{"id":"https://openalex.org/W1966648772","doi":"https://doi.org/10.1006/bbrc.1998.9116","title":"Stimulatory Effect of Lipoprotein (a) on Proliferation of Human Mesangial Cells: Role of Lipoprotein (a) in Renal Disease","display_name":"Stimulatory Effect of Lipoprotein (a) on Proliferation of Human Mesangial Cells: Role of Lipoprotein (a) in Renal Disease","publication_year":1998,"publication_date":"1998-08-01","ids":{"openalex":"https://openalex.org/W1966648772","doi":"https://doi.org/10.1006/bbrc.1998.9116","mag":"1966648772","pmid":"https://pubmed.ncbi.nlm.nih.gov/9712693"},"language":"en","primary_location":{"id":"doi:10.1006/bbrc.1998.9116","doi":"https://doi.org/10.1006/bbrc.1998.9116","is_oa":false,"landing_page_url":"https://doi.org/10.1006/bbrc.1998.9116","pdf_url":null,"source":{"id":"https://openalex.org/S151589183","display_name":"Biochemical and Biophysical Research Communications","issn_l":"0006-291X","issn":["0006-291X","1090-2104"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biochemical and Biophysical Research Communications","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5025005882","display_name":"Ryuichi Morishita","orcid":"https://orcid.org/0000-0002-8855-0730","observed_orcids":["https://orcid.org/0000-0002-8855-0730"]},"institutions":[{"id":"https://openalex.org/I98285908","display_name":"The University of Osaka","ror":"https://ror.org/035t8zc32","country_code":"JP","type":"education","lineage":["https://openalex.org/I98285908"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Ryuichi Morishita","raw_affiliation_strings":["Department of Geriatric Medicine, Osaka University Medical School, Suita, 565, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Geriatric Medicine, Osaka University Medical School, Suita, 565, Japan","institution_ids":["https://openalex.org/I98285908"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5062577479","display_name":"Kei Yamamoto","orcid":"https://orcid.org/0000-0002-3220-9779","observed_orcids":["https://orcid.org/0000-0002-3220-9779"]},"institutions":[{"id":"https://openalex.org/I98285908","display_name":"The University of Osaka","ror":"https://ror.org/035t8zc32","country_code":"JP","type":"education","lineage":["https://openalex.org/I98285908"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Kei Yamamoto","raw_affiliation_strings":["Department of Geriatric Medicine, Osaka University Medical School, Suita, 565, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Geriatric Medicine, Osaka University Medical School, Suita, 565, Japan","institution_ids":["https://openalex.org/I98285908"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5016502070","display_name":"Shingo Yamada","orcid":"https://orcid.org/0000-0001-9250-6241","observed_orcids":["https://orcid.org/0000-0001-9250-6241"]},"institutions":[{"id":"https://openalex.org/I4387152237","display_name":"Shino-Test Corporation","ror":"https://ror.org/02zfbyq93","country_code":"JP","type":"company","lineage":["https://openalex.org/I4387152237"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Shingo Yamada","raw_affiliation_strings":["Shinotest Co. Tokyo, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Shinotest Co. Tokyo, Japan","institution_ids":["https://openalex.org/I4387152237"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108410596","display_name":"Hidetsugu Matsushita","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I98285908","display_name":"The University of Osaka","ror":"https://ror.org/035t8zc32","country_code":"JP","type":"education","lineage":["https://openalex.org/I98285908"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Hidetsugu Matsushita","raw_affiliation_strings":["Department of Geriatric Medicine, Osaka University Medical School, Suita, 565, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Geriatric Medicine, Osaka University Medical School, Suita, 565, Japan","institution_ids":["https://openalex.org/I98285908"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5057547460","display_name":"Naruya Tomita","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I98285908","display_name":"The University of Osaka","ror":"https://ror.org/035t8zc32","country_code":"JP","type":"education","lineage":["https://openalex.org/I98285908"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Naruya Tomita","raw_affiliation_strings":["Department of Geriatric Medicine, Osaka University Medical School, Suita, 565, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Geriatric Medicine, Osaka University Medical School, Suita, 565, Japan","institution_ids":["https://openalex.org/I98285908"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5046737105","display_name":"Ikunosuke Sakurabayashi","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I146500386","display_name":"Jichi Medical University","ror":"https://ror.org/010hz0g26","country_code":"JP","type":"education","lineage":["https://openalex.org/I146500386"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Ikunosuke Sakurabayashi","raw_affiliation_strings":["Ohmiya Medical Center, Jichi Medical School, Omiya, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Ohmiya Medical Center, Jichi Medical School, Omiya, Japan","institution_ids":["https://openalex.org/I146500386"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5102026777","display_name":"Yasufumi Kaneda","orcid":"https://orcid.org/0009-0009-6106-5434","observed_orcids":["https://orcid.org/0009-0009-6106-5434"]},"institutions":[{"id":"https://openalex.org/I98285908","display_name":"The University of Osaka","ror":"https://ror.org/035t8zc32","country_code":"JP","type":"education","lineage":["https://openalex.org/I98285908"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Yasufumi Kaneda","raw_affiliation_strings":["Institute for Molecular and Cellular Biology, Osaka University Medical School, Suita, 565, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute for Molecular and Cellular Biology, Osaka University Medical School, Suita, 565, Japan","institution_ids":["https://openalex.org/I98285908"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111581661","display_name":"Atsushi Moriguchi","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I98285908","display_name":"The University of Osaka","ror":"https://ror.org/035t8zc32","country_code":"JP","type":"education","lineage":["https://openalex.org/I98285908"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Atsushi Moriguchi","raw_affiliation_strings":["Department of Geriatric Medicine, Osaka University Medical School, Suita, 565, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Geriatric Medicine, Osaka University Medical School, Suita, 565, Japan","institution_ids":["https://openalex.org/I98285908"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111653520","display_name":"Jitsuo Higaki","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I98285908","display_name":"The University of Osaka","ror":"https://ror.org/035t8zc32","country_code":"JP","type":"education","lineage":["https://openalex.org/I98285908"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Jitsuo Higaki","raw_affiliation_strings":["Department of Geriatric Medicine, Osaka University Medical School, Suita, 565, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Geriatric Medicine, Osaka University Medical School, Suita, 565, Japan","institution_ids":["https://openalex.org/I98285908"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5078822609","display_name":"Toshio Ogihara","orcid":"https://orcid.org/0000-0002-7119-7192","observed_orcids":["https://orcid.org/0000-0002-7119-7192"]},"institutions":[{"id":"https://openalex.org/I98285908","display_name":"The University of Osaka","ror":"https://ror.org/035t8zc32","country_code":"JP","type":"education","lineage":["https://openalex.org/I98285908"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Toshio Ogihara","raw_affiliation_strings":["Department of Geriatric Medicine, Osaka University Medical School, Suita, 565, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Geriatric Medicine, Osaka University Medical School, Suita, 565, Japan","institution_ids":["https://openalex.org/I98285908"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":3110,"currency":"USD","value_usd":3110},"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":4,"citation_normalized_percentile":{"value":0.0,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":95},"biblio":{"volume":"249","issue":"2","first_page":"313","last_page":"320"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11029","display_name":"Renal Diseases and Glomerulopathies","score":0.760699987411499,"subfield":{"id":"https://openalex.org/subfields/2727","display_name":"Nephrology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11029","display_name":"Renal Diseases and Glomerulopathies","score":0.760699987411499,"subfield":{"id":"https://openalex.org/subfields/2727","display_name":"Nephrology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10408","display_name":"Chronic Kidney Disease and Diabetes","score":0.20010000467300415,"subfield":{"id":"https://openalex.org/subfields/2727","display_name":"Nephrology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10394","display_name":"Lipoproteins and Cardiovascular Health","score":0.010300000198185444,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/lipoprotein-a","display_name":"lipoprotein(a)","score":0.890999972820282},{"id":"https://openalex.org/keywords/mesangial-proliferation","display_name":"mesangial cell proliferation","score":0.8870000243186951},{"id":"https://openalex.org/keywords/apolipoprotein-a","display_name":"apolipoprotein(a)","score":0.7720000147819519},{"id":"https://openalex.org/keywords/apolipoprotein-b","display_name":"apolipoprotein B","score":0.7789999842643738},{"id":"https://openalex.org/keywords/low-density-lipoprotein","display_name":"low-density lipoprotein","score":0.6480000019073486},{"id":"https://openalex.org/keywords/transforming-growth-factor-beta","display_name":"TGF-beta","score":0.8429999947547913},{"id":"https://openalex.org/keywords/glomerular-injury","display_name":"glomerular injury","score":0.9319999814033508},{"id":"https://openalex.org/keywords/kidney-disease","display_name":"kidney disease","score":0.9729999899864197},{"id":"https://openalex.org/keywords/hepatoma-cells","display_name":"hepatoma cells","score":0.5889999866485596},{"id":"https://openalex.org/keywords/cell-growth-stimulation","display_name":"cell growth stimulation","score":0.6140000224113464}],"concepts":[{"id":"https://openalex.org/C2776104379","wikidata":"https://www.wikidata.org/wiki/Q21112670","display_name":"Lipoprotein(a)","level":4,"score":0.6552556753158569},{"id":"https://openalex.org/C2779131090","wikidata":"https://www.wikidata.org/wiki/Q3331086","display_name":"Mesangial