{"id":"https://openalex.org/W1968884377","doi":"https://doi.org/10.1074/jbc.273.44.28633","title":"Laminin-1 and Laminin-2 G-domain Synthetic Peptides Bind Syndecan-1 and Are Involved in Acinar Formation of a Human Submandibular Gland Cell Line","display_name":"Laminin-1 and Laminin-2 G-domain Synthetic Peptides Bind Syndecan-1 and Are Involved in Acinar Formation of a Human Submandibular Gland Cell Line","publication_year":1998,"publication_date":"1998-11-01","ids":{"openalex":"https://openalex.org/W1968884377","doi":"https://doi.org/10.1074/jbc.273.44.28633","mag":"1968884377","pmid":"https://pubmed.ncbi.nlm.nih.gov/9786856"},"language":"en","primary_location":{"id":"doi:10.1074/jbc.273.44.28633","doi":"https://doi.org/10.1074/jbc.273.44.28633","is_oa":true,"landing_page_url":"https://doi.org/10.1074/jbc.273.44.28633","pdf_url":"https://www.sciencedirect.com/science/article/pii/S0021925819594364/pdf","source":{"id":"https://openalex.org/S140251998","display_name":"Journal of Biological Chemistry","issn_l":"0021-9258","issn":["0021-9258","1067-8816","1083-351X"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-100","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Biological Chemistry","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://www.sciencedirect.com/science/article/pii/S0021925819594364/pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5020349785","display_name":"Matthew P. Hoffman","orcid":"https://orcid.org/0000-0002-8293-5998","observed_orcids":["https://orcid.org/0000-0002-8293-5998","https://orcid.org/0000-0003-4295-4665"]},"institutions":[{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Matthew P. Hoffman","raw_affiliation_strings":["Craniofacial Developmental Biology and Regeneration Branch, NIDR, National Institutes of Health, Bethesda, Maryland 20892-4370, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Craniofacial Developmental Biology and Regeneration Branch, NIDR, National Institutes of Health, Bethesda, Maryland 20892-4370, USA","institution_ids":["https://openalex.org/I1299303238"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5090371447","display_name":"Motoyoshi Nomizu","orcid":"https://orcid.org/0000-0002-2264-2907","observed_orcids":["https://orcid.org/0000-0002-2264-2907"]},"institutions":[{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Motoyoshi Nomizu","raw_affiliation_strings":["Craniofacial Developmental Biology and Regeneration Branch, NIDR, National Institutes of Health, Bethesda, Maryland 20892-4370"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Craniofacial Developmental Biology and Regeneration Branch, NIDR, National Institutes of Health, Bethesda, Maryland 20892-4370","institution_ids":["https://openalex.org/I1299303238"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5066490660","display_name":"Eva Roque","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Eva Roque","raw_affiliation_strings":["Craniofacial Developmental Biology and Regeneration Branch, NIDR, National Institutes of Health, Bethesda, Maryland 20892-4370"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Craniofacial Developmental Biology and Regeneration Branch, NIDR, National Institutes of Health, Bethesda, Maryland 20892-4370","institution_ids":["https://openalex.org/I1299303238"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5067218028","display_name":"Sharon Chih Lin Lee","orcid":"https://orcid.org/0000-0001-8995-9784","observed_orcids":["https://orcid.org/0000-0001-8995-9784"]},"institutions":[{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Sharon Lee","raw_affiliation_strings":["Craniofacial Developmental Biology and Regeneration Branch, NIDR, National Institutes of Health, Bethesda, Maryland 20892-4370"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Craniofacial Developmental Biology and Regeneration Branch, NIDR, National Institutes of Health, Bethesda, Maryland 20892-4370","institution_ids":["https://openalex.org/I1299303238"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5024429482","display_name":"Dale W. Jung","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Dale W. Jung","raw_affiliation_strings":["Craniofacial Developmental Biology and Regeneration Branch, NIDR, National Institutes of Health, Bethesda, Maryland 20892-4370"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Craniofacial Developmental Biology and Regeneration Branch, NIDR, National Institutes of Health, Bethesda, Maryland 20892-4370","institution_ids":["https://openalex.org/I1299303238"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112762251","display_name":"Yoshi Yamada","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Yoshi