{"id":"https://openalex.org/W1967282137","doi":"https://doi.org/10.1152/ajpheart.00479.2014","title":"Regulation of retinal oxygen metabolism in humans during graded hypoxia","display_name":"Regulation of retinal oxygen metabolism in humans during graded hypoxia","publication_year":2014,"publication_date":"2014-09-13","ids":{"openalex":"https://openalex.org/W1967282137","doi":"https://doi.org/10.1152/ajpheart.00479.2014","mag":"1967282137","pmid":"https://pubmed.ncbi.nlm.nih.gov/25217648"},"language":"en","primary_location":{"id":"doi:10.1152/ajpheart.00479.2014","doi":"https://doi.org/10.1152/ajpheart.00479.2014","is_oa":false,"landing_page_url":"https://doi.org/10.1152/ajpheart.00479.2014","pdf_url":null,"source":{"id":"https://openalex.org/S87338489","display_name":"American Journal of Physiology-Heart and Circulatory Physiology","issn_l":"0363-6135","issn":["0363-6135","1522-1539"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-a","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320261","host_organization_name":"American Physical Society","host_organization_lineage":["https://openalex.org/P4310320261"],"host_organization_lineage_names":["American Physical Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"American Journal of Physiology-Heart and Circulatory Physiology","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5090454655","display_name":"Stefan Palkovits","orcid":"https://orcid.org/0000-0002-0100-9862","observed_orcids":["https://orcid.org/0000-0002-0100-9862"]},"institutions":[{"id":"https://openalex.org/I76134821","display_name":"Medical University of Vienna","ror":"https://ror.org/05n3x4p02","country_code":"AT","type":"education","lineage":["https://openalex.org/I76134821"]}],"countries":["AT"],"is_corresponding":false,"raw_author_name":"Stefan Palkovits","raw_affiliation_strings":["Department of Clinical Pharmacology, Medical University of Vienna, Vienna, Austria;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Clinical Pharmacology, Medical University of Vienna, Vienna, Austria;","institution_ids":["https://openalex.org/I76134821"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5022816056","display_name":"Reinhard Told","orcid":"https://orcid.org/0000-0003-2046-7081","observed_orcids":["https://orcid.org/0000-0003-2046-7081"]},"institutions":[{"id":"https://openalex.org/I76134821","display_name":"Medical University of Vienna","ror":"https://ror.org/05n3x4p02","country_code":"AT","type":"education","lineage":["https://openalex.org/I76134821"]}],"countries":["AT"],"is_corresponding":false,"raw_author_name":"Reinhard Told","raw_affiliation_strings":["Center for Medical Physics and Biomedical Engineering, Medical University of Vienna, Vienna, Austria; and","Department of Clinical Pharmacology, Medical University of Vienna, Vienna, Austria;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Medical Physics and Biomedical Engineering, Medical University of Vienna, Vienna, Austria; and","institution_ids":["https://openalex.org/I76134821"]},{"raw_affiliation_string":"Department of Clinical Pharmacology, Medical University of Vienna, Vienna, Austria;","institution_ids":["https://openalex.org/I76134821"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5012595826","display_name":"Doreen Schmidl","orcid":"https://orcid.org/0000-0001-5664-7768","observed_orcids":["https://orcid.org/0000-0001-5664-7768"]},"institutions":[{"id":"https://openalex.org/I76134821","display_name":"Medical University of Vienna","ror":"https://ror.org/05n3x4p02","country_code":"AT","type":"education","lineage":["https://openalex.org/I76134821"]}],"countries":["AT"],"is_corresponding":false,"raw_author_name":"Doreen Schmidl","raw_affiliation_strings":["Center for Medical Physics and Biomedical Engineering, Medical University of Vienna, Vienna, Austria; and","Department of Clinical Pharmacology, Medical University of Vienna, Vienna, Austria;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Medical Physics and Biomedical Engineering, Medical University of Vienna, Vienna, Austria; and","institution_ids":["https://openalex.org/I76134821"]},{"raw_affiliation_string":"Department of Clinical Pharmacology, Medical University of