{"id":"https://openalex.org/W1965763935","doi":"https://doi.org/10.1097/01.jcp.0000104912.75206.2b","title":"The Effect of Vitamin E Treatment on Tardive Dyskinesia and Blood Superoxide Dismutase","display_name":"The Effect of Vitamin E Treatment on Tardive Dyskinesia and Blood Superoxide Dismutase","publication_year":2004,"publication_date":"2004-02-01","ids":{"openalex":"https://openalex.org/W1965763935","doi":"https://doi.org/10.1097/01.jcp.0000104912.75206.2b","mag":"1965763935","pmid":"https://pubmed.ncbi.nlm.nih.gov/14709952"},"language":"en","primary_location":{"id":"doi:10.1097/01.jcp.0000104912.75206.2b","doi":"https://doi.org/10.1097/01.jcp.0000104912.75206.2b","is_oa":false,"landing_page_url":"https://doi.org/10.1097/01.jcp.0000104912.75206.2b","pdf_url":null,"source":{"id":"https://openalex.org/S76849566","display_name":"Journal of Clinical Psychopharmacology","issn_l":"0271-0749","issn":["0271-0749","1533-712X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Clinical Psychopharmacology","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5100720859","display_name":"Xiang Yang Zhang","orcid":"https://orcid.org/0000-0001-5762-7515","observed_orcids":["https://orcid.org/0000-0001-5762-7515"]},"institutions":[{"id":"https://openalex.org/I20231570","display_name":"Peking University","ror":"https://ror.org/02v51f717","country_code":"CN","type":"education","lineage":["https://openalex.org/I20231570"]},{"id":"https://openalex.org/I4210147103","display_name":"Beijing HuiLongGuan Hospital","ror":"https://ror.org/03wgqqb38","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210110145","https://openalex.org/I4210135108","https://openalex.org/I4210147103"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Xiang Yang Zhang","raw_affiliation_strings":["Institute of Mental Health, Peking University, 100083 Beijing, China; dagger Beijing Hui-Long-Guan Hospital, 100096 Beijing, China","Beijing Hui-Long-Guan Hospital, 100096 Beijing, China","Institute of Mental Health, Peking University, 100083 Beijing, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Mental Health, Peking University, 100083 Beijing, China; dagger Beijing Hui-Long-Guan Hospital, 100096 Beijing, China","institution_ids":["https://openalex.org/I20231570","https://openalex.org/I4210147103"]},{"raw_affiliation_string":"Beijing Hui-Long-Guan Hospital, 100096 Beijing, China","institution_ids":["https://openalex.org/I4210147103"]},{"raw_affiliation_string":"Institute of Mental Health, Peking University, 100083 Beijing, China","institution_ids":["https://openalex.org/I20231570"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5068033155","display_name":"Dong Zhou","orcid":"https://orcid.org/0000-0002-3289-2168","observed_orcids":["https://orcid.org/0000-0002-3289-2168"]},"institutions":[{"id":"https://openalex.org/I20231570","display_name":"Peking University","ror":"https://ror.org/02v51f717","country_code":"CN","type":"education","lineage":["https://openalex.org/I20231570"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Dong Feng Zhou","raw_affiliation_strings":["Institute of Mental Health, Peking University, 100083 Beijing, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Mental Health, Peking University, 100083 Beijing, China","institution_ids":["https://openalex.org/I20231570"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109962281","display_name":"Lian Yuan Cao","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210147103","display_name":"Beijing HuiLongGuan Hospital","ror":"https://ror.org/03wgqqb38","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210110145","https://openalex.org/I4210135108","https://openalex.org/I4210147103"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Lian Yuan Cao","raw_affiliation_strings":["Beijing Hui-Long-Guan Hospital, 100096 Beijing, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Beijing Hui-Long-Guan Hospital, 100096 Beijing, China","institution_ids":["https://openalex.org/I4210147103"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5061251489","display_name":"Chang Qing Xu","orcid":"https://orcid.org/0000-0002-5524-4550","observed_orcids":["https://orcid.org/0000-0002-5524-4550"]},"institutions":[{"id":"https://openalex.org/I32971472","display_name":"Yale University","ror":"https://ror.org/03v76x132","country_code":"US","type":"education","lineage":["https://openalex.org/I32971472"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Chang Qing Xu","raw_affiliation_strings":["Department of Psychiatry, Yale University School of Medicine, New Haven, CT"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Psychiatry, Yale University School of Medicine, New Haven, CT","institution_ids":["https://openalex.org/I32971472"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110387432","display_name":"Da