clinic, 342C Guggenheim, 200 First St. SW, Rochester, MN, 55905, USA","Department of Immunology, College of Medicine, Mayo Clinic, Rochester, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Immunology, College of Medicine, Mayo Clinic, 342C Guggenheim, 200 First St. SW, Rochester, MN, 55905, USA","institution_ids":["https://openalex.org/I1330342723"]},{"raw_affiliation_string":"Department of Immunology, College of Medicine, Mayo Clinic, Rochester, USA","institution_ids":["https://openalex.org/I1330342723"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5039848435","display_name":"Mary Lenora Disis","orcid":"https://orcid.org/0000-0001-7653-4648","observed_orcids":["https://orcid.org/0000-0001-7653-4648"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Mary L. Disis","raw_affiliation_strings":["Tumor Vaccine Group, Center for Translational Medicine in Women\u2019s Health, Seattle, WA, 98195, USA","Center for Translational Medicine in Women\u2019s Health"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Tumor Vaccine Group, Center for Translational Medicine in Women\u2019s Health, Seattle, WA, 98195, USA","institution_ids":[]},{"raw_affiliation_string":"Center for Translational Medicine in Women\u2019s Health","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111728925","display_name":"Peter J. Wettstein","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1330342723","display_name":"Mayo Clinic","ror":"https://ror.org/02qp3tb03","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330342723"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Peter J. Wettstein","raw_affiliation_strings":["Department of Immunology, College of Medicine, Mayo Clinic, 342C Guggenheim, 200 First St. SW, Rochester, MN, 55905, USA","Department of Immunology, College of Medicine, Mayo Clinic, Rochester, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Immunology, College of Medicine, Mayo Clinic, 342C Guggenheim, 200 First St. SW, Rochester, MN, 55905, USA","institution_ids":["https://openalex.org/I1330342723"]},{"raw_affiliation_string":"Department of Immunology, College of Medicine, Mayo Clinic, Rochester, USA","institution_ids":["https://openalex.org/I1330342723"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5056430250","display_name":"John D. Fikes","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"John D. Fikes","raw_affiliation_strings":["Pharmexa-Epimmune, Inc., San Diego, CA, 92121, USA","Pharmexa-Epimmune, Inc"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Pharmexa-Epimmune, Inc., San Diego, CA, 92121, USA","institution_ids":[]},{"raw_affiliation_string":"Pharmexa-Epimmune, Inc","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5073677839","display_name":"Melanie Beebe","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Melanie Beebe","raw_affiliation_strings":["Pharmexa-Epimmune, Inc., San Diego, CA, 92121, USA","Pharmexa-Epimmune, Inc., San Diego, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Pharmexa-Epimmune, Inc., San Diego, CA, 92121, USA","institution_ids":[]},{"raw_affiliation_string":"Pharmexa-Epimmune, Inc., San Diego, USA","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111630865","display_name":"Glenn Y. Ishioka","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Glenn Ishioka","raw_affiliation_strings":["Pharmexa-Epimmune, Inc., San Diego, CA, 92121, USA","Pharmexa-Epimmune, Inc"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Pharmexa-Epimmune, Inc., San Diego, CA, 92121, USA","institution_ids":[]},{"raw_affiliation_string":"Pharmexa-Epimmune, Inc","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5031005364","display_name":"Keith L. Knutson","orcid":"https://orcid.org/0000-0001-9932-4467","observed_orcids":["https://orcid.org/0000-0001-9932-4467"]},"institutions":[{"id":"https://openalex.org/I1330342723","display_name":"Mayo Clinic","ror":"https://ror.org/02qp3tb03","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330342723"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Keith L. Knutson","raw_affiliation_strings":["Department of Immunology, College of Medicine, Mayo Clinic, 342C Guggenheim, 200 First St. SW, Rochester, MN, 55905, USA","Department of Immunology, College of Medicine, Mayo Clinic, Rochester, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Immunology, College of Medicine, Mayo Clinic, 342C Guggenheim, 200 First St. SW, Rochester, MN, 55905, USA","institution_ids":["https://openalex.org/I1330342723"]},{"raw_affiliation_string":"Department