{"id":"https://openalex.org/W1968396325","doi":"https://doi.org/10.1164/rccm.200502-210oc","title":"Inhaled Corticosteroids in Chronic Obstructive Pulmonary Disease","display_name":"Inhaled Corticosteroids in Chronic Obstructive Pulmonary Disease","publication_year":2005,"publication_date":"2005-05-18","ids":{"openalex":"https://openalex.org/W1968396325","doi":"https://doi.org/10.1164/rccm.200502-210oc","mag":"1968396325","pmid":"https://pubmed.ncbi.nlm.nih.gov/15901610"},"language":"en","primary_location":{"id":"doi:10.1164/rccm.200502-210oc","doi":"https://doi.org/10.1164/rccm.200502-210oc","is_oa":false,"landing_page_url":"https://doi.org/10.1164/rccm.200502-210oc","pdf_url":null,"source":{"id":"https://openalex.org/S93356601","display_name":"American Journal of Respiratory and Critical Care Medicine","issn_l":"1073-449X","issn":["1073-449X","1535-4970"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310316311","host_organization_name":"American Thoracic Society","host_organization_lineage":["https://openalex.org/P4310316311"],"host_organization_lineage_names":["American Thoracic Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"American Journal of Respiratory and Critical Care Medicine","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5112088262","display_name":"Victor Alangibi Kiri","orcid":"https://orcid.org/0000-0001-7171-2011","observed_orcids":["https://orcid.org/0000-0001-7171-2011"]},"institutions":[{"id":"https://openalex.org/I188950975","display_name":"GlaxoSmithKline (United Kingdom)","ror":"https://ror.org/01xsqw823","country_code":"GB","type":"company","lineage":["https://openalex.org/I188950975"]},{"id":"https://openalex.org/I2801942218","display_name":"Hvidovre Hospital","ror":"https://ror.org/00edrn755","country_code":"DK","type":"healthcare","lineage":["https://openalex.org/I2801942218","https://openalex.org/I2802567020"]},{"id":"https://openalex.org/I28407311","display_name":"University of Manchester","ror":"https://ror.org/027m9bs27","country_code":"GB","type":"education","lineage":["https://openalex.org/I28407311"]},{"id":"https://openalex.org/I4210089966","display_name":"London School of Hygiene & Tropical Medicine","ror":"https://ror.org/00a0jsq62","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I4210089966"]},{"id":"https://openalex.org/I47508984","display_name":"Imperial College London","ror":"https://ror.org/041kmwe10","country_code":"GB","type":"education","lineage":["https://openalex.org/I47508984"]},{"id":"https://openalex.org/I79576946","display_name":"University of Pennsylvania","ror":"https://ror.org/00b30xv10","country_code":"US","type":"education","lineage":["https://openalex.org/I79576946"]}],"countries":["DK","GB","US"],"is_corresponding":false,"raw_author_name":"Victor A. Kiri","raw_affiliation_strings":["Worldwide Epidemiology, GlaxoSmithKline, Greenford; National Centre for Health Outcomes Development, and Department of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine; Thoracic Medicine, National Heart and Lung Institute, Imperial College, London; North West Lung Centre, South Manchester University Hospital Trust, Manchester, United Kingdom; Worldwide Epidemiology, GlaxoSmithKline, Upper Providence; Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania; and Department of Heart and Lung Diseases, Hvidovre Hospital, Hvidovre, Denmark","Worldwide Epidemiology, GlaxoSmithKline, Greenford; National Centre for Health Outcomes Development, and Department of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine; Thoracic Medicine, National Heart and Lung Institute, Imperial College, London; North West Lung Centre, South Manchester University Hospital Trust, Manchester, United Kingdom; Worldwide Epidemiology, GlaxoSmithKline, Upper Providence; Center for Clinical Epidemiology and Biostatistics, University of"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Worldwide Epidemiology, GlaxoSmithKline, Greenford; National Centre for Health Outcomes Development, and Department of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine; Thoracic Medicine, National Heart and Lung Institute, Imperial College, London; North West Lung Centre, South Manchester University Hospital Trust, Manchester, United Kingdom; Worldwide