{"id":"https://openalex.org/W1968308246","doi":"https://doi.org/10.1097/00002826-200401000-00009","title":"Dopaminergic Hypersensitivity In Patients With Parkinson Disease And Migraine","display_name":"Dopaminergic Hypersensitivity In Patients With Parkinson Disease And Migraine","publication_year":2004,"publication_date":"2004-01-01","ids":{"openalex":"https://openalex.org/W1968308246","doi":"https://doi.org/10.1097/00002826-200401000-00009","mag":"1968308246","pmid":"https://pubmed.ncbi.nlm.nih.gov/15090934"},"language":"en","primary_location":{"id":"doi:10.1097/00002826-200401000-00009","doi":"https://doi.org/10.1097/00002826-200401000-00009","is_oa":false,"landing_page_url":"https://doi.org/10.1097/00002826-200401000-00009","pdf_url":null,"source":{"id":"https://openalex.org/S3349026","display_name":"Clinical Neuropharmacology","issn_l":"0362-5664","issn":["0362-5664","1537-162X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","medline","norway-1","poland-40","russia-white-list-3"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clinical Neuropharmacology","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5112581431","display_name":"Esther Cubo","orcid":"https://orcid.org/0000-0003-0018-1182","observed_orcids":["https://orcid.org/0000-0003-0018-1182"]},"institutions":[{"id":"https://openalex.org/I1285301757","display_name":"Rush University Medical Center","ror":"https://ror.org/01j7c0b24","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1285301757"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Esther Cubo","raw_affiliation_strings":["Sanatorio del Rosario, Clinica de la Zarzuela, Department of Neurology, Madrid, Spain. ecubo@inicia.es","Department of Neurological Sciences, Section of Movement Disorders, and \u2021Department of Preventive Medicine, Section of Biostatistics, Rush-Presbyterian-St. Luke's Medical Center, Chicago, Illinois, USA","Sanatorio del Rosario, Clinica de la Zarzuela, Department of Neurology, Madrid, Spain"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Sanatorio del Rosario, Clinica de la Zarzuela, Department of Neurology, Madrid, Spain. ecubo@inicia.es","institution_ids":[]},{"raw_affiliation_string":"Department of Neurological Sciences, Section of Movement Disorders, and \u2021Department of Preventive Medicine, Section of Biostatistics, Rush-Presbyterian-St. Luke's Medical Center, Chicago, Illinois, USA","institution_ids":["https://openalex.org/I1285301757"]},{"raw_affiliation_string":"Sanatorio del Rosario, Clinica de la Zarzuela, Department of Neurology, Madrid, Spain","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5068446591","display_name":"Katie Kompoliti","orcid":"https://orcid.org/0000-0002-4194-8944","observed_orcids":["https://orcid.org/0000-0002-4194-8944"]},"institutions":[{"id":"https://openalex.org/I1285301757","display_name":"Rush University Medical Center","ror":"https://ror.org/01j7c0b24","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1285301757"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Katie Kompoliti","raw_affiliation_strings":["Department of Neurological Sciences, Section of Movement Disorders, and \u2021Department of Preventive Medicine, Section of Biostatistics, Rush-Presbyterian-St. Luke's Medical Center, Chicago, Illinois, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurological Sciences, Section of Movement Disorders, and \u2021Department of Preventive Medicine, Section of Biostatistics, Rush-Presbyterian-St. Luke's Medical Center, Chicago, Illinois, USA","institution_ids":["https://openalex.org/I1285301757"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5070294274","display_name":"Sue E. Leurgans","orcid":"https://orcid.org/0000-0003-2536-1665","observed_orcids":["https://orcid.org/0000-0003-2536-1665"]},"institutions":[{"id":"https://openalex.org/I1285301757","display_name":"Rush University Medical Center","ror":"https://ror.org/01j7c0b24","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1285301757"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Sue E. Leurgans","raw_affiliation_strings":["Department of Neurological Sciences, Section of Movement Disorders, and \u2021Department of Preventive Medicine, Section of Biostatistics, Rush-Presbyterian-St. Luke's Medical Center, Chicago, Illinois, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurological Sciences, Section of Movement Disorders, and \u2021Department of Preventive Medicine, Section of Biostatistics, Rush-Presbyterian-St. Luke's Medical Center, Chicago, Illinois, USA","institution_ids":["https://openalex.org/I1285301757"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5068057129","display_name":"Rema