{"id":"https://openalex.org/W1965969578","doi":"https://doi.org/10.1089/jmf.2012.0102","title":"Anti-Inflammatory and Anti-Ulcer Activities of Carvacrol, a Monoterpene Present in the Essential Oil of Oregano","display_name":"Anti-Inflammatory and Anti-Ulcer Activities of Carvacrol, a Monoterpene Present in the Essential Oil of Oregano","publication_year":2012,"publication_date":"2012-08-14","ids":{"openalex":"https://openalex.org/W1965969578","doi":"https://doi.org/10.1089/jmf.2012.0102","mag":"1965969578","pmid":"https://pubmed.ncbi.nlm.nih.gov/22892022"},"language":"en","primary_location":{"id":"doi:10.1089/jmf.2012.0102","doi":"https://doi.org/10.1089/jmf.2012.0102","is_oa":false,"landing_page_url":"https://doi.org/10.1089/jmf.2012.0102","pdf_url":null,"source":{"id":"https://openalex.org/S78718175","display_name":"Journal of Medicinal Food","issn_l":"1096-620X","issn":["1096-620X","1557-7600"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","jufo-1","kci-registered","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320443","host_organization_name":"Mary Ann Liebert, Inc.","host_organization_lineage":["https://openalex.org/P4310320443","https://openalex.org/P4310320017"],"host_organization_lineage_names":["Mary Ann Liebert, Inc.","SAGE Publishing"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Medicinal Food","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5082482657","display_name":"Francilene V. Silva","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I3121799822","display_name":"Universidade Federal do Piau\u00ed","ror":"https://ror.org/00kwnx126","country_code":"BR","type":"education","lineage":["https://openalex.org/I3121799822"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Francilene V. Silva","raw_affiliation_strings":["Medicinal Plants Research Center, Federal University of Piau\u00ed, Teresina, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Medicinal Plants Research Center, Federal University of Piau\u00ed, Teresina, Brazil","institution_ids":["https://openalex.org/I3121799822"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5031080027","display_name":"Adriana Gibara Guimar\u00e3es","orcid":"https://orcid.org/0000-0003-1643-5642","observed_orcids":["https://orcid.org/0000-0003-1643-5642"]},"institutions":[{"id":"https://openalex.org/I190085865","display_name":"Universidade Federal de Sergipe","ror":"https://ror.org/028ka0n85","country_code":"BR","type":"education","lineage":["https://openalex.org/I190085865"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Adriana G. Guimar\u00e3es","raw_affiliation_strings":["Departament of Physiology, Federal University of Sergipe, Aracaju, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departament of Physiology, Federal University of Sergipe, Aracaju, Brazil","institution_ids":["https://openalex.org/I190085865"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5052717646","display_name":"Elayne R.S. Silva","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I3121799822","display_name":"Universidade Federal do Piau\u00ed","ror":"https://ror.org/00kwnx126","country_code":"BR","type":"education","lineage":["https://openalex.org/I3121799822"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Elayne R.S. Silva","raw_affiliation_strings":["Medicinal Plants Research Center, Federal University of Piau\u00ed, Teresina, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Medicinal Plants Research Center, Federal University of Piau\u00ed, Teresina, Brazil","institution_ids":["https://openalex.org/I3121799822"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5046642643","display_name":"Benedito Pereira de Sousa Neto","orcid":"https://orcid.org/0000-0001-5287-5034","observed_orcids":["https://orcid.org/0000-0001-5287-5034"]},"institutions":[{"id":"https://openalex.org/I3121799822","display_name":"Universidade Federal do Piau\u00ed","ror":"https://ror.org/00kwnx126","country_code":"BR","type":"education","lineage":["https://openalex.org/I3121799822"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Benedito P. Sousa-Neto","raw_affiliation_strings":["Medicinal Plants Research Center, Federal University of