{"id":"https://openalex.org/W1967417752","doi":"https://doi.org/10.1080/10428190601059720","title":"Dose-attenuated radioimmunotherapy with tositumomab and iodine 131 tositumomab in patients with recurrent non-Hodgkin's lymphoma (NHL) and extensive bone marrow involvement","display_name":"Dose-attenuated radioimmunotherapy with tositumomab and iodine 131 tositumomab in patients with recurrent non-Hodgkin's lymphoma (NHL) and extensive bone marrow involvement","publication_year":2007,"publication_date":"2007-01-01","ids":{"openalex":"https://openalex.org/W1967417752","doi":"https://doi.org/10.1080/10428190601059720","mag":"1967417752","pmid":"https://pubmed.ncbi.nlm.nih.gov/17325895"},"language":"en","primary_location":{"id":"doi:10.1080/10428190601059720","doi":"https://doi.org/10.1080/10428190601059720","is_oa":false,"landing_page_url":"https://doi.org/10.1080/10428190601059720","pdf_url":null,"source":{"id":"https://openalex.org/S27064115","display_name":"Leukemia & lymphoma/Leukemia and lymphoma","issn_l":"1026-8022","issn":["1026-8022","1029-2403","1042-8194"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320547","host_organization_name":"Taylor & Francis","host_organization_lineage":["https://openalex.org/P4310320547","https://openalex.org/P4310320449"],"host_organization_lineage_names":["Taylor & Francis","Informa"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Leukemia &amp; Lymphoma","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5016951239","display_name":"Jodi Victoria Mones","orcid":"https://orcid.org/0000-0002-1327-775X","observed_orcids":["https://orcid.org/0000-0002-1327-775X"]},"institutions":[{"id":"https://openalex.org/I1340179700","display_name":"NewYork\u2013Presbyterian Hospital","ror":"https://ror.org/03gzbrs57","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1340179700"]},{"id":"https://openalex.org/I205783295","display_name":"Cornell University","ror":"https://ror.org/05bnh6r87","country_code":"US","type":"education","lineage":["https://openalex.org/I205783295"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jodi V. Mones","raw_affiliation_strings":["Center for Lymphoma and Myeloma, Division of Hematology/Oncology, Weill Medical College of Cornell University and New York Presbyterian Hospital, New York, NY 10021, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Lymphoma and Myeloma, Division of Hematology/Oncology, Weill Medical College of Cornell University and New York Presbyterian Hospital, New York, NY 10021, USA","institution_ids":["https://openalex.org/I1340179700","https://openalex.org/I205783295"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5082720713","display_name":"Morton Coleman","orcid":"https://orcid.org/0000-0002-8516-2513","observed_orcids":["https://orcid.org/0000-0002-8516-2513"]},"institutions":[{"id":"https://openalex.org/I1340179700","display_name":"NewYork\u2013Presbyterian Hospital","ror":"https://ror.org/03gzbrs57","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1340179700"]},{"id":"https://openalex.org/I205783295","display_name":"Cornell University","ror":"https://ror.org/05bnh6r87","country_code":"US","type":"education","lineage":["https://openalex.org/I205783295"]},{"id":"https://openalex.org/I4387153466","display_name":"Weill Cornell Medicine","ror":"https://ror.org/02r109517","country_code":"US","type":"education","lineage":["https://openalex.org/I205783295","https://openalex.org/I4387153466"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Morton Coleman","raw_affiliation_strings":["Center for Lymphoma and Myeloma, Divisions of Hematology/Oncology, Nuclear Medicine, and Hematopathology, Weill Medical College of Cornell University and New York Presbyterian Hospital, New York, NY, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Lymphoma and Myeloma, Divisions of Hematology/Oncology, Nuclear Medicine, and Hematopathology, Weill Medical College of Cornell University and New York Presbyterian Hospital, New York, NY, USA","institution_ids":["https://openalex.org/I1340179700","https://openalex.org/I205783295","https://openalex.org/I4387153466"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5030681199","display_name":"Lale