Raman","orcid":"https://orcid.org/0000-0002-4096-6390","observed_orcids":["https://orcid.org/0000-0002-4096-6390"]},"institutions":[{"id":"https://openalex.org/I1285301757","display_name":"Rush University Medical Center","ror":"https://ror.org/01j7c0b24","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1285301757"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Rema Raman","raw_affiliation_strings":["Department of Neurological Sciences, Section of Movement Disorders, and \u2021Department of Preventive Medicine, Section of Biostatistics, Rush-Presbyterian-St. Luke's Medical Center, Chicago, Illinois, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurological Sciences, Section of Movement Disorders, and \u2021Department of Preventive Medicine, Section of Biostatistics, Rush-Presbyterian-St. Luke's Medical Center, Chicago, Illinois, USA","institution_ids":["https://openalex.org/I1285301757"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5112581431"],"corresponding_institution_ids":["https://openalex.org/I1285301757"],"apc_list":null,"apc_paid":null,"fwci":0.4245,"has_fulltext":false,"cited_by_count":20,"citation_normalized_percentile":{"value":0.65470446,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":98},"biblio":{"volume":"27","issue":"1","first_page":"30","last_page":"32"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10085","display_name":"Parkinson's Disease Mechanisms and Treatments","score":0.9932000041007996,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Clinical Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10085","display_name":"Parkinson's Disease Mechanisms and Treatments","score":0.9932000041007996,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Clinical Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10919","display_name":"Deep Brain Stimulation and Movement Disorders","score":0.0024999999441206455,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Clinical Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10498","display_name":"Migraine and Headache Studies","score":0.00039999998989515007,"subfield":{"id":"https://openalex.org/subfields/2738","display_name":"Psychiatry and Mental health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/parkinson-s-disease","display_name":"Parkinson's disease","score":0.9779999852180481},{"id":"https://openalex.org/keywords/migraine","display_name":"migraine","score":0.9940000176429749},{"id":"https://openalex.org/keywords/levodopa-response","display_name":"levodopa response","score":0.7540000081062317},{"id":"https://openalex.org/keywords/motor-impairment","display_name":"motor impairment","score":0.8349999785423279},{"id":"https://openalex.org/keywords/on-state","display_name":"ON state","score":0.5410000085830688},{"id":"https://openalex.org/keywords/dopamine-agonists","display_name":"dopamine agonists","score":0.6029999852180481}],"concepts":[{"id":"https://openalex.org/C2778541695","wikidata":"https://www.wikidata.org/wiki/Q133823","display_name":"Migraine","level":2,"score":0.9349788427352905},{"id":"https://openalex.org/C137183658","wikidata":"https://www.wikidata.org/wiki/Q461076","display_name":"Dopaminergic","level":3,"score":0.811832070350647},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.7433017492294312},{"id":"https://openalex.org/C2779734285","wikidata":"https://www.wikidata.org/wiki/Q11085","display_name":"Parkinson's disease","level":3,"score":0.7294676303863525},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.5170038938522339},{"id":"https://openalex.org/C2779281540","wikidata":"https://www.wikidata.org/wiki/Q5062122","display_name":"Central nervous system disease","level":2,"score":0.47078412771224976},{"id":"https://openalex.org/C42219234","wikidata":"https://www.wikidata.org/wiki/Q131130","display_name":"Anesthesia","level":1,"score":0.38240718841552734},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.29545122385025024},{"id":"https://openalex.org/C513476851","wikidata":"https://www.wikidata.org/wiki/Q170304","display_name":"Dopamine","level":2,"score":0.16536840796470642}],"mesh":[{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000369","descriptor_name":"Aged, 80 and over","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000978","descriptor_name":"Antiparkinson Agents","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":false},{"descriptor_ui":"D000978","descriptor_name":"Antiparkinson