{"id":"https://openalex.org/W196906534","doi":"https://doi.org/10.1021/bk-2009-1016.ch007","title":"Portable Analytical Systems for On-Site Diagnosis of Exposure to Pesticides and Nerve Agents","display_name":"Portable Analytical Systems for On-Site Diagnosis of Exposure to Pesticides and Nerve Agents","publication_year":2009,"publication_date":"2009-12-11","ids":{"openalex":"https://openalex.org/W196906534","doi":"https://doi.org/10.1021/bk-2009-1016.ch007","mag":"196906534"},"language":"en","primary_location":{"id":"doi:10.1021/bk-2009-1016.ch007","doi":"https://doi.org/10.1021/bk-2009-1016.ch007","is_oa":false,"landing_page_url":"https://doi.org/10.1021/bk-2009-1016.ch007","pdf_url":null,"source":{"id":"https://openalex.org/S205053445","display_name":"ACS symposium series","issn_l":"0097-6156","issn":["0097-6156","1947-5918"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","jufo-1","norway-1"],"host_organization":"https://openalex.org/P4310320006","host_organization_name":"American Chemical Society","host_organization_lineage":["https://openalex.org/P4310320006"],"host_organization_lineage_names":["American Chemical Society"],"type":"book series"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"ACS Symposium Series","raw_type":"book-chapter"},"volume":{"id":"https://openalex.org/W568834316","display_name":"Nanoscience and Nanotechnology for Chemical and Biological Defense"},"type":"conference-paper","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5012861155","display_name":"Yuehe Lin","orcid":"https://orcid.org/0000-0003-3791-7587","observed_orcids":["https://orcid.org/0000-0003-3791-7587"]},"institutions":[{"id":"https://openalex.org/I142606810","display_name":"Pacific Northwest National Laboratory","ror":"https://ror.org/05h992307","country_code":"US","type":"facility","lineage":["https://openalex.org/I1325736334","https://openalex.org/I1330989302","https://openalex.org/I142606810","https://openalex.org/I39565521"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Yuehe Lin","raw_affiliation_strings":["Pacific Northwest National Laboratory, Richland, WA 99352"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Pacific Northwest National Laboratory, Richland, WA 99352","institution_ids":["https://openalex.org/I142606810"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112205818","display_name":"Jun Wang","orcid":"https://orcid.org/0000-0002-7187-0893","observed_orcids":["https://orcid.org/0000-0002-7187-0893"]},"institutions":[{"id":"https://openalex.org/I142606810","display_name":"Pacific Northwest National Laboratory","ror":"https://ror.org/05h992307","country_code":"US","type":"facility","lineage":["https://openalex.org/I1325736334","https://openalex.org/I1330989302","https://openalex.org/I142606810","https://openalex.org/I39565521"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jun Wang","raw_affiliation_strings":["Pacific Northwest National Laboratory, Richland, WA 99352"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Pacific Northwest National Laboratory, Richland, WA 99352","institution_ids":["https://openalex.org/I142606810"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108787609","display_name":"Guodong Liu","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I142606810","display_name":"Pacific Northwest National Laboratory","ror":"https://ror.org/05h992307","country_code":"US","type":"facility","lineage":["https://openalex.org/I1325736334","https://openalex.org/I1330989302","https://openalex.org/I142606810","https://openalex.org/I39565521"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Guodong Liu","raw_affiliation_strings":["Pacific Northwest National Laboratory, Richland, WA 99352"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Pacific Northwest National Laboratory, Richland, WA 99352","institution_ids":["https://openalex.org/I142606810"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5047337288","display_name":"Charles A. Timchalk","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I142606810","display_name":"Pacific Northwest National