{"id":"https://openalex.org/W1969901634","doi":"https://doi.org/10.1021/ol1011967","title":"Design and Investigation of a Series of Rhodamine-Based Fluorescent Probes for Optical Measurements of pH","display_name":"Design and Investigation of a Series of Rhodamine-Based Fluorescent Probes for Optical Measurements of pH","publication_year":2010,"publication_date":"2010-06-24","ids":{"openalex":"https://openalex.org/W1969901634","doi":"https://doi.org/10.1021/ol1011967","mag":"1969901634","pmid":"https://pubmed.ncbi.nlm.nih.gov/20572677","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/2925113"},"language":"en","primary_location":{"id":"doi:10.1021/ol1011967","doi":"https://doi.org/10.1021/ol1011967","is_oa":false,"landing_page_url":"https://doi.org/10.1021/ol1011967","pdf_url":null,"source":{"id":"https://openalex.org/S201989124","display_name":"Organic Letters","issn_l":"1523-7052","issn":["1523-7052","1523-7060"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320006","host_organization_name":"American Chemical Society","host_organization_lineage":["https://openalex.org/P4310320006"],"host_organization_lineage_names":["American Chemical Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Organic Letters","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/2925113","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5090142060","display_name":"Quinn A. Best","orcid":"https://orcid.org/0000-0002-7688-5066","observed_orcids":["https://orcid.org/0000-0002-7688-5066"]},"institutions":[{"id":"https://openalex.org/I110378019","display_name":"Southern Illinois University Carbondale","ror":"https://ror.org/049kefs16","country_code":"US","type":"education","lineage":["https://openalex.org/I110378019","https://openalex.org/I2801502357"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Quinn A. Best","raw_affiliation_strings":["Department of Chemistry and Biochemistry, Southern Illinois University, Carbondale, Illinois 62901","Department of Chemistry and Biochemistry, Southern Illinois University, Carbondale, Illinois 62901, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry and Biochemistry, Southern Illinois University, Carbondale, Illinois 62901","institution_ids":["https://openalex.org/I110378019"]},{"raw_affiliation_string":"Department of Chemistry and Biochemistry, Southern Illinois University, Carbondale, Illinois 62901, USA","institution_ids":["https://openalex.org/I110378019"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5057746795","display_name":"Ruisong Xu","orcid":"https://orcid.org/0000-0003-0780-6106","observed_orcids":["https://orcid.org/0000-0003-0780-6106"]},"institutions":[{"id":"https://openalex.org/I110378019","display_name":"Southern Illinois University Carbondale","ror":"https://ror.org/049kefs16","country_code":"US","type":"education","lineage":["https://openalex.org/I110378019","https://openalex.org/I2801502357"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Ruisong Xu","raw_affiliation_strings":["Department of Chemistry and Biochemistry, Southern Illinois University, Carbondale, Illinois 62901"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry and Biochemistry, Southern Illinois University, Carbondale, Illinois 62901","institution_ids":["https://openalex.org/I110378019"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5091678543","display_name":"Matthew E. McCarroll","orcid":"https://orcid.org/0000-0003-2629-7925","observed_orcids":["https://orcid.org/0000-0003-2629-7925"]},"institutions":[{"id":"https://openalex.org/I110378019","display_name":"Southern Illinois University Carbondale","ror":"https://ror.org/049kefs16","country_code":"US","type":"education","lineage":["https://openalex.org/I110378019","https://openalex.org/I2801502357"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Matthew E. McCarroll","raw_affiliation_strings":["Department of Chemistry and Biochemistry, Southern Illinois University, Carbondale, Illinois 62901"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry and Biochemistry, Southern Illinois University, Carbondale, Illinois 62901","institution_ids":["https://openalex.org/I110378019"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5055014215","display_name":"Lichang Wang","orcid":"https://orcid.org/0000-0002-6131-3532","observed_orcids":["https://orcid.org/0000-0002-6131-3532"]},"institutions":[{"id":"https://openalex.org/I110378019","display_name":"Southern Illinois University Carbondale","ror":"https://ror.org/049kefs16","country_code":"US","type":"education","lineage":["https://openalex.org/I110378019","https://openalex.org/I2801502357"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Lichang Wang","raw_affiliation_strings":["Department of Chemistry and Biochemistry, Southern Illinois University, Carbondale, Illinois 62901"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry and Biochemistry, Southern Illinois University, Carbondale, Illinois 62901","institution_ids":["https://openalex.org/I110378019"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5114164799","display_name":"Daniel J. Dyer","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I110378019","display_name":"Southern