{"id":"https://openalex.org/W1967374891","doi":"https://doi.org/10.1155/2008/102737","title":"The Role of PPARs in Cancer","display_name":"The Role of PPARs in Cancer","publication_year":2008,"publication_date":"2008-01-01","ids":{"openalex":"https://openalex.org/W1967374891","doi":"https://doi.org/10.1155/2008/102737","mag":"1967374891","pmid":"https://pubmed.ncbi.nlm.nih.gov/18584037","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/2435221"},"language":"en","primary_location":{"id":"doi:10.1155/2008/102737","doi":"https://doi.org/10.1155/2008/102737","is_oa":true,"landing_page_url":"https://doi.org/10.1155/2008/102737","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1155/2008/102737","source":{"id":"https://openalex.org/S71649485","display_name":"PPAR Research","issn_l":"1687-4757","issn":["1687-4757","1687-4765"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","norway-1","poland-100","russia-white-list-1"],"host_organization":"https://openalex.org/P4310319869","host_organization_name":"Hindawi Publishing Corporation","host_organization_lineage":["https://openalex.org/P4310319869","https://openalex.org/P4310320595"],"host_organization_lineage_names":["Hindawi Publishing Corporation","Wiley"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PPAR Research","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1155/2008/102737","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5086288542","display_name":"Keisuke Tachibana","orcid":"https://orcid.org/0000-0003-0044-8772","observed_orcids":["https://orcid.org/0000-0003-0044-8772"]},"institutions":[{"id":"https://openalex.org/I98285908","display_name":"The University of Osaka","ror":"https://ror.org/035t8zc32","country_code":"JP","type":"education","lineage":["https://openalex.org/I98285908"]}],"countries":["JP"],"is_corresponding":true,"raw_author_name":"Keisuke Tachibana","raw_affiliation_strings":["Graduate School of Pharmaceutical Sciences, Osaka University, 1-6 Yamadaoka, Suita, Osaka 565-0871, Japan","Graduate School of Pharmaceutical Sciences, Osaka University, 1-6 Yamadaoka, Suita, Osaka 565-0871"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Graduate School of Pharmaceutical Sciences, Osaka University, 1-6 Yamadaoka, Suita, Osaka 565-0871, Japan","institution_ids":["https://openalex.org/I98285908"]},{"raw_affiliation_string":"Graduate School of Pharmaceutical Sciences, Osaka University, 1-6 Yamadaoka, Suita, Osaka 565-0871","institution_ids":["https://openalex.org/I98285908"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110206762","display_name":"Daisuke Yamasaki","orcid":"https://orcid.org/0009-0002-9326-4138","observed_orcids":["https://orcid.org/0009-0002-9326-4138"]},"institutions":[{"id":"https://openalex.org/I98285908","display_name":"The University of Osaka","ror":"https://ror.org/035t8zc32","country_code":"JP","type":"education","lineage":["https://openalex.org/I98285908"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Daisuke Yamasaki","raw_affiliation_strings":["Graduate School of Pharmaceutical Sciences , Osaka University , 1-6 Yamadaoka , Suita , Osaka 565-0871 , Japan","The Center for Advanced Medical Engineering and Informatics , Osaka University , 2-2 Yamadaoka , Suita , Osaka 565-0871 , Japan","Graduate School of Pharmaceutical Sciences, Osaka University, 1-6 Yamadaoka, Suita, Osaka 565-0871","The Center for Advanced Medical Engineering and Informatics, Osaka University, 2-2 Yamadaoka, Suita, Osaka 565-0871"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Graduate School of Pharmaceutical Sciences , Osaka University , 1-6 Yamadaoka , Suita , Osaka 565-0871 , Japan","institution_ids":["https://openalex.org/I98285908"]},{"raw_affiliation_string":"The Center for Advanced Medical Engineering and Informatics , Osaka University , 2-2 Yamadaoka , Suita , Osaka 565-0871 , Japan","institution_ids":["https://openalex.org/I98285908"]},{"raw_affiliation_string":"Graduate School of Pharmaceutical