{"id":"https://openalex.org/W1966042299","doi":"https://doi.org/10.1016/0027-5107(91)90128-b","title":"Isolation of a menadione-resistant subclone from Chinese hamster lung (CHL) cells in culture","display_name":"Isolation of a menadione-resistant subclone from Chinese hamster lung (CHL) cells in culture","publication_year":1991,"publication_date":"1991-07-01","ids":{"openalex":"https://openalex.org/W1966042299","doi":"https://doi.org/10.1016/0027-5107(91)90128-b","mag":"1966042299","pmid":"https://pubmed.ncbi.nlm.nih.gov/1648663"},"language":"en","primary_location":{"id":"doi:10.1016/0027-5107(91)90128-b","doi":"https://doi.org/10.1016/0027-5107(91)90128-b","is_oa":false,"landing_page_url":"https://doi.org/10.1016/0027-5107(91)90128-b","pdf_url":null,"source":{"id":"https://openalex.org/S4394735698","display_name":"Mutation research. Fundamental and molecular mechanisms of mutagenesis","issn_l":"0027-5107","issn":["0027-5107","1386-1964","1873-135X","1879-2871"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":["anvur-scientific","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5111521753","display_name":"Minoru Sawada","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210151964","display_name":"National Institute of Health Sciences","ror":"https://ror.org/04s629c33","country_code":"JP","type":"facility","lineage":["https://openalex.org/I1333985979","https://openalex.org/I4210151964"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Minoru Sawada","raw_affiliation_strings":["Division of Genetics and Mutagenesis, National Institute of Hygienic Sciences, Tokyo, Japan","Division of Genetics and Mutagenesis, Biological Safety Research Center, National Institute of Hygienic Sciences, 1-18-1 Kamiyoga, Setagaya-ku, Tokyo 158 Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Genetics and Mutagenesis, National Institute of Hygienic Sciences, Tokyo, Japan","institution_ids":["https://openalex.org/I4210151964"]},{"raw_affiliation_string":"Division of Genetics and Mutagenesis, Biological Safety Research Center, National Institute of Hygienic Sciences, 1-18-1 Kamiyoga, Setagaya-ku, Tokyo 158 Japan","institution_ids":["https://openalex.org/I4210151964"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5010967300","display_name":"Toshio Sofuni","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210151964","display_name":"National Institute of Health Sciences","ror":"https://ror.org/04s629c33","country_code":"JP","type":"facility","lineage":["https://openalex.org/I1333985979","https://openalex.org/I4210151964"]}],"countries":["JP"],"is_corresponding":true,"raw_author_name":"Toshio Sofuni","raw_affiliation_strings":["Division of Genetics and Mutagenesis, Biological Safety Research Center, National Institute of Hygienic Sciences, 1-18-1 Kamiyoga, Setagaya-ku, Tokyo 158 Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Genetics and Mutagenesis, Biological Safety Research Center, National Institute of Hygienic Sciences, 1-18-1 Kamiyoga, Setagaya-ku, Tokyo 158 Japan","institution_ids":["https://openalex.org/I4210151964"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5111647327","display_name":"Motoi Ishidate","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210151964","display_name":"National Institute of Health Sciences","ror":"https://ror.org/04s629c33","country_code":"JP","type":"facility","lineage":["https://openalex.org/I1333985979","https://openalex.org/I4210151964"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Motoi Ishidate","raw_affiliation_strings":["Division of Genetics and Mutagenesis, Biological Safety Research Center, National Institute of Hygienic Sciences, 1-18-1 Kamiyoga, Setagaya-ku, Tokyo 158 Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Genetics and Mutagenesis, Biological Safety Research Center, National Institute of Hygienic Sciences, 1-18-1 Kamiyoga, Setagaya-ku, Tokyo 158 Japan","institution_ids":["https://openalex.org/I4210151964"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5010967300"],"corresponding_institution_ids":["https://openalex.org/I4210151964"],"apc_list":{"value":3380,"currency":"USD","value_usd":3380},"apc_paid":null,"fwci":0.4174,"has_fulltext":false,"cited_by_count":8,"citation_normalized_percentile":{"value":0.56102646,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"249","issue":"1","first_page":"7","last_page":"17"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10433","display_name":"Carcinogens