{"id":"https://openalex.org/W1968442479","doi":"https://doi.org/10.1021/bi049697h","title":"Structure of a Quinobenzoxazine\u2212G-Quadruplex Complex by REDOR NMR","display_name":"Structure of a Quinobenzoxazine\u2212G-Quadruplex Complex by REDOR NMR","publication_year":2004,"publication_date":"2004-08-28","ids":{"openalex":"https://openalex.org/W1968442479","doi":"https://doi.org/10.1021/bi049697h","mag":"1968442479","pmid":"https://pubmed.ncbi.nlm.nih.gov/15379535"},"language":"en","primary_location":{"id":"doi:10.1021/bi049697h","doi":"https://doi.org/10.1021/bi049697h","is_oa":false,"landing_page_url":"https://doi.org/10.1021/bi049697h","pdf_url":null,"source":{"id":"https://openalex.org/S104038378","display_name":"Biochemistry","issn_l":"0006-2960","issn":["0006-2960","1520-4995","1943-295X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320006","host_organization_name":"American Chemical Society","host_organization_lineage":["https://openalex.org/P4310320006"],"host_organization_lineage_names":["American Chemical Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biochemistry","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":null,"display_name":"Anil K. Mehta","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I138006243","display_name":"University of Arizona","ror":"https://ror.org/03m2x1q45","country_code":"US","type":"education","lineage":["https://openalex.org/I138006243"]},{"id":"https://openalex.org/I204465549","display_name":"Washington University in St. Louis","ror":"https://ror.org/01yc7t268","country_code":"US","type":"education","lineage":["https://openalex.org/I204465549"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Anil K. Mehta","raw_affiliation_strings":["Department of Chemistry, Washington University, St. Louis, Missouri 63130, and College of Pharmacy, University of Arizona, Tucson, Arizona 85721"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry, Washington University, St. Louis, Missouri 63130, and College of Pharmacy, University of Arizona, Tucson, Arizona 85721","institution_ids":["https://openalex.org/I138006243","https://openalex.org/I204465549"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5034223308","display_name":"Yuda Shayo","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I138006243","display_name":"University of Arizona","ror":"https://ror.org/03m2x1q45","country_code":"US","type":"education","lineage":["https://openalex.org/I138006243"]},{"id":"https://openalex.org/I204465549","display_name":"Washington University in St. Louis","ror":"https://ror.org/01yc7t268","country_code":"US","type":"education","lineage":["https://openalex.org/I204465549"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Yuda Shayo","raw_affiliation_strings":["Department of Chemistry, Washington University, St. Louis, Missouri 63130, and College of Pharmacy, University of Arizona, Tucson, Arizona 85721"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry, Washington University, St. Louis, Missouri 63130, and College of Pharmacy, University of Arizona, Tucson, Arizona 85721","institution_ids":["https://openalex.org/I138006243","https://openalex.org/I204465549"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5081486992","display_name":"Hariprasad Vankayalapati","orcid":"https://orcid.org/0000-0002-5477-2124","observed_orcids":["https://orcid.org/0000-0002-5477-2124"]},"institutions":[{"id":"https://openalex.org/I138006243","display_name":"University of Arizona","ror":"https://ror.org/03m2x1q45","country_code":"US","type":"education","lineage":["https://openalex.org/I138006243"]},{"id":"https://openalex.org/I204465549","display_name":"Washington University in St. Louis","ror":"https://ror.org/01yc7t268","country_code":"US","type":"education","lineage":["https://openalex.org/I204465549"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Hariprasad Vankayalapati","raw_affiliation_strings":["Department of Chemistry, Washington University, St. Louis, Missouri 63130, and College of Pharmacy, University of Arizona, Tucson, Arizona 85721"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry, Washington University, St. Louis, Missouri 63130, and College of Pharmacy, University of Arizona, Tucson, Arizona 85721","institution_ids":["https://openalex.org/I138006243","https://openalex.org/I204465549"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5061843423","display_name":"Laurence H. Hurley","orcid":"https://orcid.org/0000-0002-8522-450X","observed_orcids":["https://orcid.org/0000-0002-8522-450X"]},"institutions":[{"id":"https://openalex.org/I138006243","display_name":"University of Arizona","ror":"https://ror.org/03m2x1q45","country_code":"US","type":"education","lineage":["https://openalex.org/I138006243"]},{"id":"https://openalex.org/I204465549","display_name":"Washington University in St. Louis","ror":"https://ror.org/01yc7t268","country_code":"US","type":"education","lineage":["https://openalex.org/I204465549"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Laurence H. Hurley","raw_affiliation_strings":["Department of Chemistry, Washington University, St. Louis, Missouri 63130, and College of Pharmacy, University of Arizona, Tucson, Arizona 85721"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry, Washington University, St. Louis, Missouri 63130, and College of Pharmacy, University of Arizona, Tucson, Arizona 85721","institution_ids":["https://openalex.org/I138006243","https://openalex.org/I204465549"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5103146642","display_name":"Jacob Schaefer","orcid":"https://orcid.org/0000-0002-7544-6408","observed_orcids":["https://orcid.org/0000-0002-7544-6408","https://orcid.org/0009-0008-4979-9833"]},"institutions":[{"id":"https://openalex.org/I138006243","display_name":"University of Arizona","ror":"https://ror.org/03m2x1q45","country_code":"US","type":"education","lineage":["https://openalex.org/I138006243"]},{"id":"https://openalex.org/I204465549","display_name":"Washington University in St. Louis","ror":"https://ror.org/01yc7t268","country_code":"US","type":"education","lineage":["https://openalex.org/I204465549"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Jacob Schaefer","raw_affiliation_strings":["Department of Chemistry, Washington University, St. Louis, Missouri 63130, and College of Pharmacy, University of Arizona, Tucson, Arizona 85721"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry, Washington