{"id":"https://openalex.org/W1969534725","doi":"https://doi.org/10.1016/s0009-8981(00)00216-3","title":"Spectrophotometric assay for serum platelet-activating factor acetylhydrolase activity","display_name":"Spectrophotometric assay for serum platelet-activating factor acetylhydrolase activity","publication_year":2000,"publication_date":"2000-06-01","ids":{"openalex":"https://openalex.org/W1969534725","doi":"https://doi.org/10.1016/s0009-8981(00)00216-3","mag":"1969534725","pmid":"https://pubmed.ncbi.nlm.nih.gov/10807978"},"language":"en","primary_location":{"id":"doi:10.1016/s0009-8981(00)00216-3","doi":"https://doi.org/10.1016/s0009-8981(00)00216-3","is_oa":false,"landing_page_url":"https://doi.org/10.1016/s0009-8981(00)00216-3","pdf_url":null,"source":{"id":"https://openalex.org/S207549998","display_name":"Clinica Chimica Acta","issn_l":"0009-8981","issn":["0009-8981","1873-3492"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clinica Chimica Acta","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5047985676","display_name":"Tetsuya Kosaka","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4405264238","display_name":"Azwell Inc. (Japan)","ror":"https://ror.org/01bjtz868","country_code":"JP","type":"company","lineage":["https://openalex.org/I4405264238"]}],"countries":["JP"],"is_corresponding":true,"raw_author_name":"Tetsuya Kosaka","raw_affiliation_strings":["Diagnostic Research & Development Department, R&D Division, Nesco Company, Azwell Inc., 2-24-3 Sho, Ibaraki, Osaka, Japan. nskrd-06@mbd.sphere.ne.jp","Diagnostic Research & Development Department, R&D Division, Nesco Company, Azwell Inc., 2-24-3 Sho, Ibaraki, Osaka 567-0806, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Diagnostic Research & Development Department, R&D Division, Nesco Company, Azwell Inc., 2-24-3 Sho, Ibaraki, Osaka, Japan. nskrd-06@mbd.sphere.ne.jp","institution_ids":["https://openalex.org/I4405264238"]},{"raw_affiliation_string":"Diagnostic Research & Development Department, R&D Division, Nesco Company, Azwell Inc., 2-24-3 Sho, Ibaraki, Osaka 567-0806, Japan","institution_ids":["https://openalex.org/I4405264238"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Masahiro Yamaguchi","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4405264238","display_name":"Azwell Inc. (Japan)","ror":"https://ror.org/01bjtz868","country_code":"JP","type":"company","lineage":["https://openalex.org/I4405264238"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Masahiro Yamaguchi","raw_affiliation_strings":["Diagnostic Research & Development Department, R&D Division, Nesco Company, Azwell Inc., 2-24-3 Sho, Ibaraki, Osaka 567-0806, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Diagnostic Research & Development Department, R&D Division, Nesco Company, Azwell Inc., 2-24-3 Sho, Ibaraki, Osaka 567-0806, Japan","institution_ids":["https://openalex.org/I4405264238"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5056072408","display_name":"Yasuji Soda","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4405264238","display_name":"Azwell Inc. (Japan)","ror":"https://ror.org/01bjtz868","country_code":"JP","type":"company","lineage":["https://openalex.org/I4405264238"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Yasuji Soda","raw_affiliation_strings":["Pharmacokinetic Research Department, R & D Division, Nesco Company, Azwell Inc., 2-24-3 Sho, Ibaraki, Osaka 567-0806, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Pharmacokinetic Research Department, R & D Division, Nesco Company, Azwell Inc., 2-24-3 Sho, Ibaraki, Osaka 567-0806, Japan","institution_ids":["https://openalex.org/I4405264238"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5041123972","display_name":"Tatsuya Kishimoto","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4405264238","display_name":"Azwell Inc. (Japan)","ror":"https://ror.org/01bjtz868","country_code":"JP","type":"company","lineage":["https://openalex.org/I4405264238"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Tatsuya Kishimoto","raw_affiliation_strings":["Diagnostic Research & Development Department, R&D Division, Nesco Company, Azwell Inc., 2-24-3 Sho, Ibaraki, Osaka 567-0806, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Diagnostic Research & Development Department, R&D Division, Nesco Company, Azwell Inc., 2-24-3 Sho, Ibaraki, Osaka 567-0806, Japan","institution_ids":["https://openalex.org/I4405264238"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Akio Tago","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4405264238","display_name":"Azwell Inc. (Japan)","ror":"https://ror.org/01bjtz868","country_code":"JP","type":"company","lineage":["https://openalex.org/I4405264238"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Akio Tago","raw_affiliation_strings":["Pharmacokinetic Research Department, R & D Division, Nesco