{"id":"https://openalex.org/W1968775513","doi":"https://doi.org/10.1097/01.pas.0000213318.66800.94","title":"Multiple Gastrointestinal Stromal Tumors: Clinicopathologic and Genetic Analysis of 12 Patients","display_name":"Multiple Gastrointestinal Stromal Tumors: Clinicopathologic and Genetic Analysis of 12 Patients","publication_year":2007,"publication_date":"2007-01-22","ids":{"openalex":"https://openalex.org/W1968775513","doi":"https://doi.org/10.1097/01.pas.0000213318.66800.94","mag":"1968775513","pmid":"https://pubmed.ncbi.nlm.nih.gov/17255767"},"language":"en","primary_location":{"id":"doi:10.1097/01.pas.0000213318.66800.94","doi":"https://doi.org/10.1097/01.pas.0000213318.66800.94","is_oa":false,"landing_page_url":"https://doi.org/10.1097/01.pas.0000213318.66800.94","pdf_url":null,"source":{"id":"https://openalex.org/S37879208","display_name":"The American Journal of Surgical Pathology","issn_l":"0147-5185","issn":["0147-5185","1532-0979"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-200","russia-white-list-1"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The American Journal of Surgical Pathology","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5023457870","display_name":"Dae Young Kang","orcid":"https://orcid.org/0000-0003-2124-4189","observed_orcids":["https://orcid.org/0000-0003-2124-4189"]},"institutions":[{"id":"https://openalex.org/I196345858","display_name":"Chungnam National University","ror":"https://ror.org/0227as991","country_code":"KR","type":"education","lineage":["https://openalex.org/I196345858"]}],"countries":["KR"],"is_corresponding":true,"raw_author_name":"Dae Young Kang","raw_affiliation_strings":["Department of Pathology, Chungnam National University, Korea","Department of Pathology, Chungnam National University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology, Chungnam National University, Korea","institution_ids":["https://openalex.org/I196345858"]},{"raw_affiliation_string":"Department of Pathology, Chungnam National University","institution_ids":["https://openalex.org/I196345858"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109262578","display_name":"Cheol Keun Park","orcid":"https://orcid.org/0000-0001-7689-0386","observed_orcids":["https://orcid.org/0000-0001-7689-0386","https://orcid.org/0000-0001-7101-5793"]},"institutions":[{"id":"https://openalex.org/I2802194831","display_name":"Samsung Medical Center","ror":"https://ror.org/05a15z872","country_code":"KR","type":"healthcare","lineage":["https://openalex.org/I2250650973","https://openalex.org/I2802194831"]},{"id":"https://openalex.org/I848706","display_name":"Sungkyunkwan University","ror":"https://ror.org/04q78tk20","country_code":"KR","type":"education","lineage":["https://openalex.org/I848706"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Cheol Keun Park","raw_affiliation_strings":["Department of Pathology, Samsung Medical Center, Sungkyunkwan University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology, Samsung Medical Center, Sungkyunkwan University","institution_ids":["https://openalex.org/I2802194831","https://openalex.org/I848706"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113746896","display_name":"Jong Sang Choi","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I197347611","display_name":"Korea University","ror":"https://ror.org/047dqcg40","country_code":"KR","type":"education","lineage":["https://openalex.org/I197347611"]},{"id":"https://openalex.org/I4210161052","display_name":"Korea University","ror":"https://ror.org/05m1gnk07","country_code":"JP","type":"education","lineage":["https://openalex.org/I4210161052"]}],"countries":["JP","KR"],"is_corresponding":false,"raw_author_name":"Jong Sang Choi","raw_affiliation_strings":["Department of Pathology, Korea University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology, Korea University","institution_ids":["https://openalex.org/I197347611","https://openalex.org/I4210161052"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112264416","display_name":"So Young Jin","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I24541011","display_name":"Soonchunhyang University","ror":"https://ror.org/03qjsrb10","country_code":"KR","type":"education","lineage":["https://openalex.org/I24541011"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"So Young Jin","raw_affiliation_strings":["Department of Pathology, Soonchunhyang