{"id":"https://openalex.org/W1966647169","doi":"https://doi.org/10.1117/12.384223","title":"Magnification-corrected optical image splitting for simultaneous multiplanar acquisition","display_name":"Magnification-corrected optical image splitting for simultaneous multiplanar acquisition","publication_year":2000,"publication_date":"2000-04-27","ids":{"openalex":"https://openalex.org/W1966647169","doi":"https://doi.org/10.1117/12.384223","mag":"1966647169"},"language":"en","primary_location":{"id":"doi:10.1117/12.384223","doi":"https://doi.org/10.1117/12.384223","is_oa":false,"landing_page_url":"https://doi.org/10.1117/12.384223","pdf_url":null,"source":{"id":"https://openalex.org/S183492911","display_name":"Proceedings of SPIE, the International Society for Optical Engineering/Proceedings of SPIE","issn_l":"0277-786X","issn":["0277-786X","1996-756X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","norway-1"],"host_organization":"https://openalex.org/P4310315543","host_organization_name":"SPIE","host_organization_lineage":["https://openalex.org/P4310315543"],"host_organization_lineage_names":["SPIE"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"SPIE Proceedings","raw_type":"proceedings-article"},"volume":null,"type":"conference-paper","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5055091635","display_name":"Lam K. Nguyen","orcid":"https://orcid.org/0009-0009-1595-2964","observed_orcids":["https://orcid.org/0009-0009-1595-2964"]},"institutions":[{"id":"https://openalex.org/I36258959","display_name":"University of California San Diego","ror":"https://ror.org/0168r3w48","country_code":"US","type":"education","lineage":["https://openalex.org/I36258959"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Lam K. Nguyen","raw_affiliation_strings":["Univ. of California/San Diego (United States)","University of California, San Diego (United States)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Univ. of California/San Diego (United States)","institution_ids":["https://openalex.org/I36258959"]},{"raw_affiliation_string":"University of California, San Diego (United States)","institution_ids":["https://openalex.org/I36258959"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5079719865","display_name":"Miguel E. Bravo-Zanoguera","orcid":"https://orcid.org/0000-0003-1227-9726","observed_orcids":["https://orcid.org/0000-0003-1227-9726"]},"institutions":[{"id":"https://openalex.org/I36258959","display_name":"University of California San Diego","ror":"https://ror.org/0168r3w48","country_code":"US","type":"education","lineage":["https://openalex.org/I36258959"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Miguel E. Bravo-Zanoguera","raw_affiliation_strings":["Univ. of California/San Diego and Univ. Autonoma de Baja California (United States)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Univ. of California/San Diego and Univ. Autonoma de Baja California (United States)","institution_ids":["https://openalex.org/I36258959"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5087002885","display_name":"Albert L. Kellner","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I36258959","display_name":"University of California San Diego","ror":"https://ror.org/0168r3w48","country_code":"US","type":"education","lineage":["https://openalex.org/I36258959"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Albert L. Kellner","raw_affiliation_strings":["Univ. of California/San Diego (United States)","University of California, San Diego (United States)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Univ. of California/San Diego (United States)","institution_ids":["https://openalex.org/I36258959"]},{"raw_affiliation_string":"University of California, San Diego (United States)","institution_ids":["https://openalex.org/I36258959"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5113640496","display_name":"Jeffrey H. Price","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I36258959","display_name":"University of California San Diego","ror":"https://ror.org/0168r3w48","country_code":"US","type":"education","lineage":["https://openalex.org/I36258959"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jeffrey H. Price","raw_affiliation_strings":["Univ. of California/San Diego (United States)","University of California, San Diego (United States)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Univ. of