Sciences, Osaka University, 1-6 Yamadaoka, Suita, Osaka 565-0871","institution_ids":["https://openalex.org/I98285908"]},{"raw_affiliation_string":"The Center for Advanced Medical Engineering and Informatics, Osaka University, 2-2 Yamadaoka, Suita, Osaka 565-0871","institution_ids":["https://openalex.org/I98285908"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5071094094","display_name":"Kenji Ishimoto","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I98285908","display_name":"The University of Osaka","ror":"https://ror.org/035t8zc32","country_code":"JP","type":"education","lineage":["https://openalex.org/I98285908"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Kenji Ishimoto","raw_affiliation_strings":["Graduate School of Medicine , Osaka University , 2-2 Yamadaoka , Suita , Osaka 565-0871 , Japan","Graduate School of Pharmaceutical Sciences , Osaka University , 1-6 Yamadaoka , Suita , Osaka 565-0871 , Japan","Graduate School of Medicine, Osaka University, 2-2 Yamadaoka, Suita, Osaka 565-0871","Graduate School of Pharmaceutical Sciences, Osaka University, 1-6 Yamadaoka, Suita, Osaka 565-0871"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Graduate School of Medicine , Osaka University , 2-2 Yamadaoka , Suita , Osaka 565-0871 , Japan","institution_ids":["https://openalex.org/I98285908"]},{"raw_affiliation_string":"Graduate School of Pharmaceutical Sciences , Osaka University , 1-6 Yamadaoka , Suita , Osaka 565-0871 , Japan","institution_ids":["https://openalex.org/I98285908"]},{"raw_affiliation_string":"Graduate School of Medicine, Osaka University, 2-2 Yamadaoka, Suita, Osaka 565-0871","institution_ids":["https://openalex.org/I98285908"]},{"raw_affiliation_string":"Graduate School of Pharmaceutical Sciences, Osaka University, 1-6 Yamadaoka, Suita, Osaka 565-0871","institution_ids":["https://openalex.org/I98285908"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5041382010","display_name":"Takefumi Doi","orcid":"https://orcid.org/0000-0003-1092-0700","observed_orcids":["https://orcid.org/0000-0003-1092-0700"]},"institutions":[{"id":"https://openalex.org/I98285908","display_name":"The University of Osaka","ror":"https://ror.org/035t8zc32","country_code":"JP","type":"education","lineage":["https://openalex.org/I98285908"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Takefumi Doi","raw_affiliation_strings":["Graduate School of Medicine, Osaka University, 2-2 Yamadaoka, Suita, Osaka 565-0871, Japan","Graduate School of Pharmaceutical Sciences, Osaka University, 1-6 Yamadaoka, Suita, Osaka 565-0871, Japan","The Center for Advanced Medical Engineering and Informatics, Osaka University, 2-2 Yamadaoka, Suita, Osaka 565-0871, Japan","Graduate School of Medicine, Osaka University, 2-2 Yamadaoka, Suita, Osaka 565-0871","Graduate School of Pharmaceutical Sciences, Osaka University, 1-6 Yamadaoka, Suita, Osaka 565-0871","The Center for Advanced Medical Engineering and Informatics, Osaka University, 2-2 Yamadaoka, Suita, Osaka 565-0871"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Graduate School of Medicine, Osaka University, 2-2 Yamadaoka, Suita, Osaka 565-0871, Japan","institution_ids":["https://openalex.org/I98285908"]},{"raw_affiliation_string":"Graduate School of Pharmaceutical Sciences, Osaka University, 1-6 Yamadaoka, Suita, Osaka 565-0871, Japan","institution_ids":["https://openalex.org/I98285908"]},{"raw_affiliation_string":"The Center for Advanced Medical Engineering and Informatics, Osaka University, 2-2 Yamadaoka, Suita, Osaka 565-0871, Japan","institution_ids":["https://openalex.org/I98285908"]},{"raw_affiliation_string":"Graduate School of Medicine, Osaka University, 2-2 Yamadaoka, Suita, Osaka 565-0871","institution_ids":["https://openalex.org/I98285908"]},{"raw_affiliation_string":"Graduate School of Pharmaceutical Sciences, Osaka University, 1-6 Yamadaoka, Suita, Osaka 565-0871","institution_ids":["https://openalex.org/I98285908"]},{"raw_affiliation_string":"The