{"id":"https://openalex.org/W1967284168","doi":"https://doi.org/10.1093/nar/gks820","title":"Promoters active in interphase are bookmarked during mitosis by ubiquitination","display_name":"Promoters active in interphase are bookmarked during mitosis by ubiquitination","publication_year":2012,"publication_date":"2012-08-30","ids":{"openalex":"https://openalex.org/W1967284168","doi":"https://doi.org/10.1093/nar/gks820","mag":"1967284168","pmid":"https://pubmed.ncbi.nlm.nih.gov/22941662","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/3488253"},"language":"en","primary_location":{"id":"doi:10.1093/nar/gks820","doi":"https://doi.org/10.1093/nar/gks820","is_oa":true,"landing_page_url":"https://doi.org/10.1093/nar/gks820","pdf_url":"https://academic.oup.com/nar/article-pdf/40/20/10187/16961486/gks820.pdf","source":{"id":"https://openalex.org/S134668137","display_name":"Nucleic Acids Research","issn_l":"0305-1048","issn":["0305-1048","1362-4954","1362-4962"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","oarl","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nucleic Acids Research","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://academic.oup.com/nar/article-pdf/40/20/10187/16961486/gks820.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5061882560","display_name":"Mansi Arora","orcid":"https://orcid.org/0009-0009-8832-4926","observed_orcids":["https://orcid.org/0009-0009-8832-4926"]},"institutions":[{"id":"https://openalex.org/I2799885155","display_name":"The Ohio State University Comprehensive Cancer Center \u2013 Arthur G. James Cancer Hospital and Richard J. Solove Research Institute","ror":"https://ror.org/028t46f04","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799885155","https://openalex.org/I2802841970"]},{"id":"https://openalex.org/I52357470","display_name":"The Ohio State University","ror":"https://ror.org/00rs6vg23","country_code":"US","type":"education","lineage":["https://openalex.org/I52357470"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Mansi Arora","raw_affiliation_strings":["Department of Biomedical Informatics and the Ohio State University Comprehensive Cancer Center, The Ohio State University, Columbus, OH 43210, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biomedical Informatics and the Ohio State University Comprehensive Cancer Center, The Ohio State University, Columbus, OH 43210, USA","institution_ids":["https://openalex.org/I2799885155","https://openalex.org/I52357470"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100436623","display_name":"Jie Zhang","orcid":"https://orcid.org/0000-0001-6939-7905","observed_orcids":["https://orcid.org/0000-0001-6939-7905"]},"institutions":[{"id":"https://openalex.org/I2799885155","display_name":"The Ohio State University Comprehensive Cancer Center \u2013 Arthur G. James Cancer Hospital and Richard J. Solove Research Institute","ror":"https://ror.org/028t46f04","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799885155","https://openalex.org/I2802841970"]},{"id":"https://openalex.org/I52357470","display_name":"The Ohio State University","ror":"https://ror.org/00rs6vg23","country_code":"US","type":"education","lineage":["https://openalex.org/I52357470"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jie Zhang","raw_affiliation_strings":["Department of Biomedical Informatics and the Ohio State University Comprehensive Cancer Center, The Ohio State University, Columbus, OH 43210, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biomedical Informatics and the Ohio State University Comprehensive Cancer Center, The Ohio State University, Columbus, OH 43210, USA","institution_ids":["https://openalex.org/I2799885155","https://openalex.org/I52357470"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5031880482","display_name":"George F. Heine","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2799885155","display_name":"The Ohio State University Comprehensive Cancer Center \u2013 Arthur G. James Cancer Hospital and Richard J. Solove Research Institute","ror":"https://ror.org/028t46f04","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799885155","https://openalex.org/I2802841970"]},{"id":"https://openalex.org/I52357470","display_name":"The Ohio State University","ror":"https://ror.org/00rs6vg23","country_code":"US","type":"education","lineage":["https://openalex.org/I52357470"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"George F. Heine","raw_affiliation_strings":["Department of Biomedical Informatics and the Ohio State University Comprehensive Cancer Center, The Ohio State University, Columbus, OH 43210, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biomedical Informatics and the Ohio State University Comprehensive Cancer Center, The Ohio State University, Columbus, OH 