University, St. Louis, Missouri 63130, and College of Pharmacy, University of Arizona, Tucson, Arizona 85721","institution_ids":["https://openalex.org/I138006243","https://openalex.org/I204465549"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5103146642"],"corresponding_institution_ids":["https://openalex.org/I138006243","https://openalex.org/I204465549"],"apc_list":{"value":4500,"currency":"USD","value_usd":4500},"apc_paid":null,"fwci":1.0652,"has_fulltext":false,"cited_by_count":27,"citation_normalized_percentile":{"value":0.71970445,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":96},"biblio":{"volume":"43","issue":"38","first_page":"11953","last_page":"11958"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10432","display_name":"DNA and Nucleic Acid Chemistry","score":0.9980000257492065,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10432","display_name":"DNA and Nucleic Acid Chemistry","score":0.9980000257492065,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11809","display_name":"Advanced NMR Techniques and Applications","score":0.0005000000237487257,"subfield":{"id":"https://openalex.org/subfields/1607","display_name":"Spectroscopy"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10163","display_name":"Metal complexes synthesis and properties","score":0.0003000000142492354,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/g-quadruplex","display_name":"G-quadruplex","score":0.9580000042915344},{"id":"https://openalex.org/keywords/dna-binding","display_name":"DNA binding","score":0.6579999923706055},{"id":"https://openalex.org/keywords/redor","display_name":"REDOR","score":0.5910000205039978},{"id":"https://openalex.org/keywords/fluorinated-ligands","display_name":"fluorinated ligands","score":0.45899999141693115}],"concepts":[{"id":"https://openalex.org/C83762044","wikidata":"https://www.wikidata.org/wiki/Q411641","display_name":"G-quadruplex","level":3,"score":0.5158280730247498},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.5121921896934509},{"id":"https://openalex.org/C552990157","wikidata":"https://www.wikidata.org/wiki/Q7430","display_name":"DNA","level":2,"score":0.10907480120658875},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.10827428102493286}],"mesh":[{"descriptor_ui":"D001483","descriptor_name":"Base Sequence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004247","descriptor_name":"DNA","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D004247","descriptor_name":"DNA","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D006147","descriptor_name":"Guanine","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D008958","descriptor_name":"Models, Molecular","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009682","descriptor_name":"Magnetic Resonance Spectroscopy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009690","descriptor_name":"Nucleic Acid Conformation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010078","descriptor_name":"Oxazines","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D011804","descriptor_name":"Quinolines","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D015394","descriptor_name":"Molecular Structure","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D054856","descriptor_name":"G-Quadruplexes","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1021/bi049697h","doi":"https://doi.org/10.1021/bi049697h","is_oa":false,"landing_page_url":"https://doi.org/10.1021/bi049697h","pdf_url":null,"source":{"id":"https://openalex.org/S104038378","display_name":"Biochemistry","issn_l":"0006-2960","issn":["0006-2960","1520-4995","1943-295X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320006","host_organization_name":"American Chemical Society","host_organization_lineage":["https://openalex.org/P4310320006"],"host_organization_lineage_names":["American Chemical Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biochemistry","raw_type":"journal-article"},{"id":"pmid:15379535","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/15379535","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biochemistry","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G2284484778","display_name":"Protein Binding Sites by REDOR NMR","funder_award_id":"R01EB001964","funder_id":"https://openalex.org/F4320337363","funder_display_name":"National Institute of Biomedical Imaging and Bioengineering"},{"id":"https://openalex.org/G4315172137","display_name":null,"funder_award_id":"CA 49751","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"},{"id":"https://openalex.org/G5678937609","display_name":null,"funder_award_id":"EB01964","funder_id":"https://openalex.org/F4320337363","funder_display_name":"National Institute of Biomedical Imaging and Bioengineering"}],"funders":[{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337351","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81"},{"id":"https://openalex.org/F4320337363","display_name":"National Institute of Biomedical Imaging and Bioengineering","ror":"https://ror.org/00372qc85"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":8,"referenced_works":["https://openalex.org/W1989198416","https://openalex.org/W1996234569","https://openalex.org/W2021312533","https://openalex.org/W2046608743","https://openalex.org/W2049659009","https://openalex.org/W2055822960","https://openalex.org/W2078500717","https://openalex.org/W2087786864"],"related_works":["https://openalex.org/W2969950051","https://openalex.org/W2590516521","https://openalex.org/W2772992695","https://openalex.org/W1966306581","https://openalex.org/W2618682723","https://openalex.org/W7126276746","https://openalex.org/W2055847208","https://openalex.org/W7083630733","https://openalex.org/W7147584847","https://openalex.org/W2090085796"],"abstract_inverted_index":{"Rotational-echo":[0],"double":[1],"resonance":[2],"solid-state":[3],"(31)P[(19)F]":[4],"and":[5,26],"(13)C[(19)F]":[6],"NMR":[7],"spectra":[8],"have":[9],"been":[10],"used":[11],"to":[12,19],"locate":[13],"the":[14],"binding":[15],"of":[16],"a":[17,20],"fluoroquinobenzoxazine":[18],"DNA":[21],"G-quadruplex":[22],"labeled":[23],"by":[24],"phosphorothioation":[25],"[methyl-(13)C]thymidine.":[27]},"counts_by_year":[{"year":2024,"cited_by_count":1},{"year":2022,"cited_by_count":3},{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":1},{"year":2014,"cited_by_count":1},{"year":2013,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}