Chun Chen","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210147103","display_name":"Beijing HuiLongGuan Hospital","ror":"https://ror.org/03wgqqb38","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210110145","https://openalex.org/I4210135108","https://openalex.org/I4210147103"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Da Chun Chen","raw_affiliation_strings":["Beijing Hui-Long-Guan Hospital, 100096 Beijing, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Beijing Hui-Long-Guan Hospital, 100096 Beijing, China","institution_ids":["https://openalex.org/I4210147103"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5113635063","display_name":"Gui Ying Wu","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210147103","display_name":"Beijing HuiLongGuan Hospital","ror":"https://ror.org/03wgqqb38","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210110145","https://openalex.org/I4210135108","https://openalex.org/I4210147103"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Gui Ying Wu","raw_affiliation_strings":["Beijing Hui-Long-Guan Hospital, 100096 Beijing, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Beijing Hui-Long-Guan Hospital, 100096 Beijing, China","institution_ids":["https://openalex.org/I4210147103"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5068033155","https://openalex.org/A5100720859"],"corresponding_institution_ids":["https://openalex.org/I20231570","https://openalex.org/I4210147103"],"apc_list":null,"apc_paid":null,"fwci":3.7343,"has_fulltext":false,"cited_by_count":57,"citation_normalized_percentile":{"value":0.92244023,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":89,"max":98},"biblio":{"volume":"24","issue":"1","first_page":"83","last_page":"86"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10023","display_name":"Schizophrenia research and treatment","score":0.9023000001907349,"subfield":{"id":"https://openalex.org/subfields/2738","display_name":"Psychiatry and Mental health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10023","display_name":"Schizophrenia research and treatment","score":0.9023000001907349,"subfield":{"id":"https://openalex.org/subfields/2738","display_name":"Psychiatry and Mental health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10445","display_name":"Antioxidant Activity and Oxidative Stress","score":0.0430000014603138,"subfield":{"id":"https://openalex.org/subfields/2704","display_name":"Biochemistry"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10085","display_name":"Parkinson's Disease Mechanisms and Treatments","score":0.01679999940097332,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/tardive-dyskinesia","display_name":"tardive dyskinesia","score":0.984000027179718},{"id":"https://openalex.org/keywords/vitamin-e","display_name":"vitamin E","score":0.996999979019165},{"id":"https://openalex.org/keywords/superoxide-dismutase","display_name":"superoxide dismutase","score":0.9980000257492065},{"id":"https://openalex.org/keywords/free-radicals","display_name":"free radicals","score":0.9480000138282776},{"id":"https://openalex.org/keywords/oxidative-stress","display_name":"oxidative stress","score":0.949999988079071},{"id":"https://openalex.org/keywords/abnormal-involuntary-movement-scale","display_name":"Abnormal Involuntary Movement Scale","score":0.9100000262260437},{"id":"https://openalex.org/keywords/antipsychotic-side-effects","display_name":"antipsychotic adverse effects","score":0.746999979019165},{"id":"https://openalex.org/keywords/antioxidant-therapy","display_name":"antioxidant therapy","score":0.6610000133514404}],"concepts":[{"id":"https://openalex.org/C2779158372","wikidata":"https://www.wikidata.org/wiki/Q1546328","display_name":"Tardive dyskinesia","level":3,"score":0.8566325902938843},{"id":"https://openalex.org/C27081682","wikidata":"https://www.wikidata.org/wiki/Q269829","display_name":"Placebo","level":3,"score":0.7944455742835999},{"id":"https://openalex.org/C2775838275","wikidata":"https://www.wikidata.org/wiki/Q410776","display_name":"Superoxide dismutase","level":3,"score":0.7292969226837158},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.6411483287811279},{"id":"https://openalex.org/C2777551382","wikidata":"https://www.wikidata.org/wiki/Q141180","display_name":"Vitamin E","level":3,"score":0.6199010014533997},{"id":"https://openalex.org/C2780405171","wikidata":"https://www.wikidata.org/wiki/Q629444","display_name":"Dyskinesia","level":4,"score":0.5840855836868286},{"id":"https://openalex.org/C2780022331","wikidata":"https://www.wikidata.org/wiki/Q199678","display_name":"Vitamin