{"id":"https://openalex.org/W1966303671","doi":"https://doi.org/10.1016/j.biopsych.2005.03.002","title":"Statistical Approaches to Complex Phenotypes: Evaluating Neuropsychological Endophenotypes for Attention-Deficit/Hyperactivity Disorder","display_name":"Statistical Approaches to Complex Phenotypes: Evaluating Neuropsychological Endophenotypes for Attention-Deficit/Hyperactivity Disorder","publication_year":2005,"publication_date":"2005-06-01","ids":{"openalex":"https://openalex.org/W1966303671","doi":"https://doi.org/10.1016/j.biopsych.2005.03.002","mag":"1966303671","pmid":"https://pubmed.ncbi.nlm.nih.gov/15950007"},"language":"en","primary_location":{"id":"doi:10.1016/j.biopsych.2005.03.002","doi":"https://doi.org/10.1016/j.biopsych.2005.03.002","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.biopsych.2005.03.002","pdf_url":null,"source":{"id":"https://openalex.org/S205482884","display_name":"Biological Psychiatry","issn_l":"0006-3223","issn":["0006-3223","1873-2402"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","doyens","erih-plus","jufo-3","ki-jl-2","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biological Psychiatry","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5046114119","display_name":"Irwin D. Waldman","orcid":"https://orcid.org/0000-0002-6862-1837","observed_orcids":["https://orcid.org/0000-0002-6862-1837"]},"institutions":[{"id":"https://openalex.org/I150468666","display_name":"Emory University","ror":"https://ror.org/03czfpz43","country_code":"US","type":"education","lineage":["https://openalex.org/I150468666"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Irwin D. Waldman","raw_affiliation_strings":["Department of Psychology, Emory University, Atlanta, Georgia 30322, USA. psyiw@emory.edu","Department of Psychology , Emory University , Atlanta , Georgia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Psychology, Emory University, Atlanta, Georgia 30322, USA. psyiw@emory.edu","institution_ids":["https://openalex.org/I150468666"]},{"raw_affiliation_string":"Department of Psychology , Emory University , Atlanta , Georgia","institution_ids":["https://openalex.org/I150468666"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5046114119"],"corresponding_institution_ids":["https://openalex.org/I150468666"],"apc_list":{"value":5489,"currency":"USD","value_usd":5489},"apc_paid":null,"fwci":9.6104,"has_fulltext":false,"cited_by_count":123,"citation_normalized_percentile":{"value":0.9861369,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":89,"max":99},"biblio":{"volume":"57","issue":"11","first_page":"1347","last_page":"1356"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10537","display_name":"Attention Deficit Hyperactivity Disorder","score":0.9839000105857849,"subfield":{"id":"https://openalex.org/subfields/2738","display_name":"Psychiatry and Mental health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10537","display_name":"Attention Deficit Hyperactivity Disorder","score":0.9839000105857849,"subfield":{"id":"https://openalex.org/subfields/2738","display_name":"Psychiatry and Mental health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10261","display_name":"Genetic Associations and Epidemiology","score":0.008999999612569809,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10023","display_name":"Schizophrenia research and treatment","score":0.0010000000474974513,"subfield":{"id":"https://openalex.org/subfields/2738","display_name":"Psychiatry and Mental health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/endophenotypes","display_name":"endophenotypes","score":0.9610000252723694},{"id":"https://openalex.org/keywords/attention-deficit-hyperactivity-disorder","display_name":"attention deficit hyperactivity disorder","score":0.9890000224113464},{"id":"https://openalex.org/keywords/complex-phenotypes","display_name":"complex phenotypes","score":0.7689999938011169},{"id":"https://openalex.org/keywords/candidate-genes","display_name":"candidate genes","score":0.6790000200271606},{"id":"https://openalex.org/keywords/dopamine-d4-receptor-gene","display_name":"dopamine D4 receptor gene","score":0.9729999899864197},{"id":"https://openalex.org/keywords/heritability","display_name":"heritability","score":0.9049999713897705},{"id":"https://openalex.org/keywords/mediating-and-moderating-effects","display_name":"mediating and moderating effects","score":0.5899999737739563},{"id":"https://openalex.org/keywords/twin-studies","display_name":"twin studies","score":0.4959999918937683},{"id":"https://openalex.org/keywords/psychometric-properties","display_name":"psychometric properties","score":0.6299999952316284},{"id":"https://openalex.org/keywords/genetic-association","display_name":"genetic association","score":0.3799999952316284}],"concepts":[{"id":"https://openalex.org/C187869287","wikidata":"https://www.wikidata.org/wiki/Q2032061","display_name":"Endophenotype","level":3,"score":0.9908457398414612},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.6832500696182251},{"id":"https://openalex.org/C69991583","wikidata":"https://www.wikidata.org/wiki/Q1423575","display_name":"Candidate gene","level":3,"score":0.6187435388565063},{"id":"https://openalex.org/C2780783007","wikidata":"https://www.wikidata.org/wiki/Q181923","display_name":"Attention deficit hyperactivity disorder","level":2,"score":0.5547453761100769},{"id":"https://openalex.org/C188997412","wikidata":"https://www.wikidata.org/wiki/Q1640386","display_name":"Proband","level":4,"score":0.4678417444229126},{"id":"https://openalex.org/C2776174506","wikidata":"https://www.wikidata.org/wiki/Q131755","display_name":"Bipolar disorder","level":3,"score":0.46758055686950684},{"id":"https://openalex.org/C2780051608","wikidata":"https://www.wikidata.org/wiki/Q42844","display_name":"Major depressive disorder","level":3,"score":0.4605279564857483},{"id":"https://openalex.org/C161890455","wikidata":"https://www.wikidata.org/wiki/Q1503548","display_name":"Heritability","level":2,"score":0.4405940771102905},{"id":"https://openalex.org/C2908647359","wikidata":"https://www.wikidata.org/wiki/Q2625603","display_name":"Population","level":2,"score":0.43460094928741455},{"id":"https://openalex.org/C70410870","wikidata":"https://www.wikidata.org/wiki/Q199906","display_name":"Clinical