{"id":"https://openalex.org/W1967287652","doi":"https://doi.org/10.1007/bf02553940","title":"Steroid receptors and the distribution of IR-carcinoembryonic antigen in colonic cancer","display_name":"Steroid receptors and the distribution of IR-carcinoembryonic antigen in colonic cancer","publication_year":1984,"publication_date":"1984-12-01","ids":{"openalex":"https://openalex.org/W1967287652","doi":"https://doi.org/10.1007/bf02553940","mag":"1967287652","pmid":"https://pubmed.ncbi.nlm.nih.gov/6499618"},"language":"en","primary_location":{"id":"doi:10.1007/bf02553940","doi":"https://doi.org/10.1007/bf02553940","is_oa":false,"landing_page_url":"https://doi.org/10.1007/bf02553940","pdf_url":null,"source":{"id":"https://openalex.org/S170496595","display_name":"Diseases of the Colon & Rectum","issn_l":"0012-3706","issn":["0012-3706","1530-0358"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Diseases of the Colon & Rectum","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5089598411","display_name":"E Odagiri","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210136522","display_name":"Tokyo Women's Medical University","ror":"https://ror.org/03kjjhe36","country_code":"JP","type":"education","lineage":["https://openalex.org/I4210136522"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Emi Odagiri","raw_affiliation_strings":["Department of Radioassay, Tokyo Women's Medical College, 10 Kawadacho, Ichigaya, Shinjuku-ku, Tokyo, Japan","Department of Radioassay, Tokyo Women's Medical College, Tokyo, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radioassay, Tokyo Women's Medical College, 10 Kawadacho, Ichigaya, Shinjuku-ku, Tokyo, Japan","institution_ids":["https://openalex.org/I4210136522"]},{"raw_affiliation_string":"Department of Radioassay, Tokyo Women's Medical College, Tokyo, Japan","institution_ids":["https://openalex.org/I4210136522"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5043225149","display_name":"K Jibiki","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210136522","display_name":"Tokyo Women's Medical University","ror":"https://ror.org/03kjjhe36","country_code":"JP","type":"education","lineage":["https://openalex.org/I4210136522"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Kazuko Jibiki","raw_affiliation_strings":["Department of Radioassay, Tokyo Women's Medical College, 10 Kawadacho, Ichigaya, Shinjuku-ku, Tokyo, Japan","Department of Radioassay, Tokyo Women's Medical College, Tokyo, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radioassay, Tokyo Women's Medical College, 10 Kawadacho, Ichigaya, Shinjuku-ku, Tokyo, Japan","institution_ids":["https://openalex.org/I4210136522"]},{"raw_affiliation_string":"Department of Radioassay, Tokyo Women's Medical College, Tokyo, Japan","institution_ids":["https://openalex.org/I4210136522"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5027193503","display_name":"Reiko Demura","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210136522","display_name":"Tokyo Women's Medical University","ror":"https://ror.org/03kjjhe36","country_code":"JP","type":"education","lineage":["https://openalex.org/I4210136522"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Reiko Demura","raw_affiliation_strings":["Department of Radioassay, Tokyo Women's Medical College, 10 Kawadacho, Ichigaya, Shinjuku-ku, Tokyo, Japan","Department of Radioassay, Tokyo Women's Medical College, Tokyo, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radioassay, Tokyo Women's Medical College, 10 Kawadacho, Ichigaya, Shinjuku-ku, Tokyo, Japan","institution_ids":["https://openalex.org/I4210136522"]},{"raw_affiliation_string":"Department of Radioassay, Tokyo Women's Medical College, Tokyo, Japan","institution_ids":["https://openalex.org/I4210136522"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5019588261","display_name":"Hatsue Shinozaki","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210136522","display_name":"Tokyo Women's Medical University","ror":"https://ror.org/03kjjhe36","country_code":"JP","type":"education","lineage":["https://openalex.org/I4210136522"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Hatsue