Kostako\u011flu","orcid":"https://orcid.org/0000-0002-2419-348X","observed_orcids":["https://orcid.org/0000-0002-2419-348X"]},"institutions":[{"id":"https://openalex.org/I1340179700","display_name":"NewYork\u2013Presbyterian Hospital","ror":"https://ror.org/03gzbrs57","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1340179700"]},{"id":"https://openalex.org/I205783295","display_name":"Cornell University","ror":"https://ror.org/05bnh6r87","country_code":"US","type":"education","lineage":["https://openalex.org/I205783295"]},{"id":"https://openalex.org/I4387153466","display_name":"Weill Cornell Medicine","ror":"https://ror.org/02r109517","country_code":"US","type":"education","lineage":["https://openalex.org/I205783295","https://openalex.org/I4387153466"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Lale Kostakoglu","raw_affiliation_strings":["Center for Lymphoma and Myeloma, Divisions of Hematology/Oncology, Nuclear Medicine, and Hematopathology, Weill Medical College of Cornell University and New York Presbyterian Hospital, New York, NY, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Lymphoma and Myeloma, Divisions of Hematology/Oncology, Nuclear Medicine, and Hematopathology, Weill Medical College of Cornell University and New York Presbyterian Hospital, New York, NY, USA","institution_ids":["https://openalex.org/I1340179700","https://openalex.org/I205783295","https://openalex.org/I4387153466"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5013974745","display_name":"Richard R. Furman","orcid":"https://orcid.org/0000-0003-1677-7626","observed_orcids":["https://orcid.org/0000-0003-1677-7626"]},"institutions":[{"id":"https://openalex.org/I1340179700","display_name":"NewYork\u2013Presbyterian Hospital","ror":"https://ror.org/03gzbrs57","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1340179700"]},{"id":"https://openalex.org/I205783295","display_name":"Cornell University","ror":"https://ror.org/05bnh6r87","country_code":"US","type":"education","lineage":["https://openalex.org/I205783295"]},{"id":"https://openalex.org/I4387153466","display_name":"Weill Cornell Medicine","ror":"https://ror.org/02r109517","country_code":"US","type":"education","lineage":["https://openalex.org/I205783295","https://openalex.org/I4387153466"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Richard R. Furman","raw_affiliation_strings":["Center for Lymphoma and Myeloma, Divisions of Hematology/Oncology, Nuclear Medicine, and Hematopathology, Weill Medical College of Cornell University and New York Presbyterian Hospital, New York, NY, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Lymphoma and Myeloma, Divisions of Hematology/Oncology, Nuclear Medicine, and Hematopathology, Weill Medical College of Cornell University and New York Presbyterian Hospital, New York, NY, USA","institution_ids":["https://openalex.org/I1340179700","https://openalex.org/I205783295","https://openalex.org/I4387153466"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5064702056","display_name":"Amy Chadburn","orcid":"https://orcid.org/0000-0002-9499-8638","observed_orcids":["https://orcid.org/0000-0002-9499-8638"]},"institutions":[{"id":"https://openalex.org/I1340179700","display_name":"NewYork\u2013Presbyterian Hospital","ror":"https://ror.org/03gzbrs57","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1340179700"]},{"id":"https://openalex.org/I205783295","display_name":"Cornell University","ror":"https://ror.org/05bnh6r87","country_code":"US","type":"education","lineage":["https://openalex.org/I205783295"]},{"id":"https://openalex.org/I4387153466","display_name":"Weill Cornell Medicine","ror":"https://ror.org/02r109517","country_code":"US","type":"education","lineage":["https://openalex.org/I205783295","https://openalex.org/I4387153466"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Amy Chadburn","raw_affiliation_strings":["Center for Lymphoma and Myeloma, Divisions of Hematology/Oncology, Nuclear Medicine, and Hematopathology, Weill Medical College of Cornell University and New York Presbyterian Hospital, New York, NY, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Lymphoma and Myeloma, Divisions of Hematology/Oncology, Nuclear Medicine, and Hematopathology, Weill Medical College of Cornell University