Center for Advanced Medical Engineering and Informatics, Osaka University, 2-2 Yamadaoka, Suita, Osaka 565-0871","institution_ids":["https://openalex.org/I98285908"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5086288542"],"corresponding_institution_ids":["https://openalex.org/I98285908"],"apc_list":{"value":1630,"currency":"USD","value_usd":1630},"apc_paid":{"value":1630,"currency":"USD","value_usd":1630},"fwci":2.464,"has_fulltext":true,"cited_by_count":238,"citation_normalized_percentile":{"value":0.89326373,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":98,"max":100},"biblio":{"volume":"2008","issue":"1","first_page":"102737","last_page":"102737"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11072","display_name":"Peroxisome Proliferator-Activated Receptors","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11072","display_name":"Peroxisome Proliferator-Activated Receptors","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12465","display_name":"Cancer, Lipids, and Metabolism","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11339","display_name":"Metabolism, Diabetes, and Cancer","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/peroxisome-proliferator-activated-receptors","display_name":"peroxisome proliferator-activated receptors","score":0.9850000143051147},{"id":"https://openalex.org/keywords/pparalpha","display_name":"PPAR\u03b1","score":0.9490000009536743},{"id":"https://openalex.org/keywords/ppardelta","display_name":"PPAR\u03b4","score":0.9909999966621399},{"id":"https://openalex.org/keywords/ppargamma","display_name":"PPAR\u03b3","score":0.9589999914169312},{"id":"https://openalex.org/keywords/cancer","display_name":"cancer","score":0.7450000047683716},{"id":"https://openalex.org/keywords/tumor-growth","display_name":"tumor growth","score":0.9120000004768372},{"id":"https://openalex.org/keywords/nuclear-receptors","display_name":"nuclear receptors","score":0.8759999871253967},{"id":"https://openalex.org/keywords/transcription-factors","display_name":"transcription factors","score":0.7089999914169312},{"id":"https://openalex.org/keywords/metabolic-syndrome","display_name":"metabolic syndrome","score":0.6420000195503235},{"id":"https://openalex.org/keywords/type-2-diabetes","display_name":"type 2 diabetes","score":0.8830000162124634},{"id":"https://openalex.org/keywords/insulin-sensitivity","display_name":"insulin sensitivity","score":0.902999997138977},{"id":"https://openalex.org/keywords/adipogenic-differentiation","display_name":"adipogenesis","score":0.8050000071525574},{"id":"https://openalex.org/keywords/fatty-acid-oxidation","display_name":"fatty acid oxidation","score":0.7590000033378601},{"id":"https://openalex.org/keywords/therapeutic-target","display_name":"therapeutic target","score":0.5479999780654907}],"concepts":[{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.6780295372009277},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.6241145730018616},{"id":"https://openalex.org/C177713679","wikidata":"https://www.wikidata.org/wiki/Q679690","display_name":"Intensive care medicine","level":1,"score":0.35166478157043457},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.1976534128189087}],"mesh":[],"locations_count":6,"locations":[{"id":"doi:10.1155/2008/102737","doi":"https://doi.org/10.1155/2008/102737","is_oa":true,"landing_page_url":"https://doi.org/10.1155/2008/102737","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1155/2008/102737","source":{"id":"https://openalex.org/S71649485","display_name":"PPAR Research","issn_l":"1687-4757","issn":["1687-4757","1687-4765"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","norway-1","poland-100","russia-white-list-1"],"host_organization":"https://openalex.org/P4310319869","host_organization_name":"Hindawi Publishing Corporation","host_organization_lineage":["https://openalex.org/P4310319869","https://openalex.org/P4310320595"],"host_organization_lineage_names":["Hindawi Publishing