{"id":"https://openalex.org/W1968470656","doi":"https://doi.org/10.1007/bf02556354","title":"Systemic effects of prostaglandin E2 on vertebral trabecular remodeling in beagles used in a healing study","display_name":"Systemic effects of prostaglandin E2 on vertebral trabecular remodeling in beagles used in a healing study","publication_year":1988,"publication_date":"1988-11-01","ids":{"openalex":"https://openalex.org/W1968470656","doi":"https://doi.org/10.1007/bf02556354","mag":"1968470656","pmid":"https://pubmed.ncbi.nlm.nih.gov/3135105"},"language":"en","primary_location":{"id":"doi:10.1007/bf02556354","doi":"https://doi.org/10.1007/bf02556354","is_oa":false,"landing_page_url":"https://doi.org/10.1007/bf02556354","pdf_url":null,"source":{"id":"https://openalex.org/S197748570","display_name":"Calcified Tissue International","issn_l":"0171-967X","issn":["0171-967X","1432-0827"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Calcified Tissue International","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5110255433","display_name":"Robert W. Norrdin","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I92446798","display_name":"Colorado State University","ror":"https://ror.org/03k1gpj17","country_code":"US","type":"education","lineage":["https://openalex.org/I92446798"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Robert W. Norrdin","raw_affiliation_strings":["Department of Pathology, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins 80523","Department of Pathology, Colorado State University, Fort Collins, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins 80523","institution_ids":["https://openalex.org/I92446798"]},{"raw_affiliation_string":"Department of Pathology, Colorado State University, Fort Collins, USA","institution_ids":["https://openalex.org/I92446798"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5113524101","display_name":"Mei Shu Shih","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I125749732","display_name":"Western University","ror":"https://ror.org/02grkyz14","country_code":"CA","type":"education","lineage":["https://openalex.org/I125749732"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Mei Shu Shih","raw_affiliation_strings":["Department of Pathology, Health Sciences Centre, The University of Western Ontario, London, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology, Health Sciences Centre, The University of Western Ontario, London, Canada","institution_ids":["https://openalex.org/I125749732"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":3990,"currency":"USD","value_usd":3990},"apc_paid":null,"fwci":0.659,"has_fulltext":false,"cited_by_count":68,"citation_normalized_percentile":{"value":0.6556114,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":97},"biblio":{"volume":"42","issue":"6","first_page":"363","last_page":"368"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11219","display_name":"Bone Metabolism and Diseases","score":0.9545999765396118,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11219","display_name":"Bone Metabolism and Diseases","score":0.9545999765396118,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10678","display_name":"Inflammatory mediators and NSAID effects","score":0.02019999921321869,"subfield":{"id":"https://openalex.org/subfields/2736","display_name":"Pharmacology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10071","display_name":"Bone health and osteoporosis research","score":0.015799999237060547,"subfield":{"id":"https://openalex.org/subfields/2732","display_name":"Orthopedics and Sports Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/prostaglandin-e2","display_name":"prostaglandin E2","score":1.0},{"id":"https://openalex.org/keywords/trabecular-bone-remodeling","display_name":"trabecular bone remodeling","score":0.8880000114440918},{"id":"https://openalex.org/keywords/bone-formation-rate","display_name":"bone formation rate","score":0.8130000233650208},{"id":"https://openalex.org/keywords/mineral-apposition-rate","display_name":"mineral apposition rate","score":0.9959999918937683},{"id":"https://openalex.org/keywords/bone-regeneration","display_name":"bone regeneration","score":0.574999988079071},{"id":"https://openalex.org/keywords/rib-fractures","display_name":"rib fractures","score":0.7739999890327454},{"id":"https://openalex.org/keywords/beagle","display_name":"beagle dogs","score":0.5839999914169312}],"concepts":[{"id":"https://openalex.org/C117866178","wikidata":"https://www.wikidata.org/wiki/Q321056","display_name":"Apposition","level":2,"score":0.8069030046463013},{"id":"https://openalex.org/C81880429","wikidata":"https://www.wikidata.org/wiki/Q2035067","display_name":"Osteoid","level":2,"score":0.7432360649108887},{"id":"https://openalex.org/C2777956040","wikidata":"https://www.wikidata.org/wiki/Q416554","display_name":"Prostaglandin E2","level":2,"score":0.697693407535553},{"id":"https://openalex.org/C170033053","wikidata":"https://www.wikidata.org/wiki/Q952019","display_name":"Bone remodeling","level":2,"score":0.6518374085426331},{"id":"https://openalex.org/C24998067","wikidata":"https://www.wikidata.org/wiki/Q4114622","display_name":"Stimulation","level":2,"score":0.6268320083618164},{"id":"https://openalex.org/C2993291840","wikidata":"https://www.wikidata.org/wiki/Q1121544","display_name":"Bone formation","level":2,"score":0.626516580581665},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.6232030987739563},{"id":"https://openalex.org/C2778260815","wikidata":"https://www.wikidata.org/wiki/Q917177","display_name":"Osteoblast","level":3,"score":0.5951998233795166},{"id":"https://openalex.org/C8337478","wikidata":"https://www.wikidata.org/wiki/Q1777289","display_name":"Bone