{"id":"https://openalex.org/W1966652190","doi":"https://doi.org/10.1007/bf00142691","title":"Treatment of cytomegalovirus retinitis with DHPG in a patient with AIDS","display_name":"Treatment of cytomegalovirus retinitis with DHPG in a patient with AIDS","publication_year":1987,"publication_date":"1987-01-01","ids":{"openalex":"https://openalex.org/W1966652190","doi":"https://doi.org/10.1007/bf00142691","mag":"1966652190","pmid":"https://pubmed.ncbi.nlm.nih.gov/2827978"},"language":"en","primary_location":{"id":"doi:10.1007/bf00142691","doi":"https://doi.org/10.1007/bf00142691","is_oa":false,"landing_page_url":"https://doi.org/10.1007/bf00142691","pdf_url":null,"source":{"id":"https://openalex.org/S6331754","display_name":"Documenta Ophthalmologica","issn_l":"0012-4486","issn":["0012-4486","1573-2622"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","medline","norway-1","poland-100","russia-white-list-2"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Documenta Ophthalmologica","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5110177518","display_name":"J. M. M. Hooymans","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1334415907","display_name":"University Medical Center Groningen","ror":"https://ror.org/03cv38k47","country_code":"NL","type":"healthcare","lineage":["https://openalex.org/I1334415907"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"J. M. M. Hooymans","raw_affiliation_strings":["Department of Ophthalmology, University Hospital, Groningen, The Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Ophthalmology, University Hospital, Groningen, The Netherlands","institution_ids":["https://openalex.org/I1334415907"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108584048","display_name":"Herman G. Sprenger","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1334415907","display_name":"University Medical Center Groningen","ror":"https://ror.org/03cv38k47","country_code":"NL","type":"healthcare","lineage":["https://openalex.org/I1334415907"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"H. G. Sprenger","raw_affiliation_strings":["Infections Disease Unit, Department of Medicine, University Hospital, Oostersingel 59, 9713 EZ, Groningen, the Netherlands","Infections Disease Unit, Department of Medicine, University Hospital, Groningen, the Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Infections Disease Unit, Department of Medicine, University Hospital, Oostersingel 59, 9713 EZ, Groningen, the Netherlands","institution_ids":["https://openalex.org/I1334415907"]},{"raw_affiliation_string":"Infections Disease Unit, Department of Medicine, University Hospital, Groningen, the Netherlands","institution_ids":["https://openalex.org/I1334415907"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5111878685","display_name":"Jan Weits","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1334415907","display_name":"University Medical Center Groningen","ror":"https://ror.org/03cv38k47","country_code":"NL","type":"healthcare","lineage":["https://openalex.org/I1334415907"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"J. Weits","raw_affiliation_strings":["Infections Disease Unit, Department of Medicine, University Hospital, Oostersingel 59, 9713 EZ, Groningen, the Netherlands","Infections Disease Unit, Department of Medicine, University Hospital, Groningen, the Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Infections Disease Unit, Department of Medicine, University Hospital, Oostersingel 59, 9713 EZ, Groningen, the Netherlands","institution_ids":["https://openalex.org/I1334415907"]},{"raw_affiliation_string":"Infections Disease Unit, Department of Medicine, University Hospital, Groningen, the Netherlands","institution_ids":["https://openalex.org/I1334415907"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I1334415907"],"apc_list":{"value":4090,"currency":"USD","value_usd":4090},"apc_paid":null,"fwci":0.2926,"has_fulltext":false,"cited_by_count":6,"citation_normalized_percentile":{"value":0.55664858,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":94},"biblio":{"volume":"67","issue":"1-2","first_page":"5","last_page":"12"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10981","display_name":"Cytomegalovirus and herpesvirus research","score":0.8838000297546387,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10981","display_name":"Cytomegalovirus