{"id":"https://openalex.org/W1968707152","doi":"https://doi.org/10.1182/blood.v97.3.708","title":"Characterization of novel natural killer (NK)\u2013cell and \u03b3\u03b4 T-cell lines established from primary lesions of nasal T/NK-cell lymphomas associated with the Epstein-Barr virus","display_name":"Characterization of novel natural killer (NK)\u2013cell and \u03b3\u03b4 T-cell lines established from primary lesions of nasal T/NK-cell lymphomas associated with the Epstein-Barr virus","publication_year":2001,"publication_date":"2001-02-01","ids":{"openalex":"https://openalex.org/W1968707152","doi":"https://doi.org/10.1182/blood.v97.3.708","mag":"1968707152","pmid":"https://pubmed.ncbi.nlm.nih.gov/11157488"},"language":"en","primary_location":{"id":"doi:10.1182/blood.v97.3.708","doi":"https://doi.org/10.1182/blood.v97.3.708","is_oa":false,"landing_page_url":"https://doi.org/10.1182/blood.v97.3.708","pdf_url":null,"source":{"id":"https://openalex.org/S200071133","display_name":"Blood","issn_l":"0006-4971","issn":["0006-4971","1528-0020"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Blood","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5075684248","display_name":"Hiroshi Nagata","orcid":"https://orcid.org/0000-0003-0902-9208","observed_orcids":["https://orcid.org/0000-0003-0902-9208"]},"institutions":[{"id":"https://openalex.org/I125602781","display_name":"Tokyo Medical and Dental University","ror":"https://ror.org/051k3eh31","country_code":"JP","type":"education","lineage":["https://openalex.org/I125602781","https://openalex.org/I4400009020"]},{"id":"https://openalex.org/I159385669","display_name":"Chiba University","ror":"https://ror.org/01hjzeq58","country_code":"JP","type":"education","lineage":["https://openalex.org/I159385669"]},{"id":"https://openalex.org/I31784960","display_name":"Fukuoka University","ror":"https://ror.org/04nt8b154","country_code":"JP","type":"education","lineage":["https://openalex.org/I31784960"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Hiroshi Nagata","raw_affiliation_strings":["From the Department of Otorhinolaryngology, School of Medicine, Chiba University, Chiba; First Department of Internal Medicine, School of Medicine, Fukuoka University, Fukuoka; and Department of Virology, Division of Virology and Immunology, Medical Research Institute, Tokyo Medical and Dental University, Tokyo, Japan","Department of Otorhinolaryngology, School of Medicine, Chiba University, Chiba","First Department of Internal Medicine, School of Medicine, Fukuoka University, Fukuoka"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Department of Otorhinolaryngology, School of Medicine, Chiba University, Chiba; First Department of Internal Medicine, School of Medicine, Fukuoka University, Fukuoka; and Department of Virology, Division of Virology and Immunology, Medical Research Institute, Tokyo Medical and Dental University, Tokyo, Japan","institution_ids":["https://openalex.org/I125602781","https://openalex.org/I159385669","https://openalex.org/I31784960"]},{"raw_affiliation_string":"Department of Otorhinolaryngology, School of Medicine, Chiba University, Chiba","institution_ids":["https://openalex.org/I159385669"]},{"raw_affiliation_string":"First Department of Internal Medicine, School of Medicine, Fukuoka University, Fukuoka","institution_ids":["https://openalex.org/I31784960"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111529101","display_name":"Akiyoshi Konno","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I125602781","display_name":"Tokyo Medical and Dental University","ror":"https://ror.org/051k3eh31","country_code":"JP","type":"education","lineage":["https://openalex.org/I125602781","https://openalex.org/I4400009020"]},{"id":"https://openalex.org/I159385669","display_name":"Chiba University","ror":"https://ror.org/01hjzeq58","country_code":"JP","type":"education","lineage":["https://openalex.org/I159385669"]},{"id":"https://openalex.org/I31784960","display_name":"Fukuoka University","ror":"https://ror.org/04nt8b154","country_code":"JP","type":"education","lineage":["https://openalex.org/I31784960"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Akiyoshi Konno","raw_affiliation_strings":["From the Department of