California/San Diego (United States)","institution_ids":["https://openalex.org/I36258959"]},{"raw_affiliation_string":"University of California, San Diego (United States)","institution_ids":["https://openalex.org/I36258959"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I36258959"],"apc_list":null,"apc_paid":null,"fwci":0.972,"has_fulltext":false,"cited_by_count":7,"citation_normalized_percentile":{"value":0.70515464,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":93},"biblio":{"volume":"3921","issue":null,"first_page":"31","last_page":"40"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T13114","display_name":"Image Processing Techniques and Applications","score":0.7627000212669373,"subfield":{"id":"https://openalex.org/subfields/2214","display_name":"Media Technology"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T13114","display_name":"Image Processing Techniques and Applications","score":0.7627000212669373,"subfield":{"id":"https://openalex.org/subfields/2214","display_name":"Media Technology"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10540","display_name":"Advanced Fluorescence Microscopy Techniques","score":0.058800000697374344,"subfield":{"id":"https://openalex.org/subfields/1304","display_name":"Biophysics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11992","display_name":"CCD and CMOS Imaging Sensors","score":0.050999999046325684,"subfield":{"id":"https://openalex.org/subfields/2208","display_name":"Electrical and Electronic Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/image-cytometry","display_name":"image cytometry","score":0.875},{"id":"https://openalex.org/keywords/autofocus","display_name":"autofocus","score":0.6970000267028809},{"id":"https://openalex.org/keywords/magnification-correction","display_name":"magnification correction","score":0.8199999928474426},{"id":"https://openalex.org/keywords/beam-splitter","display_name":"beam splitter","score":0.7540000081062317},{"id":"https://openalex.org/keywords/ccd-detector","display_name":"CCD detector","score":0.5199999809265137},{"id":"https://openalex.org/keywords/high-speed-scanning","display_name":"high-speed scanning","score":0.5899999737739563},{"id":"https://openalex.org/keywords/3d-imaging","display_name":"3D imaging","score":0.7599999904632568},{"id":"https://openalex.org/keywords/depth-of-field","display_name":"depth of field","score":0.6489999890327454},{"id":"https://openalex.org/keywords/fluorescence-microscopy","display_name":"fluorescence microscopy","score":0.36800000071525574}],"concepts":[{"id":"https://openalex.org/C103764139","wikidata":"https://www.wikidata.org/wiki/Q210008","display_name":"Autofocus","level":3,"score":0.8737547397613525},{"id":"https://openalex.org/C4144372","wikidata":"https://www.wikidata.org/wiki/Q675287","display_name":"Magnification","level":2,"score":0.7248069047927856},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.5993759036064148},{"id":"https://openalex.org/C31972630","wikidata":"https://www.wikidata.org/wiki/Q844240","display_name":"Computer vision","level":1,"score":0.5615844130516052},{"id":"https://openalex.org/C120665830","wikidata":"https://www.wikidata.org/wiki/Q14620","display_name":"Optics","level":1,"score":0.5474324226379395},{"id":"https://openalex.org/C134786449","wikidata":"https://www.wikidata.org/wiki/Q3391255","display_name":"Planar","level":2,"score":0.5361554026603699},{"id":"https://openalex.org/C78336883","wikidata":"https://www.wikidata.org/wiki/Q4779385","display_name":"Aperture (computer memory)","level":2,"score":0.5352497696876526},{"id":"https://openalex.org/C159108749","wikidata":"https://www.wikidata.org/wiki/Q898896","display_name":"Numerical aperture","level":3,"score":0.4953209459781647},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.44692087173461914},{"id":"https://openalex.org/C67649825","wikidata":"https://www.wikidata.org/wiki/Q196538","display_name":"Microscope","level":2,"score":0.44420522451400757},{"id":"https://openalex.org/C205372480","wikidata":"https://www.wikidata.org/wiki/Q210521","display_name":"Image resolution","level":2,"score":0.4207388162612915},{"id":"https://openalex.org/C192209626","wikidata":"https://www.wikidata.org/wiki/Q190909","display_name":"Focus (optics)","level":2,"score":0.37107276916503906},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.23636922240257263},{"id":"https://openalex.org/C121684516","wikidata":"https://www.wikidata.org/wiki/Q7600677","display_name":"Computer