{"id":"https://openalex.org/W1966192244","doi":"https://doi.org/10.1016/s0969-8051(97)00027-9","title":"Preparation and Use of NHS-MAG3 for Technetium-99m Labeling of DNA","display_name":"Preparation and Use of NHS-MAG3 for Technetium-99m Labeling of DNA","publication_year":1997,"publication_date":"1997-07-01","ids":{"openalex":"https://openalex.org/W1966192244","doi":"https://doi.org/10.1016/s0969-8051(97)00027-9","mag":"1966192244","pmid":"https://pubmed.ncbi.nlm.nih.gov/9290078"},"language":"en","primary_location":{"id":"doi:10.1016/s0969-8051(97)00027-9","doi":"https://doi.org/10.1016/s0969-8051(97)00027-9","is_oa":false,"landing_page_url":"https://doi.org/10.1016/s0969-8051(97)00027-9","pdf_url":null,"source":{"id":"https://openalex.org/S24354371","display_name":"Nuclear Medicine and Biology","issn_l":"0969-8051","issn":["0969-8051","1872-9614"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nuclear Medicine and Biology","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5109104929","display_name":"Paul Winnard","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I166722992","display_name":"University of Massachusetts Chan Medical School","ror":"https://ror.org/0464eyp60","country_code":"US","type":"education","lineage":["https://openalex.org/I166722992"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"P. Winnard","raw_affiliation_strings":["DEPARTMENT OF NUCLEAR MEDICINE, UNIVERSITY OF MASSACHUSETTS MEDICAL CENTER, WORCESTER, MA. 01655 USA","Department of Nuclear Medicine, University of Massachusetts Medical Center, Worcester 01655, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"DEPARTMENT OF NUCLEAR MEDICINE, UNIVERSITY OF MASSACHUSETTS MEDICAL CENTER, WORCESTER, MA. 01655 USA","institution_ids":["https://openalex.org/I166722992"]},{"raw_affiliation_string":"Department of Nuclear Medicine, University of Massachusetts Medical Center, Worcester 01655, USA","institution_ids":["https://openalex.org/I166722992"]}]},{"author_position":"middle","author":{"id":null,"display_name":"F. Chang","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I166722992","display_name":"University of Massachusetts Chan Medical School","ror":"https://ror.org/0464eyp60","country_code":"US","type":"education","lineage":["https://openalex.org/I166722992"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"F. Chang","raw_affiliation_strings":["DEPARTMENT OF NUCLEAR MEDICINE, UNIVERSITY OF MASSACHUSETTS MEDICAL CENTER, WORCESTER, MA. 01655 USA","Department of Nuclear Medicine, University of Massachusetts Medical Center, Worcester, MA 01655, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"DEPARTMENT OF NUCLEAR MEDICINE, UNIVERSITY OF MASSACHUSETTS MEDICAL CENTER, WORCESTER, MA. 01655 USA","institution_ids":["https://openalex.org/I166722992"]},{"raw_affiliation_string":"Department of Nuclear Medicine, University of Massachusetts Medical Center, Worcester, MA 01655, USA","institution_ids":["https://openalex.org/I166722992"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5091137372","display_name":"Mary Rusckowski","orcid":"https://orcid.org/0000-0003-2246-6883","observed_orcids":["https://orcid.org/0000-0003-2246-6883"]},"institutions":[{"id":"https://openalex.org/I166722992","display_name":"University of Massachusetts Chan Medical School","ror":"https://ror.org/0464eyp60","country_code":"US","type":"education","lineage":["https://openalex.org/I166722992"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"M. Rusckowski","raw_affiliation_strings":["DEPARTMENT OF NUCLEAR MEDICINE, UNIVERSITY OF MASSACHUSETTS MEDICAL CENTER, WORCESTER, MA. 01655 USA","Department of Nuclear Medicine, University of Massachusetts Medical Center, Worcester, MA 01655, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"DEPARTMENT OF NUCLEAR MEDICINE, UNIVERSITY OF MASSACHUSETTS MEDICAL CENTER, WORCESTER, MA. 01655 USA","institution_ids":["https://openalex.org/I166722992"]},{"raw_affiliation_string":"Department of Nuclear Medicine, University of Massachusetts Medical Center, Worcester, MA 01655, USA","institution_ids":["https://openalex.org/I166722992"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5035319241","display_name":"George Mardirossian","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I166722992","display_name":"University of Massachusetts Chan Medical School","ror":"https://ror.org/0464eyp60","country_code":"US","type":"education","lineage":["https://openalex.org/I166722992"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"G. Mardirossian","raw_affiliation_strings":["DEPARTMENT OF NUCLEAR MEDICINE, UNIVERSITY OF MASSACHUSETTS MEDICAL CENTER, WORCESTER, MA. 01655 USA","Department of Nuclear Medicine, University of Massachusetts Medical Center, Worcester, MA 01655, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"DEPARTMENT OF NUCLEAR MEDICINE, UNIVERSITY OF MASSACHUSETTS MEDICAL CENTER, WORCESTER, MA. 01655 USA","institution_ids":["https://openalex.org/I166722992"]},{"raw_affiliation_string":"Department of Nuclear Medicine, University of Massachusetts Medical Center, Worcester, MA 