Epidemiology, GlaxoSmithKline, Upper Providence; Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania; and Department of Heart and Lung Diseases, Hvidovre Hospital, Hvidovre, Denmark","institution_ids":["https://openalex.org/I188950975","https://openalex.org/I2801942218","https://openalex.org/I4210089966","https://openalex.org/I47508984","https://openalex.org/I79576946"]},{"raw_affiliation_string":"Worldwide Epidemiology, GlaxoSmithKline, Greenford; National Centre for Health Outcomes Development, and Department of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine; Thoracic Medicine, National Heart and Lung Institute, Imperial College, London; North West Lung Centre, South Manchester University Hospital Trust, Manchester, United Kingdom; Worldwide Epidemiology, GlaxoSmithKline, Upper Providence; Center for Clinical Epidemiology and Biostatistics, University of","institution_ids":["https://openalex.org/I188950975","https://openalex.org/I28407311","https://openalex.org/I4210089966","https://openalex.org/I47508984"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109874172","display_name":"Neil B. Pride","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I188950975","display_name":"GlaxoSmithKline (United Kingdom)","ror":"https://ror.org/01xsqw823","country_code":"GB","type":"company","lineage":["https://openalex.org/I188950975"]},{"id":"https://openalex.org/I2801942218","display_name":"Hvidovre Hospital","ror":"https://ror.org/00edrn755","country_code":"DK","type":"healthcare","lineage":["https://openalex.org/I2801942218","https://openalex.org/I2802567020"]},{"id":"https://openalex.org/I28407311","display_name":"University of Manchester","ror":"https://ror.org/027m9bs27","country_code":"GB","type":"education","lineage":["https://openalex.org/I28407311"]},{"id":"https://openalex.org/I4210089966","display_name":"London School of Hygiene & Tropical Medicine","ror":"https://ror.org/00a0jsq62","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I4210089966"]},{"id":"https://openalex.org/I47508984","display_name":"Imperial College London","ror":"https://ror.org/041kmwe10","country_code":"GB","type":"education","lineage":["https://openalex.org/I47508984"]},{"id":"https://openalex.org/I79576946","display_name":"University of Pennsylvania","ror":"https://ror.org/00b30xv10","country_code":"US","type":"education","lineage":["https://openalex.org/I79576946"]}],"countries":["DK","GB","US"],"is_corresponding":false,"raw_author_name":"Neil B. Pride","raw_affiliation_strings":["Worldwide Epidemiology, GlaxoSmithKline, Greenford; National Centre for Health Outcomes Development, and Department of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine; Thoracic Medicine, National Heart and Lung Institute, Imperial College, London; North West Lung Centre, South Manchester University Hospital Trust, Manchester, United Kingdom; Worldwide Epidemiology, GlaxoSmithKline, Upper Providence; Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania; and Department of Heart and Lung Diseases, Hvidovre Hospital, Hvidovre, Denmark","Worldwide Epidemiology, GlaxoSmithKline, Greenford; National Centre for Health Outcomes Development, and Department of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine; Thoracic Medicine, National Heart and Lung Institute, Imperial College, London; North West Lung Centre, South Manchester University Hospital Trust, Manchester, United Kingdom; Worldwide Epidemiology, GlaxoSmithKline, Upper Providence; Center for Clinical Epidemiology and Biostatistics, University of"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Worldwide Epidemiology, GlaxoSmithKline, Greenford; National Centre for Health Outcomes Development, and Department of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine; Thoracic Medicine, National Heart and Lung Institute, Imperial College, London; North West Lung Centre, South Manchester University Hospital Trust, Manchester, United Kingdom; Worldwide Epidemiology, GlaxoSmithKline, Upper Providence; Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania; and Department of Heart and Lung Diseases, Hvidovre Hospital, Hvidovre, Denmark","institution_ids":["https://openalex.org/I188950975","https://openalex.org/I2801942218","https://openalex.org/I4210089966","https://openalex.org/I47508984","https://openalex.org/I79576946"]},{"raw_affiliation_string":"Worldwide