{"id":"https://openalex.org/W1968417803","doi":"https://doi.org/10.5631/jibirinsuppl.141.46","title":"Concurrent Superselective Intra-arterial Chemoradiotherapy for Advanced Squamous Cell Carcinomas of the Maxillary Sinus and Upper Gingiva Involving the Maxillary Sinus","display_name":"Concurrent Superselective Intra-arterial Chemoradiotherapy for Advanced Squamous Cell Carcinomas of the Maxillary Sinus and Upper Gingiva Involving the Maxillary Sinus","publication_year":2015,"publication_date":"2015-01-01","ids":{"openalex":"https://openalex.org/W1968417803","doi":"https://doi.org/10.5631/jibirinsuppl.141.46","mag":"1968417803"},"language":"en","primary_location":{"id":"doi:10.5631/jibirinsuppl.141.46","doi":"https://doi.org/10.5631/jibirinsuppl.141.46","is_oa":true,"landing_page_url":"https://doi.org/10.5631/jibirinsuppl.141.46","pdf_url":null,"source":{"id":"https://openalex.org/S4210188257","display_name":"Practica oto-rhino-laryngologica Suppl","issn_l":"0912-1870","issn":["0912-1870","2185-1557"],"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":["poland-20","russia-white-list-4"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Practica oto-rhino-laryngologica. Suppl.","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"diamond","oa_url":"https://doi.org/10.5631/jibirinsuppl.141.46","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5111721717","display_name":"Haruo Hirakawa","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210160686","display_name":"Kure Medical Center","ror":"https://ror.org/05te51965","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210137409","https://openalex.org/I4210160686"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Haruo Hirakawa","raw_affiliation_strings":["Department of Otolaryngology, Kure Medical Center and Chugoku Cancer Center"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Otolaryngology, Kure Medical Center and Chugoku Cancer Center","institution_ids":["https://openalex.org/I4210160686"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Yasuyuki Nishi","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210160686","display_name":"Kure Medical Center","ror":"https://ror.org/05te51965","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210137409","https://openalex.org/I4210160686"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Yasuyuki Nishi","raw_affiliation_strings":["Department of Otolaryngology, Kure Medical Center and Chugoku Cancer Center"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Otolaryngology, Kure Medical Center and Chugoku Cancer Center","institution_ids":["https://openalex.org/I4210160686"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101474654","display_name":"Makoto Tada","orcid":"https://orcid.org/0000-0002-5774-8795","observed_orcids":["https://orcid.org/0000-0002-5774-8795"]},"institutions":[{"id":"https://openalex.org/I4210160686","display_name":"Kure Medical Center","ror":"https://ror.org/05te51965","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210137409","https://openalex.org/I4210160686"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Makoto Tada","raw_affiliation_strings":["Department of Otolaryngology, Kure Medical Center and Chugoku Cancer Center"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Otolaryngology, Kure Medical Center and Chugoku Cancer Center","institution_ids":["https://openalex.org/I4210160686"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5003163678","display_name":"Taisuke Watanabe","orcid":"https://orcid.org/0000-0003-1281-7117","observed_orcids":["https://orcid.org/0000-0003-1281-7117"]},"institutions":[{"id":"https://openalex.org/I4210160686","display_name":"Kure Medical Center","ror":"https://ror.org/05te51965","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210137409","https://openalex.org/I4210160686"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Taisuke Watanabe","raw_affiliation_strings":["Department of Otolaryngology, Kure Medical Center and Chugoku Cancer Center"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Otolaryngology, Kure Medical Center and Chugoku Cancer