01655, USA","institution_ids":["https://openalex.org/I166722992"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5113992277","display_name":"Donald J. Hnatowich","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I166722992","display_name":"University of Massachusetts Chan Medical School","ror":"https://ror.org/0464eyp60","country_code":"US","type":"education","lineage":["https://openalex.org/I166722992"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"D.J. Hnatowich","raw_affiliation_strings":["DEPARTMENT OF NUCLEAR MEDICINE, UNIVERSITY OF MASSACHUSETTS MEDICAL CENTER, WORCESTER, MA. 01655 USA","Department of Nuclear Medicine, University of Massachusetts Medical Center, Worcester, MA 01655, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"DEPARTMENT OF NUCLEAR MEDICINE, UNIVERSITY OF MASSACHUSETTS MEDICAL CENTER, WORCESTER, MA. 01655 USA","institution_ids":["https://openalex.org/I166722992"]},{"raw_affiliation_string":"Department of Nuclear Medicine, University of Massachusetts Medical Center, Worcester, MA 01655, USA","institution_ids":["https://openalex.org/I166722992"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5113992277"],"corresponding_institution_ids":["https://openalex.org/I166722992"],"apc_list":{"value":3740,"currency":"USD","value_usd":3740},"apc_paid":null,"fwci":4.7326,"has_fulltext":false,"cited_by_count":93,"citation_normalized_percentile":{"value":0.94594898,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":98},"biblio":{"volume":"24","issue":"5","first_page":"425","last_page":"432"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11395","display_name":"Radiopharmaceutical Chemistry and Applications","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11395","display_name":"Radiopharmaceutical Chemistry and Applications","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T13561","display_name":"Chemical Reactions and Isotopes","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/3003","display_name":"Pharmaceutical Science"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11279","display_name":"Lanthanide and Transition Metal Complexes","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2505","display_name":"Materials Chemistry"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/technetium-99m","display_name":"technetium-99m","score":0.972000002861023},{"id":"https://openalex.org/keywords/n-hydroxysuccinimide-ester","display_name":"N-hydroxysuccinimide ester","score":0.8999999761581421},{"id":"https://openalex.org/keywords/transchelation","display_name":"transchelation","score":0.8579999804496765},{"id":"https://openalex.org/keywords/plasma-protein-binding","display_name":"plasma protein binding","score":0.6330000162124634},{"id":"https://openalex.org/keywords/bifunctional-chelators","display_name":"bifunctional chelators","score":0.718999981880188},{"id":"https://openalex.org/keywords/radiolabeled-dna","display_name":"radiolabeled DNA","score":0.5230000019073486}],"concepts":[{"id":"https://openalex.org/C177322064","wikidata":"https://www.wikidata.org/wiki/Q750955","display_name":"Radiochemistry","level":1,"score":0.5539572834968567},{"id":"https://openalex.org/C4375535","wikidata":"https://www.wikidata.org/wiki/Q2373354","display_name":"Technetium-99m","level":3,"score":0.5533581972122192},{"id":"https://openalex.org/C522557706","wikidata":"https://www.wikidata.org/wiki/Q1054","display_name":"Technetium","level":2,"score":0.5512795448303223},{"id":"https://openalex.org/C552990157","wikidata":"https://www.wikidata.org/wiki/Q7430","display_name":"DNA","level":2,"score":0.4345777630805969},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.4049743413925171},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.36306822299957275},{"id":"https://openalex.org/C2989005","wikidata":"https://www.wikidata.org/wiki/Q214963","display_name":"Nuclear medicine","level":1,"score":0.3366413116455078},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.1279323697090149},{"id":"https://openalex.org/C2779902710","wikidata":"https://www.wikidata.org/wiki/Q1130465","display_name":"Scintigraphy","level":2,"score":0.1131262481212616}],"mesh":[{"descriptor_ui":"D002614","descriptor_name":"Chelating Agents","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D002614","descriptor_name":"Chelating Agents","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D002614","descriptor_name":"Chelating Agents","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D002851","descriptor_name":"Chromatography, High Pressure Liquid","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002851","descriptor_name":"Chromatography, High Pressure Liquid","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002851","descriptor_name":"Chromatography, High Pressure Liquid","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004247","descriptor_name":"DNA","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D004247","descriptor_name":"DNA","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D004247","descriptor_name":"DNA","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D005998","descriptor_name":"Glycine","qualifier_ui":"Q000031","qualifier_name":"analogs & derivatives","is_major_topic":false},{"descriptor_ui":"D005998","descriptor_name":"Glycine","qualifier_ui":"Q000031","qualifier_name":"analogs & derivatives","is_major_topic":false},{"descriptor_ui":"D005998","descriptor_name":"Glycine","qualifier_ui":"Q000031","qualifier_name":"analogs & derivatives","is_major_topic":false},{"descriptor_ui":"D005998","descriptor_name":"Glycine","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D005998","descriptor_name":"Glycine","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D005998","descriptor_name":"Glycine","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D007553","descriptor_name":"Isotope Labeling","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D007553","descriptor_name":"Isotope Labeling","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D007553","descriptor_name":"Isotope Labeling","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D009682","descriptor_name":"Magnetic Resonance Spectroscopy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009682","descriptor_name":"Magnetic Resonance Spectroscopy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009682","descriptor_name":"Magnetic Resonance Spectroscopy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013388","descriptor_name":"Succinimides","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D013388","descriptor_name":"Succinimides","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D013388","descriptor_name":"Succinimides","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D013667","descriptor_name":"Technetium","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D013667","descriptor_name":"Technetium","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D013667","descriptor_name":"Technetium","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":3,"locations":[{"id":"doi:10.1016/s0969-8051(97)00027-9","doi":"https://doi.org/10.1016/s0969-8051(97)00027-9","is_oa":false,"landing_page_url":"https://doi.org/10.1016/s0969-8051(97)00027-9","pdf_url":null,"source":{"id":"https://openalex.org/S24354371","display_name":"Nuclear Medicine and Biology","issn_l":"0969-8051","issn":["0969-8051","1872-9614"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nuclear Medicine and Biology","raw_type":"journal-article"},{"id":"doi:10.1016/s0969-8051(97)80010-8","doi":"https://doi.org/10.1016/s0969-8051(97)80010-8","is_oa":false,"landing_page_url":"https://doi.org/10.1016/s0969-8051(97)80010-8","pdf_url":null,"source":{"id":"https://openalex.org/S24354371","display_name":"Nuclear Medicine and Biology","issn_l":"0969-8051","issn":["0969-8051","1872-9614"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nuclear Medicine and Biology","raw_type":"journal-article"},{"id":"pmid:9290078","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/9290078","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nuclear medicine and biology","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[],"sustainable_development_goals_aurora":[{"score":0.8700000047683716,"id":"https://metadata.un.org/sdg/6","display_name":"Clean water and sanitation"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G4283155094","display_name":"RE188 LABELED MOABS--A COMPARISION OF LABELING METHODS","funder_award_id":"5r01ca059785-03","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G4863662117","display_name":null,"funder_award_id":"CA59785","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"}],"funders":[{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337351","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":22,"referenced_works":["https://openalex.org/W79676359","https://openalex.org/W618995522","https://openalex.org/W1504334508","https://openalex.org/W1903515830","https://openalex.org/W1965569089","https://openalex.org/W1969839030","https://openalex.org/W1988220558","https://openalex.org/W1989506047","https://openalex.org/W2004340078","https://openalex.org/W2004532756","https://openalex.org/W2056038327","https://openalex.org/W2065239575","https://openalex.org/W2079919567","https://openalex.org/W2082569850","https://openalex.org/W2103646729","https://openalex.org/W2112933027","https://openalex.org/W2115754415","https://openalex.org/W2148054111","https://openalex.org/W2413426199","https://openalex.org/W6675725564","https://openalex.org/W6677043833","https://openalex.org/W6681999404"],"related_works":["https://openalex.org/W1992269625","https://openalex.org/W2010351597","https://openalex.org/W1999411306","https://openalex.org/W2393395577","https://openalex.org/W1511041898","https://openalex.org/W2160813328","https://openalex.org/W2056496694","https://openalex.org/W2025024860","https://openalex.org/W1970064489","https://openalex.org/W1974301585"],"abstract_inverted_index":null,"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2023,"cited_by_count":1},{"year":2021,"cited_by_count":1},{"year":2018,"cited_by_count":2},{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":2},{"year":2015,"cited_by_count":5},{"year":2013,"cited_by_count":1},{"year":2012,"cited_by_count":1}],"updated_date":"2026-10-17T09:40:24.721904","created_date":"2016-06-24T00:00:00"}