Shinozaki","raw_affiliation_strings":["Department of Radioassay, Tokyo Women's Medical College, 10 Kawadacho, Ichigaya, Shinjuku-ku, Tokyo, Japan","Department of Radioassay, Tokyo Women's Medical College, Tokyo, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radioassay, Tokyo Women's Medical College, 10 Kawadacho, Ichigaya, Shinjuku-ku, Tokyo, Japan","institution_ids":["https://openalex.org/I4210136522"]},{"raw_affiliation_string":"Department of Radioassay, Tokyo Women's Medical College, Tokyo, Japan","institution_ids":["https://openalex.org/I4210136522"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111453787","display_name":"Saeko Nakamura","orcid":"https://orcid.org/0009-0007-4032-1860","observed_orcids":["https://orcid.org/0009-0007-4032-1860"]},"institutions":[{"id":"https://openalex.org/I4210136522","display_name":"Tokyo Women's Medical University","ror":"https://ror.org/03kjjhe36","country_code":"JP","type":"education","lineage":["https://openalex.org/I4210136522"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Saeko Nakamura","raw_affiliation_strings":["Department of Radioassay, Tokyo Women's Medical College, 10 Kawadacho, Ichigaya, Shinjuku-ku, Tokyo, Japan","Department of Radioassay, Tokyo Women's Medical College, Tokyo, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radioassay, Tokyo Women's Medical College, 10 Kawadacho, Ichigaya, Shinjuku-ku, Tokyo, Japan","institution_ids":["https://openalex.org/I4210136522"]},{"raw_affiliation_string":"Department of Radioassay, Tokyo Women's Medical College, Tokyo, Japan","institution_ids":["https://openalex.org/I4210136522"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5030293363","display_name":"Hiroshi Demura","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210136522","display_name":"Tokyo Women's Medical University","ror":"https://ror.org/03kjjhe36","country_code":"JP","type":"education","lineage":["https://openalex.org/I4210136522"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Hiroshi Demura","raw_affiliation_strings":["Department of Radioassay, Tokyo Women's Medical College, 10 Kawadacho, Ichigaya, Shinjuku-ku, Tokyo, Japan","Department of Radioassay, Tokyo Women's Medical College, Tokyo, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radioassay, Tokyo Women's Medical College, 10 Kawadacho, Ichigaya, Shinjuku-ku, Tokyo, Japan","institution_ids":["https://openalex.org/I4210136522"]},{"raw_affiliation_string":"Department of Radioassay, Tokyo Women's Medical College, Tokyo, Japan","institution_ids":["https://openalex.org/I4210136522"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5101764169","display_name":"Hirotaka Suzuki","orcid":"https://orcid.org/0000-0003-0056-1986","observed_orcids":["https://orcid.org/0000-0003-0056-1986"]},"institutions":[{"id":"https://openalex.org/I4210136522","display_name":"Tokyo Women's Medical University","ror":"https://ror.org/03kjjhe36","country_code":"JP","type":"education","lineage":["https://openalex.org/I4210136522"]},{"id":"https://openalex.org/I4405286151","display_name":"Institute of Gastroenterology, Tokyo Women's Medical University","ror":"https://ror.org/0191nbh46","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210098959","https://openalex.org/I4405286151"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Hirotaka Suzuki","raw_affiliation_strings":["Institute of Gastroenterology, Tokyo Women's Medical College, Tokyo, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Gastroenterology, Tokyo Women's Medical College, Tokyo, Japan","institution_ids":["https://openalex.org/I4210136522","https://openalex.org/I4405286151"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.847,"has_fulltext":false,"cited_by_count":20,"citation_normalized_percentile":{"value":0.69858395,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":93},"biblio":{"volume":"27","issue":"12","first_page":"787","last_page":"791"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10756","display_name":"Estrogen and related hormone