{"id":"https://openalex.org/W1965620749","doi":"https://doi.org/10.1016/s0889-857x(05)70191-5","title":"Role of Estrogens in the Management of Postmenopausal Bone Loss","display_name":"Role of Estrogens in the Management of Postmenopausal Bone Loss","publication_year":2001,"publication_date":"2001-02-01","ids":{"openalex":"https://openalex.org/W1965620749","doi":"https://doi.org/10.1016/s0889-857x(05)70191-5","mag":"1965620749","pmid":"https://pubmed.ncbi.nlm.nih.gov/11285992"},"language":"en","primary_location":{"id":"doi:10.1016/s0889-857x(05)70191-5","doi":"https://doi.org/10.1016/s0889-857x(05)70191-5","is_oa":false,"landing_page_url":"https://doi.org/10.1016/s0889-857x(05)70191-5","pdf_url":null,"source":{"id":"https://openalex.org/S28431432","display_name":"Rheumatic Disease Clinics of North America","issn_l":"0889-857X","issn":["0889-857X","1558-3163"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Rheumatic Disease Clinics of North America","raw_type":"journal-article"},"volume":null,"type":"review","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5037448661","display_name":"John Christopher Gallagher","orcid":"https://orcid.org/0000-0002-5129-9183","observed_orcids":["https://orcid.org/0000-0002-5129-9183"]},"institutions":[{"id":"https://openalex.org/I2800482329","display_name":"CHI Health Creighton University Medical Center - Bergan Mercy","ror":"https://ror.org/03z1w3b90","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2800482329","https://openalex.org/I2802665030","https://openalex.org/I2802797007"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"J. Christopher Gallagher","raw_affiliation_strings":["Bone Metabolism Unit, Creighton University Medical Center, St. Joseph's Hospital, Omaha, Nebraska, USA. jcg@creighton.edu","Bone Metabolism Unit, Creighton University Medical Center, St. Joseph's Hospital, Omaha, Nebraska, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Bone Metabolism Unit, Creighton University Medical Center, St. Joseph's Hospital, Omaha, Nebraska, USA. jcg@creighton.edu","institution_ids":["https://openalex.org/I2800482329"]},{"raw_affiliation_string":"Bone Metabolism Unit, Creighton University Medical Center, St. Joseph's Hospital, Omaha, Nebraska, USA","institution_ids":["https://openalex.org/I2800482329"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5037448661"],"corresponding_institution_ids":["https://openalex.org/I2800482329"],"apc_list":{"value":3500,"currency":"USD","value_usd":3500},"apc_paid":null,"fwci":1.2184,"has_fulltext":false,"cited_by_count":62,"citation_normalized_percentile":{"value":0.76444444,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":97},"biblio":{"volume":"27","issue":"1","first_page":"143","last_page":"162"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10694","display_name":"Menopause: Health Impacts and Treatments","score":0.9092000126838684,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10694","display_name":"Menopause: Health Impacts and Treatments","score":0.9092000126838684,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10071","display_name":"Bone health and osteoporosis research","score":0.0851999968290329,"subfield":{"id":"https://openalex.org/subfields/2732","display_name":"Orthopedics and Sports Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10756","display_name":"Estrogen and related hormone effects","score":0.00139999995008111,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/estrogen","display_name":"estrogen","score":0.8569999933242798},{"id":"https://openalex.org/keywords/postmenopausal-bone-loss","display_name":"postmenopausal bone loss","score":0.9340000152587891},{"id":"https://openalex.org/keywords/hormone-replacement-therapy","display_name":"hormone replacement therapy","score":0.7879999876022339},{"id":"https://openalex.org/keywords/osteoporosis-prevention","display_name":"osteoporosis prevention","score":0.9369999766349792},{"id":"https://openalex.org/keywords/estrogen-deficiency","display_name":"estrogen deficiency","score":0.7889999747276306},{"id":"https://openalex.org/keywords/bone-remodeling","display_name":"bone remodeling","score":0.9660000205039978},{"id":"https://openalex.org/keywords/low-dose-estrogen","display_name":"low-dose estrogen","score":0.7099999785423279},{"id":"https://openalex.org/keywords/calcium-and-vitamin-d-supplementation","display_name":"calcium and vitamin D supplementation","score":0.6589999794960022},{"id":"https://openalex.org/keywords/exercise","display_name":"physical activity","score":0.9169999957084656},{"id":"https://openalex.org/keywords/corticosteroid-induced-osteoporosis","display_name":"corticosteroid-induced osteoporosis","score":0.9480000138282776},{"id":"https://openalex.org/keywords/treatment-adherence","display_name":"medication adherence","score":0.6299999952316284},{"id":"https://openalex.org/keywords/breast-cancer-risk","display_name":"breast cancer risk","score":0.6039999723434448},{"id":"https://openalex.org/keywords/endometrial-cancer-risk","display_name":"endometrial cancer risk","score":0.8560000061988831},{"id":"https://openalex.org/keywords/cardiovascular-risk","display_name":"cardiovascular risk","score":0.6019999980926514},{"id":"https://openalex.org/keywords/fracture-prevention","display_name":"fracture