Otorhinolaryngology, School of Medicine, Chiba University, Chiba; First Department of Internal Medicine, School of Medicine, Fukuoka University, Fukuoka; and Department of Virology, Division of Virology and Immunology, Medical Research Institute, Tokyo Medical and Dental University, Tokyo, Japan","Department of Otorhinolaryngology, School of Medicine, Chiba University, Chiba","First Department of Internal Medicine, School of Medicine, Fukuoka University, Fukuoka"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Department of Otorhinolaryngology, School of Medicine, Chiba University, Chiba; First Department of Internal Medicine, School of Medicine, Fukuoka University, Fukuoka; and Department of Virology, Division of Virology and Immunology, Medical Research Institute, Tokyo Medical and Dental University, Tokyo, Japan","institution_ids":["https://openalex.org/I125602781","https://openalex.org/I159385669","https://openalex.org/I31784960"]},{"raw_affiliation_string":"Department of Otorhinolaryngology, School of Medicine, Chiba University, Chiba","institution_ids":["https://openalex.org/I159385669"]},{"raw_affiliation_string":"First Department of Internal Medicine, School of Medicine, Fukuoka University, Fukuoka","institution_ids":["https://openalex.org/I31784960"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5105367448","display_name":"Nobuhiro Kimura","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I125602781","display_name":"Tokyo Medical and Dental University","ror":"https://ror.org/051k3eh31","country_code":"JP","type":"education","lineage":["https://openalex.org/I125602781","https://openalex.org/I4400009020"]},{"id":"https://openalex.org/I159385669","display_name":"Chiba University","ror":"https://ror.org/01hjzeq58","country_code":"JP","type":"education","lineage":["https://openalex.org/I159385669"]},{"id":"https://openalex.org/I31784960","display_name":"Fukuoka University","ror":"https://ror.org/04nt8b154","country_code":"JP","type":"education","lineage":["https://openalex.org/I31784960"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Nobuhiro Kimura","raw_affiliation_strings":["From the Department of Otorhinolaryngology, School of Medicine, Chiba University, Chiba; First Department of Internal Medicine, School of Medicine, Fukuoka University, Fukuoka; and Department of Virology, Division of Virology and Immunology, Medical Research Institute, Tokyo Medical and Dental University, Tokyo, Japan","Department of Otorhinolaryngology, School of Medicine, Chiba University, Chiba","First Department of Internal Medicine, School of Medicine, Fukuoka University, Fukuoka"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Department of Otorhinolaryngology, School of Medicine, Chiba University, Chiba; First Department of Internal Medicine, School of Medicine, Fukuoka University, Fukuoka; and Department of Virology, Division of Virology and Immunology, Medical Research Institute, Tokyo Medical and Dental University, Tokyo, Japan","institution_ids":["https://openalex.org/I125602781","https://openalex.org/I159385669","https://openalex.org/I31784960"]},{"raw_affiliation_string":"Department of Otorhinolaryngology, School of Medicine, Chiba University, Chiba","institution_ids":["https://openalex.org/I159385669"]},{"raw_affiliation_string":"First Department of Internal Medicine, School of Medicine, Fukuoka University, Fukuoka","institution_ids":["https://openalex.org/I31784960"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100433668","display_name":"Yu Zhang","orcid":"https://orcid.org/0000-0003-0220-8203","observed_orcids":["https://orcid.org/0000-0003-0220-8203"]},"institutions":[{"id":"https://openalex.org/I125602781","display_name":"Tokyo Medical and Dental University","ror":"https://ror.org/051k3eh31","country_code":"JP","type":"education","lineage":["https://openalex.org/I125602781","https://openalex.org/I4400009020"]},{"id":"https://openalex.org/I159385669","display_name":"Chiba University","ror":"https://ror.org/01hjzeq58","country_code":"JP","type":"education","lineage":["https://openalex.org/I159385669"]},{"id":"https://openalex.org/I31784960","display_name":"Fukuoka