Corporation","Wiley"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PPAR Research","raw_type":"journal-article"},{"id":"pmid:18584037","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/18584037","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PPAR research","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:2435221","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC2435221/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PPAR Res","raw_type":"Text"},{"id":"pmh:oai:CiteSeerX.psu:10.1.1.275.1499","doi":null,"is_oa":false,"landing_page_url":"http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.275.1499","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"ftp://ftp.ncbi.nlm.nih.gov/pub/pmc/25/09/PPAR_Res_2008_Jun_18_2008_102737.tar.gz","raw_type":"text"},{"id":"pmh:oai:doaj.org/article:31a61d79d22e41d5aa3898f7c5c51528","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/31a61d79d22e41d5aa3898f7c5c51528","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"PPAR Research, Vol 2008 (2008)","raw_type":"article"},{"id":"mag:2322755895","doi":null,"is_oa":false,"landing_page_url":"http://downloads.hindawi.com/journals/ppar/2008/102737.pdf","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":{"id":"doi:10.1155/2008/102737","doi":"https://doi.org/10.1155/2008/102737","is_oa":true,"landing_page_url":"https://doi.org/10.1155/2008/102737","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1155/2008/102737","source":{"id":"https://openalex.org/S71649485","display_name":"PPAR Research","issn_l":"1687-4757","issn":["1687-4757","1687-4765"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","norway-1","poland-100","russia-white-list-1"],"host_organization":"https://openalex.org/P4310319869","host_organization_name":"Hindawi Publishing Corporation","host_organization_lineage":["https://openalex.org/P4310319869","https://openalex.org/P4310320595"],"host_organization_lineage_names":["Hindawi Publishing Corporation","Wiley"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PPAR Research","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.9922999739646912}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W1967374891.pdf","grobid_xml":"https://content.openalex.org/works/W1967374891.grobid-xml"},"referenced_works_count":197,"referenced_works":["https://openalex.org/W98247596","https://openalex.org/W1416961003","https://openalex.org/W1483042740","https://openalex.org/W1486433017","https://openalex.org/W1490298078","https://openalex.org/W1511572701","https://openalex.org/W1526570055","https://openalex.org/W1548019355","https://openalex.org/W1554815317","https://openalex.org/W1586597239","https://openalex.org/W1648593433","https://openalex.org/W1672804368","https://openalex.org/W1809725106","https://openalex.org/W1820449832","https://openalex.org/W1843523988","https://openalex.org/W1892012032","https://openalex.org/W1896807099","https://openalex.org/W1916915283","https://openalex.org/W1925149569","https://openalex.org/W1948212692","https://openalex.org/W1964998210","https://openalex.org/W1966861485","https://openalex.org/W1969783942","https://openalex.org/W1970669390","https://openalex.org/W1970990727","https://openalex.org/W1971432398","https://openalex.org/W1971835418","https://openalex.org/W1972978588","https://openalex.org/W1975160900","https://openalex.org/W1975993620","https://openalex.org/W1976976178","https://openalex.org/W1977666051","https://openalex.org/W1978267311","https://openalex.org/W1978440962","https://openalex.org/W1978737330","https://openalex.org/W1979020998","https://openalex.org/W1979201752","https://openalex.org/W1979383399","https://openalex.org/W1979618971","https://openalex.org/W1979761686","https://openalex.org/W1981101682","https://openalex.org/W1982027543","https://openalex.org/W1982166284","https://openalex.org/W1982870743","https://openalex.org/W1983128420","https://openalex.org/W1985683101","https://openalex.org/W1987601141","https://openalex.org/W1988050012","https://openalex.org/W1989454102","https://openalex.org/W1989934461","https://openalex.org/W1991055758","https://openalex.org/W1991488089","https://openalex.org/W1993303817","https://openalex.org/W1993342645","https://openalex.org/W1994763926","https://openalex.org/W1995574334","https://openalex.org/W1998274672","https://openalex.org/W1998699321","https://openalex.org/W1998997365","https://openalex.org/W2001068122","https://openalex.org/W2001258296","https://openalex.org/W2001985874","https://openalex.org/W2002404925","https://openalex.org/W2002519246","https://openalex.org/W2003537519","https://openalex.org/W2003699768","https://openalex.org/W2010637857","https://openalex.org/W2012834939","https://openalex.org/W2013781186","https://openalex.org/W2014844101","https://openalex.org/W2016264364","https://openalex.org/W2017671227","https://openalex.org/W2018348035","https://openalex.org/W2020160332","https://openalex.org/W2020286683","https://openalex.org/W2022048961","https://openalex.org/W2030130710","https://openalex.org/W2030996094","https://openalex.org/W2031694725","https://openalex.org/W2033204507","https://openalex.org/W2033786341","https://openalex.org/W2036470685","https://openalex.org/W2041098455","https://openalex.org/W2041242857","https://openalex.org/W2042204452","https://openalex.org/W2044359996","https://openalex.org/W2044834383","https://openalex.org/W2045984034","https://openalex.org/W2047591801","https://openalex.org/W2047682339","https://openalex.org/W2049433363","https://openalex.org/W2049932841","https://openalex.org/W2050353671","https://openalex.org/W2051601459","https://openalex.org/W2051686420","https://openalex.org/W2052653126","https://openalex.org/W2054851194","https://openalex.org/W2057918116","https://openalex.org/W2059272333","https://openalex.org/W2059813946","https://openalex.org/W2061809006","https://openalex.org/W2062159267","https://openalex.org/W2064974844","https://openalex.org/W2065532093","https://openalex.org/W2065725049","https://openalex.org/W2066092624","https://openalex.org/W2070123035","https://openalex.org/W2070299412","https://openalex.org/W2071373198","https://openalex.org/W2072093204","https://openalex.org/W2074058488","https://openalex.org/W2075245841","https://openalex.org/W2077212752","https://openalex.org/W2081577661","https://openalex.org/W2081992161","https://openalex.org/W2082597621","https://openalex.org/W2083362070","https://openalex.org/W2084774843","https://openalex.org/W2087487881","https://openalex.org/W2087744847","https://openalex.org/W2088144835","https://openalex.org/W2088233968","https://openalex.org/W2088905899","https://openalex.org/W2089586991","https://openalex.org/W2090553336","https://openalex.org/W2091124516","https://openalex.org/W2091321756","https://openalex.org/W2092040814","https://openalex.org/W2093531978","https://openalex.org/W2094317359","https://openalex.org/W2094795797","https://openalex.org/W2094961418","https://openalex.org/W2097357124","https://openalex.org/W2097679250","https://openalex.org/W2099747965","https://openalex.org/W2100820757","https://openalex.org/W2102998952","https://openalex.org/W2104996921","https://openalex.org/W2107037828","https://openalex.org/W2111016870","https://openalex.org/W2112709904","https://openalex.org/W2113868760","https://openalex.org/W2114286828","https://openalex.org/W2114553620","https://openalex.org/W2114597279","https://openalex.org/W2115182180","https://openalex.org/W2115248871","https://openalex.org/W2116103211","https://openalex.org/W2120736359","https://openalex.org/W2120865762","https://openalex.org/W2121670409","https://openalex.org/W2124317382","https://openalex.org/W2124630453","https://openalex.org/W2125093719","https://openalex.org/W2125141706","https://openalex.org/W2126853519","https://openalex.org/W2129307092","https://openalex.org/W2131037449","https://openalex.org/W2139002144","https://openalex.org/W2139370730","https://openalex.org/W2139692