C","level":2,"score":0.5796039700508118},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.5361648797988892},{"id":"https://openalex.org/C90924648","wikidata":"https://www.wikidata.org/wiki/Q120569","display_name":"Gastroenterology","level":1,"score":0.4769671857357025},{"id":"https://openalex.org/C2776940978","wikidata":"https://www.wikidata.org/wiki/Q34956","display_name":"Vitamin","level":2,"score":0.47029969096183777},{"id":"https://openalex.org/C2986274086","wikidata":"https://www.wikidata.org/wiki/Q199678","display_name":"Ascorbic acid","level":2,"score":0.4597930908203125},{"id":"https://openalex.org/C2992339995","wikidata":"https://www.wikidata.org/wiki/Q133948","display_name":"Free radical scavenger","level":3,"score":0.4463639259338379},{"id":"https://openalex.org/C2778760513","wikidata":"https://www.wikidata.org/wiki/Q24773045","display_name":"Glutathione peroxidase","level":4,"score":0.4212125837802887},{"id":"https://openalex.org/C2776151105","wikidata":"https://www.wikidata.org/wiki/Q898814","display_name":"Oxidative stress","level":2,"score":0.35714834928512573},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.3336946666240692},{"id":"https://openalex.org/C2778004101","wikidata":"https://www.wikidata.org/wiki/Q133948","display_name":"Antioxidant","level":2,"score":0.3102966547012329},{"id":"https://openalex.org/C2779734285","wikidata":"https://www.wikidata.org/wiki/Q11085","display_name":"Parkinson's disease","level":3,"score":0.1302972137928009},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.11967676877975464},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.11657756567001343},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.1011522114276886},{"id":"https://openalex.org/C118552586","wikidata":"https://www.wikidata.org/wiki/Q7867","display_name":"Psychiatry","level":1,"score":0.07375410199165344},{"id":"https://openalex.org/C2776412080","wikidata":"https://www.wikidata.org/wiki/Q7431605","display_name":"Schizophrenia (object-oriented programming)","level":2,"score":0.06082823872566223},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.0},{"id":"https://openalex.org/C204787440","wikidata":"https://www.wikidata.org/wiki/Q188504","display_name":"Alternative medicine","level":2,"score":0.0},{"id":"https://openalex.org/C31903555","wikidata":"https://www.wikidata.org/wiki/Q1637030","display_name":"Food science","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002214","descriptor_name":"Capsules","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004311","descriptor_name":"Double-Blind Method","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D004334","descriptor_name":"Drug Administration Schedule","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004409","descriptor_name":"Dyskinesia, Drug-Induced","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D004409","descriptor_name":"Dyskinesia, Drug-Induced","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D004409","descriptor_name":"Dyskinesia, Drug-Induced","qualifier_ui":"Q000208","qualifier_name":"ethnology","is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011863","descriptor_name":"Radioimmunoassay","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012720","descriptor_name":"Severity of Illness Index","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013482","descriptor_name":"Superoxide Dismutase","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D013482","descriptor_name":"Superoxide Dismutase","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D014150","descriptor_name":"Antipsychotic Agents","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":false},{"descriptor_ui":"D014810","descriptor_name":"Vitamin E","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":false},{"descriptor_ui":"D014810","descriptor_name":"Vitamin E","qualifier_ui":"Q000493","qualifier_name":"pharmacokinetics","is_major_topic":false},{"descriptor_ui":"D014810","descriptor_name":"Vitamin E","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D016166","descriptor_name":"Free Radical Scavengers","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":false},{"descriptor_ui":"D016166","descriptor_name":"Free Radical Scavengers","qualifier_ui":"Q000493","qualifier_name":"pharmacokinetics","is_major_topic":false},{"descriptor_ui":"D016166","descriptor_name":"Free Radical Scavengers","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1097/01.jcp.0000104912.75206.2b","doi":"https://doi.org/10.1097/01.jcp.0000104912.75206.2b","is_oa":false,"landing_page_url":"https://doi.org/10.1097/01.jcp.0000104912.75206.2b","pdf_url":null,"source":{"id":"https://openalex.org/S76849566","display_name":"Journal of Clinical Psychopharmacology","issn_l":"0271-0749","issn":["0271-0749","1533-712X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Clinical