43210, USA","institution_ids":["https://openalex.org/I2799885155","https://openalex.org/I52357470"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5080628262","display_name":"Gulcin H. Ozer","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2799885155","display_name":"The Ohio State University Comprehensive Cancer Center \u2013 Arthur G. James Cancer Hospital and Richard J. Solove Research Institute","ror":"https://ror.org/028t46f04","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799885155","https://openalex.org/I2802841970"]},{"id":"https://openalex.org/I52357470","display_name":"The Ohio State University","ror":"https://ror.org/00rs6vg23","country_code":"US","type":"education","lineage":["https://openalex.org/I52357470"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Gulcin Ozer","raw_affiliation_strings":["Department of Biomedical Informatics and the Ohio State University Comprehensive Cancer Center, The Ohio State University, Columbus, OH 43210, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biomedical Informatics and the Ohio State University Comprehensive Cancer Center, The Ohio State University, Columbus, OH 43210, USA","institution_ids":["https://openalex.org/I2799885155","https://openalex.org/I52357470"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5051865966","display_name":"Hui-wen Liu","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2799885155","display_name":"The Ohio State University Comprehensive Cancer Center \u2013 Arthur G. James Cancer Hospital and Richard J. Solove Research Institute","ror":"https://ror.org/028t46f04","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799885155","https://openalex.org/I2802841970"]},{"id":"https://openalex.org/I52357470","display_name":"The Ohio State University","ror":"https://ror.org/00rs6vg23","country_code":"US","type":"education","lineage":["https://openalex.org/I52357470"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Hui-wen Liu","raw_affiliation_strings":["Department of Biomedical Informatics and the Ohio State University Comprehensive Cancer Center, The Ohio State University, Columbus, OH 43210, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biomedical Informatics and the Ohio State University Comprehensive Cancer Center, The Ohio State University, Columbus, OH 43210, USA","institution_ids":["https://openalex.org/I2799885155","https://openalex.org/I52357470"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5057366605","display_name":"Kun Huang","orcid":"https://orcid.org/0000-0002-8530-370X","observed_orcids":["https://orcid.org/0000-0002-8530-370X","https://orcid.org/0000-0001-8550-4571","https://orcid.org/0000-0003-0071-7522","https://orcid.org/0000-0003-0797-8338","https://orcid.org/0000-0002-9400-9799"]},"institutions":[{"id":"https://openalex.org/I2799885155","display_name":"The Ohio State University Comprehensive Cancer Center \u2013 Arthur G. James Cancer Hospital and Richard J. Solove Research Institute","ror":"https://ror.org/028t46f04","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799885155","https://openalex.org/I2802841970"]},{"id":"https://openalex.org/I52357470","display_name":"The Ohio State University","ror":"https://ror.org/00rs6vg23","country_code":"US","type":"education","lineage":["https://openalex.org/I52357470"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Kun Huang","raw_affiliation_strings":["Department of Biomedical Informatics and the Ohio State University Comprehensive Cancer Center, The Ohio State University, Columbus, OH 43210, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biomedical Informatics and the Ohio State University Comprehensive Cancer Center, The Ohio State University, Columbus, OH 43210, USA","institution_ids":["https://openalex.org/I2799885155","https://openalex.org/I52357470"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5023251641","display_name":"Jeffrey D. Parvin","orcid":"https://orcid.org/0000-0001-5616-1928","observed_orcids":["https://orcid.org/0000-0001-5616-1928"]},"institutions":[{"id":"https://openalex.org/I2799885155","display_name":"The Ohio State University Comprehensive Cancer Center \u2013 Arthur G. James Cancer Hospital and Richard J. Solove Research Institute","ror":"https://ror.org/028t46f04","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799885155","https://openalex.org/I2802841970"]},{"id":"https://openalex.org/I52357470","display_name":"The Ohio State University","ror":"https://ror.org/00rs6vg23","country_code":"US","type":"education","lineage":["https://openalex.org/I52357470"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Jeffrey D. Parvin","raw_affiliation_strings":["Department of Biomedical Informatics and the Ohio State University Comprehensive Cancer Center, The Ohio State University, Columbus, OH 43210, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biomedical Informatics