Yamada","raw_affiliation_strings":["Craniofacial Developmental Biology and Regeneration Branch, NIDR, National Institutes of Health, Bethesda, Maryland 20892-4370"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Craniofacial Developmental Biology and Regeneration Branch, NIDR, National Institutes of Health, Bethesda, Maryland 20892-4370","institution_ids":["https://openalex.org/I1299303238"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5054622398","display_name":"Hynda K. Kleinman","orcid":"https://orcid.org/0000-0002-8220-9769","observed_orcids":["https://orcid.org/0000-0002-8220-9769"]},"institutions":[{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Hynda K. Kleinman","raw_affiliation_strings":["Craniofacial Developmental Biology and Regeneration Branch, NIDR, National Institutes of Health, Bethesda, Maryland 20892-4370"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Craniofacial Developmental Biology and Regeneration Branch, NIDR, National Institutes of Health, Bethesda, Maryland 20892-4370","institution_ids":["https://openalex.org/I1299303238"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5054622398"],"corresponding_institution_ids":["https://openalex.org/I1299303238"],"apc_list":{"value":3430,"currency":"USD","value_usd":3430},"apc_paid":{"value":3430,"currency":"USD","value_usd":3430},"fwci":3.8086,"has_fulltext":true,"cited_by_count":186,"citation_normalized_percentile":{"value":0.93405699,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":99},"biblio":{"volume":"273","issue":"44","first_page":"28633","last_page":"28641"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10831","display_name":"Cell Adhesion Molecules Research","score":0.8125,"subfield":{"id":"https://openalex.org/subfields/2723","display_name":"Immunology and Allergy"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10831","display_name":"Cell Adhesion Molecules Research","score":0.8125,"subfield":{"id":"https://openalex.org/subfields/2723","display_name":"Immunology and Allergy"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11521","display_name":"Salivary Gland Disorders and Functions","score":0.07209999859333038,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11131","display_name":"Proteoglycans and glycosaminoglycans research","score":0.024700000882148743,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/laminin-1","display_name":"laminin-1","score":0.9769999980926514},{"id":"https://openalex.org/keywords/laminin-2","display_name":"laminin-2","score":0.9990000128746033},{"id":"https://openalex.org/keywords/g-domain","display_name":"G-domain","score":0.5849999785423279},{"id":"https://openalex.org/keywords/synthetic-peptides","display_name":"synthetic peptides","score":0.8230000138282776},{"id":"https://openalex.org/keywords/syndecan-1","display_name":"syndecan-1","score":0.9850000143051147},{"id":"https://openalex.org/keywords/acinar-cell-differentiation","display_name":"acinar differentiation","score":0.9520000219345093},{"id":"https://openalex.org/keywords/submandibular-gland-cells","display_name":"submandibular gland cells","score":0.8980000019073486},{"id":"https://openalex.org/keywords/beta1-integrin","display_name":"beta1 integrin","score":0.9319999814033508},{"id":"https://openalex.org/keywords/heparan-sulfate","display_name":"heparan sulfate","score":0.7720000147819519},{"id":"https://openalex.org/keywords/heparitinase","display_name":"heparitinase","score":0.8289999961853027},{"id":"https://openalex.org/keywords/cell-adhesion","display_name":"cell adhesion","score":0.9380000233650208},{"id":"https://openalex.org/keywords/cell-surface-ligands","display_name":"cell surface ligands","score":0.6589999794960022},{"id":"https://openalex.org/keywords/lumen-formation","display_name":"lumen formation","score":0.6019999980926514},{"id":"https://openalex.org/keywords/integrin-binding-site","display_name":"integrin binding site","score":0.421999990940094}],"concepts":[{"id":"https://openalex.org/C2779814568","wikidata":"https://www.wikidata.org/wiki/Q58345","display_name":"Laminin","level":3,"score":0.9246221780776978},{"id":"https://openalex.org/C195687474","wikidata":"https://www.wikidata.org/wiki/Q409715","display_name":"Integrin","level":3,"score":0.5897583365440369},{"id":"https://openalex.org/C85789140","wikidata":"https://www.wikidata.org/wiki/Q187640","display_name":"Cell adhesion","level":3,"score":0.5077770352363586},{"id":"https://openalex.org/C153911025","wikidata":"https://www.wikidata.org/wiki/Q7202","display_name":"Molecular