118","https://openalex.org/W2140038597","https://openalex.org/W2140980131","https://openalex.org/W2141064285","https://openalex.org/W2141726002","https://openalex.org/W2143637476","https://openalex.org/W2143974057","https://openalex.org/W2145168681","https://openalex.org/W2146597835","https://openalex.org/W2146812359","https://openalex.org/W2147326561","https://openalex.org/W2148709408","https://openalex.org/W2149182758","https://openalex.org/W2151663349","https://openalex.org/W2154669801","https://openalex.org/W2154672973","https://openalex.org/W2157433311","https://openalex.org/W2158050590","https://openalex.org/W2158100456","https://openalex.org/W2161276143","https://openalex.org/W2162178319","https://openalex.org/W2163244708","https://openalex.org/W2163431844","https://openalex.org/W2164015929","https://openalex.org/W2164194749","https://openalex.org/W2164721789","https://openalex.org/W2168300082","https://openalex.org/W2169224393","https://openalex.org/W2170985017","https://openalex.org/W2171844209","https://openalex.org/W2172256092","https://openalex.org/W2601704071","https://openalex.org/W4205765598","https://openalex.org/W4245647015","https://openalex.org/W4291113916","https://openalex.org/W7073620198","https://openalex.org/W7096614888"],"related_works":["https://openalex.org/W7097094911","https://openalex.org/W3021645836","https://openalex.org/W2469408665","https://openalex.org/W3096289954","https://openalex.org/W2741713758","https://openalex.org/W2293248093","https://openalex.org/W2008867227","https://openalex.org/W1503589126","https://openalex.org/W4399973953","https://openalex.org/W2898368038"],"abstract_inverted_index":{"Peroxisome":[0],"proliferator-activated":[1],"receptors":[2],"(PPARs)":[3],"are":[4,113],"ligand-activated":[5],"transcription":[6],"factors":[7],"that":[8],"belong":[9],"to":[10,34],"the":[11,21,69,96,117,131,140],"nuclear":[12],"hormone":[13],"receptor":[14],"superfamily.":[15],"PPARalpha":[16,29],"is":[17,50,54,75,90],"mainly":[18],"expressed":[19,51,76],"in":[20,40,56,78,86,92,130,144],"liver,":[22],"where":[23],"it":[24],"activates":[25],"fatty":[26,57],"acid":[27,58],"catabolism.":[28],"activators":[30,64],"have":[31,65],"been":[32,66],"used":[33],"treat":[35],"dyslipidemia,":[36],"causing":[37],"a":[38,83,103,128],"reduction":[39],"plasma":[41],"triglyceride":[42],"and":[43,53,60,81,101],"elevation":[44],"of":[45,71,98,107,119,133,142],"high-density":[46],"lipoprotein":[47],"cholesterol.":[48],"PPARdelta":[49,63],"ubiquitously":[52],"implicated":[55],"oxidation":[59],"keratinocyte":[61],"differentiation.":[62,88],"proposed":[67],"for":[68,116],"treatment":[70],"metabolic":[72,122],"disease.":[73],"PPARgamma2":[74],"exclusively":[77],"adipose":[79],"tissue":[80],"plays":[82],"pivotal":[84],"role":[85,129],"adipocyte":[87],"PPARgamma":[89],"involved":[91],"glucose":[93],"metabolism":[94],"through":[95],"improvement":[97],"insulin":[99],"sensitivity":[100],"represents":[102],"potential":[104],"therapeutic":[105],"target":[106],"type":[108],"2":[109],"diabetes.":[110],"Thus":[111],"PPARs":[112,125,143],"molecular":[114],"targets":[115],"development":[118],"drugs":[120],"treating":[121],"syndrome.":[123],"However,":[124],"also":[126],"play":[127],"regulation":[132],"cancer":[134],"cell":[135],"growth.":[136,146],"Here,":[137],"we":[138],"review":[139],"function":[141],"tumor":[145]},"counts_by_year":[{"year":2026,"cited_by_count":6},{"year":2025,"cited_by_count":7},{"year":2024,"cited_by_count":9},{"year":2023,"cited_by_count":13},{"year":2022,"cited_by_count":17},{"year":2021,"cited_by_count":21},{"year":2020,"cited_by_count":21},{"year":2019,"cited_by_count":20},{"year":2018,"cited_by_count":23},{"year":2017,"cited_by_count":14},{"year":2016,"cited_by_count":14},{"year":2015,"cited_by_count":10},{"year":2014,"cited_by_count":15},{"year":2013,"cited_by_count":14},{"year":2012,"cited_by_count":12}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2016-06-24T00:00:00"}
