{"id":"https://openalex.org/W1969232123","doi":"https://doi.org/10.1055/s-2006-955639","title":"Diastereoselective Synthesis of Pyrrolidines and Prolines","display_name":"Diastereoselective Synthesis of Pyrrolidines and Prolines","publication_year":2006,"publication_date":"2006-11-23","ids":{"openalex":"https://openalex.org/W1969232123","doi":"https://doi.org/10.1055/s-2006-955639","mag":"1969232123"},"language":"en","primary_location":{"id":"doi:10.1055/s-2006-955639","doi":"https://doi.org/10.1055/s-2006-955639","is_oa":true,"landing_page_url":"https://doi.org/10.1055/s-2006-955639","pdf_url":"http://www.thieme-connect.de/products/ejournals/pdf/10.1055/s-2006-955639.pdf","source":{"id":"https://openalex.org/S135102583","display_name":"Synfacts","issn_l":"1861-194X","issn":["1861-194X","1861-1958"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core"],"host_organization":"https://openalex.org/P4310321135","host_organization_name":"Georg Thieme Verlag","host_organization_lineage":["https://openalex.org/P4310321135","https://openalex.org/P4310320000"],"host_organization_lineage_names":["Georg Thieme Verlag","Thieme Medical Publishers (Germany)"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Synfacts","raw_type":"journal-article"},"volume":null,"type":"editorial","indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"http://www.thieme-connect.de/products/ejournals/pdf/10.1055/s-2006-955639.pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5041773055","display_name":"Arun Kumar Ghosh","orcid":"https://orcid.org/0000-0003-2472-1841","observed_orcids":["https://orcid.org/0000-0003-2472-1841"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"A. Ghosh","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5003629724","display_name":"Sarang S. Kulkarni","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"S. Kulkarni","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5039408326","display_name":"Chunfa Xu","orcid":"https://orcid.org/0000-0001-7232-6956","observed_orcids":["https://orcid.org/0000-0001-7232-6956"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"C.-X. Xu","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5057330382","display_name":"Phillip Edward Fanwick","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"P. Fanwick","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":"2006","issue":"12","first_page":"1245","last_page":"1245"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10817","display_name":"Multicomponent Synthesis of Heterocycles","score":0.5454000234603882,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10817","display_name":"Multicomponent Synthesis of Heterocycles","score":0.5454000234603882,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10013","display_name":"Asymmetric Synthesis and Catalysis","score":0.26759999990463257,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T13859","display_name":"Organic Chemistry Synthesis Methods","score":0.13339999318122864,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/diastereoselective-synthesis","display_name":"diastereoselective synthesis","score":0.9679999947547913},{"id":"https://openalex.org/keywords/pyrrolidine","display_name":"pyrrolidine","score":0.9629999995231628},{"id":"https://openalex.org/keywords/proline","display_name":"proline","score":0.8659999966621399},{"id":"https://openalex.org/keywords/multicomponent-reactions","display_name":"multicomponent reactions","score":0.9810000061988831},{"id":"https://openalex.org/keywords/contiguous-stereocenters","display_name":"contiguous stereocenters","score":0.9300000071525574},{"id":"https://openalex.org/keywords/pyrrolidine-synthesis","display_name":"pyrrolidine synthesis","score":0.5619999766349792},{"id":"https://openalex.org/keywords/proline-biosynthesis","display_name":"proline biosynthesis","score":0.5289999842643738}],"concepts":[{"id":"https://openalex.org/C134195300","wikidata":"https://www.wikidata.org/wiki/Q902071","display_name":"Stereocenter","level":4,"score":0.9628685712814331},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.9013240337371826},{"id":"https://openalex.org/C108204754","wikidata":"https://www.wikidata.org/wiki/Q353392","display_name":"Adduct","level":2,"score":0.8457155227661133},{"id":"https://openalex.org/C2778851528","wikidata":"https://www.wikidata.org/wiki/Q408898","display_name":"Pyrrolidine","level":2,"score":0.8210608959197998},{"id":"https://openalex.org/C2778659115","wikidata":"https://www.wikidata.org/wiki/Q243992","display_name":"Furan","level":2,"score":0.6702769994735718},{"id":"https://openalex.org/C71240020","wikidata":"https://www.wikidata.org/wiki/Q186011","display_name":"Stereochemistry","level":1,"score":0.5628944039344788},{"id":"https://openalex.org/C118792377","wikidata":"https://www.wikidata.org/wiki/Q108584245","display_name":"Selectivity","level":3,"score":0.5192051529884338},{"id":"https://openalex.org/C2779815552","wikidata":"https://www.wikidata.org/wiki/Q484583","display_name":"Proline","level":3,"score":0.4472537636756897},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.2268669605255127},{"id":"https://openalex.org/C146686406","wikidata":"https://www.wikidata.org/wiki/Q898628","display_name":"Enantioselective