and New York Presbyterian Hospital, New York, NY, USA","institution_ids":["https://openalex.org/I1340179700","https://openalex.org/I205783295","https://openalex.org/I4387153466"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5071121646","display_name":"Tsiporah B. Shore","orcid":"https://orcid.org/0000-0001-6033-0747","observed_orcids":["https://orcid.org/0000-0001-6033-0747"]},"institutions":[{"id":"https://openalex.org/I1340179700","display_name":"NewYork\u2013Presbyterian Hospital","ror":"https://ror.org/03gzbrs57","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1340179700"]},{"id":"https://openalex.org/I205783295","display_name":"Cornell University","ror":"https://ror.org/05bnh6r87","country_code":"US","type":"education","lineage":["https://openalex.org/I205783295"]},{"id":"https://openalex.org/I4387153466","display_name":"Weill Cornell Medicine","ror":"https://ror.org/02r109517","country_code":"US","type":"education","lineage":["https://openalex.org/I205783295","https://openalex.org/I4387153466"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Tsiporah B. Shore","raw_affiliation_strings":["Center for Lymphoma and Myeloma, Divisions of Hematology/Oncology, Nuclear Medicine, and Hematopathology, Weill Medical College of Cornell University and New York Presbyterian Hospital, New York, NY, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Lymphoma and Myeloma, Divisions of Hematology/Oncology, Nuclear Medicine, and Hematopathology, Weill Medical College of Cornell University and New York Presbyterian Hospital, New York, NY, USA","institution_ids":["https://openalex.org/I1340179700","https://openalex.org/I205783295","https://openalex.org/I4387153466"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5049499112","display_name":"Daniel Muss","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1340179700","display_name":"NewYork\u2013Presbyterian Hospital","ror":"https://ror.org/03gzbrs57","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1340179700"]},{"id":"https://openalex.org/I205783295","display_name":"Cornell University","ror":"https://ror.org/05bnh6r87","country_code":"US","type":"education","lineage":["https://openalex.org/I205783295"]},{"id":"https://openalex.org/I4387153466","display_name":"Weill Cornell Medicine","ror":"https://ror.org/02r109517","country_code":"US","type":"education","lineage":["https://openalex.org/I205783295","https://openalex.org/I4387153466"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Daniel Muss","raw_affiliation_strings":["Center for Lymphoma and Myeloma, Divisions of Hematology/Oncology, Nuclear Medicine, and Hematopathology, Weill Medical College of Cornell University and New York Presbyterian Hospital, New York, NY, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Lymphoma and Myeloma, Divisions of Hematology/Oncology, Nuclear Medicine, and Hematopathology, Weill Medical College of Cornell University and New York Presbyterian Hospital, New York, NY, USA","institution_ids":["https://openalex.org/I1340179700","https://openalex.org/I205783295","https://openalex.org/I4387153466"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5032503509","display_name":"PATRICIA S. STEWART","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2799696014","display_name":"Corixa Corporation","ror":"https://ror.org/01bthtp68","country_code":"US","type":"company","lineage":["https://openalex.org/I188950975","https://openalex.org/I2799696014","https://openalex.org/I4210114143"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Patricia Stewart","raw_affiliation_strings":["Corixa Corporation, S. San Francisco, CA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Corixa Corporation, S. San Francisco, CA, USA","institution_ids":["https://openalex.org/I2799696014"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110070377","display_name":"S. Kroll","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2799696014","display_name":"Corixa Corporation","ror":"https://ror.org/01bthtp68","country_code":"US","type":"company","lineage":["https://openalex.org/I188950975","https://openalex.org/I2799696014","https://openalex.org/I4210114143"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Stewart