and Genotoxicity Assessment","score":0.7929999828338623,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10433","display_name":"Carcinogens and Genotoxicity Assessment","score":0.7929999828338623,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12356","display_name":"Bioactive Compounds and Antitumor Agents","score":0.19460000097751617,"subfield":{"id":"https://openalex.org/subfields/3005","display_name":"Toxicology"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10375","display_name":"Pharmacogenetics and Drug Metabolism","score":0.003700000001117587,"subfield":{"id":"https://openalex.org/subfields/3004","display_name":"Pharmacology"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/chinese-hamster-lung-cells","display_name":"Chinese hamster lung cells","score":0.902999997138977},{"id":"https://openalex.org/keywords/mnng-mutagenesis","display_name":"MNNG mutagenesis","score":0.796999990940094},{"id":"https://openalex.org/keywords/nadph-cytochrome-p450-reductase","display_name":"NADPH-cytochrome P450 reductase","score":0.9380000233650208},{"id":"https://openalex.org/keywords/reductive-activation","display_name":"reductive activation","score":0.7940000295639038},{"id":"https://openalex.org/keywords/chromosomal-abnormalities","display_name":"chromosomal abnormalities","score":0.8539999723434448},{"id":"https://openalex.org/keywords/chromosome-loss","display_name":"chromosome loss","score":0.7599999904632568},{"id":"https://openalex.org/keywords/superoxide-dismutase","display_name":"superoxide dismutase","score":0.8450000286102295},{"id":"https://openalex.org/keywords/catalase","display_name":"catalase","score":0.996999979019165},{"id":"https://openalex.org/keywords/doxorubicin","display_name":"doxorubicin","score":0.7850000262260437},{"id":"https://openalex.org/keywords/mitomycin-c","display_name":"mitomycin C","score":0.9599999785423279},{"id":"https://openalex.org/keywords/drug-resistance","display_name":"drug resistance","score":0.38199999928474426}],"concepts":[{"id":"https://openalex.org/C2781095387","wikidata":"https://www.wikidata.org/wiki/Q192471","display_name":"Menadione","level":3,"score":0.945569634437561},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.685845673084259},{"id":"https://openalex.org/C2777755551","wikidata":"https://www.wikidata.org/wiki/Q2539773","display_name":"Chinese hamster","level":3,"score":0.6682693362236023},{"id":"https://openalex.org/C153911025","wikidata":"https://www.wikidata.org/wiki/Q7202","display_name":"Molecular biology","level":1,"score":0.6309974193572998},{"id":"https://openalex.org/C81885089","wikidata":"https://www.wikidata.org/wiki/Q189082","display_name":"Cell culture","level":2,"score":0.4736432135105133},{"id":"https://openalex.org/C2778575167","wikidata":"https://www.wikidata.org/wiki/Q6573","display_name":"Hamster","level":2,"score":0.461834192276001},{"id":"https://openalex.org/C134651460","wikidata":"https://www.wikidata.org/wiki/Q3100717","display_name":"Reductase","level":3,"score":0.4444385766983032},{"id":"https://openalex.org/C2778979269","wikidata":"https://www.wikidata.org/wiki/Q106951292","display_name":"Catalase","level":3,"score":0.4293183982372284},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.27951323986053467},{"id":"https://openalex.org/C181199279","wikidata":"https://www.wikidata.org/wiki/Q8047","display_name":"Enzyme","level":2,"score":0.26941680908203125},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.22942611575126648}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002470","descriptor_name":"Cell Survival","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D002478","descriptor_name":"Cells, Cultured","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002869","descriptor_name":"Chromosome Aberrations","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002871","descriptor_name":"Chromosome