Laboratory","ror":"https://ror.org/05h992307","country_code":"US","type":"facility","lineage":["https://openalex.org/I1325736334","https://openalex.org/I1330989302","https://openalex.org/I142606810","https://openalex.org/I39565521"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Charles Timchalk","raw_affiliation_strings":["Pacific Northwest National Laboratory, Richland, WA 99352"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Pacific Northwest National Laboratory, Richland, WA 99352","institution_ids":["https://openalex.org/I142606810"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I142606810"],"apc_list":null,"apc_paid":null,"fwci":0.4788,"has_fulltext":false,"cited_by_count":4,"citation_normalized_percentile":{"value":0.50685852,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":94},"biblio":{"volume":null,"issue":null,"first_page":"85","last_page":"98"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10212","display_name":"Electrochemical sensors and biosensors","score":0.9175000190734863,"subfield":{"id":"https://openalex.org/subfields/2208","display_name":"Electrical and Electronic Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10212","display_name":"Electrochemical sensors and biosensors","score":0.9175000190734863,"subfield":{"id":"https://openalex.org/subfields/2208","display_name":"Electrical and Electronic Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11393","display_name":"Biosensors and Analytical Detection","score":0.02019999921321869,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10875","display_name":"Pesticide Exposure and Toxicity","score":0.016300000250339508,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/organophosphate-pesticides","display_name":"organophosphorus pesticides","score":0.9670000076293945},{"id":"https://openalex.org/keywords/portable-analytical-system","display_name":"portable analytical system","score":0.9210000038146973},{"id":"https://openalex.org/keywords/functionalized-carbon-nanotubes","display_name":"functionalized carbon nanotubes","score":0.8820000290870667},{"id":"https://openalex.org/keywords/zirconia-nanoparticles","display_name":"zirconia nanoparticles","score":0.9990000128746033},{"id":"https://openalex.org/keywords/quantum-dots","display_name":"quantum dots","score":1.0},{"id":"https://openalex.org/keywords/electrochemical-sensor","display_name":"electrochemical sensor","score":0.7549999952316284},{"id":"https://openalex.org/keywords/immunoassay","display_name":"immunoassay","score":0.9350000023841858},{"id":"https://openalex.org/keywords/biomonitoring","display_name":"biomonitoring","score":0.7540000081062317},{"id":"https://openalex.org/keywords/organophosphate-metabolites","display_name":"organophosphate metabolites","score":0.8809999823570251}],"concepts":[{"id":"https://openalex.org/C138631740","wikidata":"https://www.wikidata.org/wiki/Q967847","display_name":"Nanomaterials","level":2,"score":0.6916329860687256},{"id":"https://openalex.org/C171250308","wikidata":"https://www.wikidata.org/wiki/Q11468","display_name":"Nanotechnology","level":1,"score":0.6063092947006226},{"id":"https://openalex.org/C2778706303","wikidata":"https://www.wikidata.org/wiki/Q2612896","display_name":"Nerve agent","level":4,"score":0.5984281301498413},{"id":"https://openalex.org/C513720949","wikidata":"https://www.wikidata.org/wiki/Q1778729","display_name":"Carbon nanotube","level":2,"score":0.4963589310646057},{"id":"https://openalex.org/C161176658","wikidata":"https://www.wikidata.org/wiki/Q131656","display_name":"Pesticide","level":2,"score":0.4586593508720398},{"id":"https://openalex.org/C109051061","wikidata":"https://www.wikidata.org/wiki/Q864610","display_name":"Biomonitoring","level":2,"score":0.44295555353164673},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.3428229093551636},{"id":"https://openalex.org/C107872376","wikidata":"https://www.wikidata.org/wiki/Q321355","display_name":"Environmental