University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology, Soonchunhyang University","institution_ids":["https://openalex.org/I24541011"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100436418","display_name":"Hyun Jung Kim","orcid":"https://orcid.org/0000-0002-9520-1109","observed_orcids":["https://orcid.org/0000-0002-9520-1109"]},"institutions":[{"id":"https://openalex.org/I104338594","display_name":"Inje University","ror":"https://ror.org/04xqwq985","country_code":"KR","type":"education","lineage":["https://openalex.org/I104338594"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Hyun Jung Kim","raw_affiliation_strings":["Department of Pathology, Inje University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology, Inje University","institution_ids":["https://openalex.org/I104338594"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5066378420","display_name":"Mee Joo","orcid":"https://orcid.org/0000-0002-5886-0287","observed_orcids":["https://orcid.org/0000-0002-5886-0287"]},"institutions":[{"id":"https://openalex.org/I104338594","display_name":"Inje University","ror":"https://ror.org/04xqwq985","country_code":"KR","type":"education","lineage":["https://openalex.org/I104338594"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Mee Joo","raw_affiliation_strings":["Department of Pathology, Inje University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology, Inje University","institution_ids":["https://openalex.org/I104338594"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5008023825","display_name":"Mi Seon Kang","orcid":"https://orcid.org/0000-0001-9332-8096","observed_orcids":["https://orcid.org/0000-0001-9332-8096"]},"institutions":[{"id":"https://openalex.org/I104338594","display_name":"Inje University","ror":"https://ror.org/04xqwq985","country_code":"KR","type":"education","lineage":["https://openalex.org/I104338594"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Mi Seon Kang","raw_affiliation_strings":["Department of Pathology, Inje University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology, Inje University","institution_ids":["https://openalex.org/I104338594"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5072357420","display_name":"Woo Sung Moon","orcid":"https://orcid.org/0000-0001-7951-9865","observed_orcids":["https://orcid.org/0000-0001-7951-9865"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Woo Sung Moon","raw_affiliation_strings":["Department of Pathology, Chunbuk National University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology, Chunbuk National University","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5039983284","display_name":"Ki Jung Yun","orcid":"https://orcid.org/0000-0001-9830-0797","observed_orcids":["https://orcid.org/0000-0001-9830-0797"]},"institutions":[{"id":"https://openalex.org/I77079311","display_name":"Wonkwang University","ror":"https://ror.org/006776986","country_code":"KR","type":"education","lineage":["https://openalex.org/I77079311"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Ki Jung Yun","raw_affiliation_strings":["Department of Pathology, Wonkwang University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology, Wonkwang University","institution_ids":["https://openalex.org/I77079311"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110063069","display_name":"Eun Sil Yu","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I196345858","display_name":"Chungnam National University","ror":"https://ror.org/0227as991","country_code":"KR","type":"education","lineage":["https://openalex.org/I196345858"]}],"countries":["KR"],"is_corresponding":true,"raw_author_name":"Eun Sil Yu","raw_affiliation_strings":["Department of Pathology, Chungnam National University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology, Chungnam National University","institution_ids":["https://openalex.org/I196345858"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5078456588","display_name":"Haeyun Kang","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2802194831","display_name":"Samsung Medical Center","ror":"https://ror.org/05a15z872","country_code":"KR","type":"healthcare","lineage":["https://openalex.org/I2250650973","https://openalex.org/I2802194831"]},{"id":"https://openalex.org/I848706","display_name":"Sungkyunkwan University","ror":"https://ror.org/04q78tk20","country_code":"KR","type":"education","lineage":["https://openalex.org/I848706"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Haeyun