Vienna, Vienna, Austria;","institution_ids":["https://openalex.org/I76134821"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5066880090","display_name":"Agnes Boltz","orcid":"https://orcid.org/0000-0001-6519-3964","observed_orcids":["https://orcid.org/0000-0001-6519-3964"]},"institutions":[{"id":"https://openalex.org/I76134821","display_name":"Medical University of Vienna","ror":"https://ror.org/05n3x4p02","country_code":"AT","type":"education","lineage":["https://openalex.org/I76134821"]}],"countries":["AT"],"is_corresponding":false,"raw_author_name":"Agnes Boltz","raw_affiliation_strings":["Center for Medical Physics and Biomedical Engineering, Medical University of Vienna, Vienna, Austria; and","Department of Clinical Pharmacology, Medical University of Vienna, Vienna, Austria;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Medical Physics and Biomedical Engineering, Medical University of Vienna, Vienna, Austria; and","institution_ids":["https://openalex.org/I76134821"]},{"raw_affiliation_string":"Department of Clinical Pharmacology, Medical University of Vienna, Vienna, Austria;","institution_ids":["https://openalex.org/I76134821"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108423410","display_name":"Katarzyna J Napora","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I76134821","display_name":"Medical University of Vienna","ror":"https://ror.org/05n3x4p02","country_code":"AT","type":"education","lineage":["https://openalex.org/I76134821"]}],"countries":["AT"],"is_corresponding":false,"raw_author_name":"Katarzyna J. Napora","raw_affiliation_strings":["Department of Clinical Pharmacology, Medical University of Vienna, Vienna, Austria;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Clinical Pharmacology, Medical University of Vienna, Vienna, Austria;","institution_ids":["https://openalex.org/I76134821"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5068801182","display_name":"Michael Lasta","orcid":"https://orcid.org/0000-0002-0729-6110","observed_orcids":["https://orcid.org/0000-0002-0729-6110"]},"institutions":[{"id":"https://openalex.org/I76134821","display_name":"Medical University of Vienna","ror":"https://ror.org/05n3x4p02","country_code":"AT","type":"education","lineage":["https://openalex.org/I76134821"]}],"countries":["AT"],"is_corresponding":false,"raw_author_name":"Michael Lasta","raw_affiliation_strings":["Department of Clinical Pharmacology, Medical University of Vienna, Vienna, Austria;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Clinical Pharmacology, Medical University of Vienna, Vienna, Austria;","institution_ids":["https://openalex.org/I76134821"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113468122","display_name":"Semira Kaya","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I76134821","display_name":"Medical University of Vienna","ror":"https://ror.org/05n3x4p02","country_code":"AT","type":"education","lineage":["https://openalex.org/I76134821"]}],"countries":["AT"],"is_corresponding":false,"raw_author_name":"Semira Kaya","raw_affiliation_strings":["Department of Clinical Pharmacology, Medical University of Vienna, Vienna, Austria;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Clinical Pharmacology, Medical University of Vienna, Vienna, Austria;","institution_ids":["https://openalex.org/I76134821"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5019225873","display_name":"Ren\u00e9 Marcel Werkmeister","orcid":"https://orcid.org/0000-0002-5147-5714","observed_orcids":["https://orcid.org/0000-0002-5147-5714"]},"institutions":[{"id":"https://openalex.org/I76134821","display_name":"Medical University of Vienna","ror":"https://ror.org/05n3x4p02","country_code":"AT","type":"education","lineage":["https://openalex.org/I76134821"]}],"countries":["AT"],"is_corresponding":false,"raw_author_name":"Ren\u00e9 M. Werkmeister","raw_affiliation_strings":["Center for Medical Physics and Biomedical Engineering, Medical University of Vienna, Vienna, Austria; and"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Medical Physics and Biomedical Engineering, Medical University of Vienna, Vienna, Austria; and","institution_ids":["https://openalex.org/I76134821"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5086679794","display_name":"Alina