Piau\u00ed, Teresina, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Medicinal Plants Research Center, Federal University of Piau\u00ed, Teresina, Brazil","institution_ids":["https://openalex.org/I3121799822"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5036198928","display_name":"Fl\u00e1via Danniele Frota Machado","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I3121799822","display_name":"Universidade Federal do Piau\u00ed","ror":"https://ror.org/00kwnx126","country_code":"BR","type":"education","lineage":["https://openalex.org/I3121799822"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Fl\u00e1via D.F. Machado","raw_affiliation_strings":["Medicinal Plants Research Center, Federal University of Piau\u00ed, Teresina, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Medicinal Plants Research Center, Federal University of Piau\u00ed, Teresina, Brazil","institution_ids":["https://openalex.org/I3121799822"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5072217846","display_name":"Lucindo Jos\u00e9 Quintans\u2010J\u00fanior","orcid":"https://orcid.org/0000-0001-5155-938X","observed_orcids":["https://orcid.org/0000-0001-5155-938X"]},"institutions":[{"id":"https://openalex.org/I190085865","display_name":"Universidade Federal de Sergipe","ror":"https://ror.org/028ka0n85","country_code":"BR","type":"education","lineage":["https://openalex.org/I190085865"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Lucindo J. Quintans-J\u00fanior","raw_affiliation_strings":["Departament of Physiology, Federal University of Sergipe, Aracaju, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departament of Physiology, Federal University of Sergipe, Aracaju, Brazil","institution_ids":["https://openalex.org/I190085865"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5020071575","display_name":"Daniel Dias Rufino Arcanjo","orcid":"https://orcid.org/0000-0001-7021-2744","observed_orcids":["https://orcid.org/0000-0001-7021-2744"]},"institutions":[{"id":"https://openalex.org/I3121799822","display_name":"Universidade Federal do Piau\u00ed","ror":"https://ror.org/00kwnx126","country_code":"BR","type":"education","lineage":["https://openalex.org/I3121799822"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Daniel D.R. Arcanjo","raw_affiliation_strings":["Medicinal Plants Research Center, Federal University of Piau\u00ed, Teresina, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Medicinal Plants Research Center, Federal University of Piau\u00ed, Teresina, Brazil","institution_ids":["https://openalex.org/I3121799822"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5085251512","display_name":"Francisco de Assis Oliveira","orcid":"https://orcid.org/0000-0002-3995-7614","observed_orcids":["https://orcid.org/0000-0002-3995-7614"]},"institutions":[{"id":"https://openalex.org/I3121799822","display_name":"Universidade Federal do Piau\u00ed","ror":"https://ror.org/00kwnx126","country_code":"BR","type":"education","lineage":["https://openalex.org/I3121799822"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Francisco A. Oliveira","raw_affiliation_strings":["Medicinal Plants Research Center, Federal University of Piau\u00ed, Teresina, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Medicinal Plants Research Center, Federal University of Piau\u00ed, Teresina, Brazil","institution_ids":["https://openalex.org/I3121799822"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5113601340","display_name":"Rita C. M. Oliveira","orcid":"https://orcid.org/0000-0003-1669-4628","observed_orcids":["https://orcid.org/0000-0003-1669-4628"]},"institutions":[{"id":"https://openalex.org/I3121799822","display_name":"Universidade Federal do Piau\u00ed","ror":"https://ror.org/00kwnx126","country_code":"BR","type":"education","lineage":["https://openalex.org/I3121799822"]}],"countries":["BR"],"is_corresponding":true,"raw_author_name":"Rita C.M. Oliveira","raw_affiliation_strings":["Medicinal Plants Research Center, Federal University of Piau\u00ed, Teresina, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Medicinal Plants Research Center, Federal University of