University","ror":"https://ror.org/04nt8b154","country_code":"JP","type":"education","lineage":["https://openalex.org/I31784960"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Yu Zhang","raw_affiliation_strings":["From the Department of Otorhinolaryngology, School of Medicine, Chiba University, Chiba; First Department of Internal Medicine, School of Medicine, Fukuoka University, Fukuoka; and Department of Virology, Division of Virology and Immunology, Medical Research Institute, Tokyo Medical and Dental University, Tokyo, Japan","Department of Otorhinolaryngology, School of Medicine, Chiba University, Chiba","First Department of Internal Medicine, School of Medicine, Fukuoka University, Fukuoka"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Department of Otorhinolaryngology, School of Medicine, Chiba University, Chiba; First Department of Internal Medicine, School of Medicine, Fukuoka University, Fukuoka; and Department of Virology, Division of Virology and Immunology, Medical Research Institute, Tokyo Medical and Dental University, Tokyo, Japan","institution_ids":["https://openalex.org/I125602781","https://openalex.org/I159385669","https://openalex.org/I31784960"]},{"raw_affiliation_string":"Department of Otorhinolaryngology, School of Medicine, Chiba University, Chiba","institution_ids":["https://openalex.org/I159385669"]},{"raw_affiliation_string":"First Department of Internal Medicine, School of Medicine, Fukuoka University, Fukuoka","institution_ids":["https://openalex.org/I31784960"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111605728","display_name":"Michiko Kimura","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I125602781","display_name":"Tokyo Medical and Dental University","ror":"https://ror.org/051k3eh31","country_code":"JP","type":"education","lineage":["https://openalex.org/I125602781","https://openalex.org/I4400009020"]},{"id":"https://openalex.org/I159385669","display_name":"Chiba University","ror":"https://ror.org/01hjzeq58","country_code":"JP","type":"education","lineage":["https://openalex.org/I159385669"]},{"id":"https://openalex.org/I31784960","display_name":"Fukuoka University","ror":"https://ror.org/04nt8b154","country_code":"JP","type":"education","lineage":["https://openalex.org/I31784960"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Michiko Kimura","raw_affiliation_strings":["From the Department of Otorhinolaryngology, School of Medicine, Chiba University, Chiba; First Department of Internal Medicine, School of Medicine, Fukuoka University, Fukuoka; and Department of Virology, Division of Virology and Immunology, Medical Research Institute, Tokyo Medical and Dental University, Tokyo, Japan","Department of Otorhinolaryngology, School of Medicine, Chiba University, Chiba","First Department of Internal Medicine, School of Medicine, Fukuoka University, Fukuoka"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Department of Otorhinolaryngology, School of Medicine, Chiba University, Chiba; First Department of Internal Medicine, School of Medicine, Fukuoka University, Fukuoka; and Department of Virology, Division of Virology and Immunology, Medical Research Institute, Tokyo Medical and Dental University, Tokyo, Japan","institution_ids":["https://openalex.org/I125602781","https://openalex.org/I159385669","https://openalex.org/I31784960"]},{"raw_affiliation_string":"Department of Otorhinolaryngology, School of Medicine, Chiba University, Chiba","institution_ids":["https://openalex.org/I159385669"]},{"raw_affiliation_string":"First Department of Internal Medicine, School of Medicine, Fukuoka University, Fukuoka","institution_ids":["https://openalex.org/I31784960"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5014803541","display_name":"Ayako Demachi","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I125602781","display_name":"Tokyo Medical and Dental University","ror":"https://ror.org/051k3eh31","country_code":"JP","type":"education","lineage":["https://openalex.org/I125602781","https://openalex.org/I4400009020"]},{"id":"https://openalex.org/I159385669","display_name":"Chiba University","ror":"https://ror.org/01hjzeq58","country_code":"JP","type":"education","lineage":["https://openalex.org/I159385669"]},{"id":"https://openalex.org/I31784960","display_name":"Fukuoka