Company, Azwell Inc., 2-24-3 Sho, Ibaraki, Osaka 567-0806, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Pharmacokinetic Research Department, R & D Division, Nesco Company, Azwell Inc., 2-24-3 Sho, Ibaraki, Osaka 567-0806, Japan","institution_ids":["https://openalex.org/I4405264238"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5061635019","display_name":"Mitsuyoshi Toyosato","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4405264238","display_name":"Azwell Inc. (Japan)","ror":"https://ror.org/01bjtz868","country_code":"JP","type":"company","lineage":["https://openalex.org/I4405264238"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Mitsuyoshi Toyosato","raw_affiliation_strings":["Diagnostic Research & Development Department, R&D Division, Nesco Company, Azwell Inc., 2-24-3 Sho, Ibaraki, Osaka 567-0806, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Diagnostic Research & Development Department, R&D Division, Nesco Company, Azwell Inc., 2-24-3 Sho, Ibaraki, Osaka 567-0806, Japan","institution_ids":["https://openalex.org/I4405264238"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5103096814","display_name":"Koji Mizuno","orcid":"https://orcid.org/0000-0001-8934-0076","observed_orcids":["https://orcid.org/0000-0001-8934-0076"]},"institutions":[{"id":"https://openalex.org/I4405264238","display_name":"Azwell Inc. (Japan)","ror":"https://ror.org/01bjtz868","country_code":"JP","type":"company","lineage":["https://openalex.org/I4405264238"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Koji Mizuno","raw_affiliation_strings":["Diagnostic Research & Development Department, R&D Division, Nesco Company, Azwell Inc., 2-24-3 Sho, Ibaraki, Osaka 567-0806, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Diagnostic Research & Development Department, R&D Division, Nesco Company, Azwell Inc., 2-24-3 Sho, Ibaraki, Osaka 567-0806, Japan","institution_ids":["https://openalex.org/I4405264238"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5047985676"],"corresponding_institution_ids":["https://openalex.org/I4405264238"],"apc_list":{"value":3550,"currency":"USD","value_usd":3550},"apc_paid":null,"fwci":1.9999,"has_fulltext":false,"cited_by_count":68,"citation_normalized_percentile":{"value":0.8543883,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":98},"biblio":{"volume":"296","issue":"1-2","first_page":"151","last_page":"161"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12975","display_name":"Paraoxonase enzyme and polymorphisms","score":0.5019999742507935,"subfield":{"id":"https://openalex.org/subfields/1308","display_name":"Clinical Biochemistry"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T12975","display_name":"Paraoxonase enzyme and polymorphisms","score":0.5019999742507935,"subfield":{"id":"https://openalex.org/subfields/1308","display_name":"Clinical Biochemistry"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11308","display_name":"Sphingolipid Metabolism and Signaling","score":0.1843000054359436,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11844","display_name":"Lipid metabolism and biosynthesis","score":0.1005999967455864,"subfield":{"id":"https://openalex.org/subfields/1303","display_name":"Biochemistry"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/lipoprotein-associated-phospholipase-a2","display_name":"lipoprotein-associated phospholipase A2","score":0.996999979019165},{"id":"https://openalex.org/keywords/platelet-activating-factor","display_name":"platelet-activating factor","score":0.8450000286102295},{"id":"https://openalex.org/keywords/enzyme-activity-assay","display_name":"enzyme activity assay","score":0.6029999852180481},{"id":"https://openalex.org/keywords/automated-analyzers","display_name":"automated analyzers","score":0.5049999952316284},{"id":"https://openalex.org/keywords/clinical-diagnostics","display_name":"clinical diagnostics","score":0.6290000081062317}],"concepts":[{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.7056899070739746},{"id":"https://openalex.org/C2779020240","wikidata":"https://www.wikidata.org/wiki/Q420577","display_name":"Platelet-activating factor","level":2,"score":0.6567777991294861},{"id":"https://openalex.org/C2777289219","wikidata":"https://www.wikidata.org/wiki/Q7632154","display_name":"Substrate (aquarium)","level":2,"score":0.5878668427467346},{"id":"https://openalex.org/C2776330855","wikidata":"https://www.wikidata.org/wiki/Q650187","display_name":"Phosphatidylcholine","level":4,"score":0.56474769115448},{"id":"https://openalex.org/C89560881","wikidata":"https://www.wikidata.org/wiki/Q101026","display_name":"Platelet","level":2,"score":0.5447638034820557},{"id":"https://openalex.org/C43617362","wikidata":"https://www.wikidata.org/wiki/Q170050","display_name":"Chromatography","level":1,"score":0.5434030890464783},{"id":"https://openalex.org/C159973064","wikidata":"https://www.wikidata.org/wiki/Q3740205","display_name":"Platelet