Kroll","raw_affiliation_strings":["Corixa Corporation, S. San Francisco, CA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Corixa Corporation, S. San Francisco, CA, USA","institution_ids":["https://openalex.org/I2799696014"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5020127308","display_name":"Shankar Vallabhajosula","orcid":"https://orcid.org/0000-0002-6638-3695","observed_orcids":["https://orcid.org/0000-0002-6638-3695"]},"institutions":[{"id":"https://openalex.org/I1340179700","display_name":"NewYork\u2013Presbyterian Hospital","ror":"https://ror.org/03gzbrs57","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1340179700"]},{"id":"https://openalex.org/I205783295","display_name":"Cornell University","ror":"https://ror.org/05bnh6r87","country_code":"US","type":"education","lineage":["https://openalex.org/I205783295"]},{"id":"https://openalex.org/I4387153466","display_name":"Weill Cornell Medicine","ror":"https://ror.org/02r109517","country_code":"US","type":"education","lineage":["https://openalex.org/I205783295","https://openalex.org/I4387153466"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Shankar Vallabhajosula","raw_affiliation_strings":["Center for Lymphoma and Myeloma, Divisions of Hematology/Oncology, Nuclear Medicine, and Hematopathology, Weill Medical College of Cornell University and New York Presbyterian Hospital, New York, NY, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Lymphoma and Myeloma, Divisions of Hematology/Oncology, Nuclear Medicine, and Hematopathology, Weill Medical College of Cornell University and New York Presbyterian Hospital, New York, NY, USA","institution_ids":["https://openalex.org/I1340179700","https://openalex.org/I205783295","https://openalex.org/I4387153466"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108553635","display_name":"Stanley J. Goldsmith","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1340179700","display_name":"NewYork\u2013Presbyterian Hospital","ror":"https://ror.org/03gzbrs57","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1340179700"]},{"id":"https://openalex.org/I205783295","display_name":"Cornell University","ror":"https://ror.org/05bnh6r87","country_code":"US","type":"education","lineage":["https://openalex.org/I205783295"]},{"id":"https://openalex.org/I4387153466","display_name":"Weill Cornell Medicine","ror":"https://ror.org/02r109517","country_code":"US","type":"education","lineage":["https://openalex.org/I205783295","https://openalex.org/I4387153466"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Stanley J. Goldsmith","raw_affiliation_strings":["Center for Lymphoma and Myeloma, Divisions of Hematology/Oncology, Nuclear Medicine, and Hematopathology, Weill Medical College of Cornell University and New York Presbyterian Hospital, New York, NY, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Lymphoma and Myeloma, Divisions of Hematology/Oncology, Nuclear Medicine, and Hematopathology, Weill Medical College of Cornell University and New York Presbyterian Hospital, New York, NY, USA","institution_ids":["https://openalex.org/I1340179700","https://openalex.org/I205783295","https://openalex.org/I4387153466"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5037882455","display_name":"John Paul Leonard","orcid":"https://orcid.org/0000-0002-5083-1115","observed_orcids":["https://orcid.org/0000-0002-5083-1115"]},"institutions":[{"id":"https://openalex.org/I1340179700","display_name":"NewYork\u2013Presbyterian Hospital","ror":"https://ror.org/03gzbrs57","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1340179700"]},{"id":"https://openalex.org/I205783295","display_name":"Cornell University","ror":"https://ror.org/05bnh6r87","country_code":"US","type":"education","lineage":["https://openalex.org/I205783295"]},{"id":"https://openalex.org/I4387153466","display_name":"Weill Cornell Medicine","ror":"https://ror.org/02r109517","country_code":"US","type":"education","lineage":["https://openalex.org/I205783295","https://openalex.org/I4387153466"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"John P. Leonard","raw_affiliation_strings":["Center for Lymphoma and Myeloma, Divisions of Hematology/Oncology, Nuclear Medicine, and Hematopathology, Weill Medical College of