synthesis","level":3,"score":0.19569072127342224},{"id":"https://openalex.org/C515207424","wikidata":"https://www.wikidata.org/wiki/Q8066","display_name":"Amino acid","level":2,"score":0.16468706727027893},{"id":"https://openalex.org/C161790260","wikidata":"https://www.wikidata.org/wiki/Q82264","display_name":"Catalysis","level":2,"score":0.11875179409980774},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.036667704582214355}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1055/s-2006-955639","doi":"https://doi.org/10.1055/s-2006-955639","is_oa":true,"landing_page_url":"https://doi.org/10.1055/s-2006-955639","pdf_url":"http://www.thieme-connect.de/products/ejournals/pdf/10.1055/s-2006-955639.pdf","source":{"id":"https://openalex.org/S135102583","display_name":"Synfacts","issn_l":"1861-194X","issn":["1861-194X","1861-1958"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core"],"host_organization":"https://openalex.org/P4310321135","host_organization_name":"Georg Thieme Verlag","host_organization_lineage":["https://openalex.org/P4310321135","https://openalex.org/P4310320000"],"host_organization_lineage_names":["Georg Thieme Verlag","Thieme Medical Publishers (Germany)"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Synfacts","raw_type":"journal-article"}],"best_oa_location":{"id":"doi:10.1055/s-2006-955639","doi":"https://doi.org/10.1055/s-2006-955639","is_oa":true,"landing_page_url":"https://doi.org/10.1055/s-2006-955639","pdf_url":"http://www.thieme-connect.de/products/ejournals/pdf/10.1055/s-2006-955639.pdf","source":{"id":"https://openalex.org/S135102583","display_name":"Synfacts","issn_l":"1861-194X","issn":["1861-194X","1861-1958"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core"],"host_organization":"https://openalex.org/P4310321135","host_organization_name":"Georg Thieme Verlag","host_organization_lineage":["https://openalex.org/P4310321135","https://openalex.org/P4310320000"],"host_organization_lineage_names":["Georg Thieme Verlag","Thieme Medical Publishers (Germany)"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Synfacts","raw_type":"journal-article"},"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W1969232123.pdf","grobid_xml":"https://content.openalex.org/works/W1969232123.grobid-xml"},"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2133246293","https://openalex.org/W2444040540","https://openalex.org/W2949484982","https://openalex.org/W2951773227","https://openalex.org/W2016319133","https://openalex.org/W2081854542","https://openalex.org/W4306398923","https://openalex.org/W2951783459","https://openalex.org/W2071741330","https://openalex.org/W2492399999"],"abstract_inverted_index":{"Significance":[0],"The":[1,15,25,63],"report":[2],"constitutes":[3],"one":[4],"of":[5,27,37,76],"the":[6,43,69,74,84],"few":[7],"multicomponent":[8],"reactions":[9],"(MCR)":[10],"that":[11],"generate":[12],"multiple":[13],"stereocenters.":[14],"method":[16,39],"created":[17],"three":[18],"contiguous":[19],"stereocenters":[20],"in":[21,73],"a":[22,38],"single":[23],"operation.":[24],"rearrangement":[26],"furan":[28],"adduct":[29,71],"5":[30,72],"to":[31],"pyrrolidine":[32],"4":[33,91],"is":[34],"an":[35,79],"extension":[36],"developed":[40],"previously":[41],"by":[42],"same":[44],"group":[45],"(A.":[46],"K.":[47],"Ghosh,":[48],"C.-X.":[49],"Xu,":[50],"S.":[51,52],"Kulkarni,":[53],"D.":[54],"Wink":[55],"Org.":[56],"Lett.":[57],"2005":[58],",":[59,61],"7":[60,93],"7-10).":[62],"reaction":[64],"can":[65],"be":[66],"halted":[67],"at":[68],"THF":[70],"presence":[75],"MeCN":[77],"as":[78],"additive.":[80],"In":[81],"all":[82],"cases,":[83],"MCR":[85],"yielded":[86],"highly":[87],"substituted":[88],"proline":[89],"derivatives":[90],"and":[92],"with":[94],"excellent":[95],"diastereo\u00adselectivity.":[96]},"counts_by_year":[],"updated_date":"2026-09-22T06:50:58.402377","created_date":"2016-06-24T00:00:00"}