{"id":"https://openalex.org/W1966071985","doi":"https://doi.org/10.1038/sj.onc.1203674","title":"Hepatitis B virus-X protein upregulates the expression of p21wafl/cipl and prolongs G1\u2192S transition via a p53-independent pathway in human hepatoma cells","display_name":"Hepatitis B virus-X protein upregulates the expression of p21wafl/cipl and prolongs G1\u2192S transition via a p53-independent pathway in human hepatoma cells","publication_year":2000,"publication_date":"2000-07-13","ids":{"openalex":"https://openalex.org/W1966071985","doi":"https://doi.org/10.1038/sj.onc.1203674","mag":"1966071985","pmid":"https://pubmed.ncbi.nlm.nih.gov/10918595"},"language":"en","primary_location":{"id":"doi:10.1038/sj.onc.1203674","doi":"https://doi.org/10.1038/sj.onc.1203674","is_oa":false,"landing_page_url":"https://doi.org/10.1038/sj.onc.1203674","pdf_url":null,"source":{"id":"https://openalex.org/S128439998","display_name":"Oncogene","issn_l":"0950-9232","issn":["0950-9232","1476-5594"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319965","host_organization_name":"Springer Nature","host_organization_lineage":["https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Oncogene","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"http://www.nature.com/articles/1203674","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5109139008","display_name":"Ui Sun Park","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I73616290","display_name":"Korea Research Institute of Bioscience and Biotechnology","ror":"https://ror.org/03ep23f07","country_code":"KR","type":"facility","lineage":["https://openalex.org/I2801339556","https://openalex.org/I4210144908","https://openalex.org/I4387152098","https://openalex.org/I73616290"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Ui Sun Park","raw_affiliation_strings":["Bioscience Research Division, Korea Research Institute of Bioscience and Biotechnology, Yusong, Taejon","Bioscience Research Division, Liver Cell Signal Transduction Research Unit, Korea Research Institute of Bioscience and Biotechnology, Yusong, Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Bioscience Research Division, Korea Research Institute of Bioscience and Biotechnology, Yusong, Taejon","institution_ids":["https://openalex.org/I73616290"]},{"raw_affiliation_string":"Bioscience Research Division, Liver Cell Signal Transduction Research Unit, Korea Research Institute of Bioscience and Biotechnology, Yusong, Korea","institution_ids":["https://openalex.org/I73616290"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5029143634","display_name":"Sook Kyung Park","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I73616290","display_name":"Korea Research Institute of Bioscience and Biotechnology","ror":"https://ror.org/03ep23f07","country_code":"KR","type":"facility","lineage":["https://openalex.org/I2801339556","https://openalex.org/I4210144908","https://openalex.org/I4387152098","https://openalex.org/I73616290"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Sook Kyung Park","raw_affiliation_strings":["Bioscience Research Division, Liver Cell Signal Transduction Research Unit, Korea Research Institute of Bioscience and Biotechnology, P.O. Box 115, Yusong, 305-600, Taejon, Korea","Bioscience Research Division, Liver Cell Signal Transduction Research Unit, Korea Research Institute of Bioscience and Biotechnology, Yusong, Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Bioscience Research Division, Liver Cell Signal Transduction Research Unit, Korea Research Institute of Bioscience and Biotechnology, P.O. Box 115, Yusong, 305-600, Taejon, Korea","institution_ids":["https://openalex.org/I73616290"]},{"raw_affiliation_string":"Bioscience Research Division, Liver Cell Signal Transduction Research Unit, Korea Research Institute of Bioscience and Biotechnology, Yusong, Korea","institution_ids":["https://openalex.org/I73616290"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111671980","display_name":"Yoon Ik Lee","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I73616290","display_name":"Korea Research Institute of Bioscience and Biotechnology","ror":"https://ror.org/03ep23f07","country_code":"KR","type":"facility","lineage":["https://openalex.org/I2801339556","https://openalex.org/I4210144908","https://openalex.org/I4387152098","https://openalex.org/I73616290"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Yoon Ik Lee","raw_affiliation_strings":["Bioscience Research Division, Liver Cell Signal Transduction Research Unit, Korea Research Institute of Bioscience and Biotechnology, P.O. Box 115, Yusong, 305-600, Taejon, Korea","Bioscience Research Division, Liver Cell Signal Transduction Research Unit, Korea Research Institute of Bioscience and Biotechnology, Yusong, Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Bioscience Research Division, Liver Cell Signal Transduction Research Unit, Korea Research Institute of Bioscience and Biotechnology, P.O. Box 115, Yusong, 305-600, Taejon, Korea","institution_ids":["https://openalex.org/I73616290"]},{"raw_affiliation_string":"Bioscience Research Division, Liver Cell Signal Transduction