University","ror":"https://ror.org/04nt8b154","country_code":"JP","type":"education","lineage":["https://openalex.org/I31784960"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Ayako Demachi","raw_affiliation_strings":["From the Department of Otorhinolaryngology, School of Medicine, Chiba University, Chiba; First Department of Internal Medicine, School of Medicine, Fukuoka University, Fukuoka; and Department of Virology, Division of Virology and Immunology, Medical Research Institute, Tokyo Medical and Dental University, Tokyo, Japan","Department of Otorhinolaryngology, School of Medicine, Chiba University, Chiba","First Department of Internal Medicine, School of Medicine, Fukuoka University, Fukuoka"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Department of Otorhinolaryngology, School of Medicine, Chiba University, Chiba; First Department of Internal Medicine, School of Medicine, Fukuoka University, Fukuoka; and Department of Virology, Division of Virology and Immunology, Medical Research Institute, Tokyo Medical and Dental University, Tokyo, Japan","institution_ids":["https://openalex.org/I125602781","https://openalex.org/I159385669","https://openalex.org/I31784960"]},{"raw_affiliation_string":"Department of Otorhinolaryngology, School of Medicine, Chiba University, Chiba","institution_ids":["https://openalex.org/I159385669"]},{"raw_affiliation_string":"First Department of Internal Medicine, School of Medicine, Fukuoka University, Fukuoka","institution_ids":["https://openalex.org/I31784960"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5023423182","display_name":"Teruaki Sekine","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I125602781","display_name":"Tokyo Medical and Dental University","ror":"https://ror.org/051k3eh31","country_code":"JP","type":"education","lineage":["https://openalex.org/I125602781","https://openalex.org/I4400009020"]},{"id":"https://openalex.org/I159385669","display_name":"Chiba University","ror":"https://ror.org/01hjzeq58","country_code":"JP","type":"education","lineage":["https://openalex.org/I159385669"]},{"id":"https://openalex.org/I31784960","display_name":"Fukuoka University","ror":"https://ror.org/04nt8b154","country_code":"JP","type":"education","lineage":["https://openalex.org/I31784960"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Teruaki Sekine","raw_affiliation_strings":["From the Department of Otorhinolaryngology, School of Medicine, Chiba University, Chiba; First Department of Internal Medicine, School of Medicine, Fukuoka University, Fukuoka; and Department of Virology, Division of Virology and Immunology, Medical Research Institute, Tokyo Medical and Dental University, Tokyo, Japan","Department of Otorhinolaryngology, School of Medicine, Chiba University, Chiba","First Department of Internal Medicine, School of Medicine, Fukuoka University, Fukuoka"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Department of Otorhinolaryngology, School of Medicine, Chiba University, Chiba; First Department of Internal Medicine, School of Medicine, Fukuoka University, Fukuoka; and Department of Virology, Division of Virology and Immunology, Medical Research Institute, Tokyo Medical and Dental University, Tokyo, Japan","institution_ids":["https://openalex.org/I125602781","https://openalex.org/I159385669","https://openalex.org/I31784960"]},{"raw_affiliation_string":"Department of Otorhinolaryngology, School of Medicine, Chiba University, Chiba","institution_ids":["https://openalex.org/I159385669"]},{"raw_affiliation_string":"First Department of Internal Medicine, School of Medicine, Fukuoka University, Fukuoka","institution_ids":["https://openalex.org/I31784960"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108594433","display_name":"Kohtaro Yamamoto","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I125602781","display_name":"Tokyo Medical and Dental University","ror":"https://ror.org/051k3eh31","country_code":"JP","type":"education","lineage":["https://openalex.org/I125602781","https://openalex.org/I4400009020"]},{"id":"https://openalex.org/I159385669","display_name":"Chiba University","ror":"https://ror.org/01hjzeq58","country_code":"JP","type":"education","lineage":["https://openalex.org/I159385669"]},{"id":"https://openalex.org/I31784960","display_name":"Fukuoka