{"id":"https://openalex.org/W1969809156","doi":"https://doi.org/10.1097/00006205-200311000-00012","title":"Herpes Simplex Virus Type 2: An Update","display_name":"Herpes Simplex Virus Type 2: An Update","publication_year":2003,"publication_date":"2003-11-01","ids":{"openalex":"https://openalex.org/W1969809156","doi":"https://doi.org/10.1097/00006205-200311000-00012","mag":"1969809156","pmid":"https://pubmed.ncbi.nlm.nih.gov/14657740"},"language":"en","primary_location":{"id":"doi:10.1097/00006205-200311000-00012","doi":"https://doi.org/10.1097/00006205-200311000-00012","is_oa":false,"landing_page_url":"https://doi.org/10.1097/00006205-200311000-00012","pdf_url":null,"source":{"id":"https://openalex.org/S4210206853","display_name":"The Nurse Practitioner","issn_l":"0361-1817","issn":["0361-1817","1538-8662"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","medline","poland-20","russia-white-list-3"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Nurse Practitioner","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5080727282","display_name":"Hayley Mark","orcid":"https://orcid.org/0009-0005-1659-264X","observed_orcids":["https://orcid.org/0009-0005-1659-264X"]},"institutions":[{"id":"https://openalex.org/I145311948","display_name":"Johns Hopkins University","ror":"https://ror.org/00za53h95","country_code":"US","type":"education","lineage":["https://openalex.org/I145311948"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Hayley D. Mark","raw_affiliation_strings":["Johns Hopkins University, School of Nursing, Baltimore, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Johns Hopkins University, School of Nursing, Baltimore, USA","institution_ids":["https://openalex.org/I145311948"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5023546972","display_name":"Ashley P. Hanahan","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I145311948","display_name":"Johns Hopkins University","ror":"https://ror.org/00za53h95","country_code":"US","type":"education","lineage":["https://openalex.org/I145311948"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Ashley P. Hanahan","raw_affiliation_strings":["ABOUT THE AUTHORS","Johns Hopkins University ("],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"ABOUT THE AUTHORS","institution_ids":[]},{"raw_affiliation_string":"Johns Hopkins University (","institution_ids":["https://openalex.org/I145311948"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5029910056","display_name":"Stacie C. Stender","orcid":"https://orcid.org/0000-0001-9719-358X","observed_orcids":["https://orcid.org/0000-0001-9719-358X"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Stacie C. Stender","raw_affiliation_strings":["ABOUT THE AUTHORS","Academic Centers"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"ABOUT THE AUTHORS","institution_ids":[]},{"raw_affiliation_string":"Academic Centers","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":1,"citation_normalized_percentile":{"value":0.11087323,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"28","issue":"11","first_page":"34","last_page":"37"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10625","display_name":"Herpesvirus Infections and Treatments","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10625","display_name":"Herpesvirus Infections and Treatments","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10981","display_name":"Cytomegalovirus and herpesvirus research","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10428","display_name":"Reproductive tract infections research","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2404","display_name":"Microbiology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/herpes-simplex-virus-type-2","display_name":"herpes simplex virus type 2","score":0.9990000128746033},{"id":"https://openalex.org/keywords/genital-herpes","display_name":"genital herpes","score":0.996999979019165},{"id":"https://openalex.org/keywords/hsv-2-transmission","display_name":"HSV-2 transmission","score":0.972000002861023},{"id":"https://openalex.org/keywords/risk-factors","display_name":"risk factors","score":0.9599999785423279},{"id":"https://openalex.org/keywords/clinical-characteristics","display_name":"clinical features","score":0.9909999966621399},{"id":"https://openalex.org/keywords/undiagnosed-infection","display_name":"undiagnosed infection","score":0.703000009059906}],"concepts":[{"id":"https://openalex.org/C107130276","wikidata":"https://www.wikidata.org/wiki/Q133805","display_name":"Epidemiology","level":2,"score":0.8342232704162598},{"id":"https://openalex.org/C2781196997","wikidata":"https://www.wikidata.org/wiki/Q655331","display_name":"Herpes simplex virus","level":3,"score":0.8298884630203247},{"id":"https://openalex.org/C761482","wikidata":"https://www.wikidata.org/wiki/Q118093","display_name":"Transmission (telecommunications)","level":2,"score":0.7077470421791077},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.5737497806549072},{"id":"https://openalex.org/C2778498788","wikidata":"https://www.wikidata.org/wiki/Q7476596","display_name":"Genital