Popa\u2010Cherecheanu","orcid":"https://orcid.org/0000-0003-4189-6571","observed_orcids":["https://orcid.org/0000-0003-4189-6571"]},"institutions":[{"id":"https://openalex.org/I2799655038","display_name":"Clinical Emergency Hospital Bucharest","ror":"https://ror.org/03grprm46","country_code":"RO","type":"healthcare","lineage":["https://openalex.org/I2799655038"]},{"id":"https://openalex.org/I4388891865","display_name":"Bucharest Emergency University Hospital","ror":"https://ror.org/051v1dy68","country_code":"RO","type":"healthcare","lineage":["https://openalex.org/I4388891865"]}],"countries":["RO"],"is_corresponding":false,"raw_author_name":"Alina Popa-Cherecheanu","raw_affiliation_strings":["Department of Ophthalmology, Emergency University Hospital, Bucharest, Romania"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Ophthalmology, Emergency University Hospital, Bucharest, Romania","institution_ids":["https://openalex.org/I2799655038","https://openalex.org/I4388891865"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5060581148","display_name":"Gerhard Garh\u00f6fer","orcid":"https://orcid.org/0000-0001-5547-5669","observed_orcids":["https://orcid.org/0000-0001-5547-5669"]},"institutions":[{"id":"https://openalex.org/I76134821","display_name":"Medical University of Vienna","ror":"https://ror.org/05n3x4p02","country_code":"AT","type":"education","lineage":["https://openalex.org/I76134821"]}],"countries":["AT"],"is_corresponding":false,"raw_author_name":"Gerhard Garh\u00f6fer","raw_affiliation_strings":["Department of Clinical Pharmacology, Medical University of Vienna, Vienna, Austria;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Clinical Pharmacology, Medical University of Vienna, Vienna, Austria;","institution_ids":["https://openalex.org/I76134821"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5015017045","display_name":"Leopold F. Schmetterer","orcid":"https://orcid.org/0000-0002-7189-1707","observed_orcids":["https://orcid.org/0000-0002-7189-1707"]},"institutions":[{"id":"https://openalex.org/I76134821","display_name":"Medical University of Vienna","ror":"https://ror.org/05n3x4p02","country_code":"AT","type":"education","lineage":["https://openalex.org/I76134821"]}],"countries":["AT"],"is_corresponding":true,"raw_author_name":"Leopold Schmetterer","raw_affiliation_strings":["Center for Medical Physics and Biomedical Engineering, Medical University of Vienna, Vienna, Austria; and","Department of Clinical Pharmacology, Medical University of Vienna, Vienna, Austria;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Medical Physics and Biomedical Engineering, Medical University of Vienna, Vienna, Austria; and","institution_ids":["https://openalex.org/I76134821"]},{"raw_affiliation_string":"Department of Clinical Pharmacology, Medical University of Vienna, Vienna, Austria;","institution_ids":["https://openalex.org/I76134821"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5015017045"],"corresponding_institution_ids":["https://openalex.org/I76134821"],"apc_list":null,"apc_paid":null,"fwci":3.6879,"has_fulltext":false,"cited_by_count":53,"citation_normalized_percentile":{"value":0.92302138,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":93,"max":99},"biblio":{"volume":"307","issue":"10","first_page":"H1412","last_page":"H1418"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11438","display_name":"Retinal Imaging and Analysis","score":0.4812000095844269,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11438","display_name":"Retinal Imaging and Analysis","score":0.4812000095844269,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10170","display_name":"Retinal Diseases and Treatments","score":0.21060000360012054,"subfield":{"id":"https://openalex.org/subfields/2731","display_name":"Ophthalmology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10250","display_name":"Glaucoma and retinal disorders","score":0.04650000110268593,"subfield":{"id":"https://openalex.org/subfields/2731","display_name":"Ophthalmology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/retinal-oxygen-metabolism","display_name":"retinal oxygen