{"id":"https://openalex.org/W1970240448","doi":"https://doi.org/10.1039/c3tb20806k","title":"Morphology dependent photosensitization and formation of singlet oxygen (1\u0394g) by gold and silver nanoparticles and its application in cancer treatment","display_name":"Morphology dependent photosensitization and formation of singlet oxygen (1\u0394g) by gold and silver nanoparticles and its application in cancer treatment","publication_year":2013,"publication_date":"2013-01-01","ids":{"openalex":"https://openalex.org/W1970240448","doi":"https://doi.org/10.1039/c3tb20806k","mag":"1970240448","pmid":"https://pubmed.ncbi.nlm.nih.gov/32261111"},"language":"en","primary_location":{"id":"doi:10.1039/c3tb20806k","doi":"https://doi.org/10.1039/c3tb20806k","is_oa":false,"landing_page_url":"https://doi.org/10.1039/c3tb20806k","pdf_url":null,"source":{"id":"https://openalex.org/S2479884170","display_name":"Journal of Materials Chemistry B","issn_l":"2050-750X","issn":["2050-750X","2050-7518"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320556","host_organization_name":"Royal Society of Chemistry","host_organization_lineage":["https://openalex.org/P4310320556"],"host_organization_lineage_names":["Royal Society of Chemistry"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Materials Chemistry B","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5032776915","display_name":"Raviraj Vankayala","orcid":"https://orcid.org/0000-0002-4661-066X","observed_orcids":["https://orcid.org/0000-0002-4661-066X"]},"institutions":[{"id":"https://openalex.org/I25846049","display_name":"National Tsing Hua University","ror":"https://ror.org/00zdnkx70","country_code":"TW","type":"education","lineage":["https://openalex.org/I25846049"]}],"countries":["TW"],"is_corresponding":false,"raw_author_name":"Raviraj Vankayala","raw_affiliation_strings":["Department of Chemistry, National Tsing Hua University, Hsinchu, Taiwan 30013. kchwang@mx.nthu.edu.tw","Department of Chemistry , National Tsing Hua University , Hsinchu , Taiwan 30013"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry, National Tsing Hua University, Hsinchu, Taiwan 30013. kchwang@mx.nthu.edu.tw","institution_ids":["https://openalex.org/I25846049"]},{"raw_affiliation_string":"Department of Chemistry , National Tsing Hua University , Hsinchu , Taiwan 30013","institution_ids":["https://openalex.org/I25846049"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5090523366","display_name":"Chien\u2010Lin Kuo","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I25846049","display_name":"National Tsing Hua University","ror":"https://ror.org/00zdnkx70","country_code":"TW","type":"education","lineage":["https://openalex.org/I25846049"]}],"countries":["TW"],"is_corresponding":false,"raw_author_name":"Chien-Lin Kuo","raw_affiliation_strings":["Department of Chemistry, National Tsing Hua University, Hsinchu, Taiwan 30013"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry, National Tsing Hua University, Hsinchu, Taiwan 30013","institution_ids":["https://openalex.org/I25846049"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5087912087","display_name":"Arunachalam Sagadevan","orcid":"https://orcid.org/0000-0001-9486-1706","observed_orcids":["https://orcid.org/0000-0001-9486-1706","https://orcid.org/0000-0001-5480-7756"]},"institutions":[{"id":"https://openalex.org/I25846049","display_name":"National Tsing Hua University","ror":"https://ror.org/00zdnkx70","country_code":"TW","type":"education","lineage":["https://openalex.org/I25846049"]}],"countries":["TW"],"is_corresponding":false,"raw_author_name":"Arunachalam Sagadevan","raw_affiliation_strings":["Department of Chemistry, National Tsing Hua University, Hsinchu, Taiwan 30013"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry, National Tsing Hua University, Hsinchu, Taiwan 30013","institution_ids":["https://openalex.org/I25846049"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Po-Hung Chen","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I25846049","display_name":"National Tsing Hua University","ror":"https://ror.org/00zdnkx70","country_code":"TW","type":"education","lineage":["https://openalex.org/I25846049"]}],"countries":["TW"],"is_corresponding":false,"raw_author_name":"Po-Hung Chen","raw_affiliation_strings":["Department of Chemistry, National Tsing Hua University, Hsinchu, Taiwan 30013"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry, National Tsing Hua University, Hsinchu, Taiwan 