{"id":"https://openalex.org/W1966991127","doi":"https://doi.org/10.1016/s0166-2236(00)01576-9","title":"Actin and the agile spine: how and why do dendritic spines dance?","display_name":"Actin and the agile spine: how and why do dendritic spines dance?","publication_year":2000,"publication_date":"2000-04-01","ids":{"openalex":"https://openalex.org/W1966991127","doi":"https://doi.org/10.1016/s0166-2236(00)01576-9","mag":"1966991127","pmid":"https://pubmed.ncbi.nlm.nih.gov/10717670"},"language":"en","primary_location":{"id":"doi:10.1016/s0166-2236(00)01576-9","doi":"https://doi.org/10.1016/s0166-2236(00)01576-9","is_oa":false,"landing_page_url":"https://doi.org/10.1016/s0166-2236(00)01576-9","pdf_url":null,"source":{"id":"https://openalex.org/S114966740","display_name":"Trends in Neurosciences","issn_l":"0166-2236","issn":["0166-2236","1878-108X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-3","ki-jl-1","medline","norway-1","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Trends in Neurosciences","raw_type":"journal-article"},"volume":null,"type":"review","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5089753548","display_name":"Shelley Halpain","orcid":"https://orcid.org/0000-0002-7480-5157","observed_orcids":["https://orcid.org/0000-0002-7480-5157"]},"institutions":[{"id":"https://openalex.org/I123431417","display_name":"Scripps Research Institute","ror":"https://ror.org/02dxx6824","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I123431417"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Shelley Halpain","raw_affiliation_strings":["Dept of Cell Biology, The Scripps Research Institute, La Jolla, CA 92037, USA","Department of Cell Biology,  The Scripps Research Institute, La Jolla, CA 92037, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Dept of Cell Biology, The Scripps Research Institute, La Jolla, CA 92037, USA","institution_ids":["https://openalex.org/I123431417"]},{"raw_affiliation_string":"Department of Cell Biology,  The Scripps Research Institute, La Jolla, CA 92037, USA","institution_ids":["https://openalex.org/I123431417"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5089753548"],"corresponding_institution_ids":["https://openalex.org/I123431417"],"apc_list":{"value":7030,"currency":"USD","value_usd":7030},"apc_paid":null,"fwci":1.4797,"has_fulltext":false,"cited_by_count":176,"citation_normalized_percentile":{"value":0.80986938,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":99},"biblio":{"volume":"23","issue":"4","first_page":"141","last_page":"146"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10077","display_name":"Neuroscience and Neuropharmacology Research","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10077","display_name":"Neuroscience and Neuropharmacology Research","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11772","display_name":"Genetics and Neurodevelopmental Disorders","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10379","display_name":"Cellular Mechanics and Interactions","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/dendritic-spines","display_name":"dendritic spines","score":0.9959999918937683},{"id":"https://openalex.org/keywords/actin-filaments","display_name":"F-actin","score":0.8569999933242798},{"id":"https://openalex.org/keywords/spine-motility","display_name":"spine motility","score":0.9390000104904175},{"id":"https://openalex.org/keywords/spine-morphology","display_name":"dendritic spine morphology","score":0.5960000157356262},{"id":"https://openalex.org/keywords/protein-scaffolding","display_name":"protein scaffolding","score":0.8199999928474426},{"id":"https://openalex.org/keywords/retrograde-signaling","display_name":"retrograde signaling","score":0.9950000047683716},{"id":"https://openalex.org/keywords/synapse-stabilization","display_name":"synapse stabilization","score":0.9739999771118164}],"concepts":[{"id":"https://openalex.org/C174884520","wikidata":"https://www.wikidata.org/wiki/Q902079","display_name":"Dendritic spine","level":3,"score":0.8732804656028748},{"id":"https://openalex.org/C205383261","wikidata":"https://www.wikidata.org/wiki/Q7392570","display_name":"SPINE (molecular biology)","level":2,"score":0.7714012861251831},{"id":"https://openalex.org/C53250682","wikidata":"https://www.wikidata.org/wiki/Q5256674","display_name":"Dendritic filopodia","level":4,"score":0.6843262314796448},{"id":"https://openalex.org/C58207958","wikidata":"https://www.wikidata.org/wiki/Q33596","display_name":"Motility","level":2,"score":0.6207185983657837},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.608718991279602},{"id":"https://openalex.org/C151000934","wikidata":"https://www.wikidata.org/wiki/Q4676834","display_name":"Actin remodeling of neurons","level":5,"score":0.5569936037063599},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.5205851197242737},{"id":"https://openalex.org/C125705527","wikidata":"https://www.wikidata.org/wiki/Q185269","display_name":"Actin","level":2,"score":0.494219571352005},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.4722568094730377},{"id":"https://openalex.org/C127445978","wikidata":"https://www.wikidata.org/wiki/Q187181","display_name":"Synapse","level":2,"score":0.4443088173866272},{"id":"https://openalex.org/C2993400109","wikidata":"https://www.wikidata.org/wiki/Q329638","display_name":"Actin