{"id":"https://openalex.org/W1968113936","doi":"https://doi.org/10.1038/nchembio0908-515","title":"Chemical biology in China takes on signal transduction","display_name":"Chemical biology in China takes on signal transduction","publication_year":2008,"publication_date":"2008-08-18","ids":{"openalex":"https://openalex.org/W1968113936","doi":"https://doi.org/10.1038/nchembio0908-515","mag":"1968113936","pmid":"https://pubmed.ncbi.nlm.nih.gov/18711374"},"language":"en","primary_location":{"id":"doi:10.1038/nchembio0908-515","doi":"https://doi.org/10.1038/nchembio0908-515","is_oa":false,"landing_page_url":"https://doi.org/10.1038/nchembio0908-515","pdf_url":null,"source":{"id":"https://openalex.org/S51309854","display_name":"Nature Chemical Biology","issn_l":"1552-4450","issn":["1552-4450","1552-4469"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nature Chemical Biology","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5001392142","display_name":"Hualiang Jiang","orcid":"https://orcid.org/0000-0003-0656-6315","observed_orcids":["https://orcid.org/0000-0003-0656-6315"]},"institutions":[{"id":"https://openalex.org/I19820366","display_name":"Chinese Academy of Sciences","ror":"https://ror.org/034t30j35","country_code":"CN","type":"government","lineage":["https://openalex.org/I19820366"]},{"id":"https://openalex.org/I4210112820","display_name":"Shanghai Institute of Materia Medica","ror":"https://ror.org/022syn853","country_code":"CN","type":"facility","lineage":["https://openalex.org/I19820366","https://openalex.org/I4210112820"]},{"id":"https://openalex.org/I4391767758","display_name":"State Key Laboratory of Drug Research","ror":"https://ror.org/058t7w767","country_code":"CN","type":"facility","lineage":["https://openalex.org/I19820366","https://openalex.org/I4210112820","https://openalex.org/I4391767758"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Hualiang Jiang","raw_affiliation_strings":["Drug Discovery and Design Center, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 555 Zu Chong Zhi Road, Shanghai 201203, China. hljiang@mail.schcnc.ac.cn","Hualiang Jiang is in the Drug Discovery and Design Center, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 555 Zu Chong Zhi Road, Shanghai 201203, China hljiang@mail.schcnc.ac.cn,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Drug Discovery and Design Center, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 555 Zu Chong Zhi Road, Shanghai 201203, China. hljiang@mail.schcnc.ac.cn","institution_ids":["https://openalex.org/I19820366","https://openalex.org/I4210112820","https://openalex.org/I4391767758"]},{"raw_affiliation_string":"Hualiang Jiang is in the Drug Discovery and Design Center, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 555 Zu Chong Zhi Road, Shanghai 201203, China hljiang@mail.schcnc.ac.cn,","institution_ids":["https://openalex.org/I19820366","https://openalex.org/I4210112820","https://openalex.org/I4391767758"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5028026003","display_name":"Jiarui Wu","orcid":"https://orcid.org/0000-0001-8791-2325","observed_orcids":["https://orcid.org/0000-0001-8791-2325"]},"institutions":[{"id":"https://openalex.org/I19820366","display_name":"Chinese Academy of Sciences","ror":"https://ror.org/034t30j35","country_code":"CN","type":"government","lineage":["https://openalex.org/I19820366"]},{"id":"https://openalex.org/I4210106477","display_name":"Shanghai Institutes for Biological Sciences","ror":"https://ror.org/011rf9d86","country_code":"CN","type":"facility","lineage":["https://openalex.org/I19820366","https://openalex.org/I4210106477"]},{"id":"https://openalex.org/I4210121447","display_name":"Center for Excellence in Molecular Cell Science","ror":"https://ror.org/02rrdvm96","country_code":"CN","type":"facility","lineage":["https://openalex.org/I19820366","https://openalex.org/I4210121447"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jiarui Wu","raw_affiliation_strings":["Jiarui Wu is in the Shanghai Institute of Biochemistry and Cell Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, 218 Yueyang Road, Shanghai 200031, China,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Jiarui Wu is in the Shanghai Institute of Biochemistry and Cell Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, 218 Yueyang Road, Shanghai 200031, China,","institution_ids":["https://openalex.org/I19820366","https://openalex.org/I4210106477","https://openalex.org/I4210121447"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101503601","display_name":"Lihe