30013","institution_ids":["https://openalex.org/I25846049"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5071055947","display_name":"Chi\u2010Shiun Chiang","orcid":"https://orcid.org/0000-0002-2581-4129","observed_orcids":["https://orcid.org/0000-0002-2581-4129"]},"institutions":[{"id":"https://openalex.org/I25846049","display_name":"National Tsing Hua University","ror":"https://ror.org/00zdnkx70","country_code":"TW","type":"education","lineage":["https://openalex.org/I25846049"]}],"countries":["TW"],"is_corresponding":false,"raw_author_name":"Chi-Shiun Chiang","raw_affiliation_strings":["Department of Biomedical Engineering and Environmental Sciences, National Tsing Hua University, Hsinchu, Taiwan 30013"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biomedical Engineering and Environmental Sciences, National Tsing Hua University, Hsinchu, Taiwan 30013","institution_ids":["https://openalex.org/I25846049"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5054920429","display_name":"Kuo Chu Hwang","orcid":"https://orcid.org/0000-0003-1814-9869","observed_orcids":["https://orcid.org/0000-0003-1814-9869"]},"institutions":[{"id":"https://openalex.org/I25846049","display_name":"National Tsing Hua University","ror":"https://ror.org/00zdnkx70","country_code":"TW","type":"education","lineage":["https://openalex.org/I25846049"]}],"countries":["TW"],"is_corresponding":true,"raw_author_name":"Kuo Chu Hwang","raw_affiliation_strings":["Department of Chemistry, National Tsing Hua University, Hsinchu, Taiwan 30013"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry, National Tsing Hua University, Hsinchu, Taiwan 30013","institution_ids":["https://openalex.org/I25846049"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5054920429"],"corresponding_institution_ids":["https://openalex.org/I25846049"],"apc_list":null,"apc_paid":null,"fwci":4.0169,"has_fulltext":false,"cited_by_count":105,"citation_normalized_percentile":{"value":0.94631767,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":94,"max":100},"biblio":{"volume":"1","issue":"35","first_page":"4379","last_page":"4379"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10131","display_name":"Gold and Silver Nanoparticles Synthesis and Applications","score":0.8515999913215637,"subfield":{"id":"https://openalex.org/subfields/2504","display_name":"Electronic, Optical and Magnetic Materials"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10131","display_name":"Gold and Silver Nanoparticles Synthesis and Applications","score":0.8515999913215637,"subfield":{"id":"https://openalex.org/subfields/2504","display_name":"Electronic, Optical and Magnetic Materials"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10957","display_name":"Photodynamic Therapy Research Studies","score":0.07010000199079514,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10782","display_name":"Nanoplatforms for cancer theranostics","score":0.056299999356269836,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/singlet-oxygen","display_name":"singlet oxygen","score":0.9259999990463257},{"id":"https://openalex.org/keywords/photosensitization","display_name":"photosensitization","score":0.9480000138282776},{"id":"https://openalex.org/keywords/gold-nanoparticles","display_name":"gold nanoparticles","score":0.7239999771118164},{"id":"https://openalex.org/keywords/silver-nanoparticles","display_name":"silver nanoparticles","score":1.0},{"id":"https://openalex.org/keywords/nanoparticle-morphology","display_name":"nanoparticle morphology","score":0.890999972820282},{"id":"https://openalex.org/keywords/surface-plasmon-resonance","display_name":"surface plasmon resonance","score":0.9900000095367432},{"id":"https://openalex.org/keywords/gold-nanorods","display_name":"gold nanorods","score":0.8659999966621399},{"id":"https://openalex.org/keywords/photodynamic-therapy","display_name":"photodynamic therapy","score":0.6890000104904175},{"id":"https://openalex.org/keywords/photothermal-therapy","display_name":"photothermal therapy","score":0.9629999995231628},{"id":"https://openalex.org/keywords/reactive-oxygen-species","display_name":"reactive oxygen species","score":0.8939999938011169},{"id":"https://openalex.org/keywords/cancer-therapy","display_name":"cancer therapy","score":0.7080000042915344},{"id":"https://openalex.org/keywords/near-infrared-light","display_name":"near-infrared light","score":0.6579999923706055}],"concepts":[{"id":"https://openalex.org/C2777516457","wikidata":"https://www.wikidata.org/wiki/Q2413613","display_name":"Singlet