Cornell University and New York Presbyterian Hospital, New York, NY, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Lymphoma and Myeloma, Divisions of Hematology/Oncology, Nuclear Medicine, and Hematopathology, Weill Medical College of Cornell University and New York Presbyterian Hospital, New York, NY, USA","institution_ids":["https://openalex.org/I1340179700","https://openalex.org/I205783295","https://openalex.org/I4387153466"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5037882455"],"corresponding_institution_ids":["https://openalex.org/I1340179700","https://openalex.org/I205783295","https://openalex.org/I4387153466"],"apc_list":null,"apc_paid":null,"fwci":1.7497,"has_fulltext":false,"cited_by_count":14,"citation_normalized_percentile":{"value":0.82867597,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":96},"biblio":{"volume":"48","issue":"2","first_page":"342","last_page":"348"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11395","display_name":"Radiopharmaceutical Chemistry and Applications","score":0.9711999893188477,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11395","display_name":"Radiopharmaceutical Chemistry and Applications","score":0.9711999893188477,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10185","display_name":"Lymphoma Diagnosis and Treatment","score":0.024800000712275505,"subfield":{"id":"https://openalex.org/subfields/2734","display_name":"Pathology and Forensic Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11359","display_name":"Effects of Radiation Exposure","score":0.0010000000474974513,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/radioimmunotherapy","display_name":"radioimmunotherapy","score":0.9259999990463257},{"id":"https://openalex.org/keywords/tositumomab","display_name":"tositumomab","score":0.9950000047683716},{"id":"https://openalex.org/keywords/iodine-131-tositumomab","display_name":"iodine-131 tositumomab","score":0.9919999837875366},{"id":"https://openalex.org/keywords/non-hodgkin-lymphoma","display_name":"non-Hodgkin lymphoma","score":0.8970000147819519},{"id":"https://openalex.org/keywords/recurrent-lymphoma","display_name":"recurrent lymphoma","score":0.8209999799728394},{"id":"https://openalex.org/keywords/bone-marrow-involvement","display_name":"bone marrow involvement","score":0.9089999794960022},{"id":"https://openalex.org/keywords/dose-escalation","display_name":"dose escalation","score":0.7360000014305115},{"id":"https://openalex.org/keywords/hematological-toxicity","display_name":"hematologic toxicity","score":0.7820000052452087},{"id":"https://openalex.org/keywords/dose-limiting-toxicity","display_name":"dose-limiting toxicity","score":0.9049999713897705},{"id":"https://openalex.org/keywords/indolent-lymphoma","display_name":"indolent lymphoma","score":0.7279999852180481},{"id":"https://openalex.org/keywords/relapsed-refractory-lymphoma","display_name":"relapsed/refractory lymphoma","score":0.718999981880188}],"concepts":[{"id":"https://openalex.org/C2776146153","wikidata":"https://www.wikidata.org/wiki/Q7281276","display_name":"Radioimmunotherapy","level":4,"score":0.9114286303520203},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8100431561470032},{"id":"https://openalex.org/C2780007613","wikidata":"https://www.wikidata.org/wiki/Q546523","display_name":"Bone marrow","level":2,"score":0.5567787289619446},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.5203832387924194},{"id":"https://openalex.org/C2989005","wikidata":"https://www.wikidata.org/wiki/Q214963","display_name":"Nuclear medicine","level":1,"score":0.5065046548843384},{"id":"https://openalex.org/C2779338263","wikidata":"https://www.wikidata.org/wiki/Q208414","display_name":"Lymphoma","level":2,"score":0.48101502656936646},{"id":"https://openalex.org/C29730261","wikidata":"https://www.wikidata.org/wiki/Q274160","display_name":"Toxicity","level":2,"score":0.42588526010513306},{"id":"https://openalex.org/C90924648","wikidata":"https://www.wikidata.org/wiki/Q120569","display_name":"Gastroenterology","level":1,"score":0.42331811785697937},{"id":"https://openalex.org/C74133956","wikidata":"https://www.wikidata.org/wiki/Q4669824","display_name":"Absolute neutrophil