and the Ohio State University Comprehensive Cancer Center, The Ohio State University, Columbus, OH 43210, USA","institution_ids":["https://openalex.org/I2799885155","https://openalex.org/I52357470"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5023251641"],"corresponding_institution_ids":["https://openalex.org/I2799885155","https://openalex.org/I52357470"],"apc_list":{"value":3992,"currency":"USD","value_usd":3992},"apc_paid":{"value":3992,"currency":"USD","value_usd":3992},"fwci":0.3853,"has_fulltext":false,"cited_by_count":9,"citation_normalized_percentile":{"value":0.56804684,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":97},"biblio":{"volume":"40","issue":"20","first_page":"10187","last_page":"10202"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10222","display_name":"Genomics and Chromatin Dynamics","score":0.9926999807357788,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10222","display_name":"Genomics and Chromatin Dynamics","score":0.9926999807357788,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10269","display_name":"Epigenetics and DNA Methylation","score":0.0027000000700354576,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11041","display_name":"Ubiquitin and proteasome pathways","score":0.002099999925121665,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/ubiquitination","display_name":"ubiquitination","score":0.7519999742507935},{"id":"https://openalex.org/keywords/chromatin-modification","display_name":"chromatin modification","score":0.6629999876022339},{"id":"https://openalex.org/keywords/mitosis","display_name":"mitosis","score":0.8759999871253967},{"id":"https://openalex.org/keywords/interphase","display_name":"interphase","score":0.8130000233650208},{"id":"https://openalex.org/keywords/rnf20","display_name":"RNF20","score":0.7799999713897705},{"id":"https://openalex.org/keywords/histone-modifications","display_name":"histone modifications","score":0.6710000038146973},{"id":"https://openalex.org/keywords/h3k4me3","display_name":"H3K4me3","score":0.9890000224113464},{"id":"https://openalex.org/keywords/h3k36me3","display_name":"H3K36me3","score":1.0},{"id":"https://openalex.org/keywords/h3k27me3","display_name":"H3K27me3","score":0.9419999718666077},{"id":"https://openalex.org/keywords/transcriptional-reactivation","display_name":"transcriptional reactivation","score":0.8659999966621399},{"id":"https://openalex.org/keywords/cell-cycle","display_name":"cell cycle","score":0.6639999747276306},{"id":"https://openalex.org/keywords/gene-expression","display_name":"gene expression","score":0.3619999885559082}],"concepts":[{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.8014979362487793},{"id":"https://openalex.org/C93304396","wikidata":"https://www.wikidata.org/wiki/Q14763008","display_name":"Mitosis","level":2,"score":0.790347695350647},{"id":"https://openalex.org/C83640560","wikidata":"https://www.wikidata.org/wiki/Q180951","display_name":"Chromatin","level":3,"score":0.7857391834259033},{"id":"https://openalex.org/C29452124","wikidata":"https://www.wikidata.org/wiki/Q835950","display_name":"Interphase","level":2,"score":0.6244856715202332},{"id":"https://openalex.org/C178108356","wikidata":"https://www.wikidata.org/wiki/Q7240230","display_name":"Premature chromosome condensation","level":4,"score":0.6083455085754395},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.6034006476402283},{"id":"https://openalex.org/C64927066","wikidata":"https://www.wikidata.org/wiki/Q36293","display_name":"Histone","level":3,"score":0.522125780582428},{"id":"https://openalex.org/C101762097","wikidata":"https://www.wikidata.org/wiki/Q224093","display_name":"Promoter","level":4,"score":0.48514899611473083},{"id":"https://openalex.org/C25602115","wikidata":"https://www.wikidata.org/wiki/Q407111","display_name":"Ubiquitin","level":3,"score":0.4587469696998596},{"id":"https://openalex.org/C45413362","wikidata":"https://www.wikidata.org/wiki/Q6013254","display_name":"Prophase","level":4,"score":0.4569123685359955},{"id":"https://openalex.org/C153911025","wikidata":"https://www.wikidata.org/wiki/Q7202","display_name":"Molecular biology","level":1,"score":0.42661482095718384},{"id":"https://openalex.org/C29537977","wikidata":"https://www.wikidata.org/wiki/Q188941","display_name":"Cell cycle","level":3,"score":0.41077589988708496},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.285702109336853},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.25201064348220825},{"id":"https://openalex.org/C150194340","wikidata":"https://www.wikidata.org/wiki/Q26972","display_name":"Gene expression","level":3,"score":0.18646371364593506},{"id":"https://openalex.org/C148196450","wikidata":"https://www.wikidata.org/wiki/Q21100485","display_name":"Meiosis","level":3,"score":0.052906334400177}],"mesh":[{"descriptor_ui":"D002453","descriptor_name":"Cell