{"id":"https://openalex.org/W1966154792","doi":"https://doi.org/10.1203/01.pdr.0000203145.48585.2c","title":"Family-Based Association Tests Suggest Linkage Between Surfactant Protein B (SP-B) (and Flanking Region) and Respiratory Distress Syndrome (RDS): SP-B Haplotypes and Alleles From SP-B\u2013Linked Loci Are Risk Factors for RDS","display_name":"Family-Based Association Tests Suggest Linkage Between Surfactant Protein B (SP-B) (and Flanking Region) and Respiratory Distress Syndrome (RDS): SP-B Haplotypes and Alleles From SP-B\u2013Linked Loci Are Risk Factors for RDS","publication_year":2006,"publication_date":"2006-03-20","ids":{"openalex":"https://openalex.org/W1966154792","doi":"https://doi.org/10.1203/01.pdr.0000203145.48585.2c","mag":"1966154792","pmid":"https://pubmed.ncbi.nlm.nih.gov/16549540"},"language":"en","primary_location":{"id":"doi:10.1203/01.pdr.0000203145.48585.2c","doi":"https://doi.org/10.1203/01.pdr.0000203145.48585.2c","is_oa":false,"landing_page_url":"https://doi.org/10.1203/01.pdr.0000203145.48585.2c","pdf_url":null,"source":{"id":"https://openalex.org/S167664057","display_name":"Pediatric Research","issn_l":"0031-3998","issn":["0031-3998","1530-0447"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319965","host_organization_name":"Springer Nature","host_organization_lineage":["https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Pediatric Research","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5045307901","display_name":"Joanna Floros","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I130769515","display_name":"Pennsylvania State University","ror":"https://ror.org/04p491231","country_code":"US","type":"education","lineage":["https://openalex.org/I130769515"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Joanna Floros","raw_affiliation_strings":["Department of Cellular and Molecular Physiology, The Pennsylvania State University College of Medicine, Hershey, PA 17033, USA. jfloros@psu.edu","Department of Gynecology, College Station, The Pennsylvania State University College of Medicine, Hershey","Department of Pediatrics, Obstetrics College Station, The Pennsylvania State University College of Medicine, Hershey","Departments of Cellular and Molecular Physiology, The Pennsylvania State University College of Medicine, Hershey"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cellular and Molecular Physiology, The Pennsylvania State University College of Medicine, Hershey, PA 17033, USA. jfloros@psu.edu","institution_ids":["https://openalex.org/I130769515"]},{"raw_affiliation_string":"Department of Gynecology, College Station, The Pennsylvania State University College of Medicine, Hershey","institution_ids":["https://openalex.org/I130769515"]},{"raw_affiliation_string":"Department of Pediatrics, Obstetrics College Station, The Pennsylvania State University College of Medicine, Hershey","institution_ids":["https://openalex.org/I130769515"]},{"raw_affiliation_string":"Departments of Cellular and Molecular Physiology, The Pennsylvania State University College of Medicine, Hershey","institution_ids":["https://openalex.org/I130769515"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5069821127","display_name":"Neal J. Thomas","orcid":"https://orcid.org/0000-0002-7991-7510","observed_orcids":["https://orcid.org/0000-0002-7991-7510"]},"institutions":[{"id":"https://openalex.org/I130769515","display_name":"Pennsylvania State University","ror":"https://ror.org/04p491231","country_code":"US","type":"education","lineage":["https://openalex.org/I130769515"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Neal J Thomas","raw_affiliation_strings":["Department of Health Evaluation Sciences, The Pennsylvania State University College of Medicine, Hershey, 17033, PA","Department of Pediatrics, Obstetrics College Station, The Pennsylvania State University College of Medicine, Hershey, 17033, PA","Department of Health Evaluation Sciences, The Pennsylvania State University College of Medicine, Hershey","Department of Pediatrics, Obstetrics College Station, The Pennsylvania State University College of Medicine, Hershey"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Health Evaluation Sciences, The Pennsylvania State University College of Medicine, Hershey, 17033, PA","institution_ids":["https://openalex.org/I130769515"]},{"raw_affiliation_string":"Department of Pediatrics, Obstetrics College Station, The Pennsylvania State University College of Medicine, Hershey, 17033, PA","institution_ids":["https://openalex.org/I130769515"]},{"raw_affiliation_string":"Department of Health Evaluation Sciences, The Pennsylvania State University College of Medicine, Hershey","institution_ids":["https://openalex.org/I130769515"]},{"raw_affiliation_string":"Department of Pediatrics, Obstetrics College Station, The Pennsylvania State University College of Medicine, Hershey","institution_ids":["https://openalex.org/I130769515"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5102863769","display_name":"Wenlei Liu","orcid":"https://orcid.org/0000-0002-2783-3681","observed_orcids":["https://orcid.org/0000-0002-2783-3681"]},"institutions":[{"id":"https://openalex.org/I130769515","display_name":"Pennsylvania State University","ror":"https://ror.org/04p491231","country_code":"US","type":"education","lineage":["https://openalex.org/I130769515"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Wenlei Liu","raw_affiliation_strings":["Department of