graphics (images)","level":1,"score":0.18912211060523987},{"id":"https://openalex.org/C24890656","wikidata":"https://www.wikidata.org/wiki/Q82811","display_name":"Acoustics","level":1,"score":0.0},{"id":"https://openalex.org/C6260449","wikidata":"https://www.wikidata.org/wiki/Q41364","display_name":"Wavelength","level":2,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1117/12.384223","doi":"https://doi.org/10.1117/12.384223","is_oa":false,"landing_page_url":"https://doi.org/10.1117/12.384223","pdf_url":null,"source":{"id":"https://openalex.org/S183492911","display_name":"Proceedings of SPIE, the International Society for Optical Engineering/Proceedings of SPIE","issn_l":"0277-786X","issn":["0277-786X","1996-756X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","norway-1"],"host_organization":"https://openalex.org/P4310315543","host_organization_name":"SPIE","host_organization_lineage":["https://openalex.org/P4310315543"],"host_organization_lineage_names":["SPIE"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"SPIE Proceedings","raw_type":"proceedings-article"}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2044309016","https://openalex.org/W2008075069","https://openalex.org/W4253918641","https://openalex.org/W1992075200","https://openalex.org/W2015019909","https://openalex.org/W2897192958","https://openalex.org/W2408620849","https://openalex.org/W2090575891","https://openalex.org/W2120233137","https://openalex.org/W2893273782"],"abstract_inverted_index":{"Simultaneous":[0],"multi":[1,152,203],"planar":[2,153,204],"microscope":[3],"imaging":[4,169],"enables":[5,180],"parallel":[6,202],"computation":[7],"of":[8,47,50,67,110,117,134,140,182,210],"autofocus":[9,126],"for":[10,58,128,150,213],"high-sped":[11],"image":[12,15,35,106],"cytometry.":[13],"Although":[14],"cytometry":[16,36],"exhibits":[17],"many":[18],"potential":[19],"advantages":[20],"over":[21],"flow":[22],"cytometry,":[23],"substantially":[24],"slower":[25],"speed":[26,113],"has":[27],"limited":[28],"use":[29],"to":[30,189],"fewer":[31],"applications.":[32],"In":[33],"commercial":[34],"instruments,":[37],"long":[38],"scanning":[39],"times":[40],"have":[41],"typically":[42],"been":[43],"circumvented":[44],"by":[45,114],"identification":[46],"small":[48],"areas":[49],"interest":[51],"during":[52],"high":[53,62,74,199],"speed,":[54],"low":[55],"resolution":[56,75,130],"scans":[57],"subsequent":[59],"analysis":[60],"at":[61,73,84],"resolution.":[63],"This":[64,158,175],"two-pass":[65],"strategy":[66],"analyzing":[68],"only":[69],"a":[70,77,141,197],"few":[71],"cells":[72],"is":[76,108,136,196],"disadvantage":[78],"and":[79,155,164,173,217],"often":[80],"cannot":[81],"be":[82],"used":[83],"all":[85],"where":[86,132],"dim":[87],"fluorescence":[88],"demands":[89],"higher":[90,129],"numerical":[91],"aperture":[92],"(NA)":[93],"objectives.":[94],"Continuous":[95],"stage":[96],"motion":[97],"synchronized":[98],"with":[99,171],"line":[100],"array":[101,209],"or":[102,119],"time-delay-and-integrate":[103],"(TDI)":[104],"CCD":[105,211],"acquisition":[107,154,205],"capable":[109],"increasing":[111],"scan":[112],"an":[115,147,208],"order":[116],"magnitude":[118],"more,":[120],"but":[121],"until":[122],"recently":[123],"lacked":[124],"the":[125,138,190],"required":[127],"objectives":[131],"depth":[133],"field":[135],"about":[137],"thickness":[139],"cell":[142],"monolayer.":[143],"Here":[144],"we":[145],"describe":[146],"improved":[148],"design":[149,178],"simultaneous":[151],"on-the-fly":[156],"autofocus.":[157],"new":[159,176],"system":[160],"replaces":[161],"more":[162],"complicated":[163],"less":[165],"light":[166],"efficient":[167],"fiberoptic":[168,192],"bundles":[170],"beamsplitters":[172],"mirrors.":[174],"image-splitting":[177],"also":[179],"addition":[181],"magnification":[183],"correction":[184],"optics":[185],"not":[186],"easily":[187],"added":[188],"earlier":[191],"version.":[193],"The":[194],"result":[195],"simplified,":[198],"sensitivity,":[200],"magnification-matched,":[201],"module":[206],"containing":[207],"sensors":[212],"high-speed":[214],"focus":[215],"tracking":[216],"3D":[218],"imaging.":[219]},"counts_by_year":[{"year":2017,"cited_by_count":1}],"updated_date":"2026-08-21T09:56:20.448147","created_date":"2016-06-24T00:00:00"}