cytoskeleton","level":4,"score":0.3307217061519623},{"id":"https://openalex.org/C142669718","wikidata":"https://www.wikidata.org/wiki/Q154626","display_name":"Cytoskeleton","level":3,"score":0.24744734168052673},{"id":"https://openalex.org/C1491633281","wikidata":"https://www.wikidata.org/wiki/Q7868","display_name":"Cell","level":2,"score":0.1307883858680725},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0},{"id":"https://openalex.org/C148762608","wikidata":"https://www.wikidata.org/wiki/Q3748185","display_name":"Hippocampal formation","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000199","descriptor_name":"Actins","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003599","descriptor_name":"Cytoskeleton","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D003599","descriptor_name":"Cytoskeleton","qualifier_ui":"Q000648","qualifier_name":"ultrastructure","is_major_topic":false},{"descriptor_ui":"D003712","descriptor_name":"Dendrites","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D003712","descriptor_name":"Dendrites","qualifier_ui":"Q000648","qualifier_name":"ultrastructure","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1016/s0166-2236(00)01576-9","doi":"https://doi.org/10.1016/s0166-2236(00)01576-9","is_oa":false,"landing_page_url":"https://doi.org/10.1016/s0166-2236(00)01576-9","pdf_url":null,"source":{"id":"https://openalex.org/S114966740","display_name":"Trends in Neurosciences","issn_l":"0166-2236","issn":["0166-2236","1878-108X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-3","ki-jl-1","medline","norway-1","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Trends in Neurosciences","raw_type":"journal-article"},{"id":"pmid:10717670","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/10717670","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Trends in neurosciences","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":69,"referenced_works":["https://openalex.org/W1527585999","https://openalex.org/W1569092853","https://openalex.org/W1572640432","https://openalex.org/W1600951028","https://openalex.org/W1677457722","https://openalex.org/W1796802340","https://openalex.org/W1859826371","https://openalex.org/W1901241211","https://openalex.org/W1917414302","https://openalex.org/W1961436367","https://openalex.org/W1966706797","https://openalex.org/W1966759575","https://openalex.org/W1970111700","https://openalex.org/W1972172786","https://openalex.org/W1972884505","https://openalex.org/W1975782461","https://openalex.org/W1977805593","https://openalex.org/W1986435945","https://openalex.org/W1991004364","https://openalex.org/W2001606679","https://openalex.org/W2002190857","https://openalex.org/W2011734517","https://openalex.org/W2012418765","https://openalex.org/W2015328445","https://openalex.org/W2019121351","https://openalex.org/W2025336218","https://openalex.org/W2029815010","https://openalex.org/W2037921808","https://openalex.org/W2038915296","https://openalex.org/W2038940222","https://openalex.org/W2040493288","https://openalex.org/W2041624665","https://openalex.org/W2042202484","https://openalex.org/W2045257232","https://openalex.org/W2051541374","https://openalex.org/W2054022110","https://openalex.org/W2066002146","https://openalex.org/W2072059048","https://openalex.org/W2072240979","https://openalex.org/W2074322379","https://openalex.org/W2076848103","https://openalex.org/W2077476134","https://openalex.org/W2083840419","https://openalex.org/W2088984430","https://openalex.org/W2096791952","https://openalex.org/W2096918711","https://openalex.org/W2101473364","https://openalex.org/W2103762808","https://openalex.org/W2106267269","https://openalex.org/W2110065479","https://openalex.org/W2111916392","https://openalex.org/W2117664079","https://openalex.org/W2123729988","https://openalex.org/W2126250161","https://openalex.org/W2129090701","https://openalex.org/W2130183688","https://openalex.org/W2132349554","https://openalex.org/W2136249808","https://openalex.org/W2144620740","https://openalex.org/W2144796435","https://openalex.org/W2146831587","https://openalex.org/W2152371902","https://openalex.org/W2154505735","https://openalex.org/W2156678388","https://openalex.org/W2163031440","https://openalex.org/W2242792050","https://openalex.org/W2471521183","https://openalex.org/W4249424055","https://openalex.org/W4301037431"],"related_works":["https://openalex.org/W2165167544","https://openalex.org/W2114129553","https://openalex.org/W2079956982","https://openalex.org/W3094395164","https://openalex.org/W2034190641","https://openalex.org/W2101176534","https://openalex.org/W7101092838","https://openalex.org/W7096965677","https://openalex.org/W2054366304","https://openalex.org/W2127861262"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":2},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":4},{"year":2020,"cited_by_count":2},{"year":2019,"cited_by_count":3},{"year":2018,"cited_by_count":3},{"year":2017,"cited_by_count":6},{"year":2016,"cited_by_count":10},{"year":2015,"cited_by_count":2},{"year":2014,"cited_by_count":7},{"year":2013,"cited_by_count":8},{"year":2012,"cited_by_count":11}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2016-06-24T00:00:00"}