Kang","raw_affiliation_strings":["Department of Pathology, Samsung Medical Center, Sungkyunkwan University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology, Samsung Medical Center, Sungkyunkwan University","institution_ids":["https://openalex.org/I2802194831","https://openalex.org/I848706"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5055431215","display_name":"Kyoung\u2010Mee Kim","orcid":"https://orcid.org/0000-0002-1162-9205","observed_orcids":["https://orcid.org/0000-0002-1162-9205"]},"institutions":[{"id":"https://openalex.org/I2802194831","display_name":"Samsung Medical Center","ror":"https://ror.org/05a15z872","country_code":"KR","type":"healthcare","lineage":["https://openalex.org/I2250650973","https://openalex.org/I2802194831"]},{"id":"https://openalex.org/I848706","display_name":"Sungkyunkwan University","ror":"https://ror.org/04q78tk20","country_code":"KR","type":"education","lineage":["https://openalex.org/I848706"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Kyoung-Mee Kim","raw_affiliation_strings":["Department of Pathology, Samsung Medical Center, Sungkyunkwan University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology, Samsung Medical Center, Sungkyunkwan University","institution_ids":["https://openalex.org/I2802194831","https://openalex.org/I848706"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":8,"corresponding_author_ids":["https://openalex.org/A5023457870","https://openalex.org/A5110063069"],"corresponding_institution_ids":["https://openalex.org/I196345858"],"apc_list":null,"apc_paid":null,"fwci":8.9528,"has_fulltext":false,"cited_by_count":108,"citation_normalized_percentile":{"value":0.98150221,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":99},"biblio":{"volume":"31","issue":"2","first_page":"224","last_page":"232"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11485","display_name":"Gastrointestinal Tumor Research and Treatment","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2715","display_name":"Gastroenterology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11485","display_name":"Gastrointestinal Tumor Research and Treatment","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2715","display_name":"Gastroenterology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11173","display_name":"Neurofibromatosis and Schwannoma Cases","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Clinical Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11991","display_name":"Soft tissue tumor case studies","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/kit-mutations","display_name":"KIT mutations","score":0.7139999866485596},{"id":"https://openalex.org/keywords/pdgfra-mutation","display_name":"PDGFRA mutation","score":0.953000009059906},{"id":"https://openalex.org/keywords/neurofibromatosis-type-1","display_name":"neurofibromatosis type 1","score":0.9850000143051147},{"id":"https://openalex.org/keywords/interstitial-cells-of-cajal","display_name":"interstitial cells of Cajal","score":0.8040000200271606},{"id":"https://openalex.org/keywords/jejunum","display_name":"jejunum","score":0.6610000133514404},{"id":"https://openalex.org/keywords/tumor-recurrence","display_name":"tumor recurrence","score":0.718999981880188},{"id":"https://openalex.org/keywords/prognosis","display_name":"prognosis","score":0.675000011920929}],"concepts":[{"id":"https://openalex.org/C37307934","wikidata":"https://www.wikidata.org/wiki/Q18030422","display_name":"PDGFRA","level":4,"score":0.817057192325592},{"id":"https://openalex.org/C2778984943","wikidata":"https://www.wikidata.org/wiki/Q847605","display_name":"Neurofibromatosis","level":2,"score":0.7714968323707581},{"id":"https://openalex.org/C2775922572","wikidata":"https://www.wikidata.org/wiki/Q83567","display_name":"GiST","level":3,"score":0.7184303998947144},{"id":"https://openalex.org/C201539569","wikidata":"https://www.wikidata.org/wiki/Q2596185","display_name":"Interstitial cell of Cajal","level":3,"score":0.5562620759010315},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.5289352536201477},{"id":"https://openalex.org/C2780512811","wikidata":"https://www.wikidata.org/wiki/Q11829360","display_name":"Gastrointestinal