{"id":"https://openalex.org/W1968196386","doi":"https://doi.org/10.1515/znb-1980-0418","title":"Sila-Pharmaka, 16. Mitt. [1]. Sila-Analoga von Nifedipin-\u00e4hnlichen 4-Aryl-2.6-dimethyl-1.4-dihydropyridin-3.5-dicarbons\u00e4ure-dialkylestern, I. / Sila-Drugs, 16th Communication [1]. Sila-Analogues of Nifedipine-Like Dialkyl 4-Aryl-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylates, I.","display_name":"Sila-Pharmaka, 16. Mitt. [1]. Sila-Analoga von Nifedipin-\u00e4hnlichen 4-Aryl-2.6-dimethyl-1.4-dihydropyridin-3.5-dicarbons\u00e4ure-dialkylestern, I. / Sila-Drugs, 16th Communication [1]. Sila-Analogues of Nifedipine-Like Dialkyl 4-Aryl-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylates, I.","publication_year":1980,"publication_date":"1980-04-01","ids":{"openalex":"https://openalex.org/W1968196386","doi":"https://doi.org/10.1515/znb-1980-0418","mag":"1968196386"},"language":"en","primary_location":{"id":"doi:10.1515/znb-1980-0418","doi":"https://doi.org/10.1515/znb-1980-0418","is_oa":true,"landing_page_url":"https://doi.org/10.1515/znb-1980-0418","pdf_url":null,"source":{"id":"https://openalex.org/S104732370","display_name":"Zeitschrift f\u00fcr Naturforschung B","issn_l":"0044-3174","issn":["0044-3174","0341-0447","0932-0776","1865-7117"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","jufo-1","norway-1","poland-40","russia-white-list-3"],"host_organization":"https://openalex.org/P4310313990","host_organization_name":"De Gruyter","host_organization_lineage":["https://openalex.org/P4310313990"],"host_organization_lineage_names":["De Gruyter"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Zeitschrift f\u00fcr Naturforschung B","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://doi.org/10.1515/znb-1980-0418","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5047144179","display_name":"Reinhold Tacke","orcid":"https://orcid.org/0000-0003-4532-2647","observed_orcids":["https://orcid.org/0000-0003-4532-2647"]},"institutions":[{"id":"https://openalex.org/I94509681","display_name":"Technische Universit\u00e4t Braunschweig","ror":"https://ror.org/010nsgg66","country_code":"DE","type":"education","lineage":["https://openalex.org/I94509681"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"R. Tacke","raw_affiliation_strings":["Institut f\u00fcr Anorganische Chemie der Technischen Universittit Braunschweig, PockelsstraBe 4, D-3300 Braunschweig"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institut f\u00fcr Anorganische Chemie der Technischen Universittit Braunschweig, PockelsstraBe 4, D-3300 Braunschweig","institution_ids":["https://openalex.org/I94509681"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5067980836","display_name":"Anke Bentlage","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I94509681","display_name":"Technische Universit\u00e4t Braunschweig","ror":"https://ror.org/010nsgg66","country_code":"DE","type":"education","lineage":["https://openalex.org/I94509681"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"A. Bentlage","raw_affiliation_strings":["Institut f\u00fcr Anorganische Chemie der Technischen Universittit Braunschweig, PockelsstraBe 4, D-3300 Braunschweig"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institut f\u00fcr Anorganische Chemie der Technischen Universittit Braunschweig, PockelsstraBe 4, D-3300 Braunschweig","institution_ids":["https://openalex.org/I94509681"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109073902","display_name":"Robertson Towart","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I67348948","display_name":"Bayer (Germany)","ror":"https://ror.org/04hmn8g73","country_code":"DE","type":"company","lineage":["https://openalex.org/I67348948"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"R. Towart","raw_affiliation_strings":["Pharma-Forschungszentrum der Bayer AG, Postach 101709, D-5600 Wuppertal-Elberfeld"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Pharma-Forschungszentrum der Bayer AG, Postach 101709, D-5600 Wuppertal-Elberfeld","institution_ids":["https://openalex.org/I67348948"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111204072","display_name":"Hinrich Meyer","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I67348948","display_name":"Bayer (Germany)","ror":"https://ror.org/04hmn8g73","country_code":"DE","type":"company","lineage":["https://openalex.org/I67348948"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"H. Meyer","raw_affiliation_strings":["Pharma-Forschungszentrum der Bayer AG, Postach 101709, D-5600 Wuppertal-Elberfeld"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Pharma-Forschungszentrum