Epidemiology, GlaxoSmithKline, Greenford; National Centre for Health Outcomes Development, and Department of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine; Thoracic Medicine, National Heart and Lung Institute, Imperial College, London; North West Lung Centre, South Manchester University Hospital Trust, Manchester, United Kingdom; Worldwide Epidemiology, GlaxoSmithKline, Upper Providence; Center for Clinical Epidemiology and Biostatistics, University of","institution_ids":["https://openalex.org/I188950975","https://openalex.org/I28407311","https://openalex.org/I4210089966","https://openalex.org/I47508984"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5059978160","display_name":"Joan Bautista Soriano","orcid":"https://orcid.org/0000-0001-9740-2994","observed_orcids":["https://orcid.org/0000-0001-9740-2994"]},"institutions":[{"id":"https://openalex.org/I188950975","display_name":"GlaxoSmithKline (United Kingdom)","ror":"https://ror.org/01xsqw823","country_code":"GB","type":"company","lineage":["https://openalex.org/I188950975"]},{"id":"https://openalex.org/I2801942218","display_name":"Hvidovre Hospital","ror":"https://ror.org/00edrn755","country_code":"DK","type":"healthcare","lineage":["https://openalex.org/I2801942218","https://openalex.org/I2802567020"]},{"id":"https://openalex.org/I28407311","display_name":"University of Manchester","ror":"https://ror.org/027m9bs27","country_code":"GB","type":"education","lineage":["https://openalex.org/I28407311"]},{"id":"https://openalex.org/I4210089966","display_name":"London School of Hygiene & Tropical Medicine","ror":"https://ror.org/00a0jsq62","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I4210089966"]},{"id":"https://openalex.org/I47508984","display_name":"Imperial College London","ror":"https://ror.org/041kmwe10","country_code":"GB","type":"education","lineage":["https://openalex.org/I47508984"]},{"id":"https://openalex.org/I79576946","display_name":"University of Pennsylvania","ror":"https://ror.org/00b30xv10","country_code":"US","type":"education","lineage":["https://openalex.org/I79576946"]}],"countries":["DK","GB","US"],"is_corresponding":false,"raw_author_name":"Joan B. Soriano","raw_affiliation_strings":["Worldwide Epidemiology, GlaxoSmithKline, Greenford; National Centre for Health Outcomes Development, and Department of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine; Thoracic Medicine, National Heart and Lung Institute, Imperial College, London; North West Lung Centre, South Manchester University Hospital Trust, Manchester, United Kingdom; Worldwide Epidemiology, GlaxoSmithKline, Upper Providence; Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania; and Department of Heart and Lung Diseases, Hvidovre Hospital, Hvidovre, Denmark","Worldwide Epidemiology, GlaxoSmithKline, Greenford; National Centre for Health Outcomes Development, and Department of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine; Thoracic Medicine, National Heart and Lung Institute, Imperial College, London; North West Lung Centre, South Manchester University Hospital Trust, Manchester, United Kingdom; Worldwide Epidemiology, GlaxoSmithKline, Upper Providence; Center for Clinical Epidemiology and Biostatistics, University of"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Worldwide Epidemiology, GlaxoSmithKline, Greenford; National Centre for Health Outcomes Development, and Department of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine; Thoracic Medicine, National Heart and Lung Institute, Imperial College, London; North West Lung Centre, South Manchester University Hospital Trust, Manchester, United Kingdom; Worldwide Epidemiology, GlaxoSmithKline, Upper Providence; Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania; and Department of Heart and Lung Diseases, Hvidovre Hospital, Hvidovre, Denmark","institution_ids":["https://openalex.org/I188950975","https://openalex.org/I2801942218","https://openalex.org/I4210089966","https://openalex.org/I47508984","https://openalex.org/I79576946"]},{"raw_affiliation_string":"Worldwide Epidemiology, GlaxoSmithKline, Greenford; National Centre