Illinois University Carbondale","ror":"https://ror.org/049kefs16","country_code":"US","type":"education","lineage":["https://openalex.org/I110378019","https://openalex.org/I2801502357"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Daniel J. Dyer","raw_affiliation_strings":["Department of Chemistry and Biochemistry, Southern Illinois University, Carbondale, Illinois 62901"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry and Biochemistry, Southern Illinois University, Carbondale, Illinois 62901","institution_ids":["https://openalex.org/I110378019"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5114164799"],"corresponding_institution_ids":["https://openalex.org/I110378019"],"apc_list":{"value":4500,"currency":"USD","value_usd":4500},"apc_paid":null,"fwci":6.4606,"has_fulltext":false,"cited_by_count":140,"citation_normalized_percentile":{"value":0.97970145,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":93,"max":100},"biblio":{"volume":"12","issue":"14","first_page":"3219","last_page":"3221"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10532","display_name":"Molecular Sensors and Ion Detection","score":0.9932000041007996,"subfield":{"id":"https://openalex.org/subfields/1607","display_name":"Spectroscopy"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10532","display_name":"Molecular Sensors and Ion Detection","score":0.9932000041007996,"subfield":{"id":"https://openalex.org/subfields/1607","display_name":"Spectroscopy"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11472","display_name":"Analytical Chemistry and Sensors","score":0.005400000140070915,"subfield":{"id":"https://openalex.org/subfields/1502","display_name":"Bioengineering"},"field":{"id":"https://openalex.org/fields/15","display_name":"Chemical Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11240","display_name":"Luminescence and Fluorescent Materials","score":0.00039999998989515007,"subfield":{"id":"https://openalex.org/subfields/2505","display_name":"Materials Chemistry"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/rhodamine-b","display_name":"rhodamine B","score":0.871999979019165},{"id":"https://openalex.org/keywords/fluorescent-ph-indicator","display_name":"pH-sensitive fluorescent probe","score":0.8140000104904175},{"id":"https://openalex.org/keywords/fluorescence-quenching","display_name":"fluorescence quenching","score":0.7639999985694885},{"id":"https://openalex.org/keywords/electron-transfer-quenching","display_name":"electron transfer quenching","score":0.765999972820282}],"concepts":[{"id":"https://openalex.org/C2778617687","wikidata":"https://www.wikidata.org/wiki/Q2448456","display_name":"Fluorophore","level":3,"score":0.9080286026000977},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.8736289739608765},{"id":"https://openalex.org/C91881484","wikidata":"https://www.wikidata.org/wiki/Q191807","display_name":"Fluorescence","level":2,"score":0.8535489439964294},{"id":"https://openalex.org/C2779916640","wikidata":"https://www.wikidata.org/wiki/Q420410","display_name":"Rhodamine","level":3,"score":0.8485147953033447},{"id":"https://openalex.org/C2776568683","wikidata":"https://www.wikidata.org/wiki/Q23005640","display_name":"Moiety","level":2,"score":0.8122842311859131},{"id":"https://openalex.org/C131779359","wikidata":"https://www.wikidata.org/wiki/Q471875","display_name":"Amine gas treating","level":2,"score":0.6482375860214233},{"id":"https://openalex.org/C121745418","wikidata":"https://www.wikidata.org/wiki/Q585536","display_name":"Quenching (fluorescence)","level":3,"score":0.6475061178207397},{"id":"https://openalex.org/C2776002898","wikidata":"https://www.wikidata.org/wiki/Q429022","display_name":"Rhodamine B","level":4,"score":0.6096961498260498},{"id":"https://openalex.org/C143724316","wikidata":"https://www.wikidata.org/wiki/Q312468","display_name":"Series (stratigraphy)","level":2,"score":0.45451945066452026},{"id":"https://openalex.org/C32909587","wikidata":"https://www.wikidata.org/wiki/Q11369","display_name":"Molecule","level":2,"score":0.450067400932312},{"id":"https://openalex.org/C75473681","wikidata":"https://www.wikidata.org/wiki/Q188651","display_name":"Photochemistry","level":1,"score":0.42822128534317017},{"id":"https://openalex.org/C21951064","wikidata":"https://www.wikidata.org/wiki/Q899212","display_name":"Combinatorial chemistry","level":1,"score":0.37505602836608887},{"id":"https://openalex.org/C71240020","wikidata":"https://www.wikidata.org/wiki/Q186011","display_name":"Stereochemistry","level":1,"score":0.201288640499115},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.1769854724407196},{"id":"https://openalex.org/C120665830","wikidata":"https://www.wikidata.org/wiki/Q14620","display_name":"Optics","level":1,"score":0.07637423276901245},{"id":"https://openalex.org/C151730666","wikidata":"https://www.wikidata.org/wiki/Q7205","display_name":"Paleontology","level":1,"score":0.0},{"id":"https://openalex.org/C65165184","wikidata":"https://www.wikidata.org/wiki/Q218831","display_name":"Photocatalysis","level":3,"score":0.0},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.0},{"id":"https://openalex.org/C161790260","wikidata":"https://www.wikidata.org/wiki/Q82264","display_name":"Catalysis","level":2,"score":0.0},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D005456","descriptor_name":"Fluorescent