count","level":4,"score":0.4221126139163971},{"id":"https://openalex.org/C143998085","wikidata":"https://www.wikidata.org/wiki/Q162555","display_name":"Oncology","level":1,"score":0.32691892981529236},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.32223618030548096},{"id":"https://openalex.org/C2777063308","wikidata":"https://www.wikidata.org/wiki/Q1435822","display_name":"Neutropenia","level":3,"score":0.15187102556228638},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.09312200546264648},{"id":"https://openalex.org/C542903549","wikidata":"https://www.wikidata.org/wiki/Q422248","display_name":"Monoclonal antibody","level":3,"score":0.0},{"id":"https://openalex.org/C159654299","wikidata":"https://www.wikidata.org/wiki/Q79460","display_name":"Antibody","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000911","descriptor_name":"Antibodies, Monoclonal","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D000970","descriptor_name":"Antineoplastic Agents","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D001853","descriptor_name":"Bone Marrow","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D004307","descriptor_name":"Dose-Response Relationship, Radiation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005240","descriptor_name":"Feasibility Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007457","descriptor_name":"Iodine Radioisotopes","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008224","descriptor_name":"Lymphoma, Follicular","qualifier_ui":"Q000532","qualifier_name":"radiotherapy","is_major_topic":false},{"descriptor_ui":"D008228","descriptor_name":"Lymphoma, Non-Hodgkin","qualifier_ui":"Q000532","qualifier_name":"radiotherapy","is_major_topic":true},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009364","descriptor_name":"Neoplasm Recurrence, Local","qualifier_ui":"Q000532","qualifier_name":"radiotherapy","is_major_topic":true},{"descriptor_ui":"D012074","descriptor_name":"Remission Induction","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016393","descriptor_name":"Lymphoma, B-Cell","qualifier_ui":"Q000532","qualifier_name":"radiotherapy","is_major_topic":false},{"descriptor_ui":"D016499","descriptor_name":"Radioimmunotherapy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D018951","descriptor_name":"Antigens, CD20","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1080/10428190601059720","doi":"https://doi.org/10.1080/10428190601059720","is_oa":false,"landing_page_url":"https://doi.org/10.1080/10428190601059720","pdf_url":null,"source":{"id":"https://openalex.org/S27064115","display_name":"Leukemia & lymphoma/Leukemia and lymphoma","issn_l":"1026-8022","issn":["1026-8022","1029-2403","1042-8194"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320547","host_organization_name":"Taylor & Francis","host_organization_lineage":["https://openalex.org/P4310320547","https://openalex.org/P4310320449"],"host_organization_lineage_names":["Taylor & Francis","Informa"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Leukemia &amp; Lymphoma","raw_type":"journal-article"},{"id":"pmid:17325895","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/17325895","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Leukemia & lymphoma","raw_type":"Clinical Trial, Phase I"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":1.0,"display_name":"Good health and well-being"}],"sustainable_development_goals_aurora":[{"id":"https://metadata.un.org/sdg/3","score":0.4099999964237213,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G2409183021","display_name":null,"funder_award_id":"K23 RR16814","funder_id":"https://openalex.org/F4320337375","funder_display_name":"National Center for Research Resources"},{"id":"https://openalex.org/G6327727180","display_name":"Novel Monoclonal Antibody Therapies for Lymphoma","funder_award_id":"K23RR016814","funder_id":"https://openalex.org/F4320337375","funder_display_name":"National Center for Research Resources"}],"funders":[{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337375","display_name":"National Center for Research