{"id":"https://openalex.org/W1966392015","doi":"https://doi.org/10.1016/s0120-5633(12)70127-4","title":"Actividad de la prote\u00edna transportadora de \u00e9steres de colesterol. Polimorfismos del gen en pacientes colombianos con enfermedad coronaria","display_name":"Actividad de la prote\u00edna transportadora de \u00e9steres de colesterol. Polimorfismos del gen en pacientes colombianos con enfermedad coronaria","publication_year":2012,"publication_date":"2012-07-01","ids":{"openalex":"https://openalex.org/W1966392015","doi":"https://doi.org/10.1016/s0120-5633(12)70127-4","mag":"1966392015"},"language":"es","primary_location":{"id":"doi:10.1016/s0120-5633(12)70127-4","doi":"https://doi.org/10.1016/s0120-5633(12)70127-4","is_oa":true,"landing_page_url":"https://doi.org/10.1016/s0120-5633(12)70127-4","pdf_url":null,"source":{"id":"https://openalex.org/S2898113767","display_name":"Revista Colombiana de Cardiolog\u00eda","issn_l":"0120-5633","issn":["0120-5633","2357-3260"],"is_oa":true,"is_in_doaj":true,"is_core":false,"listed_in":["doaj","poland-20","publindex-c","russia-white-list-4","scielo"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Revista Colombiana de Cardiolog\u00eda","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj"],"open_access":{"is_oa":true,"oa_status":"diamond","oa_url":"https://doi.org/10.1016/s0120-5633(12)70127-4","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5103087143","display_name":"Alejandra Mar\u00eda Giraldo","orcid":"https://orcid.org/0000-0002-2084-4505","observed_orcids":["https://orcid.org/0000-0002-2084-4505"]},"institutions":[{"id":"https://openalex.org/I135437138","display_name":"Universidad del Quind\u00edo","ror":"https://ror.org/01358s213","country_code":"CO","type":"education","lineage":["https://openalex.org/I135437138"]}],"countries":["CO"],"is_corresponding":false,"raw_author_name":"Alejandra M. Giraldo","raw_affiliation_strings":["Grupo de Investigaci\u00f3n en Enfermedades Cardiovasculares y Metab\u00f3licas. Facultad de Ciencias de la Salud. Universidad del Quind\u00edo. Armenia-Quind\u00edo, Colombia","Programa de Licenciatura en Biolog\u00eda y Educaci\u00f3n ambiental. Facultad de Educaci\u00f3n. Universidad del Quind\u00edo. Armenia-Quind\u00edo, Colombia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Grupo de Investigaci\u00f3n en Enfermedades Cardiovasculares y Metab\u00f3licas. Facultad de Ciencias de la Salud. Universidad del Quind\u00edo. Armenia-Quind\u00edo, Colombia","institution_ids":["https://openalex.org/I135437138"]},{"raw_affiliation_string":"Programa de Licenciatura en Biolog\u00eda y Educaci\u00f3n ambiental. Facultad de Educaci\u00f3n. Universidad del Quind\u00edo. Armenia-Quind\u00edo, Colombia","institution_ids":["https://openalex.org/I135437138"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112078888","display_name":"Nelsy Loango","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I135437138","display_name":"Universidad del Quind\u00edo","ror":"https://ror.org/01358s213","country_code":"CO","type":"education","lineage":["https://openalex.org/I135437138"]}],"countries":["CO"],"is_corresponding":false,"raw_author_name":"Nelsy Loango","raw_affiliation_strings":["Grupo de Investigaci\u00f3n en Enfermedades Cardiovasculares y Metab\u00f3licas. Facultad de Ciencias de la Salud. Universidad del Quind\u00edo. Armenia-Quind\u00edo, Colombia","Programa de Biolog\u00eda. Facultad de Ciencias B\u00e1sicas y Tecnolog\u00edas. Universidad del Quind\u00edo. Armenia-Quind\u00edo, Colombia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Grupo de Investigaci\u00f3n en Enfermedades Cardiovasculares