Health Evaluation Sciences, The Pennsylvania State University College of Medicine, Hershey, 17033, PA","Department of Health Evaluation Sciences, The Pennsylvania State University College of Medicine, Hershey"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Health Evaluation Sciences, The Pennsylvania State University College of Medicine, Hershey, 17033, PA","institution_ids":["https://openalex.org/I130769515"]},{"raw_affiliation_string":"Department of Health Evaluation Sciences, The Pennsylvania State University College of Medicine, Hershey","institution_ids":["https://openalex.org/I130769515"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5009864440","display_name":"Costas Papagaroufalis","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210120313","display_name":"Children's Hospital Agia Sophia","ror":"https://ror.org/0315ea826","country_code":"GR","type":"healthcare","lineage":["https://openalex.org/I4210120313"]}],"countries":["GR"],"is_corresponding":false,"raw_author_name":"Costas Papagaroufalis","raw_affiliation_strings":["Aghia Sophia Children's Hospital, Athens, 1527, Greece","Aghia Sophia Children's Hospital, Athens, Greece"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Aghia Sophia Children's Hospital, Athens, 1527, Greece","institution_ids":["https://openalex.org/I4210120313"]},{"raw_affiliation_string":"Aghia Sophia Children's Hospital, Athens, Greece","institution_ids":["https://openalex.org/I4210120313"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5080257160","display_name":"Marietta Xanthou","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210120313","display_name":"Children's Hospital Agia Sophia","ror":"https://ror.org/0315ea826","country_code":"GR","type":"healthcare","lineage":["https://openalex.org/I4210120313"]}],"countries":["GR"],"is_corresponding":false,"raw_author_name":"Marietta Xanthou","raw_affiliation_strings":["Aghia Sophia Children's Hospital, Athens, 1527, Greece","Aghia Sophia Children's Hospital, Athens, Greece"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Aghia Sophia Children's Hospital, Athens, 1527, Greece","institution_ids":["https://openalex.org/I4210120313"]},{"raw_affiliation_string":"Aghia Sophia Children's Hospital, Athens, Greece","institution_ids":["https://openalex.org/I4210120313"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110625174","display_name":"Sunita Pereira","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1290900354","display_name":"Tufts Medical Center","ror":"https://ror.org/002hsbm82","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1290900354"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Sunita Pereira","raw_affiliation_strings":["Division of Newborn Medicine, Tufts New England Medical Center, Boston, 02111, MA","Division of Newborn Medicine, Tufts New England Medical Center, Boston"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Newborn Medicine, Tufts New England Medical Center, Boston, 02111, MA","institution_ids":["https://openalex.org/I1290900354"]},{"raw_affiliation_string":"Division of Newborn Medicine, Tufts New England Medical Center, Boston","institution_ids":["https://openalex.org/I1290900354"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5013409053","display_name":"Ruzong Fan","orcid":"https://orcid.org/0000-0002-7603-2135","observed_orcids":["https://orcid.org/0000-0002-7603-2135"]},"institutions":[{"id":"https://openalex.org/I91045830","display_name":"Texas A&M University","ror":"https://ror.org/01f5ytq51","country_code":"US","type":"education","lineage":["https://openalex.org/I91045830"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Ruzong Fan","raw_affiliation_strings":["Department of Statistics, TX A&M University, College Station, 77843, TX","Department of Statistics, TX A&M University, College Station"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Statistics, TX A&M University, College Station, 77843, TX","institution_ids":["https://openalex.org/I91045830"]},{"raw_affiliation_string":"Department of Statistics, TX A&M University, College Station","institution_ids":["https://openalex.org/I91045830"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101950548","display_name":"Xiaoxuan Guo","orcid":"https://orcid.org/0000-0003-2018-3468","observed_orcids":["https://orcid.org/0000-0003-2018-3468"]},"institutions":[{"id":"https://openalex.org/I130769515","display_name":"Pennsylvania State University","ror":"https://ror.org/04p491231","country_code":"US","type":"education","lineage":["https://openalex.org/I130769515"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Xiaoxuan Guo","raw_affiliation_strings":["Departments of Cellular and Molecular Physiology, The Pennsylvania State University College of Medicine, Hershey, 17033, PA","Departments of Cellular and Molecular Physiology, The Pennsylvania State University College of Medicine, Hershey"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departments of Cellular and Molecular Physiology, The Pennsylvania State University College of Medicine, Hershey, 17033, PA","institution_ids":["https://openalex.org/I130769515"]},{"raw_affiliation_string":"Departments of Cellular and Molecular Physiology, The Pennsylvania State University College of Medicine, Hershey","institution_ids":["https://openalex.org/I130769515"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5066903326","display_name":"Susan L. DiAngelo","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I130769515","display_name":"Pennsylvania