Center","institution_ids":["https://openalex.org/I4210160686"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I4210160686"],"apc_list":null,"apc_paid":null,"fwci":0.618,"has_fulltext":false,"cited_by_count":2,"citation_normalized_percentile":{"value":0.67346505,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":93},"biblio":{"volume":"141","issue":"0","first_page":"46","last_page":"47"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10307","display_name":"Head and Neck Cancer Studies","score":0.7461000084877014,"subfield":{"id":"https://openalex.org/subfields/2733","display_name":"Otorhinolaryngology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10307","display_name":"Head and Neck Cancer Studies","score":0.7461000084877014,"subfield":{"id":"https://openalex.org/subfields/2733","display_name":"Otorhinolaryngology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11669","display_name":"Head and Neck Surgical Oncology","score":0.24770000576972961,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11176","display_name":"Radiation Therapy and Dosimetry","score":0.000699999975040555,"subfield":{"id":"https://openalex.org/subfields/3108","display_name":"Radiation"},"field":{"id":"https://openalex.org/fields/31","display_name":"Physics and Astronomy"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/squamous-cell-carcinoma","display_name":"squamous cell carcinoma","score":0.8790000081062317},{"id":"https://openalex.org/keywords/maxillary-sinus-carcinoma","display_name":"maxillary sinus cancer","score":0.8299999833106995},{"id":"https://openalex.org/keywords/cisplatin","display_name":"cisplatin","score":0.8389999866485596},{"id":"https://openalex.org/keywords/sodium-thiosulfate","display_name":"sodium thiosulfate","score":0.9279999732971191},{"id":"https://openalex.org/keywords/5-fluorouracil","display_name":"5-fluorouracil","score":0.9789999723434448},{"id":"https://openalex.org/keywords/head-and-neck-cancer","display_name":"head and neck cancer","score":0.8169999718666077},{"id":"https://openalex.org/keywords/concurrent-chemoradiotherapy","display_name":"concurrent chemoradiotherapy","score":0.7480000257492065},{"id":"https://openalex.org/keywords/microcatheter","display_name":"microcatheter","score":0.5519999861717224},{"id":"https://openalex.org/keywords/lymph-node-metastasis","display_name":"lymph node metastasis","score":0.5789999961853027}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9025372266769409},{"id":"https://openalex.org/C2778705571","wikidata":"https://www.wikidata.org/wiki/Q6498170","display_name":"Maxillary sinus","level":2,"score":0.6067781448364258},{"id":"https://openalex.org/C2778239845","wikidata":"https://www.wikidata.org/wiki/Q412415","display_name":"Cisplatin","level":3,"score":0.5720838904380798},{"id":"https://openalex.org/C2778424827","wikidata":"https://www.wikidata.org/wiki/Q5090613","display_name":"Chemoradiotherapy","level":3,"score":0.5464441180229187},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.49255213141441345},{"id":"https://openalex.org/C2781267111","wikidata":"https://www.wikidata.org/wiki/Q652297","display_name":"Catheter","level":2,"score":0.4752002954483032},{"id":"https://openalex.org/C509974204","wikidata":"https://www.wikidata.org/wiki/Q180507","display_name":"Radiation therapy","level":2,"score":0.4731025695800781},{"id":"https://openalex.org/C2776530083","wikidata":"https://www.wikidata.org/wiki/Q1783924","display_name":"Head and neck cancer","level":3,"score":0.43060746788978577},{"id":"https://openalex.org/C2776694085","wikidata":"https://www.wikidata.org/wiki/Q974135","display_name":"Chemotherapy","level":2,"score":0.4193676710128784},{"id":"https://openalex.org/C126894567","wikidata":"https://www.wikidata.org/wiki/Q105650","display_name":"Urology","level":1,"score":0.3578769266605377}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.5631/jibirinsuppl.141.46","doi":"https://doi.org/10.5631/jibirinsuppl.141.46","is_oa":true,"landing_page_url":"https://doi.org/10.5631/jibirinsuppl.141.46","pdf_url":null,"source":{"id":"https://openalex.org/S4210188257","display_name":"Practica oto-rhino-laryngologica Suppl","issn_l":"0912-1870","issn":["0912-1870","2185-1557"],"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":["poland-20","russia-white-list-4"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Practica