{"id":"https://openalex.org/W1966793992","doi":"https://doi.org/10.1016/0378-1119(94)90544-4","title":"A negative cis-acting G-fer element participates in the regulation of expression of the human H-ferritin-encoding gene (FERH)","display_name":"A negative cis-acting G-fer element participates in the regulation of expression of the human H-ferritin-encoding gene (FERH)","publication_year":1994,"publication_date":"1994-03-01","ids":{"openalex":"https://openalex.org/W1966793992","doi":"https://doi.org/10.1016/0378-1119(94)90544-4","mag":"1966793992","pmid":"https://pubmed.ncbi.nlm.nih.gov/8144027"},"language":"en","primary_location":{"id":"doi:10.1016/0378-1119(94)90544-4","doi":"https://doi.org/10.1016/0378-1119(94)90544-4","is_oa":false,"landing_page_url":"https://doi.org/10.1016/0378-1119(94)90544-4","pdf_url":null,"source":{"id":"https://openalex.org/S75702506","display_name":"Gene","issn_l":"0378-1119","issn":["0378-1119","1879-0038"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Gene","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5004832378","display_name":"Renata Barresi","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I83816512","display_name":"University of Genoa","ror":"https://ror.org/0107c5v14","country_code":"IT","type":"education","lineage":["https://openalex.org/I83816512"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Renata Barresi","raw_affiliation_strings":["Institute of Biology and Genetics, University of Genova, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Biology and Genetics, University of Genova, Italy","institution_ids":["https://openalex.org/I83816512"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5037660184","display_name":"Mario Sirito","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I83816512","display_name":"University of Genoa","ror":"https://ror.org/0107c5v14","country_code":"IT","type":"education","lineage":["https://openalex.org/I83816512"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Mario Sirito","raw_affiliation_strings":["Institute of Biology and Genetics (IBIG), University of Genova, 16132 Geneva, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Biology and Genetics (IBIG), University of Genova, 16132 Geneva, Italy","institution_ids":["https://openalex.org/I83816512"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5086824931","display_name":"G\u00e9rard Karsenty","orcid":"https://orcid.org/0000-0002-9253-7627","observed_orcids":["https://orcid.org/0000-0002-9253-7627","https://orcid.org/0000-0002-9047-3332"]},"institutions":[{"id":"https://openalex.org/I1343551460","display_name":"The University of Texas MD Anderson Cancer Center","ror":"https://ror.org/04twxam07","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1343551460"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Gerard Karsenty","raw_affiliation_strings":["Department of Molecular Genetics, The University of Texas,bM.D. Anderson Cancer Center, Houston, TX 77030, U.S.A. Tel. ( 1-713 ) 792-2574"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Molecular Genetics, The University of Texas,bM.D. Anderson Cancer Center, Houston, TX 77030, U.S.A. Tel. ( 1-713 ) 792-2574","institution_ids":["https://openalex.org/I1343551460"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5073453050","display_name":"Roberto Ravazzolo","orcid":"https://orcid.org/0009-0007-6923-738X","observed_orcids":["https://orcid.org/0009-0007-6923-738X"]},"institutions":[{"id":"https://openalex.org/I83816512","display_name":"University of Genoa","ror":"https://ror.org/0107c5v14","country_code":"IT","type":"education","lineage":["https://openalex.org/I83816512"]}],"countries":["IT"],"is_corresponding":true,"raw_author_name":"Roberto Ravazzolo","raw_affiliation_strings":["Institute of Biology and Genetics (IBIG), University of Genova, 16132 Geneva, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Biology and Genetics (IBIG), University of Genova, 16132 Geneva, Italy","institution_ids":["https://openalex.org/I83816512"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5073453050"],"corresponding_institution_ids":["https://openalex.org/I83816512"],"apc_list":{"value":3300,"currency":"USD","value_usd":3300},"apc_paid":null,"fwci":1.3543,"has_fulltext":false,"cited_by_count":17,"citation_normalized_percentile":{"value":0.8009382,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":94},"biblio":{"volume":"140","issue":"2","first_page":"195","last_page":"201"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10452","display_name":"Iron Metabolism and Disorders","score":0.9243000149726868,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10452","display_name":"Iron Metabolism and Disorders","score":0.9243000149726868,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10222","display_name":"Genomics and Chromatin Dynamics","score":0.06949999928474426,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11418","display_name":"Plant Micronutrient Interactions and Effects","score":0.00039999998989515007,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/h-ferritin","display_name":"H-ferritin","score":0.8360000252723694},{"id":"https://openalex.org/keywords/cis-regulatory-elements","display_name":"cis-regulatory elements","score":0.7400000095367432},{"id":"https://openalex.org/keywords/transcriptional-regulation","display_name":"transcriptional regulation","score":0.8840000033378601},{"id":"https://openalex.org/keywords/g-rich-dna-sequences","display_name":"G-rich DNA