Research Unit, Korea Research Institute of Bioscience and Biotechnology, Yusong, Korea","institution_ids":["https://openalex.org/I73616290"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113521637","display_name":"Jong Gu Park","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I52010207","display_name":"Keimyung University","ror":"https://ror.org/00tjv0s33","country_code":"KR","type":"education","lineage":["https://openalex.org/I52010207"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Jong Gu Park","raw_affiliation_strings":["Institute of Medical Science, Keymyung University, Tae-Ku, 700-301, Korea","Institute of Medical Science, Keymyung University, Tae-Ku, Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Medical Science, Keymyung University, Tae-Ku, 700-301, Korea","institution_ids":["https://openalex.org/I52010207"]},{"raw_affiliation_string":"Institute of Medical Science, Keymyung University, Tae-Ku, Korea","institution_ids":["https://openalex.org/I52010207"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5111867650","display_name":"Young Ik Lee","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I73616290","display_name":"Korea Research Institute of Bioscience and Biotechnology","ror":"https://ror.org/03ep23f07","country_code":"KR","type":"facility","lineage":["https://openalex.org/I2801339556","https://openalex.org/I4210144908","https://openalex.org/I4387152098","https://openalex.org/I73616290"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Young Ik Lee","raw_affiliation_strings":["Bioscience Research Division, Liver Cell Signal Transduction Research Unit, Korea Research Institute of Bioscience and Biotechnology, P.O. Box 115, Yusong, 305-600, Taejon, Korea","Bioscience Research Division, Liver Cell Signal Transduction Research Unit, Korea Research Institute of Bioscience and Biotechnology, Yusong, Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Bioscience Research Division, Liver Cell Signal Transduction Research Unit, Korea Research Institute of Bioscience and Biotechnology, P.O. Box 115, Yusong, 305-600, Taejon, Korea","institution_ids":["https://openalex.org/I73616290"]},{"raw_affiliation_string":"Bioscience Research Division, Liver Cell Signal Transduction Research Unit, Korea Research Institute of Bioscience and Biotechnology, Yusong, Korea","institution_ids":["https://openalex.org/I73616290"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":5990,"currency":"USD","value_usd":5990},"apc_paid":null,"fwci":2.7731,"has_fulltext":false,"cited_by_count":86,"citation_normalized_percentile":{"value":0.90226115,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":89,"max":99},"biblio":{"volume":"19","issue":"30","first_page":"3384","last_page":"3394"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10583","display_name":"Cancer-related Molecular Pathways","score":0.913100004196167,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10583","display_name":"Cancer-related Molecular Pathways","score":0.913100004196167,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10340","display_name":"Hepatitis B Virus Studies","score":0.07890000194311142,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10966","display_name":"Liver physiology and pathology","score":0.0027000000700354576,"subfield":{"id":"https://openalex.org/subfields/2721","display_name":"Hepatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/hepatitis-b-virus-x-protein","display_name":"hepatitis B virus X protein","score":0.9070000052452087},{"id":"https://openalex.org/keywords/p21","display_name":"p21","score":0.9269999861717224},{"id":"https://openalex.org/keywords/p53-independent-pathway","display_name":"p53-independent pathway","score":0.7710000276565552},{"id":"https://openalex.org/keywords/g1-s-transition","display_name":"G1/S transition","score":0.7870000004768372},{"id":"https://openalex.org/keywords/cell-cycle-arrest","display_name":"cell cycle arrest","score":0.8560000061988831},{"id":"https://openalex.org/keywords/hepatocellular-carcinoma","display_name":"hepatocellular carcinoma","score":0.9079999923706055},{"id":"https://openalex.org/keywords/hep3b-cells","display_name":"Hep3B cells","score":0.9079999923706055},{"id":"https://openalex.org/keywords/cdk2","display_name":"CDK2","score":0.8970000147819519},{"id":"https://openalex.org/keywords/cyclin-e","display_name":"cyclin E","score":0.9049999713897705},{"id":"https://openalex.org/keywords/histone-h1-phosphorylation","display_name":"histone H1 phosphorylation","score":0.9599999785423279},{"id":"https://openalex.org/keywords/p21-promoter","display_name":"p21 promoter","score":0.8460000157356262},{"id":"https://openalex.org/keywords/tp53-mutation","display_name":"TP53 mutation","score":0.5419999957084656}],"concepts":[{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.8233767151832581},{"id":"https://openalex.org/C184235292","wikidata":"https://www.wikidata.org/wiki/Q421851","display_name":"Kinase","level":2,"score":0.5645559430122375},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.5348452925682068},{"id":"https://openalex.org/C124320809","wikidata":"https://www.wikidata.org/wiki/Q46292","display_name":"Cyclin-dependent