cell","level":3,"score":0.6547457575798035},{"id":"https://openalex.org/C2780072125","wikidata":"https://www.wikidata.org/wiki/Q28350","display_name":"Lipoprotein","level":3,"score":0.6303843259811401},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.5261328220367432},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.5210956335067749},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.4595798850059509},{"id":"https://openalex.org/C174782155","wikidata":"https://www.wikidata.org/wiki/Q18032613","display_name":"Low-density lipoprotein receptor-related protein 8","level":5,"score":0.456748366355896},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.34711146354675293},{"id":"https://openalex.org/C2778163477","wikidata":"https://www.wikidata.org/wiki/Q43656","display_name":"Cholesterol","level":2,"score":0.25678521394729614},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.2497316300868988},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.24424663186073303},{"id":"https://openalex.org/C8243546","wikidata":"https://www.wikidata.org/wiki/Q419074","display_name":"Very low-density lipoprotein","level":4,"score":0.18999925255775452},{"id":"https://openalex.org/C2780091579","wikidata":"https://www.wikidata.org/wiki/Q9377","display_name":"Kidney","level":2,"score":0.18484365940093994}],"mesh":[{"descriptor_ui":"D001054","descriptor_name":"Apolipoproteins A","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D001055","descriptor_name":"Apolipoproteins B","qualifier_ui":"Q000096","qualifier_name":"biosynthesis","is_major_topic":false},{"descriptor_ui":"D002455","descriptor_name":"Cell Division","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D002460","descriptor_name":"Cell Line","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005920","descriptor_name":"Glomerular Mesangium","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":true},{"descriptor_ui":"D005920","descriptor_name":"Glomerular Mesangium","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D006528","descriptor_name":"Carcinoma, Hepatocellular","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007674","descriptor_name":"Kidney Diseases","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":true},{"descriptor_ui":"D008113","descriptor_name":"Liver Neoplasms","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D012333","descriptor_name":"RNA, Messenger","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D014162","descriptor_name":"Transfection","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014407","descriptor_name":"Tumor Cells, Cultured","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015153","descriptor_name":"Blotting, Western","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015870","descriptor_name":"Gene Expression","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017077","descriptor_name":"Culture Media, Conditioned","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017270","descriptor_name":"Lipoprotein(a)","qualifier_ui":"Q000096","qualifier_name":"biosynthesis","is_major_topic":false},{"descriptor_ui":"D017270","descriptor_name":"Lipoprotein(a)","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1006/bbrc.1998.9116","doi":"https://doi.org/10.1006/bbrc.1998.9116","is_oa":false,"landing_page_url":"https://doi.org/10.1006/bbrc.1998.9116","pdf_url":null,"source":{"id":"https://openalex.org/S151589183","display_name":"Biochemical and Biophysical Research Communications","issn_l":"0006-291X","issn":["0006-291X","1090-2104"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biochemical and Biophysical Research Communications","raw_type":"journal-article"},{"id":"pmid:9712693","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/9712693","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biochemical and biophysical research communications","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.98580002784729}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":32,"referenced_works":["https://openalex.org/W1515525226","https://openalex.org/W1976485306","https://openalex.org/W1983055162","https://openalex.org/W1989815448","https://openalex.org/W1994273046","https://openalex.org/W1995700570","https://openalex.org/W1997320114","https://openalex.org/W1998010052","https://openalex.org/W2001324205","https://openalex.org/W2001691760","https://openalex.org/W2001907249","https://openalex.org/W2005917979","https://openalex.org/W2007775733","https://openalex.org/W2013525819","https://openalex.org/W2025235579","https://openalex.org/W2025563293","https://openalex.org/W2029442803","https://openalex.org/W2032003381","https://openalex.org/W2034457606","https://openalex.org/W2036170644","https://openalex.org/W2042042415","https://openalex.org/W2047724621","https://openalex.org/W2067318301","https://openalex.org/W2068112302","https://openalex.org/W2085179336","https://openalex.org/W2090464247","https://openalex.org/W2113106232","https://openalex.org/W2152173653","https://openalex.org/W2158046255","https://openalex.org/W2168837119","https://openalex.org/W2169074593","https://openalex.org/W2304929865"],"related_works":["https://openalex.org/W2032003381","https://openalex.org/W2120196791","https://openalex.org/W2065024501","https://openalex.org/W272724206","https://openalex.org/W2589477377","https://openalex.org/W2047902367","https://openalex.org/W2073503826","https://openalex.org/W1975573054","https://openalex.org/W1980930264","https://openalex.org/W1984426784"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":1},{"year":2019,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}