{"id":"https://openalex.org/W1968625705","doi":"https://doi.org/10.1118/1.4889399","title":"WE\u2010D\u2010BRF\u201001: FEATURED PRESENTATION \u2013 Investigating Particle Track Structures Using Fluorescent Nuclear Track Detectors and Monte Carlo Simulations","display_name":"WE\u2010D\u2010BRF\u201001: FEATURED PRESENTATION \u2013 Investigating Particle Track Structures Using Fluorescent Nuclear Track Detectors and Monte Carlo Simulations","publication_year":2014,"publication_date":"2014-05-29","ids":{"openalex":"https://openalex.org/W1968625705","doi":"https://doi.org/10.1118/1.4889399","mag":"1968625705"},"language":"en","primary_location":{"id":"doi:10.1118/1.4889399","doi":"https://doi.org/10.1118/1.4889399","is_oa":false,"landing_page_url":"https://doi.org/10.1118/1.4889399","pdf_url":null,"source":{"id":"https://openalex.org/S95522064","display_name":"Medical Physics","issn_l":"0094-2405","issn":["0094-2405","1522-8541","2473-4209"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Medical Physics","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5090315641","display_name":"S Dowdell","orcid":"https://orcid.org/0000-0001-7996-319X","observed_orcids":["https://orcid.org/0000-0001-7996-319X"]},"institutions":[{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I4210087915","display_name":"Massachusetts General Hospital","ror":"https://ror.org/002pd6e78","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210087915","https://openalex.org/I48633490"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"S Dowdell","raw_affiliation_strings":["Department of Radiation Oncology, Massachusetts General Hospital & Harvard Medical School, Boston, MA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiation Oncology, Massachusetts General Hospital & Harvard Medical School, Boston, MA","institution_ids":["https://openalex.org/I136199984","https://openalex.org/I4210087915"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5041376065","display_name":"Steffen Greilich","orcid":"https://orcid.org/0000-0001-6237-7936","observed_orcids":["https://orcid.org/0000-0001-6237-7936"]},"institutions":[{"id":"https://openalex.org/I17937529","display_name":"German Cancer Research Center","ror":"https://ror.org/04cdgtt98","country_code":"DE","type":"facility","lineage":["https://openalex.org/I1305996414","https://openalex.org/I17937529"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"S Greilich","raw_affiliation_strings":["Division of Medical Physics in Radiation Oncology, DKFZ \u2013 German Cancer Research Center, Heidelberg, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Medical Physics in Radiation Oncology, DKFZ \u2013 German Cancer Research Center, Heidelberg, Germany","institution_ids":["https://openalex.org/I17937529"]}]},{"author_position":"middle","author":{"id":null,"display_name":"F Zimmerman","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I17937529","display_name":"German Cancer Research Center","ror":"https://ror.org/04cdgtt98","country_code":"DE","type":"facility","lineage":["https://openalex.org/I1305996414","https://openalex.org/I17937529"]},{"id":"https://openalex.org/I4210087915","display_name":"Massachusetts General Hospital","ror":"https://ror.org/002pd6e78","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210087915","https://openalex.org/I48633490"]}],"countries":["DE","US"],"is_corresponding":false,"raw_author_name":"F Zimmerman","raw_affiliation_strings":["Department of Radiation Oncology, Massachusetts General Hospital & Harvard Medical School, Boston, MA","Division of Medical Physics in Radiation Oncology, DKFZ \u2013 German Cancer Research Center, Heidelberg, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiation Oncology, Massachusetts General Hospital & Harvard Medical School, Boston, MA","institution_ids":["https://openalex.org/I136199984","https://openalex.org/I4210087915"]},{"raw_affiliation_string":"Division of Medical Physics in Radiation Oncology, DKFZ \u2013 German Cancer Research Center, Heidelberg, Germany","institution_ids":["https://openalex.org/I17937529"]}]},{"author_position":"middle","author":{"id":null,"display_name":"C Evans","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I4210087915","display_name":"Massachusetts General Hospital","ror":"https://ror.org/002pd6e78","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210087915","https://openalex.org/I48633490"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"C Evans","raw_affiliation_strings":["Wellman Center for Photomedicine, Massachusetts General Hospital & Harvard Medical School, Boston, MA","Wellman Center for Photomedicine; Massachusetts General Hospital and Harvard Medical School; Boston MA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Wellman Center for Photomedicine, Massachusetts General Hospital & Harvard Medical School, Boston, MA","institution_ids":["https://openalex.org/I136199984","https://openalex.org/I4210087915"]},{"raw_affiliation_string":"Wellman Center for Photomedicine; Massachusetts General Hospital and Harvard Medical School; Boston