Resources","ror":"https://ror.org/04pw6fb54"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":31,"referenced_works":["https://openalex.org/W97785538","https://openalex.org/W1222075461","https://openalex.org/W1563765846","https://openalex.org/W1778074652","https://openalex.org/W1885678484","https://openalex.org/W1892026381","https://openalex.org/W1915689252","https://openalex.org/W1933173754","https://openalex.org/W1995325395","https://openalex.org/W1999080103","https://openalex.org/W2000143004","https://openalex.org/W2009004107","https://openalex.org/W2013770655","https://openalex.org/W2014654561","https://openalex.org/W2025520495","https://openalex.org/W2052275340","https://openalex.org/W2084493022","https://openalex.org/W2084630860","https://openalex.org/W2117291755","https://openalex.org/W2119597015","https://openalex.org/W2132128887","https://openalex.org/W2148583561","https://openalex.org/W2185806117","https://openalex.org/W2204433245","https://openalex.org/W2231156824","https://openalex.org/W2245525451","https://openalex.org/W2256690185","https://openalex.org/W2267583049","https://openalex.org/W2273980314","https://openalex.org/W2338573834","https://openalex.org/W2417086497"],"related_works":["https://openalex.org/W1573890015","https://openalex.org/W4243864412","https://openalex.org/W2024451191","https://openalex.org/W2278498280","https://openalex.org/W2082145413","https://openalex.org/W1185955986","https://openalex.org/W3014745541","https://openalex.org/W4252663988","https://openalex.org/W2071174000","https://openalex.org/W1850839548"],"abstract_inverted_index":{"Radioimmunotherapy":[0],"(RIT)":[1],"with":[2,20,25,199,228,236],"tositumomab":[3,7,51,55,94,233],"and":[4,11,52,71,104,149,202,223,242],"iodine":[5,53,231],"131":[6,54,93,232],"can":[8,243],"produce":[9],"durable":[10],"complete":[12],"responses":[13,220],"in":[14,62,109,245],"relapsed/refractory":[15],"low-grade":[16],"Non-Hodgkin's":[17],"lymphoma.":[18],"Patients":[19,65,164],"bone":[21],"marrow":[22],"involvement":[23],"(BMI)":[24],"tumor":[26],">25%":[27,70,237],"of":[28,38,40,50,69,74,86,90,101,169,178,208,221],"the":[29,79,179],"intertrabecular":[30],"space":[31],"are":[32],"generally":[33],"excluded":[34],"from":[35,157],"RIT":[36,59,227],"because":[37],"risk":[39],"excessive":[41],"hematologic":[42,196,213],"toxicity.":[43],"The":[44],"authors":[45],"conducted":[46],"a":[47,97,110,167],"dose-escalation":[48],"study":[49],"to":[56,78,106,159],"determine":[57],"whether":[58],"is":[60],"feasible":[61],"this":[63],"population.":[64],"had":[66,165,195,218],"baseline":[67],"BMI":[68,155,204,238],"platelet":[72],"count":[73,121,133],">or=150,000/mm3.":[75],"In":[76],"contrast":[77],"usual":[80],"75":[81],"cGy":[82,108,148,186],"total":[83,98],"body":[84,99],"dose":[85,88,100,230],"radiation,":[87],"escalation":[89],"Iodine":[91],"I":[92],"began":[95],"at":[96,146,151,184,205],"45":[102,147,185],"cGy,":[103,193],"increased":[105],"55":[107,152,192],"second":[111],"cohort.":[112],"Dose-limiting":[113],"toxicity":[114,241],"(DLT)":[115],"was":[116],"defined":[117],"as":[118],"absolute":[119,131],"neutrophil":[120,132],"<500":[122],"cells/mm3":[123],"or":[124,130,135],"platelets":[125,136],"<25,000/mm3":[126],"for":[127,138,234],">17":[128],"days,":[129],"<750/mm3":[134],"<50,000/mm3":[137],">24":[139],"days.":[140],"Eleven":[141],"subjects":[142],"were":[143],"enrolled":[144],"(8":[145],"3":[150],"cGy).":[153],"Estimated":[154],"ranged":[156],"30":[158],"65%":[160],"(median":[161],"approximately":[162],"40%).":[163],"received":[166,191,212],"median":[168],"three":[170],"prior":[171],"chemotherapies":[172],"(range":[173],"1":[174,222],"-":[175],"6).":[176],"One":[177],"six":[180],"evaluable":[181],"patients":[182,190,211,217,235],"treated":[183],"experienced":[187],"DLT.":[188],"Three":[189,207],"one":[194],"DLT":[197],"concurrent":[198],"lymphoma":[200,246],"progression":[201],"extensive":[203],"relapse.":[206],"11":[209],"(27%)":[210],"supportive":[214],"care.":[215],"Two":[216],"objective":[219],"42.4+":[224],"months,":[225],"respectively.":[226],"attenuated":[229],"has":[239],"acceptable":[240],"result":[244],"responses.":[247]},"counts_by_year":[{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":1},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":1},{"year":2015,"cited_by_count":1},{"year":2014,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}