y Metab\u00f3licas. Facultad de Ciencias de la Salud. Universidad del Quind\u00edo. Armenia-Quind\u00edo, Colombia","institution_ids":["https://openalex.org/I135437138"]},{"raw_affiliation_string":"Programa de Biolog\u00eda. Facultad de Ciencias B\u00e1sicas y Tecnolog\u00edas. Universidad del Quind\u00edo. Armenia-Quind\u00edo, Colombia","institution_ids":["https://openalex.org/I135437138"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111002116","display_name":"Hugo Casta\u00f1o","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I135437138","display_name":"Universidad del Quind\u00edo","ror":"https://ror.org/01358s213","country_code":"CO","type":"education","lineage":["https://openalex.org/I135437138"]}],"countries":["CO"],"is_corresponding":false,"raw_author_name":"Hugo Casta\u00f1o","raw_affiliation_strings":["Grupo de Investigaci\u00f3n en Enfermedades Cardiovasculares y Metab\u00f3licas. Facultad de Ciencias de la Salud. Universidad del Quind\u00edo. Armenia-Quind\u00edo, Colombia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Grupo de Investigaci\u00f3n en Enfermedades Cardiovasculares y Metab\u00f3licas. Facultad de Ciencias de la Salud. Universidad del Quind\u00edo. Armenia-Quind\u00edo, Colombia","institution_ids":["https://openalex.org/I135437138"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5088566822","display_name":"Patricia Land\u00e1zuri","orcid":"https://orcid.org/0000-0002-6893-1405","observed_orcids":["https://orcid.org/0000-0002-6893-1405"]},"institutions":[{"id":"https://openalex.org/I135437138","display_name":"Universidad del Quind\u00edo","ror":"https://ror.org/01358s213","country_code":"CO","type":"education","lineage":["https://openalex.org/I135437138"]}],"countries":["CO"],"is_corresponding":true,"raw_author_name":"Patricia Land\u00e1zuri","raw_affiliation_strings":["Grupo de Investigaci\u00f3n en Enfermedades Cardiovasculares y Metab\u00f3licas. Facultad de Ciencias de la Salud. Universidad del Quind\u00edo. Armenia-Quind\u00edo, Colombia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Grupo de Investigaci\u00f3n en Enfermedades Cardiovasculares y Metab\u00f3licas. Facultad de Ciencias de la Salud. Universidad del Quind\u00edo. Armenia-Quind\u00edo, Colombia","institution_ids":["https://openalex.org/I135437138"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5088566822"],"corresponding_institution_ids":["https://openalex.org/I135437138"],"apc_list":null,"apc_paid":null,"fwci":0.391,"has_fulltext":false,"cited_by_count":4,"citation_normalized_percentile":{"value":0.55288853,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":95},"biblio":{"volume":"19","issue":"4","first_page":"172","last_page":"179"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12975","display_name":"Paraoxonase enzyme and polymorphisms","score":0.32199999690055847,"subfield":{"id":"https://openalex.org/subfields/1308","display_name":"Clinical Biochemistry"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T12975","display_name":"Paraoxonase enzyme and polymorphisms","score":0.32199999690055847,"subfield":{"id":"https://openalex.org/subfields/1308","display_name":"Clinical Biochemistry"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10394","display_name":"Lipoproteins and Cardiovascular Health","score":0.23100000619888306,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10261","display_name":"Genetic Associations and Epidemiology","score":0.2249000072479248,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/cholesteryl-ester-transfer-protein","display_name":"cholesteryl ester transfer