der Bayer AG, Postach 101709, D-5600 Wuppertal-Elberfeld","institution_ids":["https://openalex.org/I67348948"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111608874","display_name":"Friedrich Bossert","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I67348948","display_name":"Bayer (Germany)","ror":"https://ror.org/04hmn8g73","country_code":"DE","type":"company","lineage":["https://openalex.org/I67348948"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"F. Bossert","raw_affiliation_strings":["Pharma-Forschungszentrum der Bayer AG, Postach 101709, D-5600 Wuppertal-Elberfeld"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Pharma-Forschungszentrum der Bayer AG, Postach 101709, D-5600 Wuppertal-Elberfeld","institution_ids":["https://openalex.org/I67348948"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5046266618","display_name":"W. Vater","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I67348948","display_name":"Bayer (Germany)","ror":"https://ror.org/04hmn8g73","country_code":"DE","type":"company","lineage":["https://openalex.org/I67348948"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"W. Vater","raw_affiliation_strings":["Pharma-Forschungszentrum der Bayer AG, Postach 101709, D-5600 Wuppertal-Elberfeld"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Pharma-Forschungszentrum der Bayer AG, Postach 101709, D-5600 Wuppertal-Elberfeld","institution_ids":["https://openalex.org/I67348948"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5021011495","display_name":"Kurt Stoepel","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I67348948","display_name":"Bayer (Germany)","ror":"https://ror.org/04hmn8g73","country_code":"DE","type":"company","lineage":["https://openalex.org/I67348948"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"K. Stoepel","raw_affiliation_strings":["Pharma-Forschungszentrum der Bayer AG, Postach 101709, D-5600 Wuppertal-Elberfeld"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Pharma-Forschungszentrum der Bayer AG, Postach 101709, D-5600 Wuppertal-Elberfeld","institution_ids":["https://openalex.org/I67348948"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":2400,"currency":"EUR","value_usd":2712},"apc_paid":{"value":2400,"currency":"EUR","value_usd":2712},"fwci":2.7698,"has_fulltext":true,"cited_by_count":7,"citation_normalized_percentile":{"value":0.87311293,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"35","issue":"4","first_page":"494","last_page":"501"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11441","display_name":"Organoboron and organosilicon chemistry","score":0.7250999808311462,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T11441","display_name":"Organoboron and organosilicon chemistry","score":0.7250999808311462,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T13649","display_name":"Advanced Synthetic Organic Chemistry","score":0.0689999982714653,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10274","display_name":"Heterocyclic Compound Synthesis and Bioactivity","score":0.050999999046325684,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/nifedipine-analogues","display_name":"nifedipine analogues","score":0.8320000171661377},{"id":"https://openalex.org/keywords/1-4-dihydropyridines","display_name":"1,4-dihydropyridines","score":0.9700000286102295},{"id":"https://openalex.org/keywords/dialkyl-esters","display_name":"dialkyl esters","score":0.7850000262260437},{"id":"https://openalex.org/keywords/organosilicon-compounds","display_name":"organosilicon compounds","score":0.7739999890327454},{"id":"https://openalex.org/keywords/antispasmodic-activity","display_name":"antispasmodic activity","score":0.9610000252723694},{"id":"https://openalex.org/keywords/vasodilating-activity","display_name":"vasodilating activity","score":0.9449999928474426},{"id":"https://openalex.org/keywords/antihypertensive-effect","display_name":"antihypertensive effect","score":0.9589999914169312},{"id":"https://openalex.org/keywords/calcium-channel-blockers","display_name":"calcium channel blockers","score":0.8159999847412109}],"concepts":[{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.6918225288391113},{"id":"https://openalex.org/C2776798904","wikidata":"https://www.wikidata.org/wiki/Q93978","display_name":"Antispasmodic","level":2,"score":0.6336030960083008},{"id":"https://openalex.org/C2779066535","wikidata":"https://www.wikidata.org/wiki/Q39111","display_name":"Nifedipine","level":3,"score":0.6294939517974854},{"id":"https://openalex.org/C2781076698","wikidata":"https://www.wikidata.org/wiki/Q718074","display_name":"Aryl","level":3,"score":0.5547274947166443},{"id":"https://openalex.org/C155647269","wikidata":"https://www.wikidata.org/wiki/Q243455","display_name":"Medicinal