for Health Outcomes Development, and Department of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine; Thoracic Medicine, National Heart and Lung Institute, Imperial College, London; North West Lung Centre, South Manchester University Hospital Trust, Manchester, United Kingdom; Worldwide Epidemiology, GlaxoSmithKline, Upper Providence; Center for Clinical Epidemiology and Biostatistics, University of","institution_ids":["https://openalex.org/I188950975","https://openalex.org/I28407311","https://openalex.org/I4210089966","https://openalex.org/I47508984"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5083312029","display_name":"J\u00f8rgen Vestbo","orcid":"https://orcid.org/0000-0001-6355-6362","observed_orcids":["https://orcid.org/0000-0001-6355-6362"]},"institutions":[{"id":"https://openalex.org/I188950975","display_name":"GlaxoSmithKline (United Kingdom)","ror":"https://ror.org/01xsqw823","country_code":"GB","type":"company","lineage":["https://openalex.org/I188950975"]},{"id":"https://openalex.org/I2801942218","display_name":"Hvidovre Hospital","ror":"https://ror.org/00edrn755","country_code":"DK","type":"healthcare","lineage":["https://openalex.org/I2801942218","https://openalex.org/I2802567020"]},{"id":"https://openalex.org/I28407311","display_name":"University of Manchester","ror":"https://ror.org/027m9bs27","country_code":"GB","type":"education","lineage":["https://openalex.org/I28407311"]},{"id":"https://openalex.org/I4210089966","display_name":"London School of Hygiene & Tropical Medicine","ror":"https://ror.org/00a0jsq62","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I4210089966"]},{"id":"https://openalex.org/I47508984","display_name":"Imperial College London","ror":"https://ror.org/041kmwe10","country_code":"GB","type":"education","lineage":["https://openalex.org/I47508984"]},{"id":"https://openalex.org/I79576946","display_name":"University of Pennsylvania","ror":"https://ror.org/00b30xv10","country_code":"US","type":"education","lineage":["https://openalex.org/I79576946"]}],"countries":["DK","GB","US"],"is_corresponding":false,"raw_author_name":"J\u00f8rgen Vestbo","raw_affiliation_strings":["Worldwide Epidemiology, GlaxoSmithKline, Greenford; National Centre for Health Outcomes Development, and Department of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine; Thoracic Medicine, National Heart and Lung Institute, Imperial College, London; North West Lung Centre, South Manchester University Hospital Trust, Manchester, United Kingdom; Worldwide Epidemiology, GlaxoSmithKline, Upper Providence; Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania; and Department of Heart and Lung Diseases, Hvidovre Hospital, Hvidovre, Denmark","Worldwide Epidemiology, GlaxoSmithKline, Greenford; National Centre for Health Outcomes Development, and Department of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine; Thoracic Medicine, National Heart and Lung Institute, Imperial College, London; North West Lung Centre, South Manchester University Hospital Trust, Manchester, United Kingdom; Worldwide Epidemiology, GlaxoSmithKline, Upper Providence; Center for Clinical Epidemiology and Biostatistics, University of"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Worldwide Epidemiology, GlaxoSmithKline, Greenford; National Centre for Health Outcomes Development, and Department of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine; Thoracic Medicine, National Heart and Lung Institute, Imperial College, London; North West Lung Centre, South Manchester University Hospital Trust, Manchester, United Kingdom; Worldwide Epidemiology, GlaxoSmithKline, Upper Providence; Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania; and Department of Heart and Lung Diseases, Hvidovre Hospital, Hvidovre, Denmark","institution_ids":["https://openalex.org/I188950975","https://openalex.org/I2801942218","https://openalex.org/I4210089966","https://openalex.org/I47508984","https://openalex.org/I79576946"]},{"raw_affiliation_string":"Worldwide Epidemiology, GlaxoSmithKline, Greenford; National Centre for Health Outcomes Development, and Department of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine; Thoracic Medicine, National Heart and Lung Institute, Imperial