metabolism","score":0.925000011920929},{"id":"https://openalex.org/keywords/inner-retina","display_name":"inner retina","score":0.6959999799728394},{"id":"https://openalex.org/keywords/retinal-blood-flow","display_name":"retinal blood flow","score":0.9580000042915344},{"id":"https://openalex.org/keywords/retinal-oxygen-saturation","display_name":"retinal oxygen saturation","score":0.5929999947547913},{"id":"https://openalex.org/keywords/arteriovenous-oxygen-difference","display_name":"arteriovenous oxygen difference","score":0.9760000109672546},{"id":"https://openalex.org/keywords/fundus-reflectometry","display_name":"fundus reflectometry","score":0.6940000057220459},{"id":"https://openalex.org/keywords/laser-doppler-velocimetry","display_name":"laser Doppler anemometry","score":0.9340000152587891},{"id":"https://openalex.org/keywords/retinal-vessel-analyzer","display_name":"Retinal Vessel Analyzer","score":0.8600000143051147},{"id":"https://openalex.org/keywords/hyperbaric-oxygen-therapy","display_name":"hyperbaric oxygen therapy","score":0.5099999904632568},{"id":"https://openalex.org/keywords/normobaric-hypoxia","display_name":"normobaric hypoxia","score":0.652999997138977},{"id":"https://openalex.org/keywords/carbon-dioxide","display_name":"carbon dioxide","score":0.32499998807907104}],"concepts":[{"id":"https://openalex.org/C2780827179","wikidata":"https://www.wikidata.org/wiki/Q422001","display_name":"Retinal","level":2,"score":0.7480660676956177},{"id":"https://openalex.org/C2777093970","wikidata":"https://www.wikidata.org/wiki/Q169342","display_name":"Retina","level":2,"score":0.668830156326294},{"id":"https://openalex.org/C43044207","wikidata":"https://www.wikidata.org/wiki/Q618363","display_name":"Venous blood","level":2,"score":0.5038284659385681},{"id":"https://openalex.org/C2910707947","wikidata":"https://www.wikidata.org/wiki/Q489722","display_name":"Retinal Artery","level":3,"score":0.5000612735748291},{"id":"https://openalex.org/C158846371","wikidata":"https://www.wikidata.org/wiki/Q1642137","display_name":"Blood flow","level":2,"score":0.49987125396728516},{"id":"https://openalex.org/C540031477","wikidata":"https://www.wikidata.org/wiki/Q629","display_name":"Oxygen","level":2,"score":0.47595831751823425},{"id":"https://openalex.org/C39300077","wikidata":"https://www.wikidata.org/wiki/Q9530","display_name":"Breathing","level":2,"score":0.4758840799331665},{"id":"https://openalex.org/C7836513","wikidata":"https://www.wikidata.org/wiki/Q1641506","display_name":"Hypoxia (environmental)","level":3,"score":0.4322265088558197},{"id":"https://openalex.org/C52305850","wikidata":"https://www.wikidata.org/wiki/Q1420475","display_name":"Laser Doppler velocimetry","level":3,"score":0.4118545353412628},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.37035614252090454},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.3576713800430298},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.35644951462745667},{"id":"https://openalex.org/C118487528","wikidata":"https://www.wikidata.org/wiki/Q161437","display_name":"Ophthalmology","level":1,"score":0.32332921028137207},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.2751883268356323},{"id":"https://openalex.org/C42219234","wikidata":"https://www.wikidata.org/wiki/Q131130","display_name":"Anesthesia","level":1,"score":0.2715749442577362},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.0},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000293","descriptor_name":"Adolescent","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000860","descriptor_name":"Hypoxia","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D000860","descriptor_name":"Hypoxia","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D001783","descriptor_name":"Blood Flow Velocity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002245","descriptor_name":"Carbon Dioxide","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010100","descriptor_name":"Oxygen","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D010101","descriptor_name":"Oxygen Consumption","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D010313","descriptor_name":"Partial Pressure","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012039","descriptor_name":"Regional