Banding","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003412","descriptor_name":"Cricetulus","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004317","descriptor_name":"Doxorubicin","qualifier_ui":"Q000633","qualifier_name":"toxicity","is_major_topic":false},{"descriptor_ui":"D005038","descriptor_name":"Ethylnitrosourea","qualifier_ui":"Q000633","qualifier_name":"toxicity","is_major_topic":false},{"descriptor_ui":"D006224","descriptor_name":"Cricetinae","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007621","descriptor_name":"Karyotyping","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008168","descriptor_name":"Lung","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":false},{"descriptor_ui":"D008168","descriptor_name":"Lung","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D008769","descriptor_name":"Methylnitronitrosoguanidine","qualifier_ui":"Q000633","qualifier_name":"toxicity","is_major_topic":false},{"descriptor_ui":"D008937","descriptor_name":"Mitomycins","qualifier_ui":"Q000633","qualifier_name":"toxicity","is_major_topic":false},{"descriptor_ui":"D009251","descriptor_name":"NADPH-Ferrihemoprotein Reductase","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D009285","descriptor_name":"Naphthoquinones","qualifier_ui":"Q000633","qualifier_name":"toxicity","is_major_topic":false},{"descriptor_ui":"D013481","descriptor_name":"Superoxides","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014812","descriptor_name":"Vitamin K","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D014812","descriptor_name":"Vitamin K","qualifier_ui":"Q000633","qualifier_name":"toxicity","is_major_topic":true},{"descriptor_ui":"D016296","descriptor_name":"Mutagenesis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016685","descriptor_name":"Mitomycin","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1016/0027-5107(91)90128-b","doi":"https://doi.org/10.1016/0027-5107(91)90128-b","is_oa":false,"landing_page_url":"https://doi.org/10.1016/0027-5107(91)90128-b","pdf_url":null,"source":{"id":"https://openalex.org/S4394735698","display_name":"Mutation research. Fundamental and molecular mechanisms of mutagenesis","issn_l":"0027-5107","issn":["0027-5107","1386-1964","1873-135X","1879-2871"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":["anvur-scientific","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis","raw_type":"journal-article"},{"id":"pmid:1648663","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/1648663","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Mutation research","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.9391000270843506}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":30,"referenced_works":["https://openalex.org/W191793640","https://openalex.org/W1559871277","https://openalex.org/W1583228069","https://openalex.org/W1595656597","https://openalex.org/W1684030580","https://openalex.org/W1828898949","https://openalex.org/W1896627455","https://openalex.org/W1982413261","https://openalex.org/W1992355243","https://openalex.org/W1997836359","https://openalex.org/W2033276907","https://openalex.org/W2035872589","https://openalex.org/W2053118773","https://openalex.org/W2053536319","https://openalex.org/W2056603482","https://openalex.org/W2067345418","https://openalex.org/W2076315300","https://openalex.org/W2094416050","https://openalex.org/W2094779562","https://openalex.org/W2118326935","https://openalex.org/W2128635872","https://openalex.org/W2282054059","https://openalex.org/W2334836450","https://openalex.org/W2743736005","https://openalex.org/W6607821507","https://openalex.org/W6637720661","https://openalex.org/W6638598891","https://openalex.org/W6639692782","https://openalex.org/W6669610049","https://openalex.org/W6674083197"],"related_works":["https://openalex.org/W2066846243","https://openalex.org/W2079585537","https://openalex.org/W1908832138","https://openalex.org/W7220737174","https://openalex.org/W2017521178","https://openalex.org/W1607969536","https://openalex.org/W2062250501","https://openalex.org/W1963546730","https://openalex.org/W2031919974","https://openalex.org/W2047168052"],"abstract_inverted_index":null,"counts_by_year":[],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}