kinase","level":4,"score":0.5333884358406067},{"id":"https://openalex.org/C82495950","wikidata":"https://www.wikidata.org/wiki/Q14911732","display_name":"Cyclin-dependent kinase 2","level":4,"score":0.5207038521766663},{"id":"https://openalex.org/C29537977","wikidata":"https://www.wikidata.org/wiki/Q188941","display_name":"Cell cycle","level":3,"score":0.5174201726913452},{"id":"https://openalex.org/C2780593183","wikidata":"https://www.wikidata.org/wiki/Q6844","display_name":"Hepatitis B virus","level":3,"score":0.5135505199432373},{"id":"https://openalex.org/C16438837","wikidata":"https://www.wikidata.org/wiki/Q5198260","display_name":"Cyclin A","level":5,"score":0.49369415640830994},{"id":"https://openalex.org/C153911025","wikidata":"https://www.wikidata.org/wiki/Q7202","display_name":"Molecular biology","level":1,"score":0.4885493218898773},{"id":"https://openalex.org/C54009773","wikidata":"https://www.wikidata.org/wiki/Q1429031","display_name":"Transfection","level":3,"score":0.46645230054855347},{"id":"https://openalex.org/C94561458","wikidata":"https://www.wikidata.org/wiki/Q24724860","display_name":"Cyclin E","level":5,"score":0.4156540036201477},{"id":"https://openalex.org/C81885089","wikidata":"https://www.wikidata.org/wiki/Q189082","display_name":"Cell culture","level":2,"score":0.397786021232605},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.294522225856781},{"id":"https://openalex.org/C159047783","wikidata":"https://www.wikidata.org/wiki/Q7215","display_name":"Virology","level":1,"score":0.2901443839073181},{"id":"https://openalex.org/C97029542","wikidata":"https://www.wikidata.org/wiki/Q281417","display_name":"Protein kinase A","level":3,"score":0.28100156784057617},{"id":"https://openalex.org/C190283241","wikidata":"https://www.wikidata.org/wiki/Q14599311","display_name":"Apoptosis","level":2,"score":0.21661680936813354},{"id":"https://openalex.org/C2522874641","wikidata":"https://www.wikidata.org/wiki/Q808","display_name":"Virus","level":2,"score":0.1780969798564911},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0802311897277832},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.07091221213340759}],"mesh":[{"descriptor_ui":"D002461","descriptor_name":"Cell Line, Transformed","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004791","descriptor_name":"Enzyme Inhibitors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006515","descriptor_name":"Hepatitis B virus","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D006515","descriptor_name":"Hepatitis B virus","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D006528","descriptor_name":"Carcinoma, Hepatocellular","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011401","descriptor_name":"Promoter Regions, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011518","descriptor_name":"Proto-Oncogene Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D012333","descriptor_name":"RNA, Messenger","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014157","descriptor_name":"Transcription Factors","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D014158","descriptor_name":"Transcription, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014407","descriptor_name":"Tumor Cells, Cultured","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015398","descriptor_name":"Signal Transduction","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015534","descriptor_name":"Trans-Activators","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D015534","descriptor_name":"Trans-Activators","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D015854","descriptor_name":"Up-Regulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015967","descriptor_name":"Gene Expression Regulation, Viral","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016159","descriptor_name":"Tumor Suppressor Protein p53","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D016193","descriptor_name":"G1 Phase","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D016196","descriptor_name":"S Phase","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D016213","descriptor_name":"Cyclins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D016213","descriptor_name":"Cyclins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D017346","descriptor_name":"Protein Serine-Threonine Kinases","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D018844","descriptor_name":"Cyclin-Dependent Kinases","qualifier_ui":"Q000037","qualifier_name":"antagonists & inhibitors","is_major_topic":false},{"descriptor_ui":"D018844","descriptor_name":"Cyclin-Dependent Kinases","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D019927","descriptor_name":"Cyclin E","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D042846","descriptor_name":"CDC2-CDC28 Kinases","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D050759","descriptor_name":"Cyclin-Dependent Kinase Inhibitor p21","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D050783","descriptor_name":"Proto-Oncogene Proteins c-ets","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051357","descriptor_name":"Cyclin-Dependent