oxygen","level":3,"score":0.9473843574523926},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.6896935105323792},{"id":"https://openalex.org/C75473681","wikidata":"https://www.wikidata.org/wiki/Q188651","display_name":"Photochemistry","level":1,"score":0.6784024834632874},{"id":"https://openalex.org/C104819515","wikidata":"https://www.wikidata.org/wiki/Q900961","display_name":"Colloidal gold","level":3,"score":0.6030566692352295},{"id":"https://openalex.org/C2781323092","wikidata":"https://www.wikidata.org/wiki/Q1428072","display_name":"Photodynamic therapy","level":2,"score":0.5922610759735107},{"id":"https://openalex.org/C126201875","wikidata":"https://www.wikidata.org/wiki/Q2684948","display_name":"Nanorod","level":2,"score":0.5841439962387085},{"id":"https://openalex.org/C31499863","wikidata":"https://www.wikidata.org/wiki/Q905762","display_name":"Silver nanoparticle","level":3,"score":0.5736382603645325},{"id":"https://openalex.org/C182606246","wikidata":"https://www.wikidata.org/wiki/Q7187926","display_name":"Photothermal therapy","level":2,"score":0.5233032703399658},{"id":"https://openalex.org/C106847996","wikidata":"https://www.wikidata.org/wiki/Q898756","display_name":"Surface plasmon resonance","level":3,"score":0.4930069148540497},{"id":"https://openalex.org/C155672457","wikidata":"https://www.wikidata.org/wiki/Q61231","display_name":"Nanoparticle","level":2,"score":0.46915021538734436},{"id":"https://openalex.org/C2776217527","wikidata":"https://www.wikidata.org/wiki/Q944828","display_name":"Sensitization","level":2,"score":0.45563119649887085},{"id":"https://openalex.org/C171250308","wikidata":"https://www.wikidata.org/wiki/Q11468","display_name":"Nanotechnology","level":1,"score":0.4036710858345032},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.27932947874069214},{"id":"https://openalex.org/C540031477","wikidata":"https://www.wikidata.org/wiki/Q629","display_name":"Oxygen","level":2,"score":0.2550065517425537},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.07578292489051819},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.050300776958465576},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.0}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.1039/c3tb20806k","doi":"https://doi.org/10.1039/c3tb20806k","is_oa":false,"landing_page_url":"https://doi.org/10.1039/c3tb20806k","pdf_url":null,"source":{"id":"https://openalex.org/S2479884170","display_name":"Journal of Materials Chemistry B","issn_l":"2050-750X","issn":["2050-750X","2050-7518"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320556","host_organization_name":"Royal Society of Chemistry","host_organization_lineage":["https://openalex.org/P4310320556"],"host_organization_lineage_names":["Royal Society of Chemistry"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Materials Chemistry B","raw_type":"journal-article"},{"id":"pmid:32261111","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/32261111","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of materials chemistry. B","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.7246000170707703,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":75,"referenced_works":["https://openalex.org/W110531226","https://openalex.org/W1555450157","https://openalex.org/W1596848781","https://openalex.org/W1903778810","https://openalex.org/W1965399283","https://openalex.org/W1966455273","https://openalex.org/W1966933349","https://openalex.org/W1967215527","https://openalex.org/W1969198868","https://openalex.org/W1979140965","https://openalex.org/W1980495221","https://openalex.org/W1985233124","https://openalex.org/W1988379415","https://openalex.org/W1997883658","https://openalex.org/W2004614620","https://openalex.org/W2006882472","https://openalex.org/W2008748363","https://openalex.org/W2009988263","https://openalex.org/W2010287396","https://openalex.org/W2014432829","https://openalex.org/W2017290810","https://openalex.org/W2017806602","https://openalex.org/W2018626703","https://openalex.org/W2022645259","https://openalex.org/W2025295644","https://openalex.org/W2028539204","https://openalex.org/W2029172950","https://openalex.org/W2035098006","https://openalex.org/W2035864800","https://openalex.org/W2039508447","https://openalex.org/W2039813734","https://openalex.org/W2040958578","https://openalex.org/W2041801757","https://openalex.org/W2043418539","https://openalex.org/W2044560021","https