psychology","level":1,"score":0.4229661226272583},{"id":"https://openalex.org/C118552586","wikidata":"https://www.wikidata.org/wiki/Q7867","display_name":"Psychiatry","level":1,"score":0.364427387714386},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.24679100513458252},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.19523122906684875},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.14123201370239258},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.11731648445129395},{"id":"https://openalex.org/C169900460","wikidata":"https://www.wikidata.org/wiki/Q2200417","display_name":"Cognition","level":2,"score":0.10888803005218506},{"id":"https://openalex.org/C2780733359","wikidata":"https://www.wikidata.org/wiki/Q331769","display_name":"Mood","level":2,"score":0.09996029734611511},{"id":"https://openalex.org/C501734568","wikidata":"https://www.wikidata.org/wiki/Q42918","display_name":"Mutation","level":3,"score":0.06973251700401306},{"id":"https://openalex.org/C99454951","wikidata":"https://www.wikidata.org/wiki/Q932068","display_name":"Environmental health","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000293","descriptor_name":"Adolescent","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001289","descriptor_name":"Attention Deficit Disorder with Hyperactivity","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D001289","descriptor_name":"Attention Deficit Disorder with Hyperactivity","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":true},{"descriptor_ui":"D002648","descriptor_name":"Child","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003072","descriptor_name":"Cognition Disorders","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005192","descriptor_name":"Family Health","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005787","descriptor_name":"Gene Frequency","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009483","descriptor_name":"Neuropsychological Tests","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D010641","descriptor_name":"Phenotype","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D011569","descriptor_name":"Psychiatric Status Rating Scales","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011594","descriptor_name":"Psychometrics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011930","descriptor_name":"Reaction Time","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015233","descriptor_name":"Models, Statistical","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D018433","descriptor_name":"Twin Studies as Topic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020022","descriptor_name":"Genetic Predisposition to Disease","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1016/j.biopsych.2005.03.002","doi":"https://doi.org/10.1016/j.biopsych.2005.03.002","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.biopsych.2005.03.002","pdf_url":null,"source":{"id":"https://openalex.org/S205482884","display_name":"Biological Psychiatry","issn_l":"0006-3223","issn":["0006-3223","1873-2402"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","doyens","erih-plus","jufo-3","ki-jl-2","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biological Psychiatry","raw_type":"journal-article"},{"id":"pmid:15950007","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/15950007","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biological psychiatry","raw_type":"Comparative Study"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.9391000270843506,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G3481610762","display_name":"MOLECULAR GENETICS OF CHILDHOOD DISRUPTIVE DISORDERS","funder_award_id":"K01MH001818","funder_id":"https://openalex.org/F4320337346","funder_display_name":"National Institute of Mental Health"}],"funders":[{"id":"https://openalex.org/F4320337346","display_name":"National Institute of Mental Health","ror":"https://ror.org/04xeg9z08"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":51,"referenced_works":["https://openalex.org/W185953084","https://openalex.org/W190868975","https://openalex.org/W563027580","https://openalex.org/W628516013","https://openalex.org/W1543868019","https://openalex.org/W1561568624","https://openalex.org/W1830481607","https://openalex.org/W1971440513","https://openalex.org/W1997657942","https://openalex.org/W2015251402","https://openalex.org/W2017588448","https://openalex.org/W2023062175","https://openalex.org/W2026213074","https://openalex.org/W2026618249","https://openalex.org/W2026927992","https://openalex.org/W2031999522","https://openalex.org/W2056795330","https://openalex.org/W2058665386","https://openalex.org/W2068942144","https://openalex.org/W2077326149","https://openalex.org/W2077439273","https://openalex.org/W2078625752","https://openalex.org/W2082612867","https://openalex.org/W2083644728","https://openalex.org/W2088372298","https://openalex.org/W2095251402","https://openalex.org/W2096943304","https://openalex.org/W2113918287","https://openalex.org/W2123466824","https://openalex.org/W2126701473","https://openalex.org/W2139468070","https://openalex.org/W2140892327","https://openalex.org/W2141088880","https://openalex.org/W2142256026","https://openalex.org/W2146738944","https://openalex.org/W2146794587","https://openalex.org/W2147549462","https://openalex.org/W2152322012","https://openalex.org/W2156184866","https://openalex.org/W2159401492","https://openalex.org/W2164501949","https://openalex.org/W2319794630","https://openalex.org/W2323058690","https://openalex.org/W2461917396","https://openalex.org/W2478346978","https://openalex.org/W2494603759","https://openalex.org/W2810887452","https://openalex.org/W2902146200","https://openalex.org/W4211142904","https://openalex.org/W4233110100","https://openalex.org/W4285719527"],"related_works":["https://openalex.org/W2131171966","https://openalex.org/W2060513465","https://openalex.org/W2146738944","https://openalex.org/W2070753639","https://openalex.org/W2002409209","https://openalex.org/W2180751342","https://openalex.org/W7100373574","https://openalex.org/W1991330295","https://openalex.org/W2153067051","https://openalex.org/W2325685050"],"abstract_inverted_index":null,"counts_by_year":[{"year":2018,"cited_by_count":1},{"year":2017,"cited_by_count":4},{"year":2016,"cited_by_count":3},{"year":2015,"cited_by_count":8},{"year":2014,"cited_by_count":13},{"year":2013,"cited_by_count":7},{"year":2012,"cited_by_count":7}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}