tract","level":2,"score":0.5123342275619507},{"id":"https://openalex.org/C36823959","wikidata":"https://www.wikidata.org/wiki/Q373027","display_name":"Exon","level":3,"score":0.4997422695159912},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.47521692514419556},{"id":"https://openalex.org/C13514818","wikidata":"https://www.wikidata.org/wiki/Q5552256","display_name":"Germline mutation","level":4,"score":0.466608464717865},{"id":"https://openalex.org/C2994225774","wikidata":"https://www.wikidata.org/wiki/Q42918","display_name":"Gene mutation","level":4,"score":0.4343905448913574},{"id":"https://openalex.org/C2777007597","wikidata":"https://www.wikidata.org/wiki/Q16869243","display_name":"Stromal tumor","level":3,"score":0.4331439435482025},{"id":"https://openalex.org/C501734568","wikidata":"https://www.wikidata.org/wiki/Q42918","display_name":"Mutation","level":3,"score":0.42122697830200195},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.3867614269256592},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.32030534744262695},{"id":"https://openalex.org/C16930146","wikidata":"https://www.wikidata.org/wiki/Q4381253","display_name":"Stromal cell","level":2,"score":0.30970510840415955},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.24713736772537231},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.22721704840660095},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.21020165085792542},{"id":"https://openalex.org/C204232928","wikidata":"https://www.wikidata.org/wiki/Q899285","display_name":"Immunohistochemistry","level":2,"score":0.1287248730659485}],"mesh":[{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004273","descriptor_name":"DNA, Neoplasm","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007150","descriptor_name":"Immunohistochemistry","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007413","descriptor_name":"Intestinal Mucosa","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D007413","descriptor_name":"Intestinal Mucosa","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009154","descriptor_name":"Mutation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009378","descriptor_name":"Neoplasms, Multiple Primary","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D009378","descriptor_name":"Neoplasms, Multiple Primary","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D009378","descriptor_name":"Neoplasms, Multiple Primary","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D009456","descriptor_name":"Neurofibromatosis 1","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D009456","descriptor_name":"Neurofibromatosis 1","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D012189","descriptor_name":"Retrospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018095","descriptor_name":"Germ-Line Mutation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019009","descriptor_name":"Proto-Oncogene Proteins c-kit","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D019009","descriptor_name":"Proto-Oncogene Proteins c-kit","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D020796","descriptor_name":"Receptor, Platelet-Derived Growth Factor alpha","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D020796","descriptor_name":"Receptor, Platelet-Derived Growth Factor alpha","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D046152","descriptor_name":"Gastrointestinal Stromal Tumors","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D046152","descriptor_name":"Gastrointestinal Stromal Tumors","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D046152","descriptor_name":"Gastrointestinal Stromal Tumors","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1097/01.pas.0000213318.66800.94","doi":"https://doi.org/10.1097/01.pas.0000213318.66800.94","is_oa":false,"landing_page_url":"https://doi.org/10.1097/01.pas.0000213318.66800.94","pdf_url":null,"source":{"id":"https://openalex.org/S37879208","display_name":"The American Journal of Surgical Pathology","issn_l":"0147-5185","issn":["0147-5185","1532-0979"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-200","russia-white-list-1"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The American Journal of Surgical Pathology","raw_type":"journal-article"},{"id":"pmid:17255767","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/17255767","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The American journal of surgical