://openalex.org/W2045365412","https://openalex.org/W2053194254","https://openalex.org/W2059410872","https://openalex.org/W2061820211","https://openalex.org/W2067160237","https://openalex.org/W2067389663","https://openalex.org/W2069623688","https://openalex.org/W2072298860","https://openalex.org/W2075483486","https://openalex.org/W2076849967","https://openalex.org/W2077351767","https://openalex.org/W2078722993","https://openalex.org/W2080374105","https://openalex.org/W2080376276","https://openalex.org/W2083073535","https://openalex.org/W2086226419","https://openalex.org/W2086696748","https://openalex.org/W2099966615","https://openalex.org/W2100903105","https://openalex.org/W2112227276","https://openalex.org/W2121842066","https://openalex.org/W2124531971","https://openalex.org/W2125107358","https://openalex.org/W2131721476","https://openalex.org/W2139683943","https://openalex.org/W2144197904","https://openalex.org/W2146677456","https://openalex.org/W2150735104","https://openalex.org/W2157901539","https://openalex.org/W2161744546","https://openalex.org/W2163982849","https://openalex.org/W2167877463","https://openalex.org/W2314025028","https://openalex.org/W2314692897","https://openalex.org/W2317373033","https://openalex.org/W2322907859","https://openalex.org/W2324575802","https://openalex.org/W2329353330","https://openalex.org/W2952943011","https://openalex.org/W3041750192"],"related_works":["https://openalex.org/W2121148713","https://openalex.org/W2993548433","https://openalex.org/W4286447753","https://openalex.org/W2796462384","https://openalex.org/W2046406176","https://openalex.org/W2146677456","https://openalex.org/W2320979350","https://openalex.org/W7098900955","https://openalex.org/W2128845258","https://openalex.org/W2884884349"],"abstract_inverted_index":{"Singlet":[0],"oxygen":[1,7,33],"is":[2,64],"a":[3,147],"very":[4,185],"important":[5],"reactive":[6],"species":[8],"(ROS)":[9],"involved":[10],"in":[11,20,160,169],"peroxidation":[12],"of":[13,25,45,61,70,86,104,112,118,166,192],"olefins":[14],"and":[15,59,72,84,89,98,106,202],"polymers,":[16],"as":[17,19,195],"well":[18],"clinical":[21],"photodynamic":[22,171,200],"therapy":[23,201,204],"treatments":[24],"tumors.":[26],"Previously,":[27],"it":[28],"was":[29],"reported":[30],"that":[31,57,177],"singlet":[32,62,77,121,150],"can":[34,79,123],"be":[35,80,124,154],"formed":[36],"via":[37,82,126],"sensitization":[38,58,85,102,152,164],"by":[39,95,135],"spherical":[40],"metal":[41,178],"nanoparticles":[42,108,168,179],"upon":[43],"photo-excitation":[44,127],"the":[46,68,110,116,129,138,170],"surface":[47],"plasmon":[48],"resonance":[49],"(SPR)":[50],"bands.":[51],"In":[52,115],"this":[53],"paper,":[54],"we":[55,157],"report":[56],"formation":[60],"O2":[63,78,122,151],"strongly":[65],"dependent":[66,149,163],"on":[67],"morphologies":[69,182],"gold":[71,99,107,119],"silver":[73,87,90,96,105,167],"nanostructures.":[74],"For":[75],"example,":[76],"generated":[81,125],"photo-irradiation":[83],"decahedrons":[88],"triangular":[91],"nanoplates,":[92],"but":[93,133],"not":[94,134],"nanocubes":[97],"decahedrons.":[100],"The":[101,142],"patterns":[103],"are":[109,183],"reverse":[111],"each":[113],"other.":[114],"case":[117],"nanorods,":[120],"at":[128,137],"longitudinal":[130],"SPR":[131,140],"band,":[132],"excitation":[136],"transverse":[139],"band.":[141],"controlling":[143],"factors":[144],"for":[145,206],"such":[146],"morphology":[148,162],"will":[153],"discussed.":[155],"Furthermore,":[156],"also":[158],"demonstrate":[159],"vitro":[161],"behaviour":[165],"cancer":[172,207],"treatment.":[173],"Our":[174],"results":[175],"indicate":[176],"with":[180,190],"certain":[181],"potentially":[184],"promising":[186],"dual":[187],"functional":[188],"nanomaterials":[189],"capabilities":[191],"simultaneously":[193],"serving":[194],"near":[196],"infrared":[197],"(NIR)":[198],"activatable":[199],"photothermal":[203],"reagents":[205],"treatments.":[208]},"counts_by_year":[{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":13},{"year":2023,"cited_by_count":4},{"year":2022,"cited_by_count":11},{"year":2021,"cited_by_count":13},{"year":2020,"cited_by_count":8},{"year":2019,"cited_by_count":5},{"year":2018,"cited_by_count":10},{"year":2017,"cited_by_count":5},{"year":2016,"cited_by_count":6},{"year":2015,"cited_by_count":15},{"year":2014,"cited_by_count":10},{"year":2013,"cited_by_count":3}],"updated_date":"2026-10-30T12:39:25.321706","created_date":"2016-06-24T00:00:00"}