{"id":"https://openalex.org/W1968320472","doi":"https://doi.org/10.2478/s11535-013-0245-2","title":"Influence of the extraction solvent on antioxidant activity of Althaea officinalis L. root extracts","display_name":"Influence of the extraction solvent on antioxidant activity of Althaea officinalis L. root extracts","publication_year":2013,"publication_date":"2013-09-21","ids":{"openalex":"https://openalex.org/W1968320472","doi":"https://doi.org/10.2478/s11535-013-0245-2","mag":"1968320472"},"language":"en","primary_location":{"id":"doi:10.2478/s11535-013-0245-2","doi":"https://doi.org/10.2478/s11535-013-0245-2","is_oa":true,"landing_page_url":"https://doi.org/10.2478/s11535-013-0245-2","pdf_url":"https://www.degruyter.com/document/doi/10.2478/s11535-013-0245-2/pdf","source":{"id":"https://openalex.org/S119941230","display_name":"Open Life Sciences","issn_l":"1895-104X","issn":["1895-104X","1644-3632","2391-5412"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-d","jufo-1","norway-1","poland-40","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320322","host_organization_name":"De Gruyter Open","host_organization_lineage":["https://openalex.org/P4310320322","https://openalex.org/P4310313990"],"host_organization_lineage_names":["De Gruyter Open","De Gruyter"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Open Life Sciences","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.degruyter.com/document/doi/10.2478/s11535-013-0245-2/pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5009430943","display_name":"Niko Benbassat","orcid":"https://orcid.org/0000-0001-8876-2728","observed_orcids":["https://orcid.org/0000-0001-8876-2728"]},"institutions":[{"id":"https://openalex.org/I30147112","display_name":"Medical University of Sofia","ror":"https://ror.org/01n9zy652","country_code":"BG","type":"education","lineage":["https://openalex.org/I30147112"]}],"countries":["BG"],"is_corresponding":false,"raw_author_name":"Niko Benbassat","raw_affiliation_strings":["Department of Pharmacognosy, Medical University of Sofia, 1000, Sofia, Bulgaria"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pharmacognosy, Medical University of Sofia, 1000, Sofia, Bulgaria","institution_ids":["https://openalex.org/I30147112"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5019346291","display_name":"Krassimira Yoncheva","orcid":"https://orcid.org/0000-0003-2704-3054","observed_orcids":["https://orcid.org/0000-0003-2704-3054"]},"institutions":[{"id":"https://openalex.org/I30147112","display_name":"Medical University of Sofia","ror":"https://ror.org/01n9zy652","country_code":"BG","type":"education","lineage":["https://openalex.org/I30147112"]}],"countries":["BG"],"is_corresponding":false,"raw_author_name":"Krassimira Yoncheva","raw_affiliation_strings":["Department of Pharmaceutical Technology, Medical University of Sofia, 1000, Sofia, Bulgaria"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pharmaceutical Technology, Medical University of Sofia, 1000, Sofia, Bulgaria","institution_ids":["https://openalex.org/I30147112"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5022517471","display_name":"Vera A. Hadjimitova","orcid":"https://orcid.org/0000-0001-7735-5406","observed_orcids":["https://orcid.org/0000-0001-7735-5406"]},"institutions":[{"id":"https://openalex.org/I30147112","display_name":"Medical University of Sofia","ror":"https://ror.org/01n9zy652","country_code":"BG","type":"education","lineage":["https://openalex.org/I30147112"]}],"countries":["BG"],"is_corresponding":false,"raw_author_name":"Vera Hadjimitova","raw_affiliation_strings":["Department of Physics and Biophysics, Medical Faculty, Medical University of Sofia, 1431, Sofia, Bulgaria"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Physics and Biophysics, Medical Faculty, Medical University of Sofia, 1431, Sofia, Bulgaria","institution_ids":["https://openalex.org/I30147112"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5078649132","display_name":"Nadya G. Hristova-Avakumova","orcid":"https://orcid.org/0000-0001-7763-9791","observed_orcids":["https://orcid.org/0000-0001-7763-9791"]},"institutions":[{"id":"https://openalex.org/I30147112","display_name":"Medical University of