pathology","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.98580002784729}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":32,"referenced_works":["https://openalex.org/W1549034776","https://openalex.org/W1970041112","https://openalex.org/W1971212668","https://openalex.org/W1972600888","https://openalex.org/W1975240950","https://openalex.org/W1977422646","https://openalex.org/W1978095082","https://openalex.org/W1981491302","https://openalex.org/W1992085819","https://openalex.org/W1994834086","https://openalex.org/W2006556639","https://openalex.org/W2007328596","https://openalex.org/W2014300063","https://openalex.org/W2016654284","https://openalex.org/W2016899343","https://openalex.org/W2025518732","https://openalex.org/W2028750359","https://openalex.org/W2035157342","https://openalex.org/W2043967493","https://openalex.org/W2045515200","https://openalex.org/W2053138413","https://openalex.org/W2057470956","https://openalex.org/W2062232901","https://openalex.org/W2091678344","https://openalex.org/W2103322585","https://openalex.org/W2105396280","https://openalex.org/W2107590922","https://openalex.org/W2122573984","https://openalex.org/W2130755604","https://openalex.org/W2137211135","https://openalex.org/W2155186551","https://openalex.org/W2396593596"],"related_works":["https://openalex.org/W2382345381","https://openalex.org/W4404257307","https://openalex.org/W2282665136","https://openalex.org/W2016654284","https://openalex.org/W2098180009","https://openalex.org/W7098384339","https://openalex.org/W2248990184","https://openalex.org/W1988027300","https://openalex.org/W6983582671","https://openalex.org/W2166485548"],"abstract_inverted_index":{"Multiple":[0,165,223],"gastrointestinal":[1,155,204],"stromal":[2],"tumors":[3],"(GISTs)":[4],"are":[5,233],"extremely":[6],"rare":[7,213],"and":[8,15,29,42,63,66,74,100,112,177,229],"usually":[9],"associated":[10,103,167],"with":[11,85,94,104,157,168],"type":[12,105,169],"1":[13,106,110,135,170],"neurofibromatosis":[14,171],"familial":[16,93,113,146],"GIST.":[17],"The":[18],"aim":[19],"of":[20,32,48,71,77,97,118,140,153,160,163,181,187,200,215,220,247,252],"this":[21],"study":[22],"was":[23,58],"to":[24,35,210],"investigate":[25],"the":[26,61,123,154,175,236,241,248],"clinical,":[27,227],"phenotypic,":[28,228],"genetic":[30],"characteristics":[31,231],"multiple":[33,49,86,114,147,216],"GISTs":[34,50,115,166,201,218,224],"gain":[36],"insights":[37],"into":[38],"their":[39],"underlying":[40,238],"pathogenesis":[41],"clinical":[43],"behavior.":[44],"Forty-seven":[45],"paraffin":[46],"blocks":[47],"from":[51,60],"12":[52,83],"patients":[53,84],"were":[54,80,89,92,102,143,172],"analyzed.":[55],"Genomic":[56],"DNA":[57],"extracted":[59],"tumor":[62],"normal":[64],"mucosa":[65],"mutations":[67,96,117,142,180],"for":[68],"4":[69],"exons":[70,76],"KIT":[72,98,119,141,182,188],"gene":[73,79,120,189],"3":[75],"PDGFRA":[78],"determined.":[81],"Among":[82],"GISTs,":[87],"5":[88,101],"sporadic,":[90],"2":[91],"germline":[95],"gene,":[99],"neurofibromatosis.":[107],"All":[108],"but":[109,240],"sporadic":[111,136],"showed":[116,150],"shared":[121],"by":[122],"same":[124],"mutation":[125,190],"on":[126,235],"each":[127],"GIST":[128,148],"mass":[129],"within":[130,202],"a":[131,196,203,208,212],"patient.":[132],"But":[133],"in":[134,174,192],"case,":[137],"different":[138],"types":[139,186],"observed.":[144],"Two":[145],"cases":[149],"diffuse":[151,158],"involvement":[152],"tract":[156,205],"hyperplasia":[159],"interstitial":[161],"cell":[162],"Cajal.":[164],"located":[173],"jejunum":[176],"harbored":[178],"no":[179],"or":[183,250],"PDGFRA.":[184],"Different":[185],"found":[191],"our":[193],"case":[194],"raise":[195],"possibility":[197],"that":[198,232],"recurrence":[199],"may":[206],"have":[207],"chance":[209],"be":[211],"occurrence":[214],"primary":[217],"instead":[219],"true":[221],"recurrence.":[222],"show":[225],"unique":[226],"genotypic":[230],"dependent":[234],"particular":[237],"mechanisms,":[239],"overall":[242],"prognosis":[243],"is":[244],"favorable":[245],"regardless":[246],"numbers":[249],"phenotype":[251],"GISTs.":[253]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":3},{"year":2022,"cited_by_count":2},{"year":2021,"cited_by_count":3},{"year":2020,"cited_by_count":5},{"year":2019,"cited_by_count":4},{"year":2018,"cited_by_count":3},{"year":2017,"cited_by_count":4},{"year":2016,"cited_by_count":5},{"year":2015,"cited_by_count":8},{"year":2014,"cited_by_count":5},{"year":2013,"cited_by_count":5},{"year":2012,"cited_by_count":12}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2016-06-24T00:00:00"}