of Immunology, College of Medicine, Mayo Clinic, Rochester, USA","institution_ids":["https://openalex.org/I1330342723"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5031005364"],"corresponding_institution_ids":["https://openalex.org/I1330342723"],"apc_list":{"value":4590,"currency":"USD","value_usd":4590},"apc_paid":null,"fwci":0.5751,"has_fulltext":false,"cited_by_count":13,"citation_normalized_percentile":{"value":0.67802867,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":96},"biblio":{"volume":"59","issue":"1","first_page":"161","last_page":"171"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10580","display_name":"Immunotherapy and Immune Responses","score":0.711899995803833,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10580","display_name":"Immunotherapy and Immune Responses","score":0.711899995803833,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12576","display_name":"vaccines and immunoinformatics approaches","score":0.2815000116825104,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10158","display_name":"Cancer Immunotherapy and Biomarkers","score":0.0032999999821186066,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/carcinoembryonic-antigen","display_name":"carcinoembryonic antigen","score":0.996999979019165},{"id":"https://openalex.org/keywords/cd4-t-cell-immunity","display_name":"CD4+ T cell immunity","score":0.8220000267028809},{"id":"https://openalex.org/keywords/tumor-antigens","display_name":"tumor antigens","score":0.4230000078678131},{"id":"https://openalex.org/keywords/epitope-prediction","display_name":"epitope prediction","score":0.7620000243186951},{"id":"https://openalex.org/keywords/peptide-binding-affinity","display_name":"peptide binding affinity","score":0.4650000035762787},{"id":"https://openalex.org/keywords/breast-cancer","display_name":"breast cancer","score":0.7950000166893005},{"id":"https://openalex.org/keywords/ovarian-cancer","display_name":"ovarian cancer","score":1.0},{"id":"https://openalex.org/keywords/antigen-processing","display_name":"antigen processing","score":0.5550000071525574},{"id":"https://openalex.org/keywords/cancer-immunotherapy","display_name":"cancer immunotherapy","score":0.6349999904632568}],"concepts":[{"id":"https://openalex.org/C195616568","wikidata":"https://www.wikidata.org/wiki/Q128711","display_name":"Epitope","level":3,"score":0.9431253671646118},{"id":"https://openalex.org/C2777387746","wikidata":"https://www.wikidata.org/wiki/Q769706","display_name":"Carcinoembryonic antigen","level":3,"score":0.7269136905670166},{"id":"https://openalex.org/C2779053233","wikidata":"https://www.wikidata.org/wiki/Q731235","display_name":"ELISPOT","level":4,"score":0.7177008390426636},{"id":"https://openalex.org/C147483822","wikidata":"https://www.wikidata.org/wiki/Q103537","display_name":"Antigen","level":2,"score":0.5536398887634277},{"id":"https://openalex.org/C8891405","wikidata":"https://www.wikidata.org/wiki/Q1059","display_name":"Immune system","level":2,"score":0.5425518155097961},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.48562899231910706},{"id":"https://openalex.org/C188280979","wikidata":"https://www.wikidata.org/wiki/Q911125","display_name":"Human leukocyte antigen","level":3,"score":0.4730895161628723},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.44563719630241394},{"id":"https://openalex.org/C2776090121","wikidata":"https://www.wikidata.org/wiki/Q193529","display_name":"T cell","level":3,"score":0.3533371090888977},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.3254696726799011},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.239286869764328},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.06559905409812927}],"mesh":[{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000939","descriptor_name":"Epitopes","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001943","descriptor_name":"Breast Neoplasms","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D002272","descriptor_name":"Carcinoembryonic Antigen","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006684","descriptor_name":"HLA-DR Antigens","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010051","descriptor_name":"Ovarian Neoplasms","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015496","descriptor_name":"CD4-Positive T-Lymphocytes","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.1007/s00262-009-0738-z","doi":"https://doi.org/10.1007/s00262-009-0738-z","is_oa":false,"landing_page_url":"https://doi.org/10.1007/s00262-009-0738-z","pdf_url":null,"source":{"id":"https://openalex.org/S203303425","display_name":"Cancer