Dyes","qualifier_ui":"Q000138","qualifier_name":"chemical synthesis","is_major_topic":true},{"descriptor_ui":"D005456","descriptor_name":"Fluorescent Dyes","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D006863","descriptor_name":"Hydrogen-Ion Concentration","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012235","descriptor_name":"Rhodamines","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D015195","descriptor_name":"Drug Design","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D055620","descriptor_name":"Optical Phenomena","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":3,"locations":[{"id":"doi:10.1021/ol1011967","doi":"https://doi.org/10.1021/ol1011967","is_oa":false,"landing_page_url":"https://doi.org/10.1021/ol1011967","pdf_url":null,"source":{"id":"https://openalex.org/S201989124","display_name":"Organic Letters","issn_l":"1523-7052","issn":["1523-7052","1523-7060"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320006","host_organization_name":"American Chemical Society","host_organization_lineage":["https://openalex.org/P4310320006"],"host_organization_lineage_names":["American Chemical Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Organic Letters","raw_type":"journal-article"},{"id":"pmid:20572677","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/20572677","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Organic letters","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:2925113","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/2925113","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"Org Lett","raw_type":"Text"}],"best_oa_location":{"id":"pmh:oai:pubmedcentral.nih.gov:2925113","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/2925113","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"Org Lett","raw_type":"Text"},"sustainable_development_goals":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G752688689","display_name":"Design and evaluation of response selective fluorescent sensors","funder_award_id":"R15GM080721","funder_id":"https://openalex.org/F4320337354","funder_display_name":"National Institute of General Medical Sciences"}],"funders":[{"id":"https://openalex.org/F4320337354","display_name":"National Institute of General Medical Sciences","ror":"https://ror.org/04q48ey07"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":26,"referenced_works":["https://openalex.org/W1965694893","https://openalex.org/W1981042035","https://openalex.org/W1981079665","https://openalex.org/W1986936685","https://openalex.org/W1991209913","https://openalex.org/W1994263492","https://openalex.org/W2011936508","https://openalex.org/W2017750646","https://openalex.org/W2023843739","https://openalex.org/W2023944441","https://openalex.org/W2024183228","https://openalex.org/W2037929517","https://openalex.org/W2039438672","https://openalex.org/W2047006474","https://openalex.org/W2055857036","https://openalex.org/W2063155405","https://openalex.org/W2066851948","https://openalex.org/W2070283224","https://openalex.org/W2087435364","https://openalex.org/W2088196110","https://openalex.org/W2123301821","https://openalex.org/W2130277532","https://openalex.org/W2130630814","https://openalex.org/W2145617380","https://openalex.org/W2145773666","https://openalex.org/W2165028550"],"related_works":["https://openalex.org/W2058411155","https://openalex.org/W2515545227","https://openalex.org/W2104254964","https://openalex.org/W2530561907","https://openalex.org/W2609787431","https://openalex.org/W342927119","https://openalex.org/W3201392010","https://openalex.org/W4383426598","https://openalex.org/W2128118514","https://openalex.org/W2961314685"],"abstract_inverted_index":{"A":[0],"series":[1],"of":[2,39],"structurally":[3],"similar":[4],"fluorescent":[5],"probes":[6],"(1-4),":[7],"synthesized":[8],"from":[9,29,51],"rhodamine":[10],"B,":[11],"were":[12],"designed":[13],"to":[14,31],"optically":[15],"measure":[16],"pH.":[17],"Each":[18],"probe":[19,45],"had":[20],"a":[21,36],"unique":[22],"\"off-on\"":[23],"response":[24],"as":[25],"the":[26,40,52],"solution":[27],"went":[28],"basic":[30],"acidic.":[32],"Probes":[33],"1-3":[34],"exhibited":[35],"spirocyclic":[37],"quenching":[38],"pyronin":[41],"B":[42],"fluorophore,":[43],"whereas":[44],"4":[46],"was":[47],"quenched":[48],"by":[49],"PET":[50],"amine":[53],"moiety.":[54]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":3},{"year":2023,"cited_by_count":6},{"year":2022,"cited_by_count":8},{"year":2021,"cited_by_count":7},{"year":2020,"cited_by_count":9},{"year":2019,"cited_by_count":11},{"year":2018,"cited_by_count":8},{"year":2017,"cited_by_count":9},{"year":2016,"cited_by_count":6},{"year":2015,"cited_by_count":13},{"year":2014,"cited_by_count":14},{"year":2013,"cited_by_count":22},{"year":2012,"cited_by_count":15}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}