University","ror":"https://ror.org/04nt8b154","country_code":"JP","type":"education","lineage":["https://openalex.org/I31784960"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Kohtaro Yamamoto","raw_affiliation_strings":["From the Department of Otorhinolaryngology, School of Medicine, Chiba University, Chiba; First Department of Internal Medicine, School of Medicine, Fukuoka University, Fukuoka; and Department of Virology, Division of Virology and Immunology, Medical Research Institute, Tokyo Medical and Dental University, Tokyo, Japan","Department of Otorhinolaryngology, School of Medicine, Chiba University, Chiba","First Department of Internal Medicine, School of Medicine, Fukuoka University, Fukuoka"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Department of Otorhinolaryngology, School of Medicine, Chiba University, Chiba; First Department of Internal Medicine, School of Medicine, Fukuoka University, Fukuoka; and Department of Virology, Division of Virology and Immunology, Medical Research Institute, Tokyo Medical and Dental University, Tokyo, Japan","institution_ids":["https://openalex.org/I125602781","https://openalex.org/I159385669","https://openalex.org/I31784960"]},{"raw_affiliation_string":"Department of Otorhinolaryngology, School of Medicine, Chiba University, Chiba","institution_ids":["https://openalex.org/I159385669"]},{"raw_affiliation_string":"First Department of Internal Medicine, School of Medicine, Fukuoka University, Fukuoka","institution_ids":["https://openalex.org/I31784960"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5046537981","display_name":"Norio Shimizu","orcid":"https://orcid.org/0000-0002-6225-233X","observed_orcids":["https://orcid.org/0000-0002-6225-233X"]},"institutions":[{"id":"https://openalex.org/I125602781","display_name":"Tokyo Medical and Dental University","ror":"https://ror.org/051k3eh31","country_code":"JP","type":"education","lineage":["https://openalex.org/I125602781","https://openalex.org/I4400009020"]},{"id":"https://openalex.org/I159385669","display_name":"Chiba University","ror":"https://ror.org/01hjzeq58","country_code":"JP","type":"education","lineage":["https://openalex.org/I159385669"]},{"id":"https://openalex.org/I31784960","display_name":"Fukuoka University","ror":"https://ror.org/04nt8b154","country_code":"JP","type":"education","lineage":["https://openalex.org/I31784960"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Norio Shimizu","raw_affiliation_strings":["From the Department of Otorhinolaryngology, School of Medicine, Chiba University, Chiba; First Department of Internal Medicine, School of Medicine, Fukuoka University, Fukuoka; and Department of Virology, Division of Virology and Immunology, Medical Research Institute, Tokyo Medical and Dental University, Tokyo, Japan","Department of Otorhinolaryngology, School of Medicine, Chiba University, Chiba","First Department of Internal Medicine, School of Medicine, Fukuoka University, Fukuoka"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Department of Otorhinolaryngology, School of Medicine, Chiba University, Chiba; First Department of Internal Medicine, School of Medicine, Fukuoka University, Fukuoka; and Department of Virology, Division of Virology and Immunology, Medical Research Institute, Tokyo Medical and Dental University, Tokyo, Japan","institution_ids":["https://openalex.org/I125602781","https://openalex.org/I159385669","https://openalex.org/I31784960"]},{"raw_affiliation_string":"Department of Otorhinolaryngology, School of Medicine, Chiba University, Chiba","institution_ids":["https://openalex.org/I159385669"]},{"raw_affiliation_string":"First Department of Internal Medicine, School of Medicine, Fukuoka University, Fukuoka","institution_ids":["https://openalex.org/I31784960"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":5500,"currency":"USD","value_usd":5500},"apc_paid":null,"fwci":3.1428,"has_fulltext":false,"cited_by_count":134,"citation_normalized_percentile":{"value":0.91385442,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":89,"max":99},"biblio":{"volume":"97","issue":"3","first_page":"708","last_page":"713"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10685","display_name":"Viral-associated