{"id":"https://openalex.org/W1968578554","doi":"https://doi.org/10.4321/s0004-06142006001000011","title":"Metodolog\u00eda diagnostica ante la recidiva bioqu\u00edmica despu\u00e9s de prostatectom\u00eda radical","display_name":"Metodolog\u00eda diagnostica ante la recidiva bioqu\u00edmica despu\u00e9s de prostatectom\u00eda radical","publication_year":2006,"publication_date":"2006-12-01","ids":{"openalex":"https://openalex.org/W1968578554","doi":"https://doi.org/10.4321/s0004-06142006001000011","mag":"1968578554","pmid":"https://pubmed.ncbi.nlm.nih.gov/17283717"},"language":"es","primary_location":{"id":"doi:10.4321/s0004-06142006001000011","doi":"https://doi.org/10.4321/s0004-06142006001000011","is_oa":false,"landing_page_url":"https://doi.org/10.4321/s0004-06142006001000011","pdf_url":null,"source":{"id":"https://openalex.org/S2750677747","display_name":"Archivos Espa\u00f1oles de Urolog\u00eda","issn_l":"0004-0614","issn":["0004-0614","1576-8260"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","medline","norway-1","poland-20","russia-white-list-4"],"host_organization":"https://openalex.org/P4310312277","host_organization_name":"SciELO","host_organization_lineage":["https://openalex.org/P4310312277"],"host_organization_lineage_names":["SciELO"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Archivos Espa\u00f1oles de Urolog\u00eda (Ed. impresa)","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"http://scielo.isciii.es/scielo.php?script=sci_arttext&pid=S0004-06142006001000011","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5112890510","display_name":"A. Collado","orcid":"https://orcid.org/0000-0002-5392-0543","observed_orcids":["https://orcid.org/0000-0002-5392-0543"]},"institutions":[{"id":"https://openalex.org/I4210103093","display_name":"Fundaci\u00f3n Instituto Valenciano de Oncolog\u00eda","ror":"https://ror.org/01fh9k283","country_code":"ES","type":"healthcare","lineage":["https://openalex.org/I4210103093"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"Argimiro Collado Serra","raw_affiliation_strings":["Instituto Valenciano de Ontolog\u00eda (IVO), Valencia, Espa\u00f1a"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Instituto Valenciano de Ontolog\u00eda (IVO), Valencia, Espa\u00f1a","institution_ids":["https://openalex.org/I4210103093"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5061392341","display_name":"Eduardo Solsona Narb\u00f3n","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210103093","display_name":"Fundaci\u00f3n Instituto Valenciano de Oncolog\u00eda","ror":"https://ror.org/01fh9k283","country_code":"ES","type":"healthcare","lineage":["https://openalex.org/I4210103093"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"Eduardo Solsona Narb\u00f3n","raw_affiliation_strings":["Instituto Valenciano de Ontolog\u00eda (IVO), Valencia, Espa\u00f1a"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Instituto Valenciano de Ontolog\u00eda (IVO), Valencia, Espa\u00f1a","institution_ids":["https://openalex.org/I4210103093"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I4210103093"],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":2,"citation_normalized_percentile":{"value":0.13872478,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":94},"biblio":{"volume":"59","issue":"10","first_page":"1041","last_page":"52"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10124","display_name":"Prostate Cancer Diagnosis and Treatment","score":0.9955999851226807,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10124","display_name":"Prostate Cancer Diagnosis and Treatment","score":0.9955999851226807,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10543","display_name":"Prostate Cancer Treatment and Research","score":0.0027000000700354576,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10183","display_name":"Breast Cancer Treatment Studies","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/prostate-cancer","display_name":"prostate cancer","score":0.9269999861717224},{"id":"https://openalex.org/keywords/radical-prostatectomy","display_name":"radical prostatectomy","score":0.8799999952316284},{"id":"https://openalex.org/keywords/biochemical-recurrence","display_name":"biochemical recurrence","score":0.9990000128746033},{"id":"https://openalex.org/keywords/psa-monitoring","display_name":"PSA monitoring","score":0.4690000116825104},{"id":"https://openalex.org/keywords/psa-velocity","display_name":"PSA velocity","score":0.7440000176429749},{"id":"https://openalex.org/keywords/psa-doubling-time","display_name":"PSA doubling time","score":0.996999979019165},{"id":"https://openalex.org/keywords/gleason-score","display_name":"Gleason