{"id":"https://openalex.org/W1969952570","doi":"https://doi.org/10.1515/revneuro-2014-0028","title":"Neural mechanisms of mental fatigue","display_name":"Neural mechanisms of mental fatigue","publication_year":2014,"publication_date":"2014-01-13","ids":{"openalex":"https://openalex.org/W1969952570","doi":"https://doi.org/10.1515/revneuro-2014-0028","mag":"1969952570","pmid":"https://pubmed.ncbi.nlm.nih.gov/24926625"},"language":"en","primary_location":{"id":"doi:10.1515/revneuro-2014-0028","doi":"https://doi.org/10.1515/revneuro-2014-0028","is_oa":false,"landing_page_url":"https://doi.org/10.1515/revneuro-2014-0028","pdf_url":null,"source":{"id":"https://openalex.org/S15160710","display_name":"Reviews in the Neurosciences","issn_l":"0334-1763","issn":["0334-1763","2191-0200"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310313990","host_organization_name":"De Gruyter","host_organization_lineage":["https://openalex.org/P4310313990"],"host_organization_lineage_names":["De Gruyter"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Reviews in the Neurosciences","raw_type":"journal-article"},"volume":null,"type":"review","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5085977929","display_name":"Akira Ishii","orcid":"https://orcid.org/0000-0001-6374-4697","observed_orcids":["https://orcid.org/0000-0001-6374-4697"]},"institutions":[{"id":"https://openalex.org/I317356780","display_name":"Osaka City University","ror":"https://ror.org/02skfsw40","country_code":"JP","type":"education","lineage":["https://openalex.org/I317356780","https://openalex.org/I4387152983"]}],"countries":["JP"],"is_corresponding":true,"raw_author_name":"Akira Ishii","raw_affiliation_strings":["Department of Physiology, Osaka City University Graduate School of Medicine, 1-4-3 Asahimachi, Abeno-ku, Osaka 545-8585, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Physiology, Osaka City University Graduate School of Medicine, 1-4-3 Asahimachi, Abeno-ku, Osaka 545-8585, Japan","institution_ids":["https://openalex.org/I317356780"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5062408915","display_name":"Masaaki Tanaka","orcid":"https://orcid.org/0000-0003-3599-663X","observed_orcids":["https://orcid.org/0000-0003-3599-663X"]},"institutions":[{"id":"https://openalex.org/I317356780","display_name":"Osaka City University","ror":"https://ror.org/02skfsw40","country_code":"JP","type":"education","lineage":["https://openalex.org/I317356780","https://openalex.org/I4387152983"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Masaaki Tanaka","raw_affiliation_strings":["Department of Physiology, Osaka City University Graduate School of Medicine, 1-4-3 Asahimachi, Abeno-ku, Osaka 545-8585, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Physiology, Osaka City University Graduate School of Medicine, 1-4-3 Asahimachi, Abeno-ku, Osaka 545-8585, Japan","institution_ids":["https://openalex.org/I317356780"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5037300111","display_name":"Yasuyoshi Watanabe","orcid":"https://orcid.org/0000-0003-2623-5599","observed_orcids":["https://orcid.org/0000-0003-2623-5599"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Yasuyoshi Watanabe","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5085977929"],"corresponding_institution_ids":["https://openalex.org/I317356780"],"apc_list":{"value":2400,"currency":"EUR","value_usd":2712},"apc_paid":null,"fwci":0.6523,"has_fulltext":false,"cited_by_count":237,"citation_normalized_percentile":{"value":0.57029703,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":94,"max":100},"biblio":{"volume":"0","issue":"0","first_page":"469","last_page":"79"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11373","display_name":"Sleep and Work-Related Fatigue","score":0.9345999956130981,"subfield":{"id":"https://openalex.org/subfields/3205","display_name":"Experimental and Cognitive Psychology"},"field":{"id":"https://openalex.org/fields/32","display_name":"Psychology"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}},"topics":[{"id":"https://openalex.org/T11373","display_name":"Sleep and Work-Related Fatigue","score":0.9345999956130981,"subfield":{"id":"https://openalex.org/subfields/3205","display_name":"Experimental and Cognitive Psychology"},"field":{"id":"https://openalex.org/fields/32","display_name":"Psychology"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}},{"id":"https://openalex.org/T10042","display_name":"Neural and Behavioral Psychology Studies","score":0.024000000208616257,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10525","display_name":"Human-Automation Interaction and Safety","score":0.017100000753998756,"subfield":{"id":"https://openalex.org/subfields/3207","display_name":"Social Psychology"},"field":{"id":"https://openalex.org/fields/32","display_name":"Psychology"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/mental-fatigue","display_name":"mental