Blood Flow","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012119","descriptor_name":"Respiration","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012160","descriptor_name":"Retina","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D012161","descriptor_name":"Retinal Artery","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":true},{"descriptor_ui":"D012169","descriptor_name":"Retinal Vein","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":true},{"descriptor_ui":"D013997","descriptor_name":"Time Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017078","descriptor_name":"Laser-Doppler Flowmetry","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018592","descriptor_name":"Cross-Over Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D055815","descriptor_name":"Young Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D064368","descriptor_name":"Healthy Volunteers","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1152/ajpheart.00479.2014","doi":"https://doi.org/10.1152/ajpheart.00479.2014","is_oa":false,"landing_page_url":"https://doi.org/10.1152/ajpheart.00479.2014","pdf_url":null,"source":{"id":"https://openalex.org/S87338489","display_name":"American Journal of Physiology-Heart and Circulatory Physiology","issn_l":"0363-6135","issn":["0363-6135","1522-1539"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-a","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320261","host_organization_name":"American Physical Society","host_organization_lineage":["https://openalex.org/P4310320261"],"host_organization_lineage_names":["American Physical Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"American Journal of Physiology-Heart and Circulatory Physiology","raw_type":"journal-article"},{"id":"pmid:25217648","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/25217648","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"American journal of physiology. Heart and circulatory physiology","raw_type":"Journal Article"},{"id":"pmh:oai:CiteSeerX.psu:10.1.1.994.4743","doi":null,"is_oa":false,"landing_page_url":"http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.994.4743","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"http://ajpheart.physiology.org/content/ajpheart/307/10/H1412.full.pdf","raw_type":"text"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.9074000120162964,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":64,"referenced_works":["https://openalex.org/W60773599","https://openalex.org/W561411057","https://openalex.org/W1516136009","https://openalex.org/W1561418783","https://openalex.org/W1562374674","https://openalex.org/W1576343099","https://openalex.org/W1595136073","https://openalex.org/W1965338634","https://openalex.org/W1969233109","https://openalex.org/W1972462453","https://openalex.org/W1981210992","https://openalex.org/W1981918735","https://openalex.org/W1982020416","https://openalex.org/W1982660808","https://openalex.org/W1983781412","https://openalex.org/W1986933169","https://openalex.org/W1993339149","https://openalex.org/W2001933578","https://openalex.org/W2003279014","https://openalex.org/W2003531547","https://openalex.org/W2008591928","https://openalex.org/W2011540186","https://openalex.org/W2012027777","https://openalex.org/W2022344985","https://openalex.org/W2026787873","https://openalex.org/W2026880386","https://openalex.org/W2027799106","https://openalex.org/W2032801058","https://openalex.org/W2032891373","https://openalex.org/W2033492815","https://openalex.org/W2038421583","https://openalex.org/W2041245457","https://openalex.org/W2047062615","https://openalex.org/W2048616942","https://openalex.org/W2053135239","https://openalex.org/W2063112863","https://openalex.org/W2068092592","https://openalex.org/W2069410893","https://openalex.org/W2073436318","https://openalex.org/W2078683991","https://openalex.org/W2081280259","https://openalex.org/W2081985889","https://openalex.org/W2083922350","https://openalex.org/W2084857051","https://openalex.org/W2086831074","https://openalex.org/W2087678619","https://openalex.org/W2097524398","https://openalex.org/W2105505313","https://openalex.org/W2108304661","https://