and herpesvirus research","score":0.8838000297546387,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11826","display_name":"Ocular Infections and Treatments","score":0.07429999858140945,"subfield":{"id":"https://openalex.org/subfields/2731","display_name":"Ophthalmology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10625","display_name":"Herpesvirus Infections and Treatments","score":0.019099999219179153,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/cytomegalovirus-retinitis","display_name":"cytomegalovirus retinitis","score":0.9980000257492065},{"id":"https://openalex.org/keywords/dhpg","display_name":"DHPG","score":0.8669999837875366},{"id":"https://openalex.org/keywords/acyclic-nucleoside-analogues","display_name":"acyclic nucleoside analogues","score":0.6190000176429749},{"id":"https://openalex.org/keywords/aids","display_name":"AIDS","score":0.781000018119812},{"id":"https://openalex.org/keywords/optic-neuritis","display_name":"optic neuritis","score":0.8550000190734863},{"id":"https://openalex.org/keywords/serous-retinal-detachment","display_name":"serous retinal detachment","score":0.9480000138282776},{"id":"https://openalex.org/keywords/antiviral-therapy","display_name":"antiviral therapy","score":0.7929999828338623},{"id":"https://openalex.org/keywords/suppressive-therapy","display_name":"suppressive therapy","score":0.6970000267028809},{"id":"https://openalex.org/keywords/neutropenia","display_name":"neutropenia","score":0.7390000224113464},{"id":"https://openalex.org/keywords/visual-acuity","display_name":"visual acuity","score":0.7789999842643738}],"concepts":[{"id":"https://openalex.org/C2777016524","wikidata":"https://www.wikidata.org/wiki/Q630552","display_name":"Retinitis","level":4,"score":0.9380065202713013},{"id":"https://openalex.org/C2777324356","wikidata":"https://www.wikidata.org/wiki/Q4271835","display_name":"Cytomegalovirus retinitis","level":5,"score":0.8483572006225586},{"id":"https://openalex.org/C2777965375","wikidata":"https://www.wikidata.org/wiki/Q417640","display_name":"Ganciclovir","level":4,"score":0.8257877826690674},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.7945349216461182},{"id":"https://openalex.org/C2778257484","wikidata":"https://www.wikidata.org/wiki/Q555066","display_name":"Visual acuity","level":2,"score":0.648479163646698},{"id":"https://openalex.org/C118487528","wikidata":"https://www.wikidata.org/wiki/Q161437","display_name":"Ophthalmology","level":1,"score":0.5190635323524475},{"id":"https://openalex.org/C2776572573","wikidata":"https://www.wikidata.org/wiki/Q972514","display_name":"Optic neuritis","level":3,"score":0.5056800842285156},{"id":"https://openalex.org/C2777732132","wikidata":"https://www.wikidata.org/wiki/Q6946","display_name":"Cytomegalovirus","level":5,"score":0.45974308252334595},{"id":"https://openalex.org/C2780827179","wikidata":"https://www.wikidata.org/wiki/Q422001","display_name":"Retinal","level":2,"score":0.4586082100868225},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.4503336548805237},{"id":"https://openalex.org/C2776409557","wikidata":"https://www.wikidata.org/wiki/Q149348","display_name":"Herpesviridae","level":4,"score":0.3208957314491272},{"id":"https://openalex.org/C2779820661","wikidata":"https://www.wikidata.org/wiki/Q6929","display_name":"Human cytomegalovirus","level":3,"score":0.24408277869224548},{"id":"https://openalex.org/C2780727368","wikidata":"https://www.wikidata.org/wiki/Q1928978","display_name":"Viral disease","level":3,"score":0.15284311771392822},{"id":"https://openalex.org/C2522874641","wikidata":"https://www.wikidata.org/wiki/Q808","display_name":"Virus","level":2,"score":0.1069226861000061},{"id":"https://openalex.org/C159047783","wikidata":"https://www.wikidata.org/wiki/Q7215","display_name":"Virology","level":1,"score":0.09473651647567749},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.08584949374198914},{"id":"https://openalex.org/C2780640218","wikidata":"https://www.wikidata.org/wiki/Q8277","display_name":"Multiple sclerosis","level":2,"score":0.0648505687713623}],"mesh":[{"descriptor_ui":"D000163","descriptor_name":"Acquired Immunodeficiency Syndrome","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":true},{"descriptor_ui":"D000212","descriptor_name":"Acyclovir","qualifier_ui":"Q000031","qualifier_name":"analogs & derivatives","is_major_topic":true},{"descriptor_ui":"D000212","descriptor_name":"Acyclovir","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003586","descriptor_name":"Cytomegalovirus Infections","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009887","descriptor_name":"Ophthalmoscopy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012008","descriptor_name":"Recurrence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012173","descriptor_name":"Retinitis","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":false},{"descriptor_ui":"D012173","descriptor_name":"Retinitis","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":false},{"descriptor_ui":"D012173","descriptor_name":"Retinitis","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":true},{"descriptor_ui":"D012173","descriptor_name":"Retinitis","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D014792","descriptor_name":"Visual Acuity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015774","descriptor_name":"Ganciclovir","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.1007/bf00142691","doi":"https://doi.org/10.1007/bf00142691","is_oa":false,"landing_page_url":"https://doi.org/10.1007/bf00142691","pdf_url":null,"source":{"id":"https://openalex.org/S6331754","display_name":"Documenta Ophthalmologica","issn_l":"0012-4486","issn":["0012-4486","1573-2622"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","medline","norway-1","poland-100","russia-white-list-2"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Documenta Ophthalmologica","raw_type":"journal-article"},{"id":"pmid:2827978","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/2827978","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Documenta ophthalmologica. Advances in ophthalmology","raw_type":"Case Reports"},{"id":"pmh:oai:pure.rug.nl:openaire_cris_publications/f0e5a0ff-703a-4ec4-a90a-2e666a892b15","doi":null,"is_oa":false,"landing_page_url":"https://hdl.handle.net/11370/f0e5a0ff-703a-4ec4-a90a-2e666a892b15","pdf_url":null,"source":{"id":"https://openalex.org/S4306400420","display_name":"University of Groningen research database (University of Groningen / Centre for Information Technology)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I169381384","host_organization_name":"University of Groningen","host_organization_lineage":["https://openalex.org/I169381384"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"HOOYMANS, JMM, SPRENGER, HG & WEITS, J 1987, 'TREATMENT OF CYTOMEGALO-VIRUS RETINITIS WITH DHPG IN A PATIENT WITH AIDS', Documenta ophthalmologica, vol. 67, no. 1-2, pp. 5-12.","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:rug:oai:pure.rug.nl:publications/f0e5a0ff-703a-4ec4-a90a-2e666a892b15","doi":null,"is_oa":false,"landing_page_url":"https://research.rug.nl/en/publications/f0e5a0ff-703a-4ec4-a90a-2e666a892b15","pdf_url":null,"source":{"id":"https://openalex.org/S4306400420","display_name":"University of Groningen research database (University of Groningen / Centre for Information Technology)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I169381384","host_organization_name":"University of Groningen","host_organization_lineage":["https://openalex.org/I169381384"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Documenta ophthalmologica, 67(1-2), 5 - 12","raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":1.0}],"study_designs":[{"id":"https://openalex.org/study-designs/case-report","display_name":"Case Report"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":9,"referenced_works":["https://openalex.org/W1970970325","https://openalex.org/W1981156436","https://openalex.org/W2006908517","https://openalex.org/W2011912116","https://openalex.org/W2040526183","https://openalex.org/W2090916141","https://openalex.org/W2095729328","https://openalex.org/W2148655606","https://openalex.org/W2616647315"],"related_works":["https://openalex.org/W1965555864","https://openalex.org/W2421344733","https://openalex.org/W2462486762","https://openalex.org/W2055216639","https://openalex.org/W1976815486","https://openalex.org/W2473366050","https://openalex.org/W119059565","https://openalex.org/W2063732162","https://openalex.org/W1992943611","https://openalex.org/W2090916141"],"abstract_inverted_index":null,"counts_by_year":[{"year":2017,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}