biology","level":1,"score":0.4501684308052063},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.4286021590232849},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.42719507217407227},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.42029309272766113},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.386785626411438},{"id":"https://openalex.org/C189165786","wikidata":"https://www.wikidata.org/wiki/Q193825","display_name":"Extracellular matrix","level":2,"score":0.29548341035842896},{"id":"https://openalex.org/C1491633281","wikidata":"https://www.wikidata.org/wiki/Q7868","display_name":"Cell","level":2,"score":0.2876046597957611}],"mesh":[{"descriptor_ui":"D000595","descriptor_name":"Amino Acid Sequence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002448","descriptor_name":"Cell Adhesion","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002460","descriptor_name":"Cell Line","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002462","descriptor_name":"Cell Membrane","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D002846","descriptor_name":"Chromatography, Affinity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007536","descriptor_name":"Isomerism","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007797","descriptor_name":"Laminin","qualifier_ui":"Q000302","qualifier_name":"isolation & purification","is_major_topic":false},{"descriptor_ui":"D007797","descriptor_name":"Laminin","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D007797","descriptor_name":"Laminin","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D008562","descriptor_name":"Membrane Glycoproteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D008969","descriptor_name":"Molecular Sequence Data","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010446","descriptor_name":"Peptide Fragments","qualifier_ui":"Q000302","qualifier_name":"isolation & purification","is_major_topic":false},{"descriptor_ui":"D010446","descriptor_name":"Peptide Fragments","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D011133","descriptor_name":"Polysaccharide-Lyases","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D011485","descriptor_name":"Protein Binding","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011509","descriptor_name":"Proteoglycans","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D013363","descriptor_name":"Submandibular Gland","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":false},{"descriptor_ui":"D013363","descriptor_name":"Submandibular Gland","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D015153","descriptor_name":"Blotting, Western","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019012","descriptor_name":"Integrin beta1","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D053667","descriptor_name":"Syndecans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D053668","descriptor_name":"Syndecan-1","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1074/jbc.273.44.28633","doi":"https://doi.org/10.1074/jbc.273.44.28633","is_oa":true,"landing_page_url":"https://doi.org/10.1074/jbc.273.44.28633","pdf_url":"https://www.sciencedirect.com/science/article/pii/S0021925819594364/pdf","source":{"id":"https://openalex.org/S140251998","display_name":"Journal of Biological Chemistry","issn_l":"0021-9258","issn":["0021-9258","1067-8816","1083-351X"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-100","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Biological Chemistry","raw_type":"journal-article"},{"id":"pmid:9786856","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/9786856","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of biological chemistry","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.1074/jbc.273.44.28633","doi":"https://doi.org/10.1074/jbc.273.44.28633","is_oa":true,"landing_page_url":"https://doi.org/10.1074/jbc.273.44.28633","pdf_url":"https://www.sciencedirect.com/science/article/pii/S0021925819594364/pdf","source":{"id":"https://openalex.org/S140251998","display_name":"Journal of Biological Chemistry","issn_l":"0021-9258","issn":["0021-9258","1067-8816","1083-351X"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-100","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Biological Chemistry","raw_type":"journal-article"},"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320306101","display_name":"National Aeronautics and Space