chemistry","level":1,"score":0.4484423100948334},{"id":"https://openalex.org/C71240020","wikidata":"https://www.wikidata.org/wiki/Q186011","display_name":"Stereochemistry","level":1,"score":0.35924339294433594},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.18640264868736267},{"id":"https://openalex.org/C2780263894","wikidata":"https://www.wikidata.org/wiki/Q335268","display_name":"Alkyl","level":2,"score":0.09634628891944885},{"id":"https://openalex.org/C519063684","wikidata":"https://www.wikidata.org/wiki/Q706","display_name":"Calcium","level":2,"score":0.08772516250610352},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.05579948425292969},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.0}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.1515/znb-1980-0418","doi":"https://doi.org/10.1515/znb-1980-0418","is_oa":true,"landing_page_url":"https://doi.org/10.1515/znb-1980-0418","pdf_url":null,"source":{"id":"https://openalex.org/S104732370","display_name":"Zeitschrift f\u00fcr Naturforschung B","issn_l":"0044-3174","issn":["0044-3174","0341-0447","0932-0776","1865-7117"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","jufo-1","norway-1","poland-40","russia-white-list-3"],"host_organization":"https://openalex.org/P4310313990","host_organization_name":"De Gruyter","host_organization_lineage":["https://openalex.org/P4310313990"],"host_organization_lineage_names":["De Gruyter"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Zeitschrift f\u00fcr Naturforschung B","raw_type":"journal-article"},{"id":"pmh:oai:opus.bibliothek.uni-wuerzburg.de:6911","doi":null,"is_oa":true,"landing_page_url":"https://opus.bibliothek.uni-wuerzburg.de/frontdoor/index/index/docId/6911","pdf_url":"https://opus.bibliothek.uni-wuerzburg.de/files/6911/Tacke18.pdf","source":{"id":"https://openalex.org/S4306401635","display_name":"Online Publication Service of W\u00fcrzburg University (W\u00fcrzburg University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I25974101","host_organization_name":"University of W\u00fcrzburg","host_organization_lineage":["https://openalex.org/I25974101"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"article"}],"best_oa_location":{"id":"doi:10.1515/znb-1980-0418","doi":"https://doi.org/10.1515/znb-1980-0418","is_oa":true,"landing_page_url":"https://doi.org/10.1515/znb-1980-0418","pdf_url":null,"source":{"id":"https://openalex.org/S104732370","display_name":"Zeitschrift f\u00fcr Naturforschung B","issn_l":"0044-3174","issn":["0044-3174","0341-0447","0932-0776","1865-7117"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","jufo-1","norway-1","poland-40","russia-white-list-3"],"host_organization":"https://openalex.org/P4310313990","host_organization_name":"De Gruyter","host_organization_lineage":["https://openalex.org/P4310313990"],"host_organization_lineage_names":["De Gruyter"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Zeitschrift f\u00fcr Naturforschung B","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.5683000087738037,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W1968196386.pdf","grobid_xml":"https://content.openalex.org/works/W1968196386.grobid-xml"},"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W4251966699","https://openalex.org/W7112646663","https://openalex.org/W2345992257","https://openalex.org/W7015283067","https://openalex.org/W7006000147","https://openalex.org/W1993624584","https://openalex.org/W2071007602","https://openalex.org/W2154110619","https://openalex.org/W2070709681","https://openalex.org/W2029828754"],"abstract_inverted_index":{"The":[0,56],"nifedipine-like":[1],"1,4-dihydropyridines":[2],"10a":[3],"and":[4,13,29,35,42,45,53,59,67],"11a":[5],"as":[6,8],"well":[7],"their":[9,30,40,46],"sila-analogues":[10],"10b,":[11,22,64],"10c,":[12,23,65],"11b":[14,27,68],"were":[15,37,69],"synthesized":[16],"for":[17],"the":[18],"first":[19],"time.":[20],"10a,":[21,63],"11":[24],"a":[25],",":[26,28],"precursors":[31],"8a,":[32],"8b,":[33],"9a,":[34],"9b":[36],"characterized":[38],"by":[39,49],"physical":[41],"chemical":[43],"properties,":[44],"structures":[47],"confirmed":[48],"analyses,":[50],"1H":[51],"NMR":[52],"mass":[54],"spectroscopy.":[55],"antispasmodic,":[57],"vasodilating,":[58],"antihypertensive":[60],"properties":[61],"of":[62],"11a,":[66],"compared.":[70]},"counts_by_year":[],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}