Kinase 2","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051358","descriptor_name":"Cyclin-Dependent Kinase 4","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D054334","descriptor_name":"Viral Regulatory and Accessory Proteins","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":5,"locations":[{"id":"doi:10.1038/sj.onc.1203674","doi":"https://doi.org/10.1038/sj.onc.1203674","is_oa":false,"landing_page_url":"https://doi.org/10.1038/sj.onc.1203674","pdf_url":null,"source":{"id":"https://openalex.org/S128439998","display_name":"Oncogene","issn_l":"0950-9232","issn":["0950-9232","1476-5594"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319965","host_organization_name":"Springer Nature","host_organization_lineage":["https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Oncogene","raw_type":"journal-article"},{"id":"pmid:10918595","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/10918595","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Oncogene","raw_type":"Journal Article"},{"id":"pmh:oai:http://repository.kribb.re.kr:8080/:201005/5106","doi":null,"is_oa":false,"landing_page_url":"http://hdl.handle.net/201005/5106","pdf_url":null,"source":{"id":"https://openalex.org/S4406922719","display_name":"KRIBB Repository","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"/dspace/upload/original/2969.pdf","raw_type":"Article"},{"id":"pmh:oai:https://repository.kribb.re.kr:201005/5106","doi":null,"is_oa":false,"landing_page_url":"https://repository.kribb.re.kr/handle/201005/5106","pdf_url":null,"source":{"id":"https://openalex.org/S4406922719","display_name":"KRIBB Repository","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"/dspace/upload/original/2969.pdf","raw_type":"Article"},{"id":"pmh:oai:kumel.medlib.dsmc.or.kr:2015.oak/33595","doi":null,"is_oa":true,"landing_page_url":"http://www.nature.com/articles/1203674","pdf_url":null,"source":{"id":"https://openalex.org/S4377196386","display_name":"KUMeL Repository (Keimyung University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I52010207","host_organization_name":"Keimyung University","host_organization_lineage":["https://openalex.org/I52010207"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Article"}],"best_oa_location":{"id":"pmh:oai:kumel.medlib.dsmc.or.kr:2015.oak/33595","doi":null,"is_oa":true,"landing_page_url":"http://www.nature.com/articles/1203674","pdf_url":null,"source":{"id":"https://openalex.org/S4377196386","display_name":"KUMeL Repository (Keimyung University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I52010207","host_organization_name":"Keimyung University","host_organization_lineage":["https://openalex.org/I52010207"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.9763000011444092}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":42,"referenced_works":["https://openalex.org/W55293628","https://openalex.org/W1503116502","https://openalex.org/W1509901905","https://openalex.org/W1965372133","https://openalex.org/W1973047647","https://openalex.org/W1974391793","https://openalex.org/W1977686001","https://openalex.org/W1978922109","https://openalex.org/W1979319210","https://openalex.org/W1983348452","https://openalex.org/W1986150533","https://openalex.org/W1986676942","https://openalex.org/W1987536971","https://openalex.org/W2006937182","https://openalex.org/W2015519364","https://openalex.org/W2015892679","https://openalex.org/W2018183560","https://openalex.org/W2020247808","https://openalex.org/W2024079228","https://openalex.org/W2029506276","https://openalex.org/W2032781689","https://openalex.org/W2034296773","https://openalex.org/W2051316659","https://openalex.org/W2056570769","https://openalex.org/W2060786724","https://openalex.org/W2066975190","https://openalex.org/W2067279573","https://openalex.org/W2070061120","https://openalex.org/W2074114480","https://openalex.org/W2081472291","https://openalex.org/W2085593164","https://openalex.org/W2093019351","https://openalex.org/W2114597712","https://openalex.org/W2123687793","https://openalex.org/W2134812217","https://openalex.org/W2138292652","https://openalex.org/W2144206181","https://openalex.org/W2147242002","https://openalex.org/W2320182093","https://openalex.org/W2328093310","https://openalex.org/W2509077705","https://openalex.org/W2510403669"],"related_works":["https://openalex.org/W6982207668","https://openalex.org/W2079901483","https://openalex.org/W2114343962","https://openalex.org/W2383099120","https://openalex.org/W2107336305","https://openalex.org/W2418004180","https://openalex.org/W2001593061","https://openalex.org/W2018902035","https://openalex.org/W1975873758","https://openalex.org/W1580833874"],"abstract_inverted_index":null,"counts_by_year":[{"year":2023,"cited_by_count":10},{"year":2021,"cited_by_count":2},{"year":2020,"cited_by_count":2},{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":1},{"year":2017,"cited_by_count":4},{"year":2016,"cited_by_count":2},{"year":2015,"cited_by_count":4},{"year":2014,"cited_by_count":3},{"year":2013,"cited_by_count":3},{"year":2012,"cited_by_count":2}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}