protein","score":0.9860000014305115},{"id":"https://openalex.org/keywords/cetp-gene-polymorphisms","display_name":"CETP gene polymorphisms","score":0.890999972820282},{"id":"https://openalex.org/keywords/taqib-polymorphism","display_name":"TaqIB polymorphism","score":0.8560000061988831},{"id":"https://openalex.org/keywords/mspi-polymorphism","display_name":"MspI polymorphism","score":0.996999979019165},{"id":"https://openalex.org/keywords/rsai-polymorphism","display_name":"RsaI polymorphism","score":0.996999979019165},{"id":"https://openalex.org/keywords/coronary-artery-disease","display_name":"coronary artery disease","score":0.7990000247955322},{"id":"https://openalex.org/keywords/coronary-artery-obstruction","display_name":"coronary artery obstruction","score":0.8500000238418579},{"id":"https://openalex.org/keywords/hdl-cholesterol","display_name":"HDL cholesterol","score":0.7239999771118164},{"id":"https://openalex.org/keywords/enzyme-activity","display_name":"enzyme activity","score":0.6980000138282776},{"id":"https://openalex.org/keywords/colombian-patients","display_name":"Colombian patients","score":0.734000027179718},{"id":"https://openalex.org/keywords/genetic-association","display_name":"genetic association","score":0.7239999771118164},{"id":"https://openalex.org/keywords/haplotypes","display_name":"haplotypes","score":0.6740000247955322},{"id":"https://openalex.org/keywords/coronary-angiography","display_name":"coronary angiography","score":0.45100000500679016}],"concepts":[{"id":"https://openalex.org/C153911025","wikidata":"https://www.wikidata.org/wiki/Q7202","display_name":"Molecular biology","level":1,"score":0.40790289640426636},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.3771839439868927},{"id":"https://openalex.org/C15708023","wikidata":"https://www.wikidata.org/wiki/Q80083","display_name":"Humanities","level":1,"score":0.37505555152893066},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.16201716661453247},{"id":"https://openalex.org/C138885662","wikidata":"https://www.wikidata.org/wiki/Q5891","display_name":"Philosophy","level":0,"score":0.057412803173065186}],"mesh":[],"locations_count":4,"locations":[{"id":"doi:10.1016/s0120-5633(12)70127-4","doi":"https://doi.org/10.1016/s0120-5633(12)70127-4","is_oa":true,"landing_page_url":"https://doi.org/10.1016/s0120-5633(12)70127-4","pdf_url":null,"source":{"id":"https://openalex.org/S2898113767","display_name":"Revista Colombiana de Cardiolog\u00eda","issn_l":"0120-5633","issn":["0120-5633","2357-3260"],"is_oa":true,"is_in_doaj":true,"is_core":false,"listed_in":["doaj","poland-20","publindex-c","russia-white-list-4","scielo"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Revista Colombiana de Cardiolog\u00eda","raw_type":"journal-article"},{"id":"pmh:oai:doaj.org/article:0d5b59c91a204f63bb1e1dbb6979f8f7","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/0d5b59c91a204f63bb1e1dbb6979f8f7","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Revista Colombiana de Cardiolog\u00eda, Vol 19, Iss 4, Pp 172-179 (2012)","raw_type":"article"},{"id":"pmh:oai:doaj.org/article:1838871c7498476abbefab97ffd9f491","doi":null,"is_oa":false,"landing_page_url":"https://doaj.org/article/1838871c7498476abbefab97ffd9f491","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Revista Colombiana de Cardiolog\u00eda, Vol 19, Iss 4, Pp 172-179 (2012)","raw_type":"article"},{"id":"mag:3209918394","doi":null,"is_oa":true,"landing_page_url":"https://www.elsevier.es/es-revista-revista-colombiana-cardiologia-203-pdf-90336379-S300","pdf_url":null,"source":{"id":"https://openalex.org/S2898113767","display_name":"Revista Colombiana de