score","score":0.9129999876022339},{"id":"https://openalex.org/keywords/radiotherapy","display_name":"radiotherapy","score":0.722000002861023},{"id":"https://openalex.org/keywords/diagnostic-methods","display_name":"diagnostic methods","score":0.48899999260902405}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.925420880317688},{"id":"https://openalex.org/C2779466945","wikidata":"https://www.wikidata.org/wiki/Q1765251","display_name":"Prostatectomy","level":4,"score":0.8360716700553894},{"id":"https://openalex.org/C2777008409","wikidata":"https://www.wikidata.org/wiki/Q4914714","display_name":"Biochemical recurrence","level":5,"score":0.8072501420974731},{"id":"https://openalex.org/C2780192828","wikidata":"https://www.wikidata.org/wiki/Q181257","display_name":"Prostate cancer","level":3,"score":0.6518387198448181},{"id":"https://openalex.org/C126894567","wikidata":"https://www.wikidata.org/wiki/Q105650","display_name":"Urology","level":1,"score":0.5551130771636963},{"id":"https://openalex.org/C146357865","wikidata":"https://www.wikidata.org/wiki/Q1123245","display_name":"Stage (stratigraphy)","level":2,"score":0.4613708257675171},{"id":"https://openalex.org/C509974204","wikidata":"https://www.wikidata.org/wiki/Q180507","display_name":"Radiation therapy","level":2,"score":0.43897706270217896},{"id":"https://openalex.org/C48900799","wikidata":"https://www.wikidata.org/wiki/Q1424376","display_name":"Doubling time","level":3,"score":0.4363269507884979},{"id":"https://openalex.org/C2908647359","wikidata":"https://www.wikidata.org/wiki/Q2625603","display_name":"Population","level":2,"score":0.41782882809638977},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.3287493586540222},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.2694748044013977},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.26786670088768005},{"id":"https://openalex.org/C99454951","wikidata":"https://www.wikidata.org/wiki/Q932068","display_name":"Environmental health","level":1,"score":0.0},{"id":"https://openalex.org/C151730666","wikidata":"https://www.wikidata.org/wiki/Q7205","display_name":"Paleontology","level":1,"score":0.0},{"id":"https://openalex.org/C202751555","wikidata":"https://www.wikidata.org/wiki/Q221681","display_name":"In vitro","level":2,"score":0.0},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.0},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009364","descriptor_name":"Neoplasm Recurrence, Local","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D009364","descriptor_name":"Neoplasm Recurrence, Local","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":true},{"descriptor_ui":"D011379","descriptor_name":"Prognosis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011468","descriptor_name":"Prostatectomy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D011471","descriptor_name":"Prostatic Neoplasms","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D011471","descriptor_name":"Prostatic Neoplasms","qualifier_ui":"Q000601","qualifier_name":"surgery","is_major_topic":true},{"descriptor_ui":"D016609","descriptor_name":"Neoplasms, Second Primary","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D016609","descriptor_name":"Neoplasms, Second Primary","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":true},{"descriptor_ui":"D017430","descriptor_name":"Prostate-Specific Antigen","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true}],"locations_count":4,"locations":[{"id":"doi:10.4321/s0004-06142006001000011","doi":"https://doi.org/10.4321/s0004-06142006001000011","is_oa":false,"landing_page_url":"https://doi.org/10.4321/s0004-06142006001000011","pdf_url":null,"source":{"id":"https://openalex.org/S2750677747","display_name":"Archivos Espa\u00f1oles de Urolog\u00eda","issn_l":"0004-0614","issn":["0004-0614","1576-8260"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","medline","norway-1","poland-20","russia-white-list-4"],"host_organization":"https://openalex.org/P4310312277","host_organization_name":"SciELO","host_organization_lineage":["https://openalex.org/P4310312277"],"host_organization_lineage_names":["SciELO"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Archivos Espa\u00f1oles de Urolog\u00eda (Ed. impresa)","raw_type":"journal-article"},{"id":"pmid:17283717","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/17283717","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Archivos espanoles de urologia","raw_type":"English Abstract"},{"id":"pmh:oai:hispana.mcu.es:5992385","doi":null,"is_oa":true,"landing_page_url":"http://scielo.isciii.es/scielo.php?script=sci_arttext&pid=S0004-06142006001000011","pdf_url":null,"source":{"id":"https://openalex.org/S4377196108","display_name":"Hispana","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"journal