Piau\u00ed, Teresina, Brazil","institution_ids":["https://openalex.org/I3121799822"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5113601340"],"corresponding_institution_ids":["https://openalex.org/I3121799822"],"apc_list":null,"apc_paid":null,"fwci":9.2585,"has_fulltext":false,"cited_by_count":130,"citation_normalized_percentile":{"value":0.98106353,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":98,"max":99},"biblio":{"volume":"15","issue":"11","first_page":"984","last_page":"991"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T14521","display_name":"Medicinal Plant Research","score":0.4458000063896179,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T14521","display_name":"Medicinal Plant Research","score":0.4458000063896179,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10225","display_name":"Essential Oils and Antimicrobial Activity","score":0.3582000136375427,"subfield":{"id":"https://openalex.org/subfields/1106","display_name":"Food Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11613","display_name":"Phytochemistry and Biological Activities","score":0.10700000077486038,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/carvacrol","display_name":"carvacrol","score":1.0},{"id":"https://openalex.org/keywords/oregano-essential-oil","display_name":"oregano essential oil","score":0.921999990940094},{"id":"https://openalex.org/keywords/anti-inflammatory-activity","display_name":"anti-inflammatory activity","score":0.8980000019073486},{"id":"https://openalex.org/keywords/antiulcer-activity","display_name":"antiulcer activity","score":0.9649999737739563},{"id":"https://openalex.org/keywords/paw-edema","display_name":"paw edema","score":0.7390000224113464},{"id":"https://openalex.org/keywords/substance-p","display_name":"substance P","score":0.5580000281333923},{"id":"https://openalex.org/keywords/arachidonic-acid","display_name":"arachidonic acid","score":0.9319999814033508},{"id":"https://openalex.org/keywords/gastric-lesions","display_name":"gastric lesions","score":0.5899999737739563},{"id":"https://openalex.org/keywords/acetic-acid-induced-ulcer","display_name":"acetic acid-induced ulcer","score":0.8450000286102295},{"id":"https://openalex.org/keywords/prostanoids","display_name":"prostanoids","score":0.8690000176429749},{"id":"https://openalex.org/keywords/inflammatory-mediators","display_name":"inflammatory mediators","score":0.8050000071525574},{"id":"https://openalex.org/keywords/cyproheptadine","display_name":"cyproheptadine","score":0.7490000128746033},{"id":"https://openalex.org/keywords/ruthenium-red","display_name":"ruthenium red","score":0.7319999933242798},{"id":"https://openalex.org/keywords/indomethacin","display_name":"indomethacin","score":0.8140000104904175}],"concepts":[{"id":"https://openalex.org/C2780676017","wikidata":"https://www.wikidata.org/wiki/Q225543","display_name":"Carvacrol","level":3,"score":0.8584749698638916},{"id":"https://openalex.org/C2780886150","wikidata":"https://www.wikidata.org/wiki/Q152234","display_name":"Edema","level":2,"score":0.6895571947097778},{"id":"https://openalex.org/C2777671706","wikidata":"https://www.wikidata.org/wiki/Q32528","display_name":"Monoterpene","level":2,"score":0.643439531326294},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.6309949159622192},{"id":"https://openalex.org/C2778078955","wikidata":"https://www.wikidata.org/wiki/Q407699","display_name":"Arachidonic acid","level":3,"score":0.5263922214508057},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.5091935992240906},{"id":"https://openalex.org/C1122143","wikidata":"https://www.wikidata.org/wiki/Q61233","display_name":"Histamine","level":2,"score":0.48769816756248474},{"id":"https://openalex.org/C2777278459","wikidata":"https://www.wikidata.org/wiki/Q170885","display_name":"Essential oil","level":2,"score":0.4576687812805176},{"id":"https://openalex.org/C2778206117","wikidata":"https://www.wikidata.org/wiki/Q417884","display_name":"Cyproheptadine","level":4,"score":0.4444545805454254},{"id":"https://openalex.org/C31903555","wikidata":"https://www.wikidata.org/wiki/Q1637030","display_name":"Food