effects","score":0.7939000129699707,"subfield":{"id":"https://openalex.org/subfields/1310","display_name":"Endocrinology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10756","display_name":"Estrogen and related hormone effects","score":0.7939000129699707,"subfield":{"id":"https://openalex.org/subfields/1310","display_name":"Endocrinology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10335","display_name":"Colorectal Cancer Surgical Treatments","score":0.042399998754262924,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11067","display_name":"Colorectal Cancer Treatments and Studies","score":0.02199999988079071,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/colon-cancer","display_name":"colon cancer","score":0.9570000171661377},{"id":"https://openalex.org/keywords/carcinoembryonic-antigen","display_name":"carcinoembryonic antigen","score":0.8799999952316284},{"id":"https://openalex.org/keywords/estrogen-receptor","display_name":"estrogen receptor","score":0.7670000195503235},{"id":"https://openalex.org/keywords/progesterone-receptor","display_name":"progesterone receptor","score":1.0},{"id":"https://openalex.org/keywords/steroid-hormone-receptors","display_name":"steroid hormone receptors","score":0.871999979019165},{"id":"https://openalex.org/keywords/postmenopausal-women","display_name":"postmenopausal women","score":0.8629999756813049},{"id":"https://openalex.org/keywords/tumor-stage","display_name":"tumor stage","score":0.3659999966621399}],"concepts":[{"id":"https://openalex.org/C2777387746","wikidata":"https://www.wikidata.org/wiki/Q769706","display_name":"Carcinoembryonic antigen","level":3,"score":0.9022146463394165},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.7891581654548645},{"id":"https://openalex.org/C176685330","wikidata":"https://www.wikidata.org/wiki/Q857638","display_name":"Radioimmunoassay","level":2,"score":0.6054102182388306},{"id":"https://openalex.org/C526805850","wikidata":"https://www.wikidata.org/wiki/Q188874","display_name":"Colorectal cancer","level":3,"score":0.5935627818107605},{"id":"https://openalex.org/C84606932","wikidata":"https://www.wikidata.org/wiki/Q416496","display_name":"Estrogen receptor","level":4,"score":0.5473626852035522},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.5423068404197693},{"id":"https://openalex.org/C204232928","wikidata":"https://www.wikidata.org/wiki/Q899285","display_name":"Immunohistochemistry","level":2,"score":0.5344011187553406},{"id":"https://openalex.org/C2780140570","wikidata":"https://www.wikidata.org/wiki/Q3545481","display_name":"Surgical oncology","level":2,"score":0.530546247959137},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.5027501583099365},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.4979085922241211},{"id":"https://openalex.org/C110121322","wikidata":"https://www.wikidata.org/wiki/Q865811","display_name":"Distribution (mathematics)","level":2,"score":0.46927610039711},{"id":"https://openalex.org/C2780902042","wikidata":"https://www.wikidata.org/wiki/Q177911","display_name":"Steroid","level":3,"score":0.4590936601161957},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.4536055028438568},{"id":"https://openalex.org/C2777164284","wikidata":"https://www.wikidata.org/wiki/Q277954","display_name":"Estrogen","level":2,"score":0.4345465898513794},{"id":"https://openalex.org/C90924648","wikidata":"https://www.wikidata.org/wiki/Q120569","display_name":"Gastroenterology","level":1,"score":0.41712355613708496},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.39123377203941345},{"id":"https://openalex.org/C530470458","wikidata":"https://www.wikidata.org/wiki/Q128581","display_name":"Breast cancer","level":3,"score":0.31794846057891846},{"id":"https://openalex.org/C71315377","wikidata":"https://www.wikidata.org/wiki/Q11364","display_name":"Hormone","level":2,"score":0.31374824047088623},{"id":"https://openalex.org/C134306372","wikidata":"https://www.wikidata.org/wiki/Q7754","display_name":"Mathematical analysis","level":1,"score":0.0},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002272","descriptor_name":"Carcinoembryonic