Zhang","orcid":"https://orcid.org/0009-0009-6580-5743","observed_orcids":["https://orcid.org/0009-0009-6580-5743"]},"institutions":[{"id":"https://openalex.org/I20231570","display_name":"Peking University","ror":"https://ror.org/02v51f717","country_code":"CN","type":"education","lineage":["https://openalex.org/I20231570"]},{"id":"https://openalex.org/I4391768132","display_name":"State Key Laboratory of Natural and Biomimetic Drugs","ror":"https://ror.org/049mqh532","country_code":"CN","type":"facility","lineage":["https://openalex.org/I20231570","https://openalex.org/I4391768132"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Lihe Zhang","raw_affiliation_strings":["Lihe Zhang is in the State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, 38 Xue Yuan Road, Beijing 100083, China,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Lihe Zhang is in the State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, 38 Xue Yuan Road, Beijing 100083, China,","institution_ids":["https://openalex.org/I20231570","https://openalex.org/I4391768132"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111527497","display_name":"Wenping Liang","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I102398690","display_name":"National Natural Science Foundation of China","ror":"https://ror.org/01h0zpd94","country_code":"CN","type":"government","lineage":["https://openalex.org/I102398690"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Wenping Liang","raw_affiliation_strings":["Wenping Liang, Feixue Gao, Xuelian Feng, Canping Du and Yongjun Chen are in the National Natural Science Foundation of China, 83 Shuang Qing Road, Beijing 100085,China. chenyj@mail.nsfc.gov.cn,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Wenping Liang, Feixue Gao, Xuelian Feng, Canping Du and Yongjun Chen are in the National Natural Science Foundation of China, 83 Shuang Qing Road, Beijing 100085,China. chenyj@mail.nsfc.gov.cn,","institution_ids":["https://openalex.org/I102398690"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5088612292","display_name":"Feixue Gao","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I102398690","display_name":"National Natural Science Foundation of China","ror":"https://ror.org/01h0zpd94","country_code":"CN","type":"government","lineage":["https://openalex.org/I102398690"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Feixue Gao","raw_affiliation_strings":["Wenping Liang, Feixue Gao, Xuelian Feng, Canping Du and Yongjun Chen are in the National Natural Science Foundation of China, 83 Shuang Qing Road, Beijing 100085,China. chenyj@mail.nsfc.gov.cn,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Wenping Liang, Feixue Gao, Xuelian Feng, Canping Du and Yongjun Chen are in the National Natural Science Foundation of China, 83 Shuang Qing Road, Beijing 100085,China. chenyj@mail.nsfc.gov.cn,","institution_ids":["https://openalex.org/I102398690"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5053303858","display_name":"Canping Du","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I102398690","display_name":"National Natural Science Foundation of China","ror":"https://ror.org/01h0zpd94","country_code":"CN","type":"government","lineage":["https://openalex.org/I102398690"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Canping Du","raw_affiliation_strings":["Wenping Liang, Feixue Gao, Xuelian Feng, Canping Du and Yongjun Chen are in the National Natural Science Foundation of China, 83 Shuang Qing Road, Beijing 100085,China. chenyj@mail.nsfc.gov.cn,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Wenping Liang, Feixue Gao, Xuelian Feng, Canping Du and Yongjun Chen are in the National Natural Science Foundation of China, 83 Shuang Qing Road, Beijing 100085,China. chenyj@mail.nsfc.gov.cn,","institution_ids":["https://openalex.org/I102398690"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5033069064","display_name":"Xuelian Feng","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I102398690","display_name":"National Natural Science Foundation of China","ror":"https://ror.org/01h0zpd94","country_code":"CN","type":"government","lineage":["https://openalex.org/I102398690"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xuelian Feng","raw_affiliation_strings":["Wenping Liang, Feixue Gao, Xuelian Feng, Canping Du and Yongjun Chen are in the National Natural Science Foundation of China, 83 Shuang Qing Road, Beijing 