oto-rhino-laryngologica. Suppl.","raw_type":"journal-article"}],"best_oa_location":{"id":"doi:10.5631/jibirinsuppl.141.46","doi":"https://doi.org/10.5631/jibirinsuppl.141.46","is_oa":true,"landing_page_url":"https://doi.org/10.5631/jibirinsuppl.141.46","pdf_url":null,"source":{"id":"https://openalex.org/S4210188257","display_name":"Practica oto-rhino-laryngologica Suppl","issn_l":"0912-1870","issn":["0912-1870","2185-1557"],"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":["poland-20","russia-white-list-4"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Practica oto-rhino-laryngologica. Suppl.","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":1.0}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":8,"referenced_works":["https://openalex.org/W1984389010","https://openalex.org/W1997893991","https://openalex.org/W2021793507","https://openalex.org/W2043969654","https://openalex.org/W2096550186","https://openalex.org/W2133040473","https://openalex.org/W2314031747","https://openalex.org/W2328376985"],"related_works":["https://openalex.org/W2589789011","https://openalex.org/W2004866560","https://openalex.org/W2325891686","https://openalex.org/W2080879941","https://openalex.org/W7154082794","https://openalex.org/W2082488319","https://openalex.org/W4225268918","https://openalex.org/W2126015451","https://openalex.org/W2018096034","https://openalex.org/W2048175767"],"abstract_inverted_index":{"Concurrent":[0],"superselective":[1,11],"intra-arterial":[2,12,78],"chemoradiotherapy":[3,8],"(SIACRT),":[4],"a":[5,16,83,105,129],"combination":[6],"of":[7,26,38,73,86,107,126,136,149,172,210,226,234,243,250],"(CRT)":[9],"and":[10,29,42,47,63,67,158,187,194,228],"chemotherapy":[13],"(SIAC),":[14],"is":[15],"new":[17],"therapeutic":[18],"strategy":[19],"for":[20,36,198],"advanced":[21],"squamous":[22],"cell":[23],"carcinomas":[24],"(SCCs)":[25],"the":[27,39,50,87,98,102,113,124,134,137,143,154,163,182,206,211,223,230,244,248],"head":[28],"neck.":[30],"We":[31],"have":[32],"been":[33],"applying":[34],"SIACRT":[35,55,238,251],"SCC":[37],"maxillary":[40],"sinus":[41],"upper":[43],"gingiva":[44],"since":[45],"2008":[46],"present":[48],"herein":[49],"outcomes":[51],"at":[52,104,122],"our":[53],"hospital.":[54],"was":[56,80,95,119,140,152,174,184],"applied":[57,185],"in":[58,128,162,214,229],"10":[59],"cases":[60],"between":[61],"2009":[62],"2012,":[64],"7":[65],"males":[66],"3":[68],"females":[69],"with":[70],"an":[71],"age-range":[72],"57":[74],"to":[75,132,176],"81.":[76],"An":[77],"micro-catheter":[79],"inserted":[81],"into":[82,97],"feeding":[84],"artery":[85],"tumor":[88,99],"super-selectively":[89],"using":[90],"Seldinger\u2019s":[91],"method.":[92],"Cisplatin":[93],"(CDDP)":[94],"injected":[96],"intra-arterially":[100],"through":[101],"catheter":[103],"rate":[106],"5":[108],"mg":[109],"per":[110],"minute.":[111],"At":[112],"same":[114,144,164],"time":[115],"sodium":[116],"thiosulfate":[117],"(STS)":[118],"intravenously":[120],"administered":[121,161],"200-fold":[123],"dose":[125,171],"CDDP":[127,157],"molar":[130],"quantity":[131],"reduce":[133],"toxicity":[135],"CDDP.":[138],"Irradiation":[139],"started":[141,153],"on":[142],"day.":[145,156],"Five-day-continuous":[146],"intravenous":[147],"administration":[148,225],"5-fluorouracil":[150],"(5FU)":[151],"next":[155],"5FU":[159],"were":[160,239],"way":[165],"four":[166],"weeks":[167],"later.":[168],"The":[169],"total":[170],"irradiation":[173],"50":[175],"60":[177],"Gy.":[178],"In":[179,203,241],"eight":[180,245],"cases,":[181,205,220,247],"protocol":[183],"correctly,":[186],"these":[188,219],"patients":[189],"showed":[190],"complete":[191],"response":[192,216],"(CR)":[193],"survived":[195],"without":[196],"disease":[197],"more":[199],"than":[200],"15":[201],"months.":[202],"two":[204,232,242],"patient":[207],"dropped":[208],"out":[209],"protocol,":[212],"resulting":[213],"partial":[215],"(PR).":[217],"Of":[218],"one":[221],"refused":[222],"2nd":[224],"SIAC":[227,235],"other":[231],"courses":[233],"followed":[236],"by":[237],"administered.":[240],"CR":[246],"application":[249],"eliminated":[252],"metastatic":[253],"lymph":[254],"node":[255],"tumors.":[256]},"counts_by_year":[{"year":2016,"cited_by_count":1},{"year":2015,"cited_by_count":1}],"updated_date":"2026-09-29T14:09:16.559479","created_date":"2016-06-24T00:00:00"}