Immunology Immunotherapy","issn_l":"0340-7004","issn":["0340-7004","1432-0851"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cancer Immunology, Immunotherapy","raw_type":"journal-article"},{"id":"pmh:oai:europepmc.org:2662421","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3667390","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:3667390","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3667390","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cancer Immunol Immunother","raw_type":"Text"},{"id":"pmid:19621224","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/19621224","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cancer immunology, immunotherapy : CII","raw_type":"Journal Article"}],"best_oa_location":{"id":"pmh:oai:europepmc.org:2662421","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3667390","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.9763000011444092,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G10684862","display_name":"Ex vivo expansion of HER-2/neu specific T helper cells","funder_award_id":"K01CA100764","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"},{"id":"https://openalex.org/G163746209","display_name":null,"funder_award_id":"R41-CA107590-01","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"},{"id":"https://openalex.org/G4081782440","display_name":"A Cancer Vaccine for Ovarian and Breast Cancer","funder_award_id":"R41CA107590","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"},{"id":"https://openalex.org/G8549715945","display_name":"Lymphoma Specialized Program of Research Excellence (SPORE) in Human Cancer","funder_award_id":"P50CA097274","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"},{"id":"https://openalex.org/G9000881388","display_name":"Paul Calabresi Program in Clinical/Translational Research at Mayo Clinic","funder_award_id":"K12CA090628","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"},{"id":"https://openalex.org/G9000912503","display_name":"Mayo Clinic Breast Cancer SPORE","funder_award_id":"P50CA116201","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"}],"funders":[{"id":"https://openalex.org/F4320337351","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":42,"referenced_works":["https://openalex.org/W1482905954","https://openalex.org/W1490290317","https://openalex.org/W1874580585","https://openalex.org/W1926859278","https://openalex.org/W1944657476","https://openalex.org/W1956173684","https://openalex.org/W1963628803","https://openalex.org/W1968592882","https://openalex.org/W1975654444","https://openalex.org/W1989402502","https://openalex.org/W2009648532","https://openalex.org/W2016263146","https://openalex.org/W2016671320","https://openalex.org/W2020990387","https://openalex.org/W2028000100","https://openalex.org/W2028852768","https://openalex.org/W2035194338","https://openalex.org/W2035878292","https://openalex.org/W2057427370","https://openalex.org/W2071369468","https://openalex.org/W2072865691","https://openalex.org/W2083379652","https://openalex.org/W2095575390","https://openalex.org/W2096190466","https://openalex.org/W2100319980","https://openalex.org/W2103188564","https://openalex.org/W2120888343","https://openalex.org/W2130261432","https://openalex.org/W2135951804","https://openalex.org/W2137940095","https://openalex.org/W2146747550","https://openalex.org/W2146934263","https://openalex.org/W2148177811","https://openalex.org/W2148564980","https://openalex.org/W2154200910","https://openalex.org/W2154203858","https://openalex.org/W2159116335","https://openalex.org/W2160344066","https://openalex.org/W2161425324","https://openalex.org/W2166458832","https://openalex.org/W2170055192","https://openalex.org/W2171515055"],"related_works":["https://openalex.org/W7099314550","https://openalex.org/W2100319980","https://openalex.org/W1843594557","https://openalex.org/W2135951804","https://openalex.org/W2057427370","https://openalex.org/W2161425324","https://openalex.org/W2166458832","https://openalex.org/W1981417548","https://openalex.org/W2043616870","https://openalex.org/W2031901919"],"abstract_inverted_index":null,"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":2},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":2},{"year":2018,"cited_by_count":1},{"year":2013,"cited_by_count":1},{"year":2012,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}