science","level":1,"score":0.2944754362106323},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.254843145608902},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.2537185251712799},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.14462006092071533},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.10154911875724792},{"id":"https://openalex.org/C181199279","wikidata":"https://www.wikidata.org/wiki/Q8047","display_name":"Enzyme","level":2,"score":0.06974828243255615},{"id":"https://openalex.org/C2775864247","wikidata":"https://www.wikidata.org/wiki/Q167934","display_name":"Serotonin","level":3,"score":0.0}],"mesh":[{"descriptor_ui":"D000081007","descriptor_name":"Cymenes","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000893","descriptor_name":"Anti-Inflammatory Agents","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D000897","descriptor_name":"Anti-Ulcer Agents","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D004487","descriptor_name":"Edema","qualifier_ui":"Q000139","qualifier_name":"chemically induced","is_major_topic":false},{"descriptor_ui":"D004487","descriptor_name":"Edema","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007213","descriptor_name":"Indomethacin","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":false},{"descriptor_ui":"D007249","descriptor_name":"Inflammation","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009822","descriptor_name":"Oils, Volatile","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D012430","descriptor_name":"Ruthenium Red","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D013276","descriptor_name":"Stomach Ulcer","qualifier_ui":"Q000139","qualifier_name":"chemically induced","is_major_topic":false},{"descriptor_ui":"D013276","descriptor_name":"Stomach Ulcer","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D013373","descriptor_name":"Substance P","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":false},{"descriptor_ui":"D013755","descriptor_name":"Tetradecanoylphorbol Acetate","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":false},{"descriptor_ui":"D013755","descriptor_name":"Tetradecanoylphorbol Acetate","qualifier_ui":"Q000031","qualifier_name":"analogs & derivatives","is_major_topic":false},{"descriptor_ui":"D016718","descriptor_name":"Arachidonic Acid","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":false},{"descriptor_ui":"D017208","descriptor_name":"Rats, Wistar","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D031341","descriptor_name":"Origanum","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D039821","descriptor_name":"Monoterpenes","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051381","descriptor_name":"Rats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1089/jmf.2012.0102","doi":"https://doi.org/10.1089/jmf.2012.0102","is_oa":false,"landing_page_url":"https://doi.org/10.1089/jmf.2012.0102","pdf_url":null,"source":{"id":"https://openalex.org/S78718175","display_name":"Journal of Medicinal Food","issn_l":"1096-620X","issn":["1096-620X","1557-7600"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","jufo-1","kci-registered","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320443","host_organization_name":"Mary Ann Liebert, Inc.","host_organization_lineage":["https://openalex.org/P4310320443","https://openalex.org/P4310320017"],"host_organization_lineage_names":["Mary Ann Liebert, Inc.","SAGE Publishing"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Medicinal Food","raw_type":"journal-article"},{"id":"pmid:22892022","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/22892022","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of medicinal food","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.9391000270843506}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":45,"referenced_works":["https://openalex.org/W1559586092","https://openalex.org/W1776138295","https://openalex.org/W1883044208","https://openalex.org/W1889805130","https://openalex.org/W1966460928","https://openalex.org/W1968609884","https://openalex.org/W1968688267","https://openalex.org/W1971475173","https://openalex.org/W1975444614","https://openalex.org/W1977681279","https://openalex.org/W1981674944","https://openalex.org/W1981819970","https://openalex.org/W1984127074","https://openalex.org/W1987908785","https://openalex.org/W1993033920","https://openalex.org/W1998724709","https://openalex.org/W2000011073","https://openalex.org/W2015542374","https://openalex.org/W2016750215","https://openalex.org/W2019042498","https://openalex.org/W2020353530","https://openalex.org/W2020539912","https://openalex.org/W2030617634","https://openalex.org/W2033604201","https://openalex.org/W2043790660","https://openalex.org/W2048962022","https://openalex.org/W2056892431","https://openalex.org/W2057363797","https://openalex.org/W2061263799","https://openalex.org/W2070261122","https://openalex.org/W2072377626","https://openalex.org/W2073572798","https://openalex.org/W2083361734","https://openalex.org/W2084994101","https://openalex.org/W2086692058","https://openalex.org/W2087287913","https://openalex.org/W2103494441","https://openalex.org/W2115293219","https://openalex.org/W2125985137","https://openalex.org/W2143821931","https://openalex.org/W2145952115","https://openalex.org/W2155674292","https://openalex.org/W2158686638","https://openalex.org/W2169478020","https://openalex.org/W2170786411"],"related_works":["https://openalex.org/W2057363797","https://openalex.org/W1985668236","https://openalex.org/W2761402274","https://openalex.org/W3163518555","https://openalex.org/W2186619417","https://openalex.org/W2138002999","https://openalex.org/W7120429525","https://openalex.org/W2066515408","https://openalex.org/W2058967017","https://openalex.org/W2120704284"],"abstract_inverted_index":{"This":[0],"study":[1],"reports":[2],"a":[3,13,150],"pharmacological":[4,178],"evaluation":[5],"of":[6,11,17,33,49,143,168,186],"anti-inflammatory":[7],"and":[8,23,28,40,64,75,87,98,111,120,137,146,162,193],"anti-ulcer":[9],"activities":[10],"carvacrol,":[12],"phenolic":[14],"monoterpene":[15],"constituent":[16],"essential":[18],"oils":[19],"produced":[20],"by":[21,36,44,53,81,108,157],"oregano":[22],"other":[24],"several":[25],"aromatic":[26],"plants":[27],"spices,":[29],"in":[30,67,182],"experimental":[31],"models":[32,48],"edema":[34,51,72,79,95,106],"induced":[35,43,52,80,107,156],"different":[37,177],"phlogistic":[38],"agents":[39],"gastric":[41,154,200],"lesions":[42,155],"acetic":[45,159],"acid.":[46],"In":[47,78],"paw":[50],"dextran":[54],"or":[55,131],"histamine,":[56],"carvacrol":[57,84,174],"was":[58],"effective":[59],"at":[60,114,126],"50":[61],"mg/kg":[62],"(46%":[63,97],"35%,":[65],"respectively);":[66],"these":[68],"models,":[69],"cyproheptadine":[70],"reduced":[71,103],"formation":[73,96],"(61%":[74],"43%,":[76],"respectively).":[77,100,139],"substance":[82],"P,":[83],"(100":[85],"mg/kg)":[86,91,148],"ruthenium":[88],"red":[89],"(3":[90],"also":[92],"decreased":[93],"the":[94,104,191,196],"40%,":[99],"Carvacrol":[101,140],"significantly":[102],"ear":[105,118,130,135],"12-O-tetradecanoylphorbol":[109],"acetate":[110],"arachidonic":[112],"acid":[113,158],"0.1":[115],"mg":[116,128,133],"per":[117,129,134],"(43%":[119],"33%,":[121],"respectively),":[122],"similar":[123],"to":[124],"indomethacin":[125],"0.5":[127],"2.0":[132],"(55%":[136],"57%,":[138],"(at":[141],"doses":[142],"25,":[144],"50,":[145],"100":[147],"showed":[149],"healing":[151,197],"capacity":[152],"on":[153,176],"(60%,":[160],"91%,":[161],"81%,":[163],"respectively)":[164],"after":[165],"14":[166],"days":[167],"treatment.":[169],"These":[170],"results":[171],"suggest":[172],"that":[173],"acts":[175],"targets,":[179],"probably":[180],"interfering":[181],"release":[183],"and/or":[184],"synthesis":[185],"inflammatory":[187],"mediators,":[188],"such":[189],"as":[190],"prostanoids,":[192],"thus":[194],"favoring":[195],"process":[198],"for":[199],"ulcers.":[201]},"counts_by_year":[{"year":2026,"cited_by_count":5},{"year":2025,"cited_by_count":11},{"year":2024,"cited_by_count":7},{"year":2023,"cited_by_count":13},{"year":2022,"cited_by_count":13},{"year":2021,"cited_by_count":10},{"year":2020,"cited_by_count":13},{"year":2019,"cited_by_count":12},{"year":2018,"cited_by_count":9},{"year":2017,"cited_by_count":6},{"year":2016,"cited_by_count":5},{"year":2015,"cited_by_count":7},{"year":2014,"cited_by_count":11},{"year":2013,"cited_by_count":8}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2016-06-24T00:00:00"}