Sofia","ror":"https://ror.org/01n9zy652","country_code":"BG","type":"education","lineage":["https://openalex.org/I30147112"]}],"countries":["BG"],"is_corresponding":false,"raw_author_name":"Nadia Hristova","raw_affiliation_strings":["Department of Physics and Biophysics, Medical Faculty, Medical University of Sofia, 1431, Sofia, Bulgaria"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Physics and Biophysics, Medical Faculty, Medical University of Sofia, 1431, Sofia, Bulgaria","institution_ids":["https://openalex.org/I30147112"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5064332179","display_name":"Spiro Konstantinov","orcid":"https://orcid.org/0000-0002-3017-6088","observed_orcids":["https://orcid.org/0000-0002-3017-6088"]},"institutions":[{"id":"https://openalex.org/I30147112","display_name":"Medical University of Sofia","ror":"https://ror.org/01n9zy652","country_code":"BG","type":"education","lineage":["https://openalex.org/I30147112"]}],"countries":["BG"],"is_corresponding":false,"raw_author_name":"Spiro Konstantinov","raw_affiliation_strings":["Department of Pharmacology, Faculty of Pharmacy, Medical University of Sofia, 1000, Sofia, Bulgaria"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pharmacology, Faculty of Pharmacy, Medical University of Sofia, 1000, Sofia, Bulgaria","institution_ids":["https://openalex.org/I30147112"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5109949431","display_name":"Nikolai Lambov","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I30147112","display_name":"Medical University of Sofia","ror":"https://ror.org/01n9zy652","country_code":"BG","type":"education","lineage":["https://openalex.org/I30147112"]}],"countries":["BG"],"is_corresponding":false,"raw_author_name":"Nikolai Lambov","raw_affiliation_strings":["Department of Pharmaceutical Technology, Medical University of Sofia, 1000, Sofia, Bulgaria"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pharmaceutical Technology, Medical University of Sofia, 1000, Sofia, Bulgaria","institution_ids":["https://openalex.org/I30147112"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I30147112"],"apc_list":{"value":2100,"currency":"EUR","value_usd":2373},"apc_paid":{"value":2100,"currency":"EUR","value_usd":2373},"fwci":0.6602,"has_fulltext":true,"cited_by_count":22,"citation_normalized_percentile":{"value":0.64084752,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":87,"max":98},"biblio":{"volume":"9","issue":"2","first_page":"182","last_page":"188"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10035","display_name":"Phytochemicals and Antioxidant Activities","score":0.9390000104904175,"subfield":{"id":"https://openalex.org/subfields/2704","display_name":"Biochemistry (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10035","display_name":"Phytochemicals and Antioxidant Activities","score":0.9390000104904175,"subfield":{"id":"https://openalex.org/subfields/2704","display_name":"Biochemistry (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T14521","display_name":"Medicinal Plant Research","score":0.04610000178217888,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11613","display_name":"Phytochemistry and Biological Activities","score":0.006200000178068876,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/althaea-officinalis","display_name":"Althaea officinalis","score":1.0},{"id":"https://openalex.org/keywords/root-extract","display_name":"root extract","score":0.5019999742507935},{"id":"https://openalex.org/keywords/antioxidant-activity","display_name":"antioxidant activity","score":0.906000018119812},{"id":"https://openalex.org/keywords/extractants","display_name":"extraction solvents","score":0.9129999876022339},{"id":"https://openalex.org/keywords/ethanol-water-extract","display_name":"ethanol-water extract","score":0.5770000219345093},{"id":"https://openalex.org/keywords/aqueous-extract","display_name":"aqueous extract","score":0.8429999947547913},{"id":"https://openalex.org/keywords/abts-assay","display_name":"ABTS radical scavenging","score":0.9509999752044678},{"id":"https://openalex.org/keywords/lipid-peroxidation","display_name":"lipid peroxidation","score":0.9700000286102295},{"id":"https://openalex.org/keywords/phenolic-content","display_name":"phenolic