College, London; North West Lung Centre, South Manchester University Hospital Trust, Manchester, United Kingdom; Worldwide Epidemiology, GlaxoSmithKline, Upper Providence; Center for Clinical Epidemiology and Biostatistics, University of","institution_ids":["https://openalex.org/I188950975","https://openalex.org/I28407311","https://openalex.org/I4210089966","https://openalex.org/I47508984"]}]}],"institutions":[],"countries_distinct_count":3,"institutions_distinct_count":6,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":9.1753,"has_fulltext":false,"cited_by_count":90,"citation_normalized_percentile":{"value":0.98109565,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":87,"max":97},"biblio":{"volume":"172","issue":"4","first_page":"460","last_page":"464"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10143","display_name":"Chronic Obstructive Pulmonary Disease (COPD) Research","score":0.9955999851226807,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10143","display_name":"Chronic Obstructive Pulmonary Disease (COPD) Research","score":0.9955999851226807,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T14374","display_name":"Statistical Methods in Epidemiology","score":0.003100000089034438,"subfield":{"id":"https://openalex.org/subfields/2613","display_name":"Statistics and Probability"},"field":{"id":"https://openalex.org/fields/26","display_name":"Mathematics"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10051","display_name":"Asthma and respiratory diseases","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/inhaled-corticosteroids","display_name":"inhaled corticosteroids","score":0.9990000128746033},{"id":"https://openalex.org/keywords/chronic-obstructive-pulmonary-disease","display_name":"chronic obstructive pulmonary disease","score":1.0},{"id":"https://openalex.org/keywords/immortal-time-bias","display_name":"immortal time bias","score":0.9959999918937683},{"id":"https://openalex.org/keywords/mortality","display_name":"mortality","score":0.7770000100135803},{"id":"https://openalex.org/keywords/hospital-readmission","display_name":"hospital readmission","score":0.8730000257492065},{"id":"https://openalex.org/keywords/propensity-score-matching","display_name":"propensity score matching","score":0.8799999952316284},{"id":"https://openalex.org/keywords/nested-case-control-study","display_name":"nested case-control study","score":0.8999999761581421},{"id":"https://openalex.org/keywords/observational-study-validity","display_name":"observational study validity","score":0.6620000004768372}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9107060432434082},{"id":"https://openalex.org/C207103383","wikidata":"https://www.wikidata.org/wiki/Q3930246","display_name":"Hazard ratio","level":3,"score":0.8516256809234619},{"id":"https://openalex.org/C2776780178","wikidata":"https://www.wikidata.org/wiki/Q199804","display_name":"COPD","level":2,"score":0.8281842470169067},{"id":"https://openalex.org/C201903717","wikidata":"https://www.wikidata.org/wiki/Q1778788","display_name":"Cohort study","level":2,"score":0.6625246405601501},{"id":"https://openalex.org/C72563966","wikidata":"https://www.wikidata.org/wiki/Q1303415","display_name":"Cohort","level":2,"score":0.6529738903045654},{"id":"https://openalex.org/C44249647","wikidata":"https://www.wikidata.org/wiki/Q208498","display_name":"Confidence interval","level":2,"score":0.6486532688140869},{"id":"https://openalex.org/C17923572","wikidata":"https://www.wikidata.org/wiki/Q7250160","display_name":"Propensity score matching","level":2,"score":0.6104604601860046},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.5224199295043945},{"id":"https://openalex.org/C50382708","wikidata":"https://www.wikidata.org/wiki/Q223218","display_name":"Proportional hazards model","level":2,"score":0.46442878246307373},{"id":"https://openalex.org/C82789193","wikidata":"https://www.wikidata.org/wiki/Q2142611","display_name":"Relative risk","level":3,"score":0.41466620564460754},{"id":"https://openalex.org/C23131810","wikidata":"https://www.wikidata.org/wiki/Q818574","display_name":"Observational study","level":2,"score":0.4109213352203369}],"mesh":[{"descriptor_ui":"D000280","descriptor_name":"Administration, Inhalation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000893","descriptor_name":"Anti-Inflammatory