cancers and disorders","score":0.9276999831199646,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10685","display_name":"Viral-associated cancers and disorders","score":0.9276999831199646,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10185","display_name":"Lymphoma Diagnosis and Treatment","score":0.045899998396635056,"subfield":{"id":"https://openalex.org/subfields/2734","display_name":"Pathology and Forensic Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11020","display_name":"Immune Cell Function and Interaction","score":0.009999999776482582,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/epstein-barr-virus","display_name":"Epstein-Barr virus","score":0.9470000267028809},{"id":"https://openalex.org/keywords/cell-line-establishment","display_name":"cell line establishment","score":0.8169999718666077},{"id":"https://openalex.org/keywords/nk-cell-phenotype","display_name":"NK cell phenotype","score":0.7239999771118164},{"id":"https://openalex.org/keywords/t-cell-receptor-gene-rearrangement","display_name":"T-cell receptor gene rearrangement","score":0.8059999942779541},{"id":"https://openalex.org/keywords/immunoglobulin-heavy-chain-genes","display_name":"immunoglobulin heavy chain genes","score":0.875},{"id":"https://openalex.org/keywords/interleukin-2","display_name":"interleukin-2","score":0.6890000104904175},{"id":"https://openalex.org/keywords/cancer-cell-lines","display_name":"cancer cell lines","score":0.35600000619888306}],"concepts":[{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.6438720226287842},{"id":"https://openalex.org/C167672396","wikidata":"https://www.wikidata.org/wiki/Q417800","display_name":"CD8","level":3,"score":0.6332800388336182},{"id":"https://openalex.org/C19317047","wikidata":"https://www.wikidata.org/wiki/Q412037","display_name":"T-cell receptor","level":4,"score":0.6211778521537781},{"id":"https://openalex.org/C2778102761","wikidata":"https://www.wikidata.org/wiki/Q332181","display_name":"Natural killer cell","level":4,"score":0.6035122275352478},{"id":"https://openalex.org/C114684123","wikidata":"https://www.wikidata.org/wiki/Q419458","display_name":"CD3","level":4,"score":0.5328453183174133},{"id":"https://openalex.org/C2778957590","wikidata":"https://www.wikidata.org/wiki/Q798033","display_name":"CD19","level":3,"score":0.508487343788147},{"id":"https://openalex.org/C2776090121","wikidata":"https://www.wikidata.org/wiki/Q193529","display_name":"T cell","level":3,"score":0.50422203540802},{"id":"https://openalex.org/C2992511266","wikidata":"https://www.wikidata.org/wiki/Q1093098","display_name":"Gene rearrangement","level":3,"score":0.4940986931324005},{"id":"https://openalex.org/C2777589544","wikidata":"https://www.wikidata.org/wiki/Q7667896","display_name":"T-cell lymphoma","level":3,"score":0.4792930483818054},{"id":"https://openalex.org/C2779338263","wikidata":"https://www.wikidata.org/wiki/Q208414","display_name":"Lymphoma","level":2,"score":0.43116337060928345},{"id":"https://openalex.org/C81885089","wikidata":"https://www.wikidata.org/wiki/Q189082","display_name":"Cell culture","level":2,"score":0.4118143320083618},{"id":"https://openalex.org/C153911025","wikidata":"https://www.wikidata.org/wiki/Q7202","display_name":"Molecular biology","level":1,"score":0.4056289792060852},{"id":"https://openalex.org/C154317977","wikidata":"https://www.wikidata.org/wiki/Q376266","display_name":"Cytotoxic T cell","level":3,"score":0.3710166811943054},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.3418678343296051},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.3403393626213074},{"id":"https://openalex.org/C553184892","wikidata":"https://www.wikidata.org/wiki/Q1141429","display_name":"Flow cytometry","level":2,"score":0.3039529323577881},{"id":"https://openalex.org/C147483822","wikidata":"https://www.wikidata.org/wiki/Q103537","display_name":"Antigen","level":2,"score":0.2659255266189575},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.1297965943813324},{"id":"https://openalex.org/C8891405","wikidata":"https://www.wikidata.org/wiki/Q1059","display_name":"Immune