Administration","ror":"https://ror.org/027ka1x80"},{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W1968884377.pdf","grobid_xml":"https://content.openalex.org/works/W1968884377.grobid-xml"},"referenced_works_count":36,"referenced_works":["https://openalex.org/W1569253487","https://openalex.org/W1569767833","https://openalex.org/W1579619270","https://openalex.org/W1964574308","https://openalex.org/W1966034730","https://openalex.org/W1978628059","https://openalex.org/W1981140691","https://openalex.org/W1989381620","https://openalex.org/W1989768887","https://openalex.org/W1992338919","https://openalex.org/W1994334713","https://openalex.org/W2007991972","https://openalex.org/W2015648732","https://openalex.org/W2016840017","https://openalex.org/W2020645947","https://openalex.org/W2037604567","https://openalex.org/W2048321002","https://openalex.org/W2058044755","https://openalex.org/W2060856005","https://openalex.org/W2069200668","https://openalex.org/W2069466168","https://openalex.org/W2071937853","https://openalex.org/W2075105055","https://openalex.org/W2081628019","https://openalex.org/W2084664594","https://openalex.org/W2093514870","https://openalex.org/W2103047766","https://openalex.org/W2113266466","https://openalex.org/W2125922025","https://openalex.org/W2143987989","https://openalex.org/W2145539666","https://openalex.org/W2163614009","https://openalex.org/W2257257862","https://openalex.org/W2406452718","https://openalex.org/W4251787522","https://openalex.org/W4255086771"],"related_works":["https://openalex.org/W2021553554","https://openalex.org/W120268546","https://openalex.org/W2041127584","https://openalex.org/W2067999123","https://openalex.org/W631647127","https://openalex.org/W2406452718","https://openalex.org/W1974598255","https://openalex.org/W1996648954","https://openalex.org/W7099864959","https://openalex.org/W2081628019"],"abstract_inverted_index":{"The":[0,38,97],"culture":[1],"of":[2,31,47,99,126,221],"human":[3],"submandibular":[4],"gland":[5],"(HSG)":[6],"cells":[7,233],"on":[8,17,50,90],"laminin-1":[9,100,127,184,222],"induces":[10],"acinar":[11,21,112,236],"differentiation.":[12,96],"We":[13,173],"identified":[14,204],"a":[15,201,213],"site":[16,216],"laminin":[18,33,91,134,230],"involved":[19],"in":[20,217],"differentiation":[22],"using":[23,178],"synthetic":[24],"peptides":[25,118,135],"derived":[26],"from":[27],"the":[28,32,45,58,71,78,117,141,161,188,192,218],"C-terminal":[29],"G-domain":[30,98],"alpha1":[34,39],"and":[35,81,104,108,119,144,152,171,183,197,223,231,241],"alpha2":[36,60],"chains.":[37],"chain":[40,61],"peptide":[41,62,180],"AG73":[42,56,151,170],"(RKRLQVQLSIRT)":[43],"decreases":[44],"size":[46],"acini":[48],"formed":[49],"laminin-1.":[51],"Cells":[52],"cultured":[53],"with":[54,164,195],"either":[55],"or":[57,136],"homologous":[59],"MG73":[63,153],"(KNRLTIELEVRT)":[64],"form":[65],"structures":[66],"that":[67,87],"appear":[68],"acinar-like,":[69],"but":[70,154],"cell":[72,148,162,175],"nuclei":[73],"are":[74,92],"not":[75,139],"polarized":[76],"to":[77,116,120,150,168,191,235],"basal":[79],"surface":[80,163,176],"no":[82,158],"lumen":[83],"formation":[84],"occurs,":[85],"indicating":[86],"additional":[88],"sites":[89],"required":[93],"for":[94,200],"complete":[95],"contains":[101],"both":[102,169,179,239],"integrin":[103],"heparin":[105],"binding":[106,215],"sites,":[107],"anti-beta1-integrin":[109,155],"antibodies":[110,156],"disrupt":[111],"formation.":[113],"Cell":[114],"adhesion":[115,149,167],"E3,":[121],"an":[122],"elastase":[123],"digest":[124],"fragment":[125],"containing":[128],"AG73,":[129],"is":[130],"specific,":[131],"since":[132],"other":[133],"EDTA":[137],"do":[138],"compete":[140],"binding.":[142],"Heparin":[143],"heparan":[145],"sulfate":[146],"decrease":[147],"have":[157],"effect.":[159],"Treating":[160,187],"heparitinase":[165,196],"inhibits":[166],"MG73.":[172],"isolated":[174],"ligands":[177],"affinity":[181,185,193],"chromatography":[182],"chromatography.":[186],"material":[189],"bound":[190],"columns":[194],"chondroitinase":[198],"enriches":[199],"core":[202],"protein":[203],"as":[205],"syndecan-1":[206,214],"by":[207],"Western":[208],"blot":[209],"analysis,":[210],"thus":[211],"identifying":[212],"globular":[219],"domain":[220],"laminin-2.":[224],"In":[225],"summary,":[226],"multiple":[227],"interactions":[228],"between":[229],"HSG":[232],"contribute":[234],"differentiation,":[237],"involving":[238],"beta1-integrins":[240],"syndecan-1.":[242]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":2},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":5},{"year":2021,"cited_by_count":5},{"year":2020,"cited_by_count":3},{"year":2019,"cited_by_count":4},{"year":2018,"cited_by_count":1},{"year":2017,"cited_by_count":4},{"year":2016,"cited_by_count":3},{"year":2015,"cited_by_count":6},{"year":2014,"cited_by_count":2},{"year":2013,"cited_by_count":4},{"year":2012,"cited_by_count":12}],"updated_date":"2026-11-05T12:25:35.769452","created_date":"2016-06-24T00:00:00"}