100085,China. chenyj@mail.nsfc.gov.cn,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Wenping Liang, Feixue Gao, Xuelian Feng, Canping Du and Yongjun Chen are in the National Natural Science Foundation of China, 83 Shuang Qing Road, Beijing 100085,China. chenyj@mail.nsfc.gov.cn,","institution_ids":["https://openalex.org/I102398690"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5100371663","display_name":"Yongjun Chen","orcid":"https://orcid.org/0000-0001-5081-7762","observed_orcids":["https://orcid.org/0000-0001-5081-7762"]},"institutions":[{"id":"https://openalex.org/I102398690","display_name":"National Natural Science Foundation of China","ror":"https://ror.org/01h0zpd94","country_code":"CN","type":"government","lineage":["https://openalex.org/I102398690"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yongjun Chen","raw_affiliation_strings":["Wenping Liang, Feixue Gao, Xuelian Feng, Canping Du and Yongjun Chen are in the National Natural Science Foundation of China, 83 Shuang Qing Road, Beijing 100085,China. chenyj@mail.nsfc.gov.cn,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Wenping Liang, Feixue Gao, Xuelian Feng, Canping Du and Yongjun Chen are in the National Natural Science Foundation of China, 83 Shuang Qing Road, Beijing 100085,China. chenyj@mail.nsfc.gov.cn,","institution_ids":["https://openalex.org/I102398690"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":8,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":12690,"currency":"USD","value_usd":12690},"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":5,"citation_normalized_percentile":{"value":0.0,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":87,"max":95},"biblio":{"volume":"4","issue":"9","first_page":"515","last_page":"518"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T14185","display_name":"Research, Science, and Academia","score":0.6133000254631042,"subfield":{"id":"https://openalex.org/subfields/1405","display_name":"Management of Technology and Innovation"},"field":{"id":"https://openalex.org/fields/14","display_name":"Business, Management and Accounting"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}},"topics":[{"id":"https://openalex.org/T14185","display_name":"Research, Science, and Academia","score":0.6133000254631042,"subfield":{"id":"https://openalex.org/subfields/1405","display_name":"Management of Technology and Innovation"},"field":{"id":"https://openalex.org/fields/14","display_name":"Business, Management and Accounting"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}},{"id":"https://openalex.org/T12766","display_name":"Interdisciplinary Research and Collaboration","score":0.13650000095367432,"subfield":{"id":"https://openalex.org/subfields/1207","display_name":"History and Philosophy of Science"},"field":{"id":"https://openalex.org/fields/12","display_name":"Arts and Humanities"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}},{"id":"https://openalex.org/T12168","display_name":"Health and Medical Research Impacts","score":0.047600001096725464,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/chemical-biology","display_name":"chemical biology","score":0.8730000257492065},{"id":"https://openalex.org/keywords/signal-transduction","display_name":"signal transduction","score":0.9940000176429749},{"id":"https://openalex.org/keywords/research-funding","display_name":"research funding","score":0.8629999756813049},{"id":"https://openalex.org/keywords/national-natural-science-foundation-of-china","display_name":"National Natural Science Foundation of China","score":0.9449999928474426},{"id":"https://openalex.org/keywords/research-funding-policy","display_name":"research funding policy","score":0.40299999713897705}],"concepts":[{"id":"https://openalex.org/C191935318","wikidata":"https://www.wikidata.org/wiki/Q148","display_name":"China","level":2,"score":0.6568799018859863},{"id":"https://openalex.org/C62478195","wikidata":"https://www.wikidata.org/wiki/Q828130","display_name":"Signal transduction","level":2,"score":0.6436751484870911},{"id":"https://openalex.org/C2780966255","wikidata":"https://www.wikidata.org/wiki/Q5474306","display_name":"Foundation (evidence)","level":2,"score":0.6152962446212769},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.5063022375106812},{"id":"https://openalex.org/C171852809","wikidata":"https://www.wikidata.org/wiki/Q731154","display_name":"Chemical biology","level":2,"score":0.49483388662338257},{"id":"https://openalex.org/C191908910","wikidata":"https://www.wikidata.org/wiki/Q862838","display_name":"Synthetic