Antigen","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":true},{"descriptor_ui":"D002272","descriptor_name":"Carcinoembryonic Antigen","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D002430","descriptor_name":"Cecal Neoplasms","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D003110","descriptor_name":"Colonic Neoplasms","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D003110","descriptor_name":"Colonic Neoplasms","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007414","descriptor_name":"Intestinal Neoplasms","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011987","descriptor_name":"Receptors, Steroid","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D012004","descriptor_name":"Rectal Neoplasms","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D012811","descriptor_name":"Sigmoid Neoplasms","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1007/bf02553940","doi":"https://doi.org/10.1007/bf02553940","is_oa":false,"landing_page_url":"https://doi.org/10.1007/bf02553940","pdf_url":null,"source":{"id":"https://openalex.org/S170496595","display_name":"Diseases of the Colon & Rectum","issn_l":"0012-3706","issn":["0012-3706","1530-0358"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Diseases of the Colon & Rectum","raw_type":"journal-article"},{"id":"pmid:6499618","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/6499618","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Diseases of the colon and rectum","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.9763000011444092,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":18,"referenced_works":["https://openalex.org/W1634658554","https://openalex.org/W1775749144","https://openalex.org/W1811094195","https://openalex.org/W1955011099","https://openalex.org/W1970393694","https://openalex.org/W1972415284","https://openalex.org/W1996753936","https://openalex.org/W2002816752","https://openalex.org/W2011798568","https://openalex.org/W2025348614","https://openalex.org/W2054966438","https://openalex.org/W2059280823","https://openalex.org/W2079808933","https://openalex.org/W2158970305","https://openalex.org/W2400073331","https://openalex.org/W2412975599","https://openalex.org/W4285719527","https://openalex.org/W4300033449"],"related_works":["https://openalex.org/W2001669571","https://openalex.org/W1994617622","https://openalex.org/W4367720810","https://openalex.org/W2135043107","https://openalex.org/W2414302691","https://openalex.org/W51673901","https://openalex.org/W207330209","https://openalex.org/W1480563095","https://openalex.org/W2006008216","https://openalex.org/W2260265607"],"abstract_inverted_index":{"Twenty-five":[0],"colonic":[1,44],"cancer":[2,76],"tissues":[3],"were":[4,27,53,58,102],"studied":[5],"for":[6],"the":[7,17,47,80,89,96,99],"presence":[8],"of":[9,19,40,56,71,98,111],"estrogen":[10],"and":[11,16,25,34,115,118],"progesterone":[12],"receptors":[13],"(ER,":[14],"PR)":[15],"distribution":[18,110],"immunoreactive":[20],"carcinoembryonic":[21],"antigen":[22],"(IR-CEA).":[23],"ER":[24],"PR":[26],"determined":[28],"in":[29,79,88,113],"6":[30],"(24":[31],"per":[32,37],"cent)":[33],"3":[35],"(12":[36],"cent),":[38],"respectively,":[39],"25":[41],"patients":[42,49],"with":[43,50,66],"cancer.":[45],"Of":[46],"six":[48],"ER,":[51],"five":[52],"females,":[54],"four":[55],"whom":[57],"postmenopausal.":[59],"Steroid":[60],"receptors,":[61],"however,":[62,95],"had":[63],"no":[64],"correlation":[65],"age,":[67],"tumor":[68],"localization,":[69],"stage":[70],"disease":[72],"or":[73],"IR-CEA.":[74],"In":[75,92],"tissue,":[77],"IR-CEA":[78,112],"cytosol":[81],"fraction":[82],"was":[83],"higher":[84],"than":[85],"that":[86],"found":[87],"membrane":[90],"fraction.":[91],"normal":[93,116],"colon,":[94,117],"concentrations":[97],"two":[100],"fractions":[101],"reversed.":[103],"Immunohistochemical":[104],"findings":[105,123],"have":[106],"shown":[107],"a":[108],"different":[109],"cancerous":[114],"our":[119],"results":[120],"demonstrated":[121],"similar":[122],"by":[124],"using":[125],"radioimmunoassay":[126],"(RIA).":[127]},"counts_by_year":[{"year":2019,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}