State University","ror":"https://ror.org/04p491231","country_code":"US","type":"education","lineage":["https://openalex.org/I130769515"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Susan Diangelo","raw_affiliation_strings":["Departments of Cellular and Molecular Physiology, The Pennsylvania State University College of Medicine, Hershey, 17033, PA","Departments of Cellular and Molecular Physiology, The Pennsylvania State University College of Medicine, Hershey"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departments of Cellular and Molecular Physiology, The Pennsylvania State University College of Medicine, Hershey, 17033, PA","institution_ids":["https://openalex.org/I130769515"]},{"raw_affiliation_string":"Departments of Cellular and Molecular Physiology, The Pennsylvania State University College of Medicine, Hershey","institution_ids":["https://openalex.org/I130769515"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5018036182","display_name":"Jelena Pavlovi\u0107","orcid":"https://orcid.org/0009-0002-4249-9551","observed_orcids":["https://orcid.org/0009-0002-4249-9551"]},"institutions":[{"id":"https://openalex.org/I130769515","display_name":"Pennsylvania State University","ror":"https://ror.org/04p491231","country_code":"US","type":"education","lineage":["https://openalex.org/I130769515"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jelena Pavlovic","raw_affiliation_strings":["Departments of Cellular and Molecular Physiology, The Pennsylvania State University College of Medicine, Hershey, 17033, PA","Departments of Cellular and Molecular Physiology, The Pennsylvania State University College of Medicine, Hershey"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departments of Cellular and Molecular Physiology, The Pennsylvania State University College of Medicine, Hershey, 17033, PA","institution_ids":["https://openalex.org/I130769515"]},{"raw_affiliation_string":"Departments of Cellular and Molecular Physiology, The Pennsylvania State University College of Medicine, Hershey","institution_ids":["https://openalex.org/I130769515"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5045307901"],"corresponding_institution_ids":["https://openalex.org/I130769515"],"apc_list":{"value":4390,"currency":"USD","value_usd":4390},"apc_paid":null,"fwci":2.0643,"has_fulltext":true,"cited_by_count":20,"citation_normalized_percentile":{"value":0.86457438,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":96},"biblio":{"volume":"59","issue":"4 Part 1","first_page":"616","last_page":"621"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10549","display_name":"Neonatal Respiratory Health Research","score":0.9945999979972839,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10549","display_name":"Neonatal Respiratory Health Research","score":0.9945999979972839,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10261","display_name":"Genetic Associations and Epidemiology","score":0.003100000089034438,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11456","display_name":"Neuroscience of respiration and sleep","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/2807","display_name":"Endocrine and Autonomic Systems"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/surfactant-protein-b","display_name":"surfactant protein B","score":0.9950000047683716},{"id":"https://openalex.org/keywords/respiratory-distress-syndrome","display_name":"respiratory distress syndrome","score":0.9950000047683716},{"id":"https://openalex.org/keywords/preterm-infants","display_name":"preterm infants","score":0.8019999861717224},{"id":"https://openalex.org/keywords/genetic-linkage","display_name":"genetic linkage","score":0.9150000214576721},{"id":"https://openalex.org/keywords/haplotypes","display_name":"haplotypes","score":0.7480000257492065},{"id":"https://openalex.org/keywords/single-nucleotide-polymorphisms","display_name":"single nucleotide polymorphisms","score":0.9259999990463257},{"id":"https://openalex.org/keywords/microsatellite-markers","display_name":"microsatellite markers","score":0.800000011920929},{"id":"https://openalex.org/keywords/family-based-association-test","display_name":"family-based association test","score":0.7269999980926514},{"id":"https://openalex.org/keywords/genetic-susceptibility","display_name":"genetic susceptibility","score":0.8309999704360962}],"concepts":[{"id":"https://openalex.org/C197754878","wikidata":"https://www.wikidata.org/wiki/Q80711","display_name":"Haplotype","level":4,"score":0.7555462718009949},{"id":"https://openalex.org/C180754005","wikidata":"https://www.wikidata.org/wiki/Q80726","display_name":"Allele","level":3,"score":0.7415751218795776},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.6851810216903687},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.5435038805007935},{"id":"https://openalex.org/C141983124","wikidata":"https://www.wikidata.org/wiki/Q188008","display_name":"Respiratory distress","level":2,"score":0.5397222638130188},{"id":"https://openalex.org/C31266012","wikidata":"https://www.wikidata.org/wiki/Q6554340","display_name":"Linkage (software)","level":3,"score":0.5154784321784973},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.3634198307991028},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.2585919499397278},{"id":"https://openalex.org/C42219234","wikidata":"https://www.wikidata.org/wiki/Q131130","display_name":"Anesthesia","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002648","descriptor_name":"Child","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006239","descriptor_name":"Haplotypes","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007231","descriptor_name":"Infant, Newborn","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007234","descriptor_name":"Infant, Premature","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008040","descriptor_name":"Genetic Linkage","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012127","descriptor_name":"Respiratory Distress Syndrome, Newborn","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D012307","descriptor_name":"Risk Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018895","descriptor_name":"Microsatellite Repeats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D037701","descriptor_name":"Pulmonary Surfactant-Associated Protein B","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D037701","descriptor_name":"Pulmonary Surfactant-Associated Protein B","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1203/01.pdr.0000203145.48585.2c","doi":"https://doi.org/10.1203/01.pdr.0000203145.48585.2c","is_oa":false,"landing_page_url":"https://doi.org/10.1203/01.pdr.0000203145.48585.2c","pdf_url":null,"source":{"id":"https://openalex.org/S167664057","display_name":"Pediatric Research","issn_l":"0031-3998","issn":["0031-3998","1530-0447"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319965","host_organization_name":"Springer Nature","host_organization_lineage":["https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Pediatric Research","raw_type":"journal-article"},{"id":"pmid:16549540","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/16549540","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Pediatric research","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.9940000176429749,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"sustainable_development_goals_aurora":[{"score":0.5600000023841858,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[{"id":"https://openalex.org/G2377467433","display_name":"SURFACTANT PROTEINS AND RESPIRATORY DISTRESS SYNDROME","funder_award_id":"R37HL034788","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"},{"id":"https://openalex.org/G3335924918","display_name":"GCRC RELOCATION AND EXPANSION PROJECT","funder_award_id":"C06RR016499","funder_id":"https://openalex.org/F4320337375","funder_display_name":"National Center for Research Resources"},{"id":"https://openalex.org/G3410803254","display_name":"General Clinical Research Center","funder_award_id":"M01RR010732","funder_id":"https://openalex.org/F4320337375","funder_display_name":"National Center for Research Resources"}],"funders":[{"id":"https://openalex.org/F4320310419","display_name":"Pennsylvania State University","ror":"https://ror.org/04p491231"},{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320333195","display_name":"Penn State College of Medicine","ror":null},{"id":"https://openalex.org/F4320337338","display_name":"National Heart, Lung, and Blood Institute","ror":"https://ror.org/012pb6c26"},{"id":"https://openalex.org/F4320337375","display_name":"National Center for Research Resources","ror":"https://ror.org/04pw6fb54"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":43,"referenced_works":["https://openalex.org/W53510971","https://openalex.org/W83722529","https://openalex.org/W1479707731","https://openalex.org/W1542836032","https://openalex.org/W1547943040","https://openalex.org/W1553527720","https://openalex.org/W1577972870","https://openalex.org/W1590214419","https://openalex.org/W1602732899","https://openalex.org/W1622080092","https://openalex.org/W1966446054","https://openalex.org/W1974977343","https://openalex.org/W1977945634","https://openalex.org/W1990402565","https://openalex.org/W1999824226","https://openalex.org/W2006553231","https://openalex.org/W2016894107","https://openalex.org/W2019094071","https://openalex.org/W2052071194","https://openalex.org/W2054933658","https://openalex.org/W2059618318","https://openalex.org/W2063102503","https://openalex.org/W2068904861","https://openalex.org/W2072038834","https://openalex.org/W2081589751","https://openalex.org/W2098611654","https://openalex.org/W2107871825","https://openalex.org/W2113218577","https://openalex.org/W2113686392","https://openalex.org/W2120884330","https://openalex.org/W2132869897","https://openalex.org/W2138605912","https://openalex.org/W2147034448","https://openalex.org/W2154027290","https://openalex.org/W2156989422","https://openalex.org/W2159477646","https://openalex.org/W2161020347","https://openalex.org/W2164511664","https://openalex.org/W2180006187","https://openalex.org/W2315295323","https://openalex.org/W2339550260","https://openalex.org/W2418651081","https://openalex.org/W4240660705"],"related_works":["https://openalex.org/W2138605912","https://openalex.org/W4281483928","https://openalex.org/W2120884330","https://openalex.org/W2231908034","https://openalex.org/W1587318783","https://openalex.org/W2736674305","https://openalex.org/W2552540370","https://openalex.org/W1999824226","https://openalex.org/W1983502555","https://openalex.org/W2020005960"],"abstract_inverted_index":null,"counts_by_year":[{"year":2024,"cited_by_count":2},{"year":2022,"cited_by_count":2},{"year":2021,"cited_by_count":1},{"year":2012,"cited_by_count":2}],"updated_date":"2026-11-01T11:40:01.658920","created_date":"2016-06-24T00:00:00"}