Cardiolog\u00eda","issn_l":"0120-5633","issn":["0120-5633","2357-3260"],"is_oa":true,"is_in_doaj":true,"is_core":false,"listed_in":["doaj","poland-20","publindex-c","russia-white-list-4","scielo"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":null,"is_accepted":false,"is_published":false,"raw_source_name":"Revista Colombiana de Cardiolog\u00eda","raw_type":null}],"best_oa_location":{"id":"doi:10.1016/s0120-5633(12)70127-4","doi":"https://doi.org/10.1016/s0120-5633(12)70127-4","is_oa":true,"landing_page_url":"https://doi.org/10.1016/s0120-5633(12)70127-4","pdf_url":null,"source":{"id":"https://openalex.org/S2898113767","display_name":"Revista Colombiana de Cardiolog\u00eda","issn_l":"0120-5633","issn":["0120-5633","2357-3260"],"is_oa":true,"is_in_doaj":true,"is_core":false,"listed_in":["doaj","poland-20","publindex-c","russia-white-list-4","scielo"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Revista Colombiana de Cardiolog\u00eda","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.9907000064849854,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":27,"referenced_works":["https://openalex.org/W1974879356","https://openalex.org/W2015352200","https://openalex.org/W2019865295","https://openalex.org/W2031532845","https://openalex.org/W2034259989","https://openalex.org/W2047835909","https://openalex.org/W2048442514","https://openalex.org/W2050026966","https://openalex.org/W2058536244","https://openalex.org/W2064366700","https://openalex.org/W2085265604","https://openalex.org/W2094099379","https://openalex.org/W2108556158","https://openalex.org/W2112873133","https://openalex.org/W2116404316","https://openalex.org/W2116632231","https://openalex.org/W2117622925","https://openalex.org/W2123337267","https://openalex.org/W2141782781","https://openalex.org/W2141971467","https://openalex.org/W2144625678","https://openalex.org/W2146109620","https://openalex.org/W2151720705","https://openalex.org/W2160849920","https://openalex.org/W2168210172","https://openalex.org/W2337109902","https://openalex.org/W4249825849"],"related_works":["https://openalex.org/W7017156767","https://openalex.org/W2909084689","https://openalex.org/W2134811220","https://openalex.org/W1918451759","https://openalex.org/W3209918394","https://openalex.org/W2888611292","https://openalex.org/W2588458006","https://openalex.org/W7018032305","https://openalex.org/W2373927374","https://openalex.org/W2020499871"],"abstract_inverted_index":{"la":[0,3,6,37,49,53,59,71,74,77,84,87,90,107,156,185,193,196,204,234],"literatura":[1],"relaciona":[2],"actividad":[4,50,75,88,154,194],"de":[5,9,11,24,36,43,45,61,70,76,89,155,195,217,228,242,248],"prote\u00edna":[7],"transportadora":[8],"\u00e9steres":[10],"colesterol":[12,20],"(CETP)":[13,265],"con":[14,79,101,120,132,150,253],"enfermedad":[15,54,80,254],"coronaria,":[16,55],"por":[17,105,212],"reducir":[18],"el":[19,34,40,145,151,239,246],"en":[21,33,99,114,144,148,184,219],"las":[22],"lipoprote\u00ednas":[23],"alta":[25],"densidad.":[26],"Adicionalmente,":[27],"estudios":[28],"recientes":[29],"han":[30],"identificado":[31],"variaciones":[32],"gen":[35,69],"CETP,":[38,197,426],"aunque":[39],"papel":[41],"funcional":[42],"algunas":[44],"estas":[46],"variantes":[47],"sobre":[48],"enzim\u00e1tica":[51],"y":[52,66,73,92,97,128,160,168,182,203,245],"es":[56],"desconocido.":[57],"examinar":[58],"asociaci\u00f3n":[60,85,191],"los":[62,93,112,164,179,198,215,220,243],"polimorfismos":[63,94,199,221],"TaqIB,":[64,95,222,311,334,427],"MspI":[65,96,312,335],"RsaI":[67,314,337,429,449],"del":[68,236],"CETP":[72,157,218,285,316,387,443],"enzima":[78,91],"coronaria.":[81,206,255],"se":[82,174,189,210],"evalu\u00f3":[83],"entre":[86