content","score":0.9409999847412109},{"id":"https://openalex.org/keywords/flavonoids","display_name":"flavonoids","score":0.8970000147819519},{"id":"https://openalex.org/keywords/immunomodulation","display_name":"immunomodulation","score":0.8820000290870667}],"concepts":[{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.8806139230728149},{"id":"https://openalex.org/C2778004101","wikidata":"https://www.wikidata.org/wiki/Q133948","display_name":"Antioxidant","level":2,"score":0.8012622594833374},{"id":"https://openalex.org/C2781031786","wikidata":"https://www.wikidata.org/wiki/Q287582","display_name":"ABTS","level":4,"score":0.762823224067688},{"id":"https://openalex.org/C4725764","wikidata":"https://www.wikidata.org/wiki/Q844704","display_name":"Extraction (chemistry)","level":2,"score":0.6458276510238647},{"id":"https://openalex.org/C2780161600","wikidata":"https://www.wikidata.org/wiki/Q153","display_name":"Ethanol","level":2,"score":0.6454571485519409},{"id":"https://openalex.org/C2779054382","wikidata":"https://www.wikidata.org/wiki/Q72185287","display_name":"Flavonoid","level":3,"score":0.5879375338554382},{"id":"https://openalex.org/C43617362","wikidata":"https://www.wikidata.org/wiki/Q170050","display_name":"Chromatography","level":1,"score":0.5278056859970093},{"id":"https://openalex.org/C2780471494","wikidata":"https://www.wikidata.org/wiki/Q146505","display_name":"Solvent","level":2,"score":0.5119043588638306},{"id":"https://openalex.org/C2780886089","wikidata":"https://www.wikidata.org/wiki/Q7079617","display_name":"Officinalis","level":2,"score":0.4964504837989807},{"id":"https://openalex.org/C556039675","wikidata":"https://www.wikidata.org/wiki/Q771035","display_name":"Traditional medicine","level":1,"score":0.3862939774990082},{"id":"https://openalex.org/C31903555","wikidata":"https://www.wikidata.org/wiki/Q1637030","display_name":"Food science","level":1,"score":0.33901745080947876},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.26191067695617676},{"id":"https://openalex.org/C2781401929","wikidata":"https://www.wikidata.org/wiki/Q5205953","display_name":"DPPH","level":3,"score":0.22956490516662598},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.0}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.2478/s11535-013-0245-2","doi":"https://doi.org/10.2478/s11535-013-0245-2","is_oa":true,"landing_page_url":"https://doi.org/10.2478/s11535-013-0245-2","pdf_url":"https://www.degruyter.com/document/doi/10.2478/s11535-013-0245-2/pdf","source":{"id":"https://openalex.org/S119941230","display_name":"Open Life Sciences","issn_l":"1895-104X","issn":["1895-104X","1644-3632","2391-5412"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-d","jufo-1","norway-1","poland-40","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320322","host_organization_name":"De Gruyter Open","host_organization_lineage":["https://openalex.org/P4310320322","https://openalex.org/P4310313990"],"host_organization_lineage_names":["De Gruyter Open","De Gruyter"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Open Life Sciences","raw_type":"journal-article"},{"id":"pmh:oai:doaj.org/article:8f1f7228012f42a89248cc08c4277002","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/8f1f7228012f42a89248cc08c4277002","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Open Life Sciences, Vol 9, Iss 2, Pp 182-188 (2014)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.2478/s11535-013-0245-2","doi":"https://doi.org/10.2478/s11535-013-0245-2","is_oa":true,"landing_page_url":"https://doi.org/10.2478/s11535-013-0245-2","pdf_url":"https://www.degruyter.com/document/doi/10.2478/s11535-013-0245-2/pdf","source":{"id":"https://openalex.org/S119941230","display_name":"Open Life Sciences","issn_l":"1895-104X","issn":["1895-104X","1644-3632","2391-5412"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-d","jufo-1","norway-1","poland-40","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320322","host_organization_name":"De Gruyter Open","host_organization_lineage":["https://openalex.org/P4310320322","https://openalex.org/P4310313990"],"host_organization_lineage_names":["De Gruyter Open","De Gruyter"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Open Life