Agents","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D003430","descriptor_name":"Cross-Sectional Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004298","descriptor_name":"Dopamine","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007980","descriptor_name":"Levodopa","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":false},{"descriptor_ui":"D007980","descriptor_name":"Levodopa","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008881","descriptor_name":"Migraine Disorders","qualifier_ui":"Q000139","qualifier_name":"chemically induced","is_major_topic":false},{"descriptor_ui":"D008881","descriptor_name":"Migraine Disorders","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":false},{"descriptor_ui":"D008881","descriptor_name":"Migraine Disorders","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D009043","descriptor_name":"Motor Activity","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D010300","descriptor_name":"Parkinson Disease","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":false},{"descriptor_ui":"D010300","descriptor_name":"Parkinson Disease","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D012720","descriptor_name":"Severity of Illness Index","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016022","descriptor_name":"Case-Control Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016037","descriptor_name":"Single-Blind Method","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018491","descriptor_name":"Dopamine Agonists","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":false},{"descriptor_ui":"D018491","descriptor_name":"Dopamine Agonists","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D020820","descriptor_name":"Dyskinesias","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D020820","descriptor_name":"Dyskinesias","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1097/00002826-200401000-00009","doi":"https://doi.org/10.1097/00002826-200401000-00009","is_oa":false,"landing_page_url":"https://doi.org/10.1097/00002826-200401000-00009","pdf_url":null,"source":{"id":"https://openalex.org/S3349026","display_name":"Clinical Neuropharmacology","issn_l":"0362-5664","issn":["0362-5664","1537-162X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","medline","norway-1","poland-40","russia-white-list-3"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clinical Neuropharmacology","raw_type":"journal-article"},{"id":"pmid:15090934","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/15090934","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clinical neuropharmacology","raw_type":"Clinical Trial"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.98580002784729}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":11,"referenced_works":["https://openalex.org/W1965291031","https://openalex.org/W2024347935","https://openalex.org/W2051332182","https://openalex.org/W2055122214","https://openalex.org/W2061922630","https://openalex.org/W2064996887","https://openalex.org/W2080990317","https://openalex.org/W2095143892","https://openalex.org/W2099275034","https://openalex.org/W2142961788","https://openalex.org/W2410227703"],"related_works":["https://openalex.org/W2207144965","https://openalex.org/W2095143892","https://openalex.org/W2302782533","https://openalex.org/W2080990317","https://openalex.org/W2412100735","https://openalex.org/W2068957321","https://openalex.org/W4403589115","https://openalex.org/W4411606411","https://openalex.org/W2414918266","https://openalex.org/W6922532296"],"abstract_inverted_index":{"Because":[0],"migraine":[1,21,48,59,71,83],"has":[2],"been":[3],"associated":[4,86],"with":[5,14,17,38,47,55,72,87],"dopaminergic":[6,24,88],"receptor":[7],"hypersensitivity,":[8],"the":[9,65,73,80],"authors":[10],"hypothesized":[11],"that":[12,82],"patients":[13,33,37,46,51,69],"Parkinson":[15,31,39,56],"disease":[16,32,40,57],"current":[18],"or":[19],"prior":[20],"have":[22],"better":[23],"response":[25],"and":[26,43,49,58],"less":[27],"motor":[28,62],"disability":[29],"than":[30,68],"without":[34,52,70],"migraine.":[35],"Twenty-eight":[36],"were":[41],"included":[42],"matched":[44],"(10":[45],"18":[50],"migraine).":[53],"Patients":[54],"showed":[60],"greater":[61],"improvement":[63],"during":[64],"ON":[66],"state":[67],"same":[74],"medication":[75],"exposure.":[76],"These":[77],"data":[78],"support":[79],"hypothesis":[81],"may":[84],"be":[85],"hypersensitivity.":[89]},"counts_by_year":[{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":2},{"year":2018,"cited_by_count":1},{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":1},{"year":2015,"cited_by_count":1},{"year":2013,"cited_by_count":5},{"year":2012,"cited_by_count":2}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}