article"},{"id":"pmh:oai:scielo:S0004-06142006001000011","doi":null,"is_oa":false,"landing_page_url":"http://scielo.isciii.es/scielo.php?script=sci_arttext&pid=S0004-06142006001000011","pdf_url":null,"source":{"id":"https://openalex.org/S4306402135","display_name":"Scientific Electronic library online (Sciences Carlos III Health Institute)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I2801357902","host_organization_name":"Instituto de Salud Carlos III","host_organization_lineage":["https://openalex.org/I2801357902"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Archivos Espa\u00c3\u00b1oles de Urolog\u00c3\u00ada (Ed. impresa) v.59 n.10 2006","raw_type":"journal article"}],"best_oa_location":{"id":"pmh:oai:hispana.mcu.es:5992385","doi":null,"is_oa":true,"landing_page_url":"http://scielo.isciii.es/scielo.php?script=sci_arttext&pid=S0004-06142006001000011","pdf_url":null,"source":{"id":"https://openalex.org/S4377196108","display_name":"Hispana","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"journal article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.9789000153541565,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":39,"referenced_works":["https://openalex.org/W3215447","https://openalex.org/W11097077","https://openalex.org/W69788875","https://openalex.org/W127182478","https://openalex.org/W1965053728","https://openalex.org/W1968083949","https://openalex.org/W1972667933","https://openalex.org/W1982757300","https://openalex.org/W1983747681","https://openalex.org/W1990532490","https://openalex.org/W1999409811","https://openalex.org/W2005998463","https://openalex.org/W2007821528","https://openalex.org/W2009576939","https://openalex.org/W2014145760","https://openalex.org/W2015255922","https://openalex.org/W2018998854","https://openalex.org/W2019001064","https://openalex.org/W2021818851","https://openalex.org/W2023475404","https://openalex.org/W2037698053","https://openalex.org/W2046873144","https://openalex.org/W2047784025","https://openalex.org/W2061332484","https://openalex.org/W2063610975","https://openalex.org/W2103003357","https://openalex.org/W2105947918","https://openalex.org/W2117299097","https://openalex.org/W2136220787","https://openalex.org/W2137491531","https://openalex.org/W2334866400","https://openalex.org/W2790909219","https://openalex.org/W4230446008","https://openalex.org/W4237325177","https://openalex.org/W4238915220","https://openalex.org/W4245326763","https://openalex.org/W4249663626","https://openalex.org/W4300900655","https://openalex.org/W4301961722"],"related_works":["https://openalex.org/W1995051622","https://openalex.org/W2067376756","https://openalex.org/W1984181310","https://openalex.org/W2036317783","https://openalex.org/W1966985085","https://openalex.org/W2969424959","https://openalex.org/W7140249052","https://openalex.org/W2075485620","https://openalex.org/W2019827701","https://openalex.org/W4205324698"],"abstract_inverted_index":{"Prostate":[0],"cancer":[1],"is":[2,65,72,79,85,139],"one":[3,103],"of":[4,9,28,40,51,126,128,150],"the":[5,10,29,43,59,74],"main":[6],"health":[7],"problems":[8],"male":[11],"population.":[12],"Radical":[13],"prostatectomy":[14,133],"has":[15],"demonstrated":[16],"to":[17,80,87,100,109],"have":[18],"an":[19],"excellent":[20],"long-term":[21],"cure":[22],"rate.":[23],"Nevertheless,":[24,137],"globally,":[25],"a":[26,34,48],"25%":[27],"operated":[30],"patients":[31,143],"will":[32,94],"suffer":[33],"PSA":[35,44,110,112,114],"increase":[36],"over":[37],"15":[38],"years":[39],"follow-up.":[41],"Generally,":[42],"value":[45],"associated":[46],"with":[47,144,159],"higher":[49],"risk":[50],"clinical":[52,77,83],"progression,":[53],"that":[54,142],"may":[55],"be":[56,88],"established":[57],"as":[58],"cut":[60],"point":[61],"for":[62,156],"biochemical":[63,70,129,145],"recurrence":[64,71,84,146],"0.4":[66],"ng/":[67],"ml.":[68],"Once":[69],"diagnosed,":[73],"most":[75],"important":[76],"data":[78],"determine":[81,95],"if":[82],"going":[86],"local":[89,157],"or":[90],"systemic,":[91],"because":[92],"it":[93,138],"treatment.":[96],"Main":[97],"parameters":[98],"helping":[99],"differentiate":[101],"between":[102],"and":[104,120],"another":[105],"are:":[106],"time":[107,116],"interval":[108],"increase,":[111],"velocity,":[113],"doubling":[115],"(PSA-DT),":[117],"pathologic":[118],"stage":[119],"specimen's":[121],"Gleason's":[122],"score.":[123],"The":[124],"possibilities":[125],"treatment":[127,158],"failure":[130],"after":[131],"radical":[132],"are":[134,153],"under":[135],"debate.":[136],"currently":[140],"considered":[141],"without":[147],"radiological":[148],"evidence":[149],"distant":[151],"metastases":[152],"ideal":[154],"candidates":[155],"radiotherapy.":[160]},"counts_by_year":[{"year":2021,"cited_by_count":1},{"year":2015,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}