Agents","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005938","descriptor_name":"Glucocorticoids","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":true},{"descriptor_ui":"D006760","descriptor_name":"Hospitalization","qualifier_ui":"Q000706","qualifier_name":"statistics & numerical data","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012107","descriptor_name":"Research Design","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012306","descriptor_name":"Risk","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013997","descriptor_name":"Time Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015331","descriptor_name":"Cohort Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015982","descriptor_name":"Bias","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016019","descriptor_name":"Survival Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016022","descriptor_name":"Case-Control Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016208","descriptor_name":"Databases, Factual","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D029424","descriptor_name":"Pulmonary Disease, Chronic Obstructive","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D029424","descriptor_name":"Pulmonary Disease, Chronic Obstructive","qualifier_ui":"Q000401","qualifier_name":"mortality","is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1164/rccm.200502-210oc","doi":"https://doi.org/10.1164/rccm.200502-210oc","is_oa":false,"landing_page_url":"https://doi.org/10.1164/rccm.200502-210oc","pdf_url":null,"source":{"id":"https://openalex.org/S93356601","display_name":"American Journal of Respiratory and Critical Care Medicine","issn_l":"1073-449X","issn":["1073-449X","1535-4970"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310316311","host_organization_name":"American Thoracic Society","host_organization_lineage":["https://openalex.org/P4310316311"],"host_organization_lineage_names":["American Thoracic Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"American Journal of Respiratory and Critical Care Medicine","raw_type":"journal-article"},{"id":"pmid:15901610","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/15901610","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"American journal of respiratory and critical care medicine","raw_type":"Journal Article"},{"id":"pmh:oai:pure.atira.dk:openaire_cris_publications/1622f4de-f4de-403b-97b1-8e681f5e4936","doi":null,"is_oa":false,"landing_page_url":"https://research.manchester.ac.uk/en/publications/1622f4de-f4de-403b-97b1-8e681f5e4936","pdf_url":null,"source":{"id":"https://openalex.org/S4306400662","display_name":"Research Explorer (The University of Manchester)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I28407311","host_organization_name":"University of Manchester","host_organization_lineage":["https://openalex.org/I28407311"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Kiri, V A, Pride, N B, Soriano, J B & Vestbo, J 2005, 'Inhaled corticosteroids in chronic obstructive pulmonary disease: Results from two observational designs free of immortal time bias', American Journal of Respiratory and Critical Care Medicine, vol. 172, no. 4, pp. 460-464. https://doi.org/10.1164/rccm.200502-210OC","raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.9940000176429749,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":40,"referenced_works":["https://openalex.org/W105318348","https://openalex.org/W131453520","https://openalex.org/W176029630","https://openalex.org/W629613351","https://openalex.org/W1557319476","https://openalex.org/W1691887444","https://openalex.org/W1692839365","https://openalex.org/W1799163667","https://openalex.org/W1939311003","https://openalex.org/W1967167093","https://openalex.org/W1972016629","https://openalex.org/W1987385040","https://openalex.org/W1998078123","https://openalex.org/W2041194326","https://openalex.org/W2045616259","https://openalex.org/W2051161384","https://openalex.org/W2066765285","https://openalex.org/W2071653242","https://openalex.org/W2092369059","https://openalex.org/W2109921129","https://openalex.org/W2120629366","https://openalex.org/W2121690051","https://openalex.org/W2125266996","https://openalex.org/W2129168200","https://openalex.org/W2133119676","https://openalex.org/W2133443469","https://openalex.org/W2136883754","https://openalex.org/W2141570612","https://openalex.org/W2151606278","https://openalex.org/W2152287842","https://openalex.org/W2157604999","https://openalex.org/W2159767143","https://openalex.org/W2166432084","https://openalex.org/W2166675610","https://openalex.org/W2169729194","https://openalex.org/W2186928376","https://openalex.org/W2268275976","https://openalex.org/W2315171876","https://openalex.org/W2416982860","https://openalex.org/W2463418118"],"related_works":["https://openalex.org/W1996990269","https://openalex.org/W2151606278","https://openalex.org/W1692839365","https://openalex.org/W4393330187","https://openalex.org/W1799163667","https://openalex.org/W4400053525","https://openalex.org/W2133545510","https://openalex.org/W2146248083","https://openalex.org/W4249108522","https://openalex.org/W2109921129"],"abstract_inverted_index":{"RATIONALE:":[0],"Recent":[1],"cohort":[2,116,138,159,175],"studies":[3,39],"in":[4,24,28,60,83,89,135,230,256],"chronic":[5],"obstructive":[6],"pulmonary":[7],"disease":[8],"(COPD)":[9],"have":[10,40],"questioned":[11],"the":[12,48,55,84,90,107,125,136,158,231,249],"validity":[13],"of":[14,34,57,63,78,110,177,192,206,218],"previously":[15],"reported":[16],"associations":[17],"between":[18],"inhaled":[19],"corticosteroids":[20],"(ICS)":[21],"and":[22,26,144,215],"reductions":[23],"mortality":[25],"rehospitalization":[27,143],"observational":[29,257],"studies.":[30,258],"Using":[31],"time-dependent":[32],"versions":[33],"statistical":[35],"survival":[36],"models,":[37],"these":[38],"suggested":[41],"immortal":[42,80,219,243],"time":[43,81,183,220,244],"bias":[44,59,82,245],"as":[45],"responsible":[46],"for":[47,68,248],"proposed":[49],"beneficial":[50],"association.":[51],"OBJECTIVES:":[52],"We":[53,240],"explored":[54],"extent":[56],"this":[58],"a":[61,69,114,181,185,223],"study":[62,137],"patients":[64,100,179],"with":[65,74,190,226,253],"COPD":[66,72],"monitored":[67],"year":[70],"from":[71,124,157],"discharge":[73,111],"two":[75],"designs":[76],"free":[77,217],"any":[79],"General":[85],"Practice":[86],"Research":[87],"Database":[88],"United":[91],"Kingdom.":[92],"METHODS:":[93],"In":[94,129],"Design":[95,130],"1,":[96],"we":[97,132],"used":[98],"only":[99],"whose":[101],"treatment":[102,165],"status":[103,214],"was":[104],"defined":[105],"on":[106,118],"same":[108],"day":[109],"to":[112,149,151,164,212,228],"obtain":[113],"matched":[115,146,174,202],"based":[117],"propensity":[119,172],"scores,":[120],"which":[121],"were":[122],"derived":[123],"patient-level":[126],"baseline":[127],"characteristics.":[128],"2,":[131],"identified":[133],"all":[134],"who":[139],"experienced":[140],"death":[141],"or":[142],"then":[145],"each":[147],"case":[148],"up":[150],"four":[152],"noncases":[153],"by":[154],"randomly":[155],"sampling":[156],"risk":[160,187,250],"sets":[161],"without":[162,180,210],"regard":[163,211],"status.":[166],"MEASUREMENTS":[167],"AND":[168],"MAIN":[169],"RESULTS:":[170],"The":[171,201],"scores":[173],"analysis":[176,205],"786":[178],"wait":[182],"found":[184],"significant":[186],"reduction":[188,251],"associated":[189,252],"use":[191],"ICS:":[193],"hazard":[194,235],"ratio,":[195,236],"0.69":[196],"(95%":[197],"confidence":[198],"interval,":[199],"0.52-0.93).":[200],"nested":[203],"case-control":[204],"2,222":[207],"patients,":[208],"designed":[209],"exposure":[213,227,255],"hence":[216],"bias,":[221],"gave":[222],"similar":[224],"association":[225],"ICS":[229,254],"last":[232],"6-month":[233],"period:":[234],"0.71":[237],"(0.56-0.90).":[238],"CONCLUSIONS:":[239],"conclude":[241],"that":[242],"cannot":[246],"account":[247]},"counts_by_year":[{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":1},{"year":2022,"cited_by_count":2},{"year":2021,"cited_by_count":1},{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":3},{"year":2017,"cited_by_count":2},{"year":2016,"cited_by_count":2},{"year":2015,"cited_by_count":4},{"year":2014,"cited_by_count":3},{"year":2013,"cited_by_count":2},{"year":2012,"cited_by_count":3}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}
