{"id":"https://openalex.org/W1965628871","doi":"https://doi.org/10.1016/j.bcmd.2013.11.006","title":"Genetic heterogeneity of hemoglobin AEBart's disease: A large cohort data from a single referral center in northeast Thailand","display_name":"Genetic heterogeneity of hemoglobin AEBart's disease: A large cohort data from a single referral center in northeast Thailand","publication_year":2013,"publication_date":"2013-12-05","ids":{"openalex":"https://openalex.org/W1965628871","doi":"https://doi.org/10.1016/j.bcmd.2013.11.006","mag":"1965628871","pmid":"https://pubmed.ncbi.nlm.nih.gov/24314747"},"language":"en","primary_location":{"id":"doi:10.1016/j.bcmd.2013.11.006","doi":"https://doi.org/10.1016/j.bcmd.2013.11.006","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.bcmd.2013.11.006","pdf_url":null,"source":{"id":"https://openalex.org/S183588319","display_name":"Blood Cells Molecules and Diseases","issn_l":"1079-9796","issn":["1079-9796","1096-0961"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Blood Cells, Molecules, and Diseases","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5015770985","display_name":"Attawut Chaibunruang","orcid":"https://orcid.org/0000-0002-2784-2449","observed_orcids":["https://orcid.org/0000-0002-2784-2449"]},"institutions":[{"id":"https://openalex.org/I179193067","display_name":"Khon Kaen University","ror":"https://ror.org/03cq4gr50","country_code":"TH","type":"education","lineage":["https://openalex.org/I179193067"]}],"countries":["TH"],"is_corresponding":false,"raw_author_name":"Attawut Chaibunruang","raw_affiliation_strings":["Centre for Research and Development of Medical Diagnostic Laboratories, Faculty of Associated Medical Sciences, Khon Kaen University, Khon Kaen, Thailand"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Centre for Research and Development of Medical Diagnostic Laboratories, Faculty of Associated Medical Sciences, Khon Kaen University, Khon Kaen, Thailand","institution_ids":["https://openalex.org/I179193067"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5053151571","display_name":"Rossarin Karnpean","orcid":"https://orcid.org/0000-0003-2378-5472","observed_orcids":["https://orcid.org/0000-0003-2378-5472"]},"institutions":[{"id":"https://openalex.org/I179193067","display_name":"Khon Kaen University","ror":"https://ror.org/03cq4gr50","country_code":"TH","type":"education","lineage":["https://openalex.org/I179193067"]},{"id":"https://openalex.org/I72091625","display_name":"Ubon Ratchathani University","ror":"https://ror.org/045nemn19","country_code":"TH","type":"education","lineage":["https://openalex.org/I72091625"]}],"countries":["TH"],"is_corresponding":false,"raw_author_name":"Rossarin Karnpean","raw_affiliation_strings":["Centre for Research and Development of Medical Diagnostic Laboratories, Faculty of Associated Medical Sciences, Khon Kaen University, Khon Kaen, Thailand; College of Medicine and Public Health, Ubon Ratchathani University, Ubon Ratchathani, Thailand","Centre for Research and Development of Medical Diagnostic Laboratories, Faculty of Associated Medical Sciences, Khon Kaen University, Khon Kaen, Thailand","College of Medicine and Public Health, Ubon Ratchathani University, Ubon Ratchathani, Thailand"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Centre for Research and Development of Medical Diagnostic Laboratories, Faculty of Associated Medical Sciences, Khon Kaen University, Khon Kaen, Thailand; College of Medicine and Public Health, Ubon Ratchathani University, Ubon Ratchathani, Thailand","institution_ids":["https://openalex.org/I179193067","https://openalex.org/I72091625"]},{"raw_affiliation_string":"Centre for Research and Development of Medical Diagnostic Laboratories, Faculty of Associated Medical Sciences, Khon Kaen University, Khon Kaen, Thailand","institution_ids":["https://openalex.org/I179193067"]},{"raw_affiliation_string":"College of Medicine and Public Health, Ubon Ratchathani University, Ubon Ratchathani, Thailand","institution_ids":["https://openalex.org/I72091625"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113768805","display_name":"Goonnapa Fucharoen","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I179193067","display_name":"Khon Kaen University","ror":"https://ror.org/03cq4gr50","country_code":"TH","type":"education","lineage":["https://openalex.org/I179193067"]}],"countries":["TH"],"is_corresponding":false,"raw_author_name":"Goonnapa Fucharoen","raw_affiliation_strings":["Centre for Research and Development of Medical Diagnostic Laboratories, Faculty of Associated Medical Sciences, Khon Kaen University, Khon Kaen, Thailand"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Centre for Research and Development of Medical Diagnostic Laboratories, Faculty of Associated Medical Sciences, Khon Kaen University, Khon