healing","level":2,"score":0.5062979459762573},{"id":"https://openalex.org/C2909674915","wikidata":"https://www.wikidata.org/wiki/Q1851434","display_name":"Bone histomorphometry","level":4,"score":0.4607020914554596},{"id":"https://openalex.org/C2776412215","wikidata":"https://www.wikidata.org/wiki/Q180323","display_name":"Vertebra","level":2,"score":0.4597942531108856},{"id":"https://openalex.org/C2776033226","wikidata":"https://www.wikidata.org/wiki/Q828410","display_name":"Osteoclast","level":3,"score":0.4527975022792816},{"id":"https://openalex.org/C126894567","wikidata":"https://www.wikidata.org/wiki/Q105650","display_name":"Urology","level":1,"score":0.4156595766544342},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.4141996502876282},{"id":"https://openalex.org/C2780664492","wikidata":"https://www.wikidata.org/wiki/Q209717","display_name":"Prostaglandin","level":2,"score":0.4113306999206543},{"id":"https://openalex.org/C105702510","wikidata":"https://www.wikidata.org/wiki/Q514","display_name":"Anatomy","level":1,"score":0.37351715564727783},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.36540648341178894},{"id":"https://openalex.org/C2776541429","wikidata":"https://www.wikidata.org/wiki/Q165328","display_name":"Osteoporosis","level":2,"score":0.34120339155197144},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.3263821601867676},{"id":"https://openalex.org/C3018268312","wikidata":"https://www.wikidata.org/wiki/Q2671642","display_name":"Trabecular bone","level":3,"score":0.2978537678718567},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.276424378156662},{"id":"https://openalex.org/C202751555","wikidata":"https://www.wikidata.org/wiki/Q221681","display_name":"In vitro","level":2,"score":0.08527210354804993},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001846","descriptor_name":"Bone Development","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D001861","descriptor_name":"Bone Regeneration","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004285","descriptor_name":"Dogs","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005269","descriptor_name":"Femur","qualifier_ui":"Q000293","qualifier_name":"injuries","is_major_topic":false},{"descriptor_ui":"D008159","descriptor_name":"Lumbar Vertebrae","qualifier_ui":"Q000033","qualifier_name":"anatomy & histology","is_major_topic":true},{"descriptor_ui":"D008159","descriptor_name":"Lumbar Vertebrae","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D011458","descriptor_name":"Prostaglandins E","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":false},{"descriptor_ui":"D011458","descriptor_name":"Prostaglandins E","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D012272","descriptor_name":"Ribs","qualifier_ui":"Q000293","qualifier_name":"injuries","is_major_topic":false},{"descriptor_ui":"D013977","descriptor_name":"Tibia","qualifier_ui":"Q000293","qualifier_name":"injuries","is_major_topic":false},{"descriptor_ui":"D014945","descriptor_name":"Wound Healing","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015232","descriptor_name":"Dinoprostone","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D050723","descriptor_name":"Fractures, Bone","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1007/bf02556354","doi":"https://doi.org/10.1007/bf02556354","is_oa":false,"landing_page_url":"https://doi.org/10.1007/bf02556354","pdf_url":null,"source":{"id":"https://openalex.org/S197748570","display_name":"Calcified Tissue International","issn_l":"0171-967X","issn":["0171-967X","1432-0827"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Calcified Tissue International","raw_type":"journal-article"},{"id":"pmid:3135105","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/3135105","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Calcified tissue international","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.9391000270843506}],"sustainable_development_goals_aurora":[{"id":"https://metadata.un.org/sdg/15","display_name":"Life on land","score":0.550000011920929}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":31,"referenced_works":["https://openalex.org/W1585377912","https://openalex.org/W1599265950","https://openalex.org/W1891376806","https://openalex.org/W1963655248","https://openalex.org/W1984631888","https://openalex.org/W2006847412","https://openalex.org/W2021451961","https://openalex.org/W2030539466","https://openalex.org/W2031981657","https://openalex.org/W2032009308","https://openalex.org/W2037184705","https://openalex.org/W2049440139","https://openalex.org/W2049787159","https://openalex.org/W2054487668","https://openalex.org/W2062355922","https://openalex.org/W2066318392","https://openalex.org/W2080925793","https://openalex.org/W2088442254","https://openalex.org/W2089121163","https://openalex.org/W2092594627","https://openalex.org/W2093224917","https://openalex.org/W2114611015","https://openalex.org/W2124765369","https://openalex.org/W2136603711","https://openalex.org/W2156101967","https://openalex.org/W2235296721","https://openalex.org/W2333710622","https://openalex.org/W2469532228","https://openalex.org/W2474003815","https://openalex.org/W2573198204","https://openalex.org/W4214749173"],"related_works":["https://openalex.org/W2093662953","https://openalex.org/W2006847412","https://openalex.org/W2404151015","https://openalex.org/W1599265950","https://openalex.org/W2031981657","https://openalex.org/W4407211706","https://openalex.org/W2061524125","https://openalex.org/W2093224917","https://openalex.org/W2085182763","https://openalex.org/W1997763265"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2019,"cited_by_count":2},{"year":2015,"cited_by_count":1},{"year":2012,"cited_by_count":3}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}