biology","level":2,"score":0.4652838110923767},{"id":"https://openalex.org/C152662350","wikidata":"https://www.wikidata.org/wiki/Q815297","display_name":"Systems biology","level":2,"score":0.45685723423957825},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.40461841225624084},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.3972225785255432},{"id":"https://openalex.org/C17744445","wikidata":"https://www.wikidata.org/wiki/Q36442","display_name":"Political science","level":0,"score":0.23290309309959412},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.20985111594200134},{"id":"https://openalex.org/C199539241","wikidata":"https://www.wikidata.org/wiki/Q7748","display_name":"Law","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D001695","descriptor_name":"Biology","qualifier_ui":"Q000191","qualifier_name":"economics","is_major_topic":true},{"descriptor_ui":"D001695","descriptor_name":"Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D001695","descriptor_name":"Biology","qualifier_ui":"Q000639","qualifier_name":"trends","is_major_topic":true},{"descriptor_ui":"D002017","descriptor_name":"Budgets","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002621","descriptor_name":"Chemistry","qualifier_ui":"Q000191","qualifier_name":"economics","is_major_topic":true},{"descriptor_ui":"D002621","descriptor_name":"Chemistry","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D002621","descriptor_name":"Chemistry","qualifier_ui":"Q000639","qualifier_name":"trends","is_major_topic":true},{"descriptor_ui":"D002681","descriptor_name":"China","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005380","descriptor_name":"Financing, Government","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006077","descriptor_name":"Government Agencies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012106","descriptor_name":"Research","qualifier_ui":"Q000191","qualifier_name":"economics","is_major_topic":true},{"descriptor_ui":"D012106","descriptor_name":"Research","qualifier_ui":"Q000331","qualifier_name":"legislation & jurisprudence","is_major_topic":true},{"descriptor_ui":"D012106","descriptor_name":"Research","qualifier_ui":"Q000639","qualifier_name":"trends","is_major_topic":true},{"descriptor_ui":"D015398","descriptor_name":"Signal Transduction","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1038/nchembio0908-515","doi":"https://doi.org/10.1038/nchembio0908-515","is_oa":false,"landing_page_url":"https://doi.org/10.1038/nchembio0908-515","pdf_url":null,"source":{"id":"https://openalex.org/S51309854","display_name":"Nature Chemical Biology","issn_l":"1552-4450","issn":["1552-4450","1552-4469"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nature Chemical Biology","raw_type":"journal-article"},{"id":"pmid:18711374","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/18711374","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nature chemical biology","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":24,"referenced_works":["https://openalex.org/W1977665068","https://openalex.org/W1978443443","https://openalex.org/W1982214865","https://openalex.org/W2012191603","https://openalex.org/W2019166246","https://openalex.org/W2028296524","https://openalex.org/W2029362544","https://openalex.org/W2031296931","https://openalex.org/W2039011144","https://openalex.org/W2046705094","https://openalex.org/W2046754487","https://openalex.org/W2047003553","https://openalex.org/W2051062317","https://openalex.org/W2054978326","https://openalex.org/W2077834462","https://openalex.org/W2080960938","https://openalex.org/W2085073123","https://openalex.org/W2086057828","https://openalex.org/W2097281218","https://openalex.org/W2101283273","https://openalex.org/W2148379230","https://openalex.org/W2158444866","https://openalex.org/W2166376626","https://openalex.org/W2184391500"],"related_works":["https://openalex.org/W2406080465","https://openalex.org/W3156313655","https://openalex.org/W4399174825","https://openalex.org/W2087461587","https://openalex.org/W2059441324","https://openalex.org/W4386160997","https://openalex.org/W4399174785","https://openalex.org/W4408939371","https://openalex.org/W1478740546","https://openalex.org/W4246768597"],"abstract_inverted_index":null,"counts_by_year":[{"year":2023,"cited_by_count":2},{"year":2021,"cited_by_count":1},{"year":2018,"cited_by_count":1},{"year":2013,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}