Kaen, Thailand","institution_ids":["https://openalex.org/I179193067"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5083352272","display_name":"Supan Fucharoen","orcid":"https://orcid.org/0000-0001-9142-5079","observed_orcids":["https://orcid.org/0000-0001-9142-5079"]},"institutions":[{"id":"https://openalex.org/I179193067","display_name":"Khon Kaen University","ror":"https://ror.org/03cq4gr50","country_code":"TH","type":"education","lineage":["https://openalex.org/I179193067"]}],"countries":["TH"],"is_corresponding":true,"raw_author_name":"Supan Fucharoen","raw_affiliation_strings":["Centre for Research and Development of Medical Diagnostic Laboratories, Faculty of Associated Medical Sciences, Khon Kaen University, Khon Kaen, Thailand. Electronic address: supan@kku.ac.th","Centre for Research and Development of Medical Diagnostic Laboratories, Faculty of Associated Medical Sciences, Khon Kaen University, Khon Kaen, Thailand"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Centre for Research and Development of Medical Diagnostic Laboratories, Faculty of Associated Medical Sciences, Khon Kaen University, Khon Kaen, Thailand. Electronic address: supan@kku.ac.th","institution_ids":["https://openalex.org/I179193067"]},{"raw_affiliation_string":"Centre for Research and Development of Medical Diagnostic Laboratories, Faculty of Associated Medical Sciences, Khon Kaen University, Khon Kaen, Thailand","institution_ids":["https://openalex.org/I179193067"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5083352272"],"corresponding_institution_ids":["https://openalex.org/I179193067"],"apc_list":{"value":4030,"currency":"USD","value_usd":4030},"apc_paid":null,"fwci":1.1825,"has_fulltext":false,"cited_by_count":28,"citation_normalized_percentile":{"value":0.76333022,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":87,"max":98},"biblio":{"volume":"52","issue":"4","first_page":"176","last_page":"180"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10554","display_name":"Hemoglobinopathies and Related Disorders","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2716","display_name":"Genetics (clinical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10554","display_name":"Hemoglobinopathies and Related Disorders","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2716","display_name":"Genetics (clinical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11660","display_name":"Blood groups and transfusion","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12094","display_name":"Hemoglobin structure and function","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1303","display_name":"Biochemistry"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/thalassemia-intermedia","display_name":"thalassemia intermedia","score":0.9210000038146973},{"id":"https://openalex.org/keywords/hemoglobin-e","display_name":"hemoglobin E","score":0.7139999866485596},{"id":"https://openalex.org/keywords/alpha-thalassemia","display_name":"alpha-thalassemia","score":0.8560000061988831},{"id":"https://openalex.org/keywords/alpha-globin-gene-deletion","display_name":"alpha-globin gene deletion","score":0.6890000104904175},{"id":"https://openalex.org/keywords/hb-constant-spring","display_name":"Hb Constant Spring","score":0.8519999980926514},{"id":"https://openalex.org/keywords/genetic-heterogeneity","display_name":"genetic heterogeneity","score":0.6129999756813049},{"id":"https://openalex.org/keywords/phenotypic-expression","display_name":"phenotypic expression","score":0.7770000100135803},{"id":"https://openalex.org/keywords/anemia","display_name":"anemia","score":0.722000002861023},{"id":"https://openalex.org/keywords/genetic-counseling","display_name":"genetic counseling","score":0.4690000116825104},{"id":"https://openalex.org/keywords/northeast-thailand","display_name":"Northeast Thailand","score":0.6299999952316284}],"concepts":[{"id":"https://openalex.org/C2777799968","wikidata":"https://www.wikidata.org/wiki/Q185137","display_name":"Thalassemia","level":2,"score":0.7815306186676025},{"id":"https://openalex.org/C135763542","wikidata":"https://www.wikidata.org/wiki/Q106016","display_name":"Genotype","level":3,"score":0.5679298043251038},{"id":"https://openalex.org/C12125453","wikidata":"https://www.wikidata.org/wiki/Q5156837","display_name":"Compound heterozygosity","level":4,"score":0.5140491724014282},{"id":"https://openalex.org/C2778548071","wikidata":"https://www.wikidata.org/wiki/Q288714","display_name":"Alpha-thalassemia","level":4,"score":0.5102858543395996},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.5046559572219849},{"id":"https://openalex.org/C2781217586","wikidata":"https://www.wikidata.org/wiki/Q17022356","display_name":"Hemoglobin