factor 4","level":3,"score":0.4412734806537628},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.36651158332824707},{"id":"https://openalex.org/C2778918659","wikidata":"https://www.wikidata.org/wiki/Q186915","display_name":"Phospholipid","level":3,"score":0.16190338134765625},{"id":"https://openalex.org/C41625074","wikidata":"https://www.wikidata.org/wiki/Q176088","display_name":"Membrane","level":2,"score":0.12780627608299255},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.1082000732421875},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.09844952821731567},{"id":"https://openalex.org/C18903297","wikidata":"https://www.wikidata.org/wiki/Q7150","display_name":"Ecology","level":1,"score":0.0},{"id":"https://openalex.org/C2777557582","wikidata":"https://www.wikidata.org/wiki/Q190016","display_name":"Heparin","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D002793","descriptor_name":"Cholic Acids","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006868","descriptor_name":"Hydrolysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009596","descriptor_name":"Nitrophenols","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010741","descriptor_name":"Phospholipases A","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D010972","descriptor_name":"Platelet Activating Factor","qualifier_ui":"Q000031","qualifier_name":"analogs & derivatives","is_major_topic":false},{"descriptor_ui":"D012680","descriptor_name":"Sensitivity and Specificity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013053","descriptor_name":"Spectrophotometry","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D013379","descriptor_name":"Substrate Specificity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D043203","descriptor_name":"1-Alkyl-2-acetylglycerophosphocholine Esterase","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1016/s0009-8981(00)00216-3","doi":"https://doi.org/10.1016/s0009-8981(00)00216-3","is_oa":false,"landing_page_url":"https://doi.org/10.1016/s0009-8981(00)00216-3","pdf_url":null,"source":{"id":"https://openalex.org/S207549998","display_name":"Clinica Chimica Acta","issn_l":"0009-8981","issn":["0009-8981","1873-3492"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clinica Chimica Acta","raw_type":"journal-article"},{"id":"pmid:10807978","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/10807978","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clinica chimica acta; international journal of clinical chemistry","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.46810001134872437,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":38,"referenced_works":["https://openalex.org/W1030813074","https://openalex.org/W1547302919","https://openalex.org/W1574747042","https://openalex.org/W1585449429","https://openalex.org/W1589395925","https://openalex.org/W1648812418","https://openalex.org/W1965669732","https://openalex.org/W1976006013","https://openalex.org/W1977898346","https://openalex.org/W2010549751","https://openalex.org/W2015250987","https://openalex.org/W2015887844","https://openalex.org/W2017396307","https://openalex.org/W2020693113","https://openalex.org/W2030140594","https://openalex.org/W2032886124","https://openalex.org/W2034454243","https://openalex.org/W2040974208","https://openalex.org/W2056160603","https://openalex.org/W2056374467","https://openalex.org/W2056736266","https://openalex.org/W2076332509","https://openalex.org/W2076993762","https://openalex.org/W2077250137","https://openalex.org/W2080486016","https://openalex.org/W2080664733","https://openalex.org/W2081186670","https://openalex.org/W2086494613","https://openalex.org/W2105100107","https://openalex.org/W2109542255","https://openalex.org/W2121121770","https://openalex.org/W2126722729","https://openalex.org/W2303547795","https://openalex.org/W2413227253","https://openalex.org/W2413589958","https://openalex.org/W2416375825","https://openalex.org/W2417370144","https://openalex.org/W2443559117"],"related_works":["https://openalex.org/W2074661020","https://openalex.org/W7217174709","https://openalex.org/W1968624712","https://openalex.org/W18937202","https://openalex.org/W2056160603","https://openalex.org/W2022277215","https://openalex.org/W1569720938","https://openalex.org/W7218174786","https://openalex.org/W2413227253","https://openalex.org/W7217276601"],"abstract_inverted_index":null,"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":1},{"year":2021,"cited_by_count":2},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":3},{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":3},{"year":2015,"cited_by_count":1},{"year":2014,"cited_by_count":3},{"year":2013,"cited_by_count":2},{"year":2012,"cited_by_count":6}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}