Sciences","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.46810001134872437,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W1968320472.pdf","grobid_xml":"https://content.openalex.org/works/W1968320472.grobid-xml"},"referenced_works_count":31,"referenced_works":["https://openalex.org/W79019264","https://openalex.org/W215268669","https://openalex.org/W1559903407","https://openalex.org/W1603650505","https://openalex.org/W1968230519","https://openalex.org/W1977108112","https://openalex.org/W1981798465","https://openalex.org/W2006125991","https://openalex.org/W2012991711","https://openalex.org/W2026921121","https://openalex.org/W2033089640","https://openalex.org/W2035576602","https://openalex.org/W2039460182","https://openalex.org/W2045103284","https://openalex.org/W2045742793","https://openalex.org/W2046263314","https://openalex.org/W2052599717","https://openalex.org/W2063524454","https://openalex.org/W2069042257","https://openalex.org/W2071657929","https://openalex.org/W2074985627","https://openalex.org/W2075405390","https://openalex.org/W2088921410","https://openalex.org/W2091543808","https://openalex.org/W2093951158","https://openalex.org/W2100057735","https://openalex.org/W2123133309","https://openalex.org/W2314857003","https://openalex.org/W2482538433","https://openalex.org/W4255641184","https://openalex.org/W4285719527"],"related_works":["https://openalex.org/W4406915518","https://openalex.org/W4220713087","https://openalex.org/W2075405390","https://openalex.org/W2625970021","https://openalex.org/W2809363509","https://openalex.org/W4405117863","https://openalex.org/W2770834827","https://openalex.org/W4285324468","https://openalex.org/W2188439644","https://openalex.org/W4245249500"],"abstract_inverted_index":{"Abstract":[0],"Althaea":[1],"officinalis":[2,21],"(Malvaceae)":[3],"is":[4,9,34,48],"a":[5],"well-known":[6],"plant":[7],"that":[8,37,87],"widely":[10],"distributed":[11],"throughout":[12],"the":[13,43,51,88,102,117,126,144,148,165],"world.":[14],"Aqueous":[15],"and":[16,30,80,130,140,161],"hydroalcoholic":[17],"extracts":[18,66,103,118,168],"from":[19],"A.":[20],"root":[22,56,65],"are":[23,40],"used":[24],"mainly":[25],"because":[26],"of":[27,55,64,123,164],"their":[28,186],"antitussive":[29],"expectorant":[31],"activity.":[32,114],"It":[33],"well":[35,111,158],"known":[36,49],"these":[38],"activities":[39],"based":[41],"on":[42,174],"polysaccharide":[44],"composition,":[45],"but":[46,179],"little":[47],"about":[50],"possible":[52],"antioxidant":[53,62,99,113,187],"activity":[54,63,136],"extract.":[57],"The":[58,84,167],"present":[59],"study":[60],"evaluated":[61],"prepared":[67,90],"with":[68,91,147,159],"different":[69],"extraction":[70,94,108],"solvents":[71],"applying":[72],"ABTS\u00b7+":[73,138],"(2,2\u2032-azino-bis(3-ethylbenzothiazoline-6-sulphonic":[74],"acid),":[75],"hypochlorous":[76],"acid":[77],"scavenging":[78,135],"assay":[79],"iron-induced":[81],"lipid":[82],"peroxidation.":[83],"results":[85,155],"showed":[86,110,133],"extract":[89,145],"water":[92],"as":[93,107],"solvent":[95,128],"did":[96,169],"not":[97,170],"possess":[98],"activity,":[100],"whereas":[101],"obtained":[104,119,146],"using":[105],"ethanol:water":[106],"agent":[109],"pronounced":[112],"In":[115],"particular,":[116],"at":[120],"low":[121],"concentration":[122,151],"ethanol":[124,150],"in":[125],"mixed":[127],"(50:50":[129],"70:30,":[131],"v/v)":[132],"higher":[134,149],"for":[137],"radicals":[139],"hypochlorite":[141],"ions":[142],"than":[143],"(90:10,":[152],"v/v).":[153],"These":[154],"correlated":[156],"very":[157],"phenolic":[160],"flavonoid":[162],"content":[163],"extracts.":[166],"show":[171],"cytotoxic":[172],"effect":[173],"human":[175],"BV-173":[176],"leukemic":[177],"cells":[178],"may":[180],"have":[181],"immunomodulating":[182],"effects":[183],"due":[184],"to":[185],"properties.":[188]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":1},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":2},{"year":2021,"cited_by_count":3},{"year":2020,"cited_by_count":5},{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":3},{"year":2017,"cited_by_count":1},{"year":2015,"cited_by_count":1},{"year":2014,"cited_by_count":2}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2016-06-24T00:00:00"}