fatigue","score":1.0},{"id":"https://openalex.org/keywords/neural-mechanisms","display_name":"neural mechanisms","score":0.968999981880188},{"id":"https://openalex.org/keywords/cognitive-task-performance","display_name":"cognitive task performance","score":0.8550000190734863},{"id":"https://openalex.org/keywords/cognitive-function","display_name":"cognitive function","score":0.5249999761581421},{"id":"https://openalex.org/keywords/brain-regions","display_name":"brain regions","score":0.39899998903274536}],"concepts":[{"id":"https://openalex.org/C2982735371","wikidata":"https://www.wikidata.org/wiki/Q9690","display_name":"Mental fatigue","level":2,"score":0.8084368705749512},{"id":"https://openalex.org/C169900460","wikidata":"https://www.wikidata.org/wiki/Q2200417","display_name":"Cognition","level":2,"score":0.6884322166442871},{"id":"https://openalex.org/C2780451532","wikidata":"https://www.wikidata.org/wiki/Q759676","display_name":"Task (project management)","level":2,"score":0.6618151068687439},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.5809592604637146},{"id":"https://openalex.org/C180747234","wikidata":"https://www.wikidata.org/wiki/Q23373","display_name":"Cognitive psychology","level":1,"score":0.5067842602729797},{"id":"https://openalex.org/C1337776","wikidata":"https://www.wikidata.org/wiki/Q1941955","display_name":"Facilitation","level":2,"score":0.4569367468357086},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.3159789443016052},{"id":"https://openalex.org/C70410870","wikidata":"https://www.wikidata.org/wiki/Q199906","display_name":"Clinical psychology","level":1,"score":0.19473600387573242},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.11091330647468567},{"id":"https://openalex.org/C201995342","wikidata":"https://www.wikidata.org/wiki/Q682496","display_name":"Systems engineering","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D001921","descriptor_name":"Brain","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":true},{"descriptor_ui":"D003071","descriptor_name":"Cognition","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005222","descriptor_name":"Mental Fatigue","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009433","descriptor_name":"Neural Inhibition","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1515/revneuro-2014-0028","doi":"https://doi.org/10.1515/revneuro-2014-0028","is_oa":false,"landing_page_url":"https://doi.org/10.1515/revneuro-2014-0028","pdf_url":null,"source":{"id":"https://openalex.org/S15160710","display_name":"Reviews in the Neurosciences","issn_l":"0334-1763","issn":["0334-1763","2191-0200"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310313990","host_organization_name":"De Gruyter","host_organization_lineage":["https://openalex.org/P4310313990"],"host_organization_lineage_names":["De Gruyter"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Reviews in the Neurosciences","raw_type":"journal-article"},{"id":"pmid:24926625","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/24926625","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Reviews in the neurosciences","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.8048999905586243,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320320912","display_name":"Ministry of Education, Culture, Sports, Science and Technology","ror":"https://ror.org/048rj2z13"},{"id":"https://openalex.org/F4320334764","display_name":"Japan Society for the Promotion of Science","ror":"https://ror.org/00hhkn466"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":106,"referenced_works":["https://openalex.org/W13437719","https://openalex.org/W76648564","https://openalex.org/W600006647","https://openalex.org/W1589199242","https://openalex.org/W1603307924","https://openalex.org/W1787747564","https://openalex.org/W1884136276","https://openalex.org/W1942657002","https://openalex.org/W1965053081","https://openalex.org/W1967439245","https://openalex.org/W1969180476","https://openalex.org/W1969539813","https://openalex.org/W1971990609","https://openalex.org/W1972075157","https://openalex.org/W1975120642","https://openalex.org/W1976202125","https://openalex.org/W1976760862","https://openalex.org/W1978689156","https://openalex.org/W1985329135","https://openalex.org/W1985715468","https://openalex.org/W1987777830","https://openalex.org/W1993296750","https://openalex.org/W1993622316","https://openalex.org/W1997198684","https://openalex.org/W1997576702","https://openalex.org/W1999329557","https://openalex.org/W2002641851","https://openalex.org/W2004868509","https://openalex.org/W2009271482","https://openalex.org/W2010767102","https://openalex.org/W2015327927","https://openalex.org/W2015762312","https://openalex.org/W2018244819","https://openalex.org/W2020636238","https://openalex.org/W2029611822","https://openalex.org/W2029874896","https://openalex.org/W2034469274","https://openalex.org/W2038879805","https://openalex.org/W2039