Cycle","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D002843","descriptor_name":"Chromatin","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D006367","descriptor_name":"HeLa Cells","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006657","descriptor_name":"Histones","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007399","descriptor_name":"Interphase","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D008938","descriptor_name":"Mitosis","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D011401","descriptor_name":"Promoter Regions, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D014158","descriptor_name":"Transcription, Genetic","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D016678","descriptor_name":"Genome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019384","descriptor_name":"Nucleic Acid Synthesis Inhibitors","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D025801","descriptor_name":"Ubiquitin","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D044767","descriptor_name":"Ubiquitin-Protein Ligases","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D054875","descriptor_name":"Ubiquitination","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true}],"locations_count":5,"locations":[{"id":"doi:10.1093/nar/gks820","doi":"https://doi.org/10.1093/nar/gks820","is_oa":true,"landing_page_url":"https://doi.org/10.1093/nar/gks820","pdf_url":"https://academic.oup.com/nar/article-pdf/40/20/10187/16961486/gks820.pdf","source":{"id":"https://openalex.org/S134668137","display_name":"Nucleic Acids Research","issn_l":"0305-1048","issn":["0305-1048","1362-4954","1362-4962"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","oarl","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nucleic Acids Research","raw_type":"journal-article"},{"id":"pmh:oai:europepmc.org:2488991","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3488253","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:3488253","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3488253","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nucleic Acids Res","raw_type":"Text"},{"id":"pmid:22941662","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/22941662","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nucleic acids research","raw_type":"Journal Article"},{"id":"pmh:oai:open-archive.highwire.org:nar:40/20/10187","doi":null,"is_oa":false,"landing_page_url":"http://nar.oxfordjournals.org/cgi/content/short/40/20/10187","pdf_url":null,"source":{"id":"https://openalex.org/S4406923041","display_name":"HighWire Press Open Archive","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"TEXT"}],"best_oa_location":{"id":"doi:10.1093/nar/gks820","doi":"https://doi.org/10.1093/nar/gks820","is_oa":true,"landing_page_url":"https://doi.org/10.1093/nar/gks820","pdf_url":"https://academic.oup.com/nar/article-pdf/40/20/10187/16961486/gks820.pdf","source":{"id":"https://openalex.org/S134668137","display_name":"Nucleic Acids Research","issn_l":"0305-1048","issn":["0305-1048","1362-4954","1362-4962"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","oarl","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nucleic Acids Research","raw_type":"journal-article"},"sustainable_development_goals":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G1510075364","display_name":null,"funder_award_id":"CA130302","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"},{"id":"https://openalex.org/G2036856473","display_name":null,"funder_award_id":"CA141090","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"},{"id":"https://openalex.org/G4100139","display_name":"Understanding the role of BRCA1 in response to DNA damage","funder_award_id":"5f32ca130302-02","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G6900037400","display_name":null,"funder_award_id":"CA111480","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"},{"id":"https://openalex.org/G8208889158","display_name":"Centrosomes and BRCA1","funder_award_id":"R01CA111480","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"},{"id":"https://openalex.org/G835679153","display_name":"Informatics methods for identifying breast cancer control genes and proteins","funder_award_id":"R01CA141090","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"},{"id":"https://openalex.org/G9000887552","display_name":"Cancer Center Support Grant","funder_award_id":"P30CA016058","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"}],"funders":[{"id":"https://openalex.org/F4320309374","display_name":"Ohio State