,178,192],"RsaI,":[98],"pacientes":[100,113,229,244],"obstrucci\u00f3n":[102,121,133,205],"coronaria":[103,122,134],"documentada":[104],"angiograf\u00eda.":[106],"angiograf\u00eda":[108],"permiti\u00f3":[109],"clasificar":[110],"a":[111,451],"dos":[115],"grupos:":[116],"uno":[117],"(213":[118,355],"individuos)":[119,131],"no":[123,188,358,418],"significativa":[124,135,177],"(OC":[125,136],"<":[126],"50%)":[127],"otro":[129],"(346":[130,366],"\u2265":[137,170,399],"50%).":[138],"La":[139,153],"edad":[140],"fue":[141,158],"significantemente":[142],"mayor":[143],"\u00faltimo":[146],"grupo":[147,227],"comparaci\u00f3n":[149],"primero.":[152],"95,8":[159],"94,7":[161],"pmol/\u03bcL.h,":[162],"para":[163,225,250],"grupos":[165],"OC<":[166],"50%":[167,373,400],"OC":[169],"50%,":[171],"respectivamente.":[172],"Solo":[173],"encontr\u00f3":[175],"diferencia":[176],"alelos":[180],"M1":[181,411],"M2":[183,413],"poblaci\u00f3n":[186],"general.":[187],"hall\u00f3":[190],"TaqBI,":[200],"MspI,":[201,223,428,448],"Rsal":[202,224],"En":[207],"este":[208],"trabajo":[209],"describen":[211],"primera":[213],"vez":[214],"niveles":[216],"un":[226],"colombianos.":[230],"Se":[231],"debe":[232],"refinar":[233],"descripci\u00f3n":[235],"evento":[237],"coronario,":[238],"contexto":[240],"metab\u00f3lico":[241],"estudio":[247],"haplotipos":[249],"encontrar":[251],"relaciones":[252],"literature":[256],"links":[257],"the":[258,284,288,307,319,327,380,385,409,415,423,440,459,462,468],"activity":[259,298,321,331,388,424],"of":[260,291,293,309,349,425,453,458,465,470],"cholesteryl":[261],"ester":[262],"transfer":[263],"protein":[264],"with":[266,322,340,357,368,480],"coronary":[267,300,323,341,360,370,432,460,481],"heart":[268,301],"disease":[269,302],"by":[270,344],"lowering":[271],"cholesterol":[272],"in":[273,283,315,338,379,414,445,475],"high":[274],"density":[275],"lipoproteins.":[276],"Additionally,":[277],"recent":[278],"studies":[279],"have":[280],"identified":[281],"variations":[282],"gene,":[286,317],"although":[287],"functional":[289],"role":[290],"some":[292],"these":[294],"variants":[295],"on":[296],"enzyme":[297,320,330],"and":[299,313,318,332,336,364,391,398,412,431,467],"is":[303],"unknown.":[304],"to":[305,384,477],"examine":[306],"association":[308,328,419],"polymorphisms":[310,333,430],"disease.":[324,482],"we":[325,437],"assessed":[326],"between":[329,408,422],"patients":[339,350,466],"obstruction":[342,361,371],"documented":[343],"angiography.":[345],"angiography":[346],"allowed":[347],"classification":[348],"into":[351],"two":[352],"groups:":[353],"one":[354,365],"patients)":[356,367],"significant":[359,369],"(CO":[362],"<50%)":[363],"(\u2265":[372],"CO).":[374],"Age":[375],"was":[376,389,405,420],"significantly":[377],"higher":[378],"latter":[381],"group":[382,452],"compared":[383],"first.":[386],"95.8":[390],"94.7":[392],"pmol/\u03bcL.h":[393],"for":[394,439,450],"groups":[395],"CO":[396],"<50%":[397],"CO,":[401],"respectively.":[402],"Significant":[403],"difference":[404],"found":[406,421],"only":[407],"alleles":[410],"general":[416],"population.":[417],"obstruction.":[433],"In":[434],"this":[435],"paper":[436],"describe":[438],"first":[441],"time":[442],"levels":[444],"TaqIB":[446],"polymorphisms,":[447],"Colombian":[454],"patients.":[455],"The":[456],"description":[457],"event,":[461],"metabolic":[463],"context":[464],"study":[469],"haplotypes":[471],"must":[472],"be":[473],"improved":[474],"order":[476],"find":[478],"relations":[479]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":1},{"year":2014,"cited_by_count":1},{"year":2012,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}