sequences","score":0.5559999942779541},{"id":"https://openalex.org/keywords/promoter-analysis","display_name":"promoter analysis","score":0.453000009059906},{"id":"https://openalex.org/keywords/iron-storage-protein","display_name":"iron storage protein","score":0.675000011920929},{"id":"https://openalex.org/keywords/dna-binding-proteins","display_name":"DNA-binding proteins","score":0.44200000166893005},{"id":"https://openalex.org/keywords/promoter-mutations","display_name":"promoter mutations","score":0.35499998927116394}],"concepts":[{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.8249043822288513},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.7119870185852051},{"id":"https://openalex.org/C101762097","wikidata":"https://www.wikidata.org/wiki/Q224093","display_name":"Promoter","level":4,"score":0.703606128692627},{"id":"https://openalex.org/C161733203","wikidata":"https://www.wikidata.org/wiki/Q911828","display_name":"Reporter gene","level":4,"score":0.6616094708442688},{"id":"https://openalex.org/C153911025","wikidata":"https://www.wikidata.org/wiki/Q7202","display_name":"Molecular biology","level":1,"score":0.6194901466369629},{"id":"https://openalex.org/C2778319317","wikidata":"https://www.wikidata.org/wiki/Q22327449","display_name":"Ferritin","level":2,"score":0.5829176902770996},{"id":"https://openalex.org/C27153228","wikidata":"https://www.wikidata.org/wiki/Q3787274","display_name":"Transcriptional regulation","level":4,"score":0.5211722254753113},{"id":"https://openalex.org/C552990157","wikidata":"https://www.wikidata.org/wiki/Q7430","display_name":"DNA","level":2,"score":0.510576605796814},{"id":"https://openalex.org/C54009773","wikidata":"https://www.wikidata.org/wiki/Q1429031","display_name":"Transfection","level":3,"score":0.4984283447265625},{"id":"https://openalex.org/C2778061764","wikidata":"https://www.wikidata.org/wiki/Q6987253","display_name":"Negative regulatory element","level":5,"score":0.4845125079154968},{"id":"https://openalex.org/C501734568","wikidata":"https://www.wikidata.org/wiki/Q42918","display_name":"Mutation","level":3,"score":0.46204301714897156},{"id":"https://openalex.org/C21592294","wikidata":"https://www.wikidata.org/wiki/Q3238407","display_name":"Regulatory sequence","level":4,"score":0.43110978603363037},{"id":"https://openalex.org/C165864922","wikidata":"https://www.wikidata.org/wiki/Q411391","display_name":"Regulation of gene expression","level":3,"score":0.4302871525287628},{"id":"https://openalex.org/C150194340","wikidata":"https://www.wikidata.org/wiki/Q26972","display_name":"Gene expression","level":3,"score":0.37924233078956604},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.332084059715271},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.12541505694389343}],"mesh":[{"descriptor_ui":"D001665","descriptor_name":"Binding Sites","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003094","descriptor_name":"Collagen","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D005293","descriptor_name":"Ferritins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D005786","descriptor_name":"Gene Expression Regulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D006367","descriptor_name":"HeLa Cells","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009154","descriptor_name":"Mutation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009928","descriptor_name":"Organ Specificity","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D011401","descriptor_name":"Promoter Regions, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012045","descriptor_name":"Regulatory Sequences, Nucleic Acid","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D014162","descriptor_name":"Transfection","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1016/0378-1119(94)90544-4","doi":"https://doi.org/10.1016/0378-1119(94)90544-4","is_oa":false,"landing_page_url":"https://doi.org/10.1016/0378-1119(94)90544-4","pdf_url":null,"source":{"id":"https://openalex.org/S75702506","display_name":"Gene","issn_l":"0378-1119","issn":["0378-1119","1879-0038"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Gene","raw_type":"journal-article"},{"id":"pmid:8144027","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/8144027","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Gene","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":21,"referenced_works":["https://openalex.org/W1505571690","https://openalex.org/W1511180136","https://openalex.org/W1540748404","https://openalex.org/W1558516755","https://openalex.org/W1568633060","https://openalex.org/W1587498598","https://openalex.org/W1710867374","https://openalex.org/W1954929088","https://openalex.org/W1964405527","https://openalex.org/W1981765089","https://openalex.org/W1993243592","https://openalex.org/W1993277839","https://openalex.org/W1995646607","https://openalex.org/W2016762244","https://openalex.org/W2045152859","https://openalex.org/W2050328515","https://openalex.org/W2071769587","https://openalex.org/W2073762081","https://openalex.org/W2089126365","https://openalex.org/W2122414439","https://openalex.org/W2417785890"],"related_works":["https://openalex.org/W1503059876","https://openalex.org/W2017181048","https://openalex.org/W2153857565","https://openalex.org/W2033969239","https://openalex.org/W1964405527","https://openalex.org/W2019914595","https://openalex.org/W2145822336","https://openalex.org/W2015892667","https://openalex.org/W978424969","https://openalex.org/W2023361302"],"abstract_inverted_index":null,"counts_by_year":[{"year":2013,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}