E","level":3,"score":0.5030156970024109},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.494811475276947},{"id":"https://openalex.org/C180754005","wikidata":"https://www.wikidata.org/wiki/Q80726","display_name":"Allele","level":3,"score":0.49216264486312866},{"id":"https://openalex.org/C2779668550","wikidata":"https://www.wikidata.org/wiki/Q1642147","display_name":"Hemoglobinopathy","level":3,"score":0.48959025740623474},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.48672226071357727},{"id":"https://openalex.org/C72563966","wikidata":"https://www.wikidata.org/wiki/Q1303415","display_name":"Cohort","level":2,"score":0.45009854435920715},{"id":"https://openalex.org/C2778917026","wikidata":"https://www.wikidata.org/wiki/Q43041","display_name":"Hemoglobin","level":2,"score":0.4252045154571533},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3464961647987366},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.3052014410495758},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.13776734471321106}],"mesh":[{"descriptor_ui":"D004252","descriptor_name":"DNA Mutational Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004843","descriptor_name":"Epistasis, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005838","descriptor_name":"Genotype","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006446","descriptor_name":"Hemoglobin E","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D006446","descriptor_name":"Hemoglobin E","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D006447","descriptor_name":"Hemoglobin H","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D006447","descriptor_name":"Hemoglobin H","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D006455","descriptor_name":"Hemoglobins, Abnormal","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D006455","descriptor_name":"Hemoglobins, Abnormal","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010641","descriptor_name":"Phenotype","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013785","descriptor_name":"Thailand","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013789","descriptor_name":"Thalassemia","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":true},{"descriptor_ui":"D013789","descriptor_name":"Thalassemia","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D017353","descriptor_name":"Gene Deletion","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018740","descriptor_name":"Genetic Heterogeneity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D023061","descriptor_name":"Gene Order","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D056726","descriptor_name":"Genetic Association Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1016/j.bcmd.2013.11.006","doi":"https://doi.org/10.1016/j.bcmd.2013.11.006","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.bcmd.2013.11.006","pdf_url":null,"source":{"id":"https://openalex.org/S183588319","display_name":"Blood Cells Molecules and Diseases","issn_l":"1079-9796","issn":["1079-9796","1096-0961"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Blood Cells, Molecules, and Diseases","raw_type":"journal-article"},{"id":"pmid:24314747","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/24314747","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Blood cells, molecules & diseases","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.9537000060081482,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":22,"referenced_works":["https://openalex.org/W1604503695","https://openalex.org/W1863308272","https://openalex.org/W1965381255","https://openalex.org/W1978047614","https://openalex.org/W1981114703","https://openalex.org/W1982562659","https://openalex.org/W1991251847","https://openalex.org/W2017871710","https://openalex.org/W2029121843","https://openalex.org/W2038597617","https://openalex.org/W2043510177","https://openalex.org/W2043970613","https://openalex.org/W2056160047","https://openalex.org/W2077113396","https://openalex.org/W2093633744","https://openalex.org/W2094742463","https://openalex.org/W2108553887","https://openalex.org/W2109572087","https://openalex.org/W2134574517","https://openalex.org/W2141533237","https://openalex.org/W2152670967","https://openalex.org/W2159019696"],"related_works":["https://openalex.org/W2056160047","https://openalex.org/W2995951946","https://openalex.org/W2795657820","https://openalex.org/W4399929238","https://openalex.org/W2030724515","https://openalex.org/W2984549154","https://openalex.org/W1982562659","https://openalex.org/W23732109","https://openalex.org/W1991251847","https://openalex.org/W1844789861"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":3},{"year":2023,"cited_by_count":3},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":6},{"year":2019,"cited_by_count":4},{"year":2018,"cited_by_count":1},{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":2},{"year":2015,"cited_by_count":2},{"year":2014,"cited_by_count":1}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2016-06-24T00:00:00"}