728997","https://openalex.org/W2042010613","https://openalex.org/W2043528056","https://openalex.org/W2043809651","https://openalex.org/W2045970528","https://openalex.org/W2047541913","https://openalex.org/W2047679743","https://openalex.org/W2049052668","https://openalex.org/W2049499319","https://openalex.org/W2051926699","https://openalex.org/W2052055301","https://openalex.org/W2052499147","https://openalex.org/W2052748347","https://openalex.org/W2053889950","https://openalex.org/W2054028169","https://openalex.org/W2056811629","https://openalex.org/W2061496397","https://openalex.org/W2061561607","https://openalex.org/W2062578372","https://openalex.org/W2066598516","https://openalex.org/W2074535854","https://openalex.org/W2074583205","https://openalex.org/W2075715784","https://openalex.org/W2076808318","https://openalex.org/W2082829597","https://openalex.org/W2083018706","https://openalex.org/W2088240158","https://openalex.org/W2089493460","https://openalex.org/W2090828134","https://openalex.org/W2094795912","https://openalex.org/W2096311026","https://openalex.org/W2098287790","https://openalex.org/W2100440751","https://openalex.org/W2101608542","https://openalex.org/W2112400936","https://openalex.org/W2125109199","https://openalex.org/W2126796576","https://openalex.org/W2130594379","https://openalex.org/W2134578383","https://openalex.org/W2137594781","https://openalex.org/W2138259683","https://openalex.org/W2140265819","https://openalex.org/W2140362680","https://openalex.org/W2141183879","https://openalex.org/W2141265503","https://openalex.org/W2141309263","https://openalex.org/W2141412511","https://openalex.org/W2142823391","https://openalex.org/W2142888303","https://openalex.org/W2144789364","https://openalex.org/W2148080836","https://openalex.org/W2148209654","https://openalex.org/W2151315308","https://openalex.org/W2156552533","https://openalex.org/W2156926719","https://openalex.org/W2158976222","https://openalex.org/W2159680570","https://openalex.org/W2160660606","https://openalex.org/W2162571494","https://openalex.org/W2164641934","https://openalex.org/W2167010919","https://openalex.org/W2167652505","https://openalex.org/W2168861424","https://openalex.org/W2171140194","https://openalex.org/W2172257310","https://openalex.org/W2231083963","https://openalex.org/W2504536668","https://openalex.org/W7073875074"],"related_works":["https://openalex.org/W4282937189","https://openalex.org/W2365855942","https://openalex.org/W3197408156","https://openalex.org/W2294482627","https://openalex.org/W2550931345","https://openalex.org/W2561069816","https://openalex.org/W2337755337","https://openalex.org/W4393322599","https://openalex.org/W2801997553","https://openalex.org/W4312054342"],"abstract_inverted_index":{"Fatigue":[0,25],"is":[1,17,42,81,93],"defined":[2],"as":[3,29,36],"a":[4,133],"decline":[5],"in":[6,51,88,109,165],"the":[7,45,60,97,110,117,137,151,158,166],"ability":[8],"and":[9,41,77,102,157],"efficiency":[10],"of":[11,44,49,63,99,113,119,141,150,154,161,168],"mental":[12,21,64,79,100,114,142,155,169],"and/or":[13,22],"physical":[14,23,30],"activities":[15],"that":[16,59,78],"caused":[18,83],"by":[19,85],"excessive":[20],"activities.":[24],"can":[26],"be":[27],"classified":[28],"or":[31],"mental.":[32],"Mental":[33],"fatigue":[34,65,80,156],"manifests":[35],"potentially":[37],"impaired":[38,86],"cognitive":[39,68,125,162],"function":[40],"one":[43],"most":[46],"significant":[47],"causes":[48],"accidents":[50],"modern":[52],"society.":[53],"Recently,":[54],"it":[55],"has":[56],"been":[57],"shown":[58],"neural":[61,111,152],"mechanisms":[62,112,153,160],"related":[66],"to":[67,123,147],"task":[69,126,163],"performance":[70,164],"are":[71,107],"more":[72],"complex":[73],"than":[74],"previously":[75],"thought":[76],"not":[82],"only":[84],"activity":[87,118],"task-related":[89,120],"brain":[90,121],"regions.":[91],"There":[92],"accumulating":[94],"evidence":[95],"supporting":[96],"existence":[98],"facilitation":[101],"inhibition":[103],"systems.":[104],"These":[105],"systems":[106],"involved":[108],"fatigue,":[115],"modulating":[116],"regions":[122],"regulate":[124],"performance.":[127],"In":[128],"this":[129],"review,":[130],"we":[131],"propose":[132],"new":[134],"conceptual":[135],"model:":[136],"dual":[138],"regulation":[139],"system":[140],"fatigue.":[143,170],"This":[144],"model":[145],"contributes":[146],"our":[148],"understanding":[149],"regulatory":[159],"presence":[167]},"counts_by_year":[{"year":2026,"cited_by_count":20},{"year":2025,"cited_by_count":38},{"year":2024,"cited_by_count":38},{"year":2023,"cited_by_count":25},{"year":2022,"cited_by_count":20},{"year":2021,"cited_by_count":26},{"year":2020,"cited_by_count":23},{"year":2019,"cited_by_count":17},{"year":2018,"cited_by_count":14},{"year":2017,"cited_by_count":5},{"year":2016,"cited_by_count":8},{"year":2015,"cited_by_count":2}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}