chemistry","level":1,"score":0.3020908236503601},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.2964578866958618},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.06294804811477661},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.06150171160697937},{"id":"https://openalex.org/C2778816929","wikidata":"https://www.wikidata.org/wiki/Q22676679","display_name":"Acetylcholinesterase","level":3,"score":0.0},{"id":"https://openalex.org/C6557445","wikidata":"https://www.wikidata.org/wiki/Q173113","display_name":"Agronomy","level":1,"score":0.0},{"id":"https://openalex.org/C181199279","wikidata":"https://www.wikidata.org/wiki/Q8047","display_name":"Enzyme","level":2,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1021/bk-2009-1016.ch007","doi":"https://doi.org/10.1021/bk-2009-1016.ch007","is_oa":false,"landing_page_url":"https://doi.org/10.1021/bk-2009-1016.ch007","pdf_url":null,"source":{"id":"https://openalex.org/S205053445","display_name":"ACS symposium series","issn_l":"0097-6156","issn":["0097-6156","1947-5918"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","jufo-1","norway-1"],"host_organization":"https://openalex.org/P4310320006","host_organization_name":"American Chemical Society","host_organization_lineage":["https://openalex.org/P4310320006"],"host_organization_lineage_names":["American Chemical Society"],"type":"book series"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"ACS Symposium Series","raw_type":"book-chapter"}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320306084","display_name":"U.S. Department of Energy","ror":"https://ror.org/01bj3aw27"},{"id":"https://openalex.org/F4320306250","display_name":"Battelle","ror":"https://ror.org/01h5tnr73"},{"id":"https://openalex.org/F4320332162","display_name":"Centers for Disease Control and Prevention","ror":"https://ror.org/042twtr12"},{"id":"https://openalex.org/F4320337359","display_name":"National Institute of Neurological Disorders and Stroke","ror":"https://ror.org/01s5ya894"},{"id":"https://openalex.org/F4320337382","display_name":"National Institute for Occupational Safety and Health","ror":"https://ror.org/0502a2655"},{"id":"https://openalex.org/F4320337509","display_name":"Biological and Environmental Research","ror":"https://ror.org/0114b2m14"},{"id":"https://openalex.org/F4320338354","display_name":"Pacific Northwest National Laboratory","ror":"https://ror.org/05h992307"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2582155394","https://openalex.org/W2022065375","https://openalex.org/W3200663053","https://openalex.org/W4409784424","https://openalex.org/W4412637760","https://openalex.org/W7221673800","https://openalex.org/W2028888876","https://openalex.org/W4408962072","https://openalex.org/W4417357668","https://openalex.org/W4402683285"],"abstract_inverted_index":{"In":[0],"this":[1],"chapter,":[2],"we":[3],"summarize":[4],"recent":[5],"work":[6],"in":[7,20,78],"our":[8,90],"laboratory":[9],"on":[10,37],"the":[11,69,98,107,110,121],"development":[12],"of":[13,23,73,86,109,128],"sensitive":[14],"portable":[15,100],"analytical":[16,101],"systems":[17,34,102],"for":[18,84,106,120],"use":[19],"on-site":[21,124],"detection":[22,108,125],"exposure":[24,88],"to":[25],"organophosphate":[26],"(OP)":[27],"pesticides":[28],"and":[29,47,62,75,123,126],"chemical":[30],"nerve":[31],"agents.":[32],"These":[33],"are":[35],"based":[36],"various":[38,48],"nanomaterials":[39,53],"functioning":[40],"as":[41],"transducers;":[42],"recognition":[43],"agents":[44],"or":[45],"labels":[46],"elelectrochemical/immunoassay":[49],"techniques.":[50],"The":[51],"studied":[52],"included":[54],"functionalized":[55],"carbon":[56],"nanotubes":[57],"(CNT),":[58],"zirconia":[59],"nanoparticles":[60],"(NPs)":[61],"quantum":[63],"dots":[64],"(QDs).":[65],"Three":[66],"biomarkers":[67],"e.g.":[68],"free":[70],"OPs,":[71],"metabolites":[72],"OPs":[74],"protein-OP":[76],"adducts":[77],"biological":[79],"matrices":[80],"have":[81,103],"been":[82,95],"employed":[83],"biomonitoring":[85],"OP":[87,129],"with":[89],"developed":[91],"system.":[92],"It":[93],"has":[94],"found":[96],"that":[97,114],"nanomaterial-based":[99],"high":[104],"sensitivity":[105],"biomarkers,":[111],"which":[112],"suggest":[113],"these":[115],"technologies":[116],"offer":[117],"great":[118],"promise":[119],"rapid":[122],"evaluation":[127],"exposure.":[130]},"counts_by_year":[{"year":2024,"cited_by_count":1},{"year":2014,"cited_by_count":1},{"year":2013,"cited_by_count":1},{"year":2012,"cited_by_count":1}],"updated_date":"2026-10-10T09:11:00.788812","created_date":"2016-06-24T00:00:00"}