system","level":2,"score":0.09299945831298828},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.07832172513008118},{"id":"https://openalex.org/C202751555","wikidata":"https://www.wikidata.org/wiki/Q221681","display_name":"In vitro","level":2,"score":0.06863579154014587}],"mesh":[{"descriptor_ui":"D002461","descriptor_name":"Cell Line, Transformed","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D002999","descriptor_name":"Clone Cells","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004854","descriptor_name":"Herpesvirus 4, Human","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005803","descriptor_name":"Genes, Immunoglobulin","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006103","descriptor_name":"Granuloma, Lethal Midline","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D006103","descriptor_name":"Granuloma, Lethal Midline","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007694","descriptor_name":"Killer Cells, Natural","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":false},{"descriptor_ui":"D007694","descriptor_name":"Killer Cells, Natural","qualifier_ui":"Q000821","qualifier_name":"virology","is_major_topic":true},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013601","descriptor_name":"T-Lymphocytes","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":false},{"descriptor_ui":"D013601","descriptor_name":"T-Lymphocytes","qualifier_ui":"Q000821","qualifier_name":"virology","is_major_topic":true},{"descriptor_ui":"D015139","descriptor_name":"Blotting, Southern","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015329","descriptor_name":"Gene Rearrangement, T-Lymphocyte","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016130","descriptor_name":"Immunophenotyping","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016131","descriptor_name":"Lymphocyte Subsets","qualifier_ui":"Q000145","qualifier_name":"classification","is_major_topic":false},{"descriptor_ui":"D016692","descriptor_name":"Receptors, Antigen, T-Cell, gamma-delta","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D020031","descriptor_name":"Epstein-Barr Virus Infections","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D020031","descriptor_name":"Epstein-Barr Virus Infections","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1182/blood.v97.3.708","doi":"https://doi.org/10.1182/blood.v97.3.708","is_oa":false,"landing_page_url":"https://doi.org/10.1182/blood.v97.3.708","pdf_url":null,"source":{"id":"https://openalex.org/S200071133","display_name":"Blood","issn_l":"0006-4971","issn":["0006-4971","1528-0020"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Blood","raw_type":"journal-article"},{"id":"pmid:11157488","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/11157488","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Blood","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.9537000060081482}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":59,"referenced_works":["https://openalex.org/W13386708","https://openalex.org/W15966455","https://openalex.org/W161786533","https://openalex.org/W171001763","https://openalex.org/W172662817","https://openalex.org/W1590095109","https://openalex.org/W1965526826","https://openalex.org/W1972992388","https://openalex.org/W1975164056","https://openalex.org/W1976653673","https://openalex.org/W1980634883","https://openalex.org/W1982289372","https://openalex.org/W1983739173","https://openalex.org/W1984408221","https://openalex.org/W1984724325","https://openalex.org/W1985075051","https://openalex.org/W1986561098","https://openalex.org/W1987570848","https://openalex.org/W1990135274","https://openalex.org/W1993659659","https://openalex.org/W1999663037","https://openalex.org/W2000911067","https://openalex.org/W2005170589","https://openalex.org/W2008140811","https://openalex.org/W2009813063","https://openalex.org/W2017214831","https://openalex.org/W2024755855","https://openalex.org/W2026540048","https://openalex.org/W2034521989","https://openalex.org/W2040524492","https://openalex.org/W2042670391","https://openalex.org/W2047193748","https://openalex.org/W2053677240","https://openalex.org/W2057363850","https://openalex.org/W2057957979","https://openalex.org/W2058386514","https://openalex.org/W2064567786","https://openalex.org/W2066573525","https://openalex.org/W2076559832","https://openalex.org/W2077457701","https://openalex.org/W2084408104","https://openalex.org/W2087099073","https://openalex.org/W2092450783","https://openalex.org/W2099151586","https://openalex.org/W2104226988","https://openalex.org/W2104307198","https://openalex.org/W2107202569","https://openalex.org/W2111411380","https://openalex.org/W2111849687","https://openalex.org/W2121040659","https://openalex.org/W2156277822","https://openalex.org/W2266123463","https://openalex.org/W2273379160","https://openalex.org/W2297036705","https://openalex.org/W2300946888","https://openalex.org/W2409952111","https://openalex.org/W2444327935","https://openalex.org/W3129040864","https://openalex.org/W4300996691"],"related_works":["https://openalex.org/W1990135274","https://openalex.org/W7009484622","https://openalex.org/W2365821131","https://openalex.org/W2111411380","https://openalex.org/W1985075051","https://openalex.org/W2077457701","https://openalex.org/W2118543832","https://openalex.org/W2023998928","https://openalex.org/W15966455","https://openalex.org/W2083329634"],"abstract_inverted_index":{"Studies":[0],"on":[1],"nasal":[2,192,220],"T/natural":[3],"killer":[4],"(NK)-cell":[5],"lymphoma":[6],"have":[7],"been":[8,217],"hampered":[9],"by":[10,56],"its":[11,167],"tendency":[12],"to":[13,27,33,113,171,229],"cause":[14],"necrosis.":[15],"Thus,":[16,119],"the":[17,105,120,127,143,152,179,183,197,230],"establishment":[18,184],"of":[19,22,40,58,100,148,182,185,191,224,237],"cell":[20,35,51,106,121,186,194,222],"lines":[21,36,107,122,187],"this":[23,41,212],"neoplasm":[24],"would":[25],"seem":[26],"be":[28,172],"valuable.":[29],"This":[30,177],"study":[31],"attempted":[32],"establish":[34],"from":[37,124,188],"primary":[38,128,189],"lesions":[39,190],"tumor,":[42],"and":[43,54,104,138,161,164,196,208,242],"successfully":[44],"obtained":[45],"2":[46,205],"novel":[47],"Epstein-Barr":[48],"virus":[49],"(EBV)-positive":[50],"lines,":[52],"SNK-6":[53,67,134,146],"SNT-8,":[55],"means":[57],"high-dose":[59],"recombinant":[60],"interleukin":[61],"2.":[62],"Flow":[63],"cytometry":[64],"showed":[65,132],"that":[66,133,145,200,219],"had":[68,108,135,156],"an":[69],"NK-cell":[70,149],"phenotype,":[71,168],"CD3-":[72],"CD4-":[73,87],"CD8-":[74,88],"CD19-":[75,89],"CD56+":[76,90],"T-cell":[77,175],"receptor":[78],"(TCR)":[79],"alpha/beta-":[80,92],"TCR":[81,91,93,137,158],"gamma/delta-,":[82],"whereas":[83],"SNT-8":[84,155,169],"was":[85,147],"CD3+":[86],"gamma/delta+.":[94],"These":[95],"were":[96],"consistent":[97],"with":[98,166],"immunophenotypes":[99],"their":[101,116],"original":[102,117],"tumors,":[103],"monoclonal":[109],"EBV":[110],"clones":[111],"identical":[112],"ones":[114],"in":[115,211],"tumors.":[118],"developed":[123],"cells":[125],"forming":[126],"lesions.":[129],"Genotypic":[130],"analysis":[131],"unrearranged":[136],"immunoglobulin":[139],"heavy-chain":[140],"genes,":[141,163],"supporting":[142],"conclusion":[144],"lineage.":[150],"On":[151],"other":[153],"hand,":[154],"rearranged":[157],"beta-,":[159],"gamma-,":[160],"delta-chain":[162],"together":[165],"proved":[170],"a":[173],"gammadelta":[174,209],"line.":[176],"is":[178],"first":[180],"report":[181],"T/NK":[193,221],"lymphomas,":[195],"results":[198],"demonstrated":[199],"there":[201],"are":[202],"at":[203],"least":[204],"lineages,":[206],"NK-":[207],"T-cell,":[210],"neoplasm.":[213],"Moreover,":[214],"it":[215],"has":[216],"suggested":[218],"lymphomas":[223],"these":[225],"lineages":[226],"may":[227],"belong":[228],"same":[231],"clinicopathologic":[232],"entity":[233],"because":[234],"both":[235],"types":[236],"cases":[238],"shared":[239],"common":[240],"clinical":[241],"histopathologic":[243],"features.":[244]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":3},{"year":2024,"cited_by_count":4},{"year":2023,"cited_by_count":4},{"year":2022,"cited_by_count":6},{"year":2021,"cited_by_count":8},{"year":2020,"cited_by_count":7},{"year":2019,"cited_by_count":6},{"year":2018,"cited_by_count":8},{"year":2017,"cited_by_count":3},{"year":2016,"cited_by_count":6},{"year":2015,"cited_by_count":9},{"year":2014,"cited_by_count":1},{"year":2013,"cited_by_count":6},{"year":2012,"cited_by_count":6}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}