University","ror":"https://ror.org/00rs6vg23"},{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337351","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81"}],"has_content":{"grobid_xml":false,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W1967284168.pdf"},"referenced_works_count":61,"referenced_works":["https://openalex.org/W415599051","https://openalex.org/W1495218540","https://openalex.org/W1524025855","https://openalex.org/W1561767449","https://openalex.org/W1592652234","https://openalex.org/W1628512331","https://openalex.org/W1963879139","https://openalex.org/W1964750756","https://openalex.org/W1969336855","https://openalex.org/W1978720506","https://openalex.org/W1978823272","https://openalex.org/W1981593440","https://openalex.org/W1983970621","https://openalex.org/W1988927816","https://openalex.org/W1994300590","https://openalex.org/W1994301929","https://openalex.org/W1995203184","https://openalex.org/W1997850825","https://openalex.org/W1997853510","https://openalex.org/W2003435097","https://openalex.org/W2009403023","https://openalex.org/W2014179038","https://openalex.org/W2015132841","https://openalex.org/W2019006831","https://openalex.org/W2022936129","https://openalex.org/W2028003321","https://openalex.org/W2032736838","https://openalex.org/W2033205044","https://openalex.org/W2039778682","https://openalex.org/W2054938702","https://openalex.org/W2060336856","https://openalex.org/W2060870400","https://openalex.org/W2063380020","https://openalex.org/W2064633787","https://openalex.org/W2066185685","https://openalex.org/W2074324848","https://openalex.org/W2075956161","https://openalex.org/W2081022101","https://openalex.org/W2082959814","https://openalex.org/W2090191134","https://openalex.org/W2093385884","https://openalex.org/W2101475372","https://openalex.org/W2102143993","https://openalex.org/W2102619694","https://openalex.org/W2102901123","https://openalex.org/W2103395279","https://openalex.org/W2108014213","https://openalex.org/W2108625845","https://openalex.org/W2114248175","https://openalex.org/W2114982790","https://openalex.org/W2123243207","https://openalex.org/W2133233872","https://openalex.org/W2134051389","https://openalex.org/W2137001129","https://openalex.org/W2139633538","https://openalex.org/W2140045506","https://openalex.org/W2147126535","https://openalex.org/W2155820845","https://openalex.org/W2163721363","https://openalex.org/W2167060626","https://openalex.org/W2183407416"],"related_works":["https://openalex.org/W7039837146","https://openalex.org/W2298773518","https://openalex.org/W2025179624","https://openalex.org/W2900991460","https://openalex.org/W2099847814","https://openalex.org/W1667902255","https://openalex.org/W4254851688","https://openalex.org/W1988927816","https://openalex.org/W2782877394","https://openalex.org/W4318167744"],"abstract_inverted_index":{"We":[0],"analyzed":[1],"modification":[2],"of":[3,28,53,55,61,70,73,106,110,138,171],"chromatin":[4,33,48,143,173],"by":[5,36],"ubiquitination":[6,84,139,170],"in":[7,89,185],"human":[8],"cells":[9,20,156],"and":[10,26,59,101,115,126,148,159,187],"whether":[11],"this":[12,62,191],"mark":[13,63],"changes":[14],"through":[15],"the":[16,29,47,50,74,86,104,141,155,161,169],"cell":[17,163],"cycle.":[18,164],"HeLa":[19],"were":[21,34,77],"synchronized":[22],"at":[23,85,93,140],"different":[24],"stages":[25],"regions":[27,52,88,117],"genome":[30],"with":[31,40,121],"ubiquitinated":[32,79],"identified":[35],"affinity":[37],"purification":[38],"coupled":[39],"next-generation":[41],"sequencing.":[42],"During":[43],"interphase,":[44,119],"ubiquitin":[45],"marked":[46],"on":[49,103],"transcribed":[51,116],"\u223c70%":[54],"highly":[56,78],"active":[57,75,122,180],"genes":[58,76,181],"deposition":[60],"was":[64,97,146,149],"sensitive":[65],"to":[66],"transcriptional":[67,194],"inhibition.":[68],"Promoters":[69],"nearly":[71],"half":[72],"specifically":[80],"during":[81,95,113,118,144,174,182],"mitosis.":[82],"The":[83,135],"coding":[87],"interphase":[90],"but":[91,128],"not":[92,129],"promoters":[94,112],"mitosis":[96,114,145,158,175],"enriched":[98],"for":[99],"ubH2B":[100],"dependent":[102],"presence":[105],"RNF20.":[107],"Ubiquitin":[108],"labeling":[109],"both":[111],"correlated":[120],"histone":[123,132],"marks":[124],"H3K4me3":[125],"H3K36me3":[127],"a":[130,177],"repressive":[131],"modification,":[133],"H3K27me3.":[134],"high":[136],"level":[137],"promoter":[142,172],"transient":[147],"removed":[150],"within":[151],"2":[152],"h":[153],"after":[154],"exited":[157],"entered":[160],"next":[162],"These":[165],"results":[166],"reveal":[167],"that":[168,190],"is":[176],"bookmark":[178],"identifying":[179],"chromosomal":[183],"condensation":[184],"mitosis,":[186],"we":[188],"suggest":[189],"process":[192],"facilitates":[193],"reactivation":[195],"post-mitosis.":[196]},"counts_by_year":[{"year":2022,"cited_by_count":1},{"year":2020,"cited_by_count":2},{"year":2019,"cited_by_count":3},{"year":2015,"cited_by_count":1},{"year":2014,"cited_by_count":1},{"year":2013,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}