Psychopharmacology","raw_type":"journal-article"},{"id":"pmid:14709952","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/14709952","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of clinical psychopharmacology","raw_type":"Clinical Trial"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":1.0,"display_name":"Good health and well-being"}],"sustainable_development_goals_aurora":[{"id":"https://metadata.un.org/sdg/3","score":0.7699999809265137,"display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/randomized-controlled-trial","display_name":"Randomized Controlled Trial"},{"id":"https://openalex.org/study-designs/clinical-trial","display_name":"Clinical Trial"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":26,"referenced_works":["https://openalex.org/W147183711","https://openalex.org/W1743357450","https://openalex.org/W1967367155","https://openalex.org/W1993896536","https://openalex.org/W1995882283","https://openalex.org/W2013140586","https://openalex.org/W2014746376","https://openalex.org/W2021896307","https://openalex.org/W2037960121","https://openalex.org/W2076193416","https://openalex.org/W2086327997","https://openalex.org/W2091249865","https://openalex.org/W2093417750","https://openalex.org/W2123297201","https://openalex.org/W2125738714","https://openalex.org/W2140606211","https://openalex.org/W2140674517","https://openalex.org/W2142448187","https://openalex.org/W2165122693","https://openalex.org/W2165816410","https://openalex.org/W2263266898","https://openalex.org/W2395252192","https://openalex.org/W2416930921","https://openalex.org/W2417028432","https://openalex.org/W4230950110","https://openalex.org/W4247906778"],"related_works":["https://openalex.org/W1743357450","https://openalex.org/W2152420985","https://openalex.org/W147183711","https://openalex.org/W2395252192","https://openalex.org/W2134917910","https://openalex.org/W2024285057","https://openalex.org/W2400067474","https://openalex.org/W7096716694","https://openalex.org/W2091249865","https://openalex.org/W2624649939"],"abstract_inverted_index":{"Free":[0],"radicals":[1],"may":[2,204,215],"be":[3,205],"involved":[4],"in":[5,35,60,141,193,219],"the":[6,46,61,81,111,139,188,194,199],"pathogenesis":[7],"of":[8,24,38,48,63,76,80,91,187,190,196,201],"tardive":[9,220],"dyskinesia":[10],"(TD).":[11],"Vitamin":[12],"E,":[13,95],"a":[14,36,57,71,88,101],"free":[15,64],"radical":[16],"scavenger,":[17],"has":[18],"been":[19],"reported":[20],"to":[21,31,44,86,100,207,210],"improve":[22],"symptoms":[23],"TD.":[25,197],"The":[26,135],"present":[27],"study":[28,75],"was":[29,146],"designed":[30],"replicate":[32],"this":[33],"finding":[34],"group":[37],"Chinese":[39],"patients":[40,82],"with":[41,68,149,154,167,176],"TD,":[42],"and":[43,96,121,132],"examine":[45],"effect":[47],"vitamin":[49,77,94,150,168,191,202],"E":[50,151,169,192,203],"treatment":[51,152,166,178,195],"on":[52],"blood":[53],"superoxide":[54],"dismutase":[55],"(SOD),":[56],"critical":[58],"enzyme":[59],"detoxification":[62],"radicals.":[65],"Forty-one":[66],"inpatients":[67],"TD":[69],"completed":[70],"double-blind,":[72],"placebo-controlled,":[73],"parallel-group":[74],"E.":[78],"Twenty-two":[79],"were":[83,98,107,126,162],"randomly":[84],"assigned":[85,99],"receive":[87],"fixed":[89],"dose":[90],"1200":[92],"IU/d":[93],"19":[97],"placebo":[102,155,177],"for":[103],"12":[104],"weeks.":[105],"Patients":[106],"assessed":[108],"primarily":[109],"using":[110],"Abnormal":[112],"Involuntary":[113],"Movement":[114],"Scale":[115],"(AIMS)":[116],"at":[117],"baseline,":[118],"weeks":[119],"6":[120],"12.":[122],"Blood":[123,159],"SOD":[124,160,212],"levels":[125,161],"measured":[127],"by":[128],"radioimmunometric":[129],"assay":[130],"before":[131],"after":[133,165],"treatment.":[134],"results":[136,183],"showed":[137],"that":[138],"reduction":[140],"AIMS":[142],"score":[143],"from":[144],"baseline":[145],"significantly":[147,163],"higher":[148],"compared":[153],"(45.9%":[156],"vs.":[157],"4.3%).":[158],"increased":[164],"(P":[170,179],"=":[171],"0.001),":[172],"but":[173],"no":[174],"change":[175],"<":[180],"0.05).":[181],"These":[182],"support":[184],"earlier":[185],"findings":[186],"efficacy":[189,200],"Moreover,":[198],"due":[206],"its":[208],"ability":[209],"increase":[211],"level,":[213],"which":[214],"reduce":[216],"oxidative":[217],"injure":[218],"dyskinesia.":[221]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":3},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":4},{"year":2021,"cited_by_count":4},{"year":2019,"cited_by_count":2},{"year":2018,"cited_by_count":1},{"year":2017,"cited_by_count":2},{"year":2016,"cited_by_count":4},{"year":2015,"cited_by_count":3},{"year":2013,"cited_by_count":3},{"year":2012,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}