MA","institution_ids":["https://openalex.org/I136199984","https://openalex.org/I4210087915"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5037938903","display_name":"Harald Paganetti","orcid":"https://orcid.org/0000-0002-6257-2413","observed_orcids":["https://orcid.org/0000-0002-6257-2413"]},"institutions":[{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I4210087915","display_name":"Massachusetts General Hospital","ror":"https://ror.org/002pd6e78","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210087915","https://openalex.org/I48633490"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"H Paganetti","raw_affiliation_strings":["Department of Radiation Oncology, Massachusetts General Hospital & Harvard Medical School, Boston, MA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiation Oncology, Massachusetts General Hospital & Harvard Medical School, Boston, MA","institution_ids":["https://openalex.org/I136199984","https://openalex.org/I4210087915"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5023199362","display_name":"Jan Schuemann","orcid":"https://orcid.org/0000-0002-7554-8818","observed_orcids":["https://orcid.org/0000-0002-7554-8818"]},"institutions":[{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I4210087915","display_name":"Massachusetts General Hospital","ror":"https://ror.org/002pd6e78","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210087915","https://openalex.org/I48633490"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"J Schuemann","raw_affiliation_strings":["Department of Radiation Oncology, Massachusetts General Hospital & Harvard Medical School, Boston, MA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiation Oncology, Massachusetts General Hospital & Harvard Medical School, Boston, MA","institution_ids":["https://openalex.org/I136199984","https://openalex.org/I4210087915"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":3,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":3360,"currency":"USD","value_usd":3360},"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.10444283,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"41","issue":"6Part29","first_page":"495","last_page":"495"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11176","display_name":"Radiation Therapy and Dosimetry","score":0.9810000061988831,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11176","display_name":"Radiation Therapy and Dosimetry","score":0.9810000061988831,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11044","display_name":"Particle Detector Development and Performance","score":0.006899999920278788,"subfield":{"id":"https://openalex.org/subfields/3106","display_name":"Nuclear and High Energy Physics"},"field":{"id":"https://openalex.org/fields/31","display_name":"Physics and Astronomy"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T12166","display_name":"Ion-surface interactions and analysis","score":0.0034000000450760126,"subfield":{"id":"https://openalex.org/subfields/2206","display_name":"Computational Mechanics"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/fluorescent-nuclear-track-detectors","display_name":"fluorescent nuclear track detectors","score":0.9860000014305115},{"id":"https://openalex.org/keywords/radiobiology","display_name":"radiation biology","score":0.6610000133514404},{"id":"https://openalex.org/keywords/monte-carlo-simulation","display_name":"Monte Carlo simulation","score":0.7210000157356262},{"id":"https://openalex.org/keywords/geant4","display_name":"Geant4","score":0.7269999980926514},{"id":"https://openalex.org/keywords/geant4-dna","display_name":"Geant4-DNA","score":0.7599999904632568},{"id":"https://openalex.org/keywords/gold-ion-irradiation","display_name":"gold ion irradiation","score":0.75},{"id":"https://openalex.org/keywords/carbon-ion-irradiation","display_name":"carbon ion irradiation","score":0.9929999709129333},{"id":"https://openalex.org/keywords/track-reconstruction","display_name":"track reconstruction","score":0.5609999895095825}],"concepts":[{"id":"https://openalex.org/C19499675","wikidata":"https://www.wikidata.org/wiki/Q232207","display_name":"Monte Carlo method","level":2,"score":0.7707867622375488},{"id":"https://openalex.org/C94915269","wikidata":"https://www.wikidata.org/wiki/Q1834857","display_name":"Detector","level":2,"score":0.5650779604911804},{"id":"https://openalex.org/C67649825","wikidata":"https://www.wikidata.org/wiki/Q196538","display_name":"Microscope","level":2,"score":0.5616821050643921},{"id":"https://openalex.org/C89992363","wikidata":"https://www.wikidata.org/wiki/Q5961558","display_name":"Track (disk drive)","level":2,"score":0.556242823600769},{"id":"https://openalex.org/C71085134","wikidata":"https://www.wikidata.org/wiki/Q1672061","display_name":"Ion