herpes","level":4,"score":0.5388924479484558},{"id":"https://openalex.org/C159047783","wikidata":"https://www.wikidata.org/wiki/Q7215","display_name":"Virology","level":1,"score":0.5267110466957092},{"id":"https://openalex.org/C2777601897","wikidata":"https://www.wikidata.org/wiki/Q3409113","display_name":"Presentation (obstetrics)","level":2,"score":0.48985859751701355},{"id":"https://openalex.org/C2909813250","wikidata":"https://www.wikidata.org/wiki/Q7476596","display_name":"Herpes Genitalis","level":5,"score":0.4441044330596924},{"id":"https://openalex.org/C2522874641","wikidata":"https://www.wikidata.org/wiki/Q808","display_name":"Virus","level":2,"score":0.39446812868118286},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.3252410888671875},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.15753132104873657},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.11661601066589355},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.07875099778175354},{"id":"https://openalex.org/C76155785","wikidata":"https://www.wikidata.org/wiki/Q418","display_name":"Telecommunications","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000914","descriptor_name":"Antibodies, Viral","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D000998","descriptor_name":"Antiviral Agents","qualifier_ui":"Q000191","qualifier_name":"economics","is_major_topic":false},{"descriptor_ui":"D000998","descriptor_name":"Antiviral Agents","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D006561","descriptor_name":"Herpes Simplex","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":true},{"descriptor_ui":"D006561","descriptor_name":"Herpes Simplex","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012307","descriptor_name":"Risk Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012698","descriptor_name":"Serologic Tests","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014481","descriptor_name":"United States","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":false},{"descriptor_ui":"D018258","descriptor_name":"Herpesvirus 2, Human","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1097/00006205-200311000-00012","doi":"https://doi.org/10.1097/00006205-200311000-00012","is_oa":false,"landing_page_url":"https://doi.org/10.1097/00006205-200311000-00012","pdf_url":null,"source":{"id":"https://openalex.org/S4210206853","display_name":"The Nurse Practitioner","issn_l":"0361-1817","issn":["0361-1817","1538-8662"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","medline","poland-20","russia-white-list-3"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Nurse Practitioner","raw_type":"journal-article"},{"id":"pmid:14657740","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/14657740","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Nurse practitioner","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.9940000176429749}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320321519","display_name":"Centre National d\u2019Etudes Spatiales","ror":"https://ror.org/04h1h0y33"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":20,"referenced_works":["https://openalex.org/W1972495334","https://openalex.org/W1979304958","https://openalex.org/W1999013810","https://openalex.org/W2009121298","https://openalex.org/W2023088041","https://openalex.org/W2040535955","https://openalex.org/W2042436673","https://openalex.org/W2065221380","https://openalex.org/W2087743885","https://openalex.org/W2102390355","https://openalex.org/W2107555337","https://openalex.org/W2133241248","https://openalex.org/W2150490377","https://openalex.org/W2155576328","https://openalex.org/W2170100593","https://openalex.org/W2310632873","https://openalex.org/W2319146475","https://openalex.org/W2334917064","https://openalex.org/W4239484513","https://openalex.org/W4246805798"],"related_works":["https://openalex.org/W2075428860","https://openalex.org/W4235776846","https://openalex.org/W2101474398","https://openalex.org/W2129796532","https://openalex.org/W2762836606","https://openalex.org/W2033312539","https://openalex.org/W2112675991","https://openalex.org/W2010796239","https://openalex.org/W2117415519","https://openalex.org/W4213232956"],"abstract_inverted_index":{"One":[0],"out":[1],"of":[2,23,34,46,51,79],"five":[3],"adults":[4],"in":[5,26],"the":[6,12,27,47,58,69],"United":[7],"States":[8],"is":[9,20],"infected":[10],"with":[11],"herpes":[13,53],"simplex":[14],"virus":[15],"type":[16],"2":[17],"(HSV-2).":[18],"This":[19,62],"an":[21],"increase":[22],"over":[24,57],"30%":[25],"past":[28],"two":[29,60],"decades.":[30,61],"1":[31],"The":[32],"majority":[33],"infections":[35],"are":[36],"undiagnosed":[37],"and":[38,42,49,77],"unrecognized":[39],"by":[40],"patients":[41],"clinicians.":[43],"Our":[44],"understanding":[45],"epidemiology":[48],"transmission":[50],"genital":[52],"has":[54],"increased":[55],"substantially":[56],"last":[59],"article":[63],"will":[64],"present":[65],"updated":[66],"information":[67],"on":[68],"epidemiology,":[70],"transmission,":[71],"risk":[72],"factors,":[73],"diagnosis,":[74],"clinical":[75],"presentation":[76],"management":[78],"HSV-2.":[80]},"counts_by_year":[],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}