openalex.org/W2112479900","https://openalex.org/W2129016682","https://openalex.org/W2130465304","https://openalex.org/W2136600016","https://openalex.org/W2141079951","https://openalex.org/W2141673118","https://openalex.org/W2144795002","https://openalex.org/W2147762989","https://openalex.org/W2148843570","https://openalex.org/W2149998410","https://openalex.org/W2151103139","https://openalex.org/W2165790411","https://openalex.org/W2174556627","https://openalex.org/W2280197148","https://openalex.org/W4243453612"],"related_works":["https://openalex.org/W2316197291","https://openalex.org/W4406595858","https://openalex.org/W2012333097","https://openalex.org/W2144103797","https://openalex.org/W2090738706","https://openalex.org/W605224835","https://openalex.org/W2069410893","https://openalex.org/W7095552254","https://openalex.org/W2032801058","https://openalex.org/W2520745033"],"abstract_inverted_index":{"Animal":[0],"experiments":[1,241],"indicate":[2,260],"that":[3,29,261],"the":[4,16,24,268],"inner":[5,35,269],"retina":[6,18,270],"keeps":[7],"its":[8],"oxygen":[9,37,211,233,265],"extraction":[10,234,266],"constant":[11,272],"despite":[12],"systemic":[13,30,274],"hypoxia.":[14,275],"For":[15],"human":[17],"no":[19],"such":[20],"data":[21],"exist.":[22],"In":[23],"present":[25],"study":[26],"we":[27,43],"hypothesized":[28],"hypoxia":[31],"does":[32],"not":[33,237],"alter":[34],"retinal":[36,84,90,101,111,124],"extraction.":[38],"To":[39],"test":[40],"this":[41],"hypothesis":[42],"included":[44],"30":[45],"healthy":[46,263],"male":[47],"and":[48,54,63,87,110,128,152,161,191],"female":[49],"subjects":[50,58],"aged":[51],"between":[52],"18":[53],"35":[55],"years.":[56],"All":[57],"were":[59,93,120,133],"studied":[60],"at":[61],"baseline":[62],"during":[64,159,172,214,239,273],"breathing":[65,74,176,194,216],"12%":[66,160,174],"O\u2082":[67,76,163,175,193],"in":[68,77,82,262],"88%":[69],"N\u2082":[70],"as":[71,73,167,169],"well":[72,168],"15%":[75,162,192,223,250],"85%":[78],"N\u2082.":[79],"Oxygen":[80,127],"saturation":[81],"a":[83,115],"artery":[85],"(SO\u2082art)":[86],"an":[88],"adjacent":[89],"vein":[91],"(SO\u2082vein)":[92],"measured":[94,134],"using":[95,105,114],"spectroscopic":[96],"fundus":[97],"reflectometry.":[98],"Measurements":[99],"of":[100,267],"venous":[102,112],"blood":[103,125,141],"velocity":[104],"bidirectional":[106],"laser":[107],"Doppler":[108],"velocimetry":[109],"diameters":[113],"Retinal":[116,140],"Vessel":[117],"Analyzer":[118],"(RVA)":[119],"combined":[121],"to":[122],"calculate":[123],"flow.":[126],"carbon":[129],"dioxide":[130],"partial":[131],"pressure":[132],"from":[135],"earlobe":[136],"arterialized":[137],"capillary":[138],"blood.":[139],"flow":[142],"was":[143],"increased":[144],"by":[145],"43.0":[146],"\u00b1":[147,154,179,186,197,204,221,226,245,253],"23.2%":[148],"(P":[149,156],"<":[150,157,182,200,229],"0.001)":[151,158],"30.0":[153],"20.9%":[155],"breathing,":[164],"respectively.":[165],"SO\u2082art":[166],"SO\u2082vein":[170],"decreased":[171,213],"both":[173,215],"(SO\u2082art:":[177,195],"-11.2":[178],"4.3%,":[180],"P":[181,188,199,206,228,247,255],"0.001;":[183,201],"SO\u2082vein:":[184,202],"-3.9":[185],"8.5%,":[187],"=":[189,207,248,256],"0.012)":[190],"-7.9":[196],"3.6%,":[198],"-4.0":[203],"7.0%,":[205],"0.010).":[208],"The":[209],"arteriovenous":[210],"difference":[212],"periods":[217],"(12%":[218,242],"O2:":[219],"-28.9":[220],"18.7%;":[222],"O\u2082:":[224,243,251],"-19.1":[225],"16.7%,":[227],"0.001":[230],"each).":[231],"Calculated":[232],"did,":[235],"however,":[236],"change":[238],"our":[240],"-2.8":[244],"18.9%,":[246],"0.65;":[249],"2.4":[252],"15.8%,":[254],"0.26).":[257],"Our":[258],"results":[259],"humans,":[264],"remains":[271]},"counts_by_year":[{"year":2026,"cited_by_count":3},{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":5},{"year":2023,"cited_by_count":4},{"year":2022,"cited_by_count":6},{"year":2021,"cited_by_count":3},{"year":2020,"cited_by_count":3},{"year":2019,"cited_by_count":5},{"year":2018,"cited_by_count":6},{"year":2017,"cited_by_count":5},{"year":2016,"cited_by_count":4},{"year":2015,"cited_by_count":7}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}