track","level":3,"score":0.5502946972846985},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.5270942449569702},{"id":"https://openalex.org/C120665830","wikidata":"https://www.wikidata.org/wiki/Q14620","display_name":"Optics","level":1,"score":0.4483548104763031},{"id":"https://openalex.org/C33390570","wikidata":"https://www.wikidata.org/wiki/Q188463","display_name":"Spectrometer","level":2,"score":0.4186646342277527},{"id":"https://openalex.org/C147120987","wikidata":"https://www.wikidata.org/wiki/Q2225","display_name":"Electron","level":2,"score":0.4107380509376526},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.3474026322364807},{"id":"https://openalex.org/C185544564","wikidata":"https://www.wikidata.org/wiki/Q81197","display_name":"Nuclear physics","level":1,"score":0.30257922410964966},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.2896530032157898},{"id":"https://openalex.org/C111337013","wikidata":"https://www.wikidata.org/wiki/Q2737837","display_name":"Irradiation","level":2,"score":0.26148027181625366},{"id":"https://openalex.org/C105795698","wikidata":"https://www.wikidata.org/wiki/Q12483","display_name":"Statistics","level":1,"score":0.08934596180915833},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.08179652690887451},{"id":"https://openalex.org/C111919701","wikidata":"https://www.wikidata.org/wiki/Q9135","display_name":"Operating system","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1118/1.4889399","doi":"https://doi.org/10.1118/1.4889399","is_oa":false,"landing_page_url":"https://doi.org/10.1118/1.4889399","pdf_url":null,"source":{"id":"https://openalex.org/S95522064","display_name":"Medical Physics","issn_l":"0094-2405","issn":["0094-2405","1522-8541","2473-4209"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Medical Physics","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W6922264034","https://openalex.org/W2056970609","https://openalex.org/W2523975549","https://openalex.org/W3085598030","https://openalex.org/W3166828704","https://openalex.org/W2563723323","https://openalex.org/W2602417996","https://openalex.org/W2598014980","https://openalex.org/W2131988667","https://openalex.org/W2048698592"],"abstract_inverted_index":{"Purpose:":[0],"To":[1],"report":[2],"on":[3,34,104,280],"the":[4,8,15,35,54,84,90,116,122,130,144,148,173,177,207,211,224,226,245,249,254,261,265,269,282,293],"efforts":[5],"funded":[6],"by":[7,124],"AAPM":[9],"seed":[10,266],"funding":[11,149,212,267],"grant":[12],"to":[13,52,88,92,163,220,243,285,292],"develop":[14],"basis":[16],"for":[17],"fluorescent":[18],"nuclear":[19],"track":[20,82,191,238,246,289],"detector":[21],"(FNTD)":[22],"based":[23],"radiobiological":[24],"experiments":[25],"in":[26,44,134,187,206,218,232,264],"combination":[27],"with":[28,61,69,115,189,199,223],"dedicated":[29],"Monte":[30],"Carlo":[31],"simulations":[32,111,239],"(MCS)":[33],"nanometer":[36,294],"scale.":[37],"Methods:":[38],"Two":[39,47,108],"confocal":[40],"microscopes":[41],"were":[42,50,97,112],"utilized":[43],"this":[45],"study.":[46],"FNTD":[48,59,137,272],"samples":[49],"used":[51,87,242],"find":[53],"optimal":[55],"microscope":[56,167,198],"settings,":[57],"one":[58,67,114],"irradiated":[60,68],"11.1":[62],"MeV/u":[63,71],"Gold":[64],"ions":[65],"and":[66,120,138,251,274],"428.77":[70],"Carbon":[72,185],"ions.":[73],"The":[74,234],"first":[75,145],"sample":[76],"provided":[77],"a":[78,126,135,139],"brightly":[79],"luminescent":[80],"central":[81],"while":[83],"latter":[85],"is":[86,169],"test":[89],"capabilities":[91,156,202],"observe":[93],"secondary":[94],"electrons.":[95],"MCS":[96,288],"performed":[98],"using":[99,129],"TOPAS":[100],"beta9":[101],"version,":[102],"layered":[103],"top":[105],"of":[106,110,147,157,193,210,253,271],"Geant4.9.6p02.":[107],"sets":[109],"performed,":[113],"Geant4\u2010DNA":[117,237],"physics":[118,132],"list":[119,133],"approximating":[121],"FNTDs":[123,158],"water,":[125],"second":[127,197,208],"set":[128,263],"Penelope":[131],"water\u2010approximated":[136],"aluminum\u2010oxide":[140],"FNTD.":[141],"Results:":[142],"Within":[143],"half":[146,209],"period,":[150,213],"we":[151,181,214],"have":[152,228,259],"successfully":[153,229],"established":[154],"readout":[155,201,273,283],"at":[159,176],"our":[160,166,287],"institute.":[161],"Due":[162],"technical":[164],"limitations,":[165],"setup":[168,270],"significantly":[170],"different":[171],"from":[172,248],"approach":[174],"implemented":[175],"DKFZ,":[178],"Germany.":[179],"However,":[180],"can":[182,240],"clearly":[183],"reconstruct":[184,244],"tracks":[186,231],"3D":[188],"electron":[190],"resolution":[192,284],"200":[194],"nm.":[195],"A":[196],"superior":[200],"will":[203,278],"be":[204,241],"tested":[205],"expect":[215],"an":[216],"improvement":[217],"signal":[219],"background":[221],"ratio":[222],"same":[225],"resolution.We":[227],"simulated":[230],"FNTDs.":[233],"more":[235],"accurate":[236],"energy":[247],"size":[250],"brightness":[252],"observed":[255],"tracks.":[256],"Conclusion:":[257],"We":[258,277],"achieved":[260],"goals":[262],"proposal:":[268],"simulation":[275],"capabilities.":[276],"work":[279],"improving":[281],"validate":[286],"structures":[290],"down":[291],"scales.":[295]},"counts_by_year":[],"updated_date":"2026-10-30T12:39:25.321706","created_date":"2016-06-24T00:00:00"}