prevention","score":0.41600000858306885}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.934990406036377},{"id":"https://openalex.org/C2776541429","wikidata":"https://www.wikidata.org/wiki/Q165328","display_name":"Osteoporosis","level":2,"score":0.8411101698875427},{"id":"https://openalex.org/C2777164284","wikidata":"https://www.wikidata.org/wiki/Q277954","display_name":"Estrogen","level":2,"score":0.8076068162918091},{"id":"https://openalex.org/C2780159708","wikidata":"https://www.wikidata.org/wiki/Q17003363","display_name":"Hormone replacement therapy (female-to-male)","level":3,"score":0.5469617247581482},{"id":"https://openalex.org/C133507102","wikidata":"https://www.wikidata.org/wiki/Q4712977","display_name":"Genitourinary system","level":2,"score":0.44696661829948425},{"id":"https://openalex.org/C2779329777","wikidata":"https://www.wikidata.org/wiki/Q2304401","display_name":"Bone density","level":3,"score":0.43223702907562256},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.4312428832054138},{"id":"https://openalex.org/C124490489","wikidata":"https://www.wikidata.org/wiki/Q7936963","display_name":"Vitamin D and neurology","level":2,"score":0.42579129338264465},{"id":"https://openalex.org/C170033053","wikidata":"https://www.wikidata.org/wiki/Q952019","display_name":"Bone remodeling","level":2,"score":0.41054579615592957},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.35970738530158997},{"id":"https://openalex.org/C2779279991","wikidata":"https://www.wikidata.org/wiki/Q6058681","display_name":"Testosterone (patch)","level":2,"score":0.13188928365707397}],"mesh":[{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004305","descriptor_name":"Dose-Response Relationship, Drug","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004359","descriptor_name":"Drug Therapy, Combination","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004967","descriptor_name":"Estrogens","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":false},{"descriptor_ui":"D004967","descriptor_name":"Estrogens","qualifier_ui":"Q000172","qualifier_name":"deficiency","is_major_topic":false},{"descriptor_ui":"D004967","descriptor_name":"Estrogens","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015519","descriptor_name":"Bone Density","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015663","descriptor_name":"Osteoporosis, Postmenopausal","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":false},{"descriptor_ui":"D015663","descriptor_name":"Osteoporosis, Postmenopausal","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D015663","descriptor_name":"Osteoporosis, Postmenopausal","qualifier_ui":"Q000191","qualifier_name":"economics","is_major_topic":false},{"descriptor_ui":"D015663","descriptor_name":"Osteoporosis, Postmenopausal","qualifier_ui":"Q000517","qualifier_name":"prevention & control","is_major_topic":false},{"descriptor_ui":"D015914","descriptor_name":"Estrogen Replacement Therapy","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":true},{"descriptor_ui":"D016723","descriptor_name":"Bone Remodeling","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D016723","descriptor_name":"Bone Remodeling","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D050723","descriptor_name":"Fractures, Bone","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1016/s0889-857x(05)70191-5","doi":"https://doi.org/10.1016/s0889-857x(05)70191-5","is_oa":false,"landing_page_url":"https://doi.org/10.1016/s0889-857x(05)70191-5","pdf_url":null,"source":{"id":"https://openalex.org/S28431432","display_name":"Rheumatic Disease Clinics of North America","issn_l":"0889-857X","issn":["0889-857X","1558-3163"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Rheumatic Disease Clinics of North America","raw_type":"journal-article"},{"id":"pmid:11285992","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/11285992","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Rheumatic diseases clinics of North America","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":1.0,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":165,"referenced_works":["https://openalex.org/W4544687","https://openalex.org/W43901977","https://openalex.org/W71446123","https://openalex.org/W111127352","https://openalex.org/W175660244","https://openalex.org/W1517426366","https://openalex.org/W1552563052","https://openalex.org/W1560499904","https://openalex.org/W1937625525","https://openalex.org/W1964802431","https://openalex.org/W1965948482","https://openalex.org/W1966445103","https://openalex.org/W1968112125","https://openalex.org/W1968774230","https://openalex.org/W1969239561","https://openalex.org/W1969336465","https://openalex.org/W1970182232","https://openalex.org/W1971290372","https://openalex.org/W1972488771","https://openalex.org/W1973411875","https://openalex.org/W1976426926","https://openalex.org/W1976930486","https://openalex.org/W1978675042","https://openalex.org/W1980786945","https://openalex.org/W1983478108","https://openalex.org/W1983608420","https://openalex.org/W1985953874","https://openalex.org/W1985983090","https://openalex.org/W1991099779","https://openalex.org/W1992407302","https://openalex.org/W1993733992","https://openalex.org/W1994271230","https://openalex.org/W1996025707","https://openalex.org/W1997953668","https://openalex.org/W1998818726","https://openalex.org/W1999466669","https://openalex.org/W2001987600","https://openalex.org/W2002535656","https://openalex.org/W2003803144","https://openalex.org/W2004236425","https://openalex.org/W2004302812","https://openalex.org/W2005320246","https://openalex.org/W2008295672","https://openalex.org/W2008332482","https://openalex.org/W2008491340","https://openalex.org/W2008492445","https://openalex.org/W2011702879","https://openalex.org/W2013449642","https://openalex.org/W2016674232","https://openalex.org/W2018464245","https://openalex.org/W2019174938","https://openalex.org/W2020111132","https://openalex.org/W2021972583","https://openalex.org/W2022852065","https://openalex.org/W2023268781","https://openalex.org/W2023445148","https://openalex.org/W2023639601","https://openalex.org/W2027396351","https://openalex.org/W2028611611","https://openalex.org/W2028655493","https://openalex.org/W2029307104","https://openalex.org/W2031570803","https://openalex.org/W2033133946","https://openalex.org/W2035593552","https://openalex.org/W2036473720","https://openalex.org/W2043231457","https://openalex.org/W2044266185","https://openalex.org/W2046917334","https://openalex.org/W2046983302","https://openalex.org/W2055564809","https://openalex.org/W2057880427","https://openalex.org/W2057965610","https://openalex.org/W2058169315","https://openalex.org/W2058356008","https://openalex.org/W2061958057","https://openalex.org/W2065698632","https://openalex.org/W2066702609","https://openalex.org/W2068608478","https://openalex.org/W2069877304","https://openalex.org/W2071071972","https://openalex.org/W2072586683","https://openalex.org/W2074443707","https://openalex.org/W2075786281","https://openalex.org/W2077153720","https://openalex.org/W2079450135","https://openalex.org/W2080480859","https://openalex.org/W2083235997","https://openalex.org/W2089256384","https://openalex.org/W2089559835","https://openalex.org/W2090763861","https://openalex.org/W2094330965","https://openalex.org/W2094928686","https://openalex.org/W2097128357","https://openalex.org/W2097506722","https://openalex.org/W2099648194","https://openalex.org/W2102308673","https://openalex.org/W2104322072","https://openalex.org/W2105584900","https://openalex.org/W2106601653","https://openalex.org/W2107101733","https://openalex.org/W2107410353","https://openalex.org/W2113917022","https://openalex.org/W2115671362","https://openalex.org/W2120025674","https://openalex.org/W2120171164","https://openalex.org/W2121829164","https://openalex.org/W2127242828","https://openalex.org/W2129623136","https://openalex.org/W2134137902","https://openalex.org/W2136478247","https://openalex.org/W2137295068","https://openalex.org/W2138822479","https://openalex.org/W2140086733","https://openalex.org/W2148727186","https://openalex.org/W2148921356","https://openalex.org/W2151375247","https://openalex.org/W2153005915","https://openalex.org/W2159079009","https://openalex.org/W2162822427","https://openalex.org/W2164094541","https://openalex.org/W2167749649","https://openalex.org/W2169069042","https://openalex.org/W2182556426","https://openalex.org/W2201610967","https://openalex.org/W2215064205","https://openalex.org/W2275183869","https://openalex.org/W2285718597","https://openalex.org/W2312911576","https://openalex.org/W2313507666","https://openalex.org/W2314892802","https://openalex.org/W2317628894","https://openalex.org/W2318227030","https://openalex.org/W2321122739","https://openalex.org/W2322274315","https://openalex.org/W2323923429","https://openalex.org/W2337197041","https://openalex.org/W2340559658","https://openalex.org/W2394783378","https://openalex.org/W2395294358","https://openalex.org/W2396961843","https://openalex.org/W2397582790","https://openalex.org/W2398791653","https://openalex.org/W2400043101","https://openalex.org/W2402937525","https://openalex.org/W2411298473","https://openalex.org/W2411544617","https://openalex.org/W2412190968","https://openalex.org/W2413976406","https://openalex.org/W2416574676","https://openalex.org/W2442061983","https://openalex.org/W2461789729","https://openalex.org/W2469416225","https://openalex.org/W2496211095","https://openalex.org/W2734840715","https://openalex.org/W4232432044","https://openalex.org/W4237379088","https://openalex.org/W4240760506","https://openalex.org/W4248218161","https://openalex.org/W4248529325","https://openalex.org/W4253677188","https://openalex.org/W4255513594","https://openalex.org/W4285719527","https://openalex.org/W4293281135","https://openalex.org/W4302866802","https://openalex.org/W6711979444"],"related_works":["https://openalex.org/W2212276952","https://openalex.org/W2419115159","https://openalex.org/W7144793674","https://openalex.org/W3041009444","https://openalex.org/W2018583822","https://openalex.org/W187836565","https://openalex.org/W1979668065","https://openalex.org/W2414543297","https://openalex.org/W2011702879","https://openalex.org/W2466601150"],"abstract_inverted_index":null,"counts_by_year":[{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":1},{"year":2022,"cited_by_count":1},{"year":2020,"cited_by_count":3},{"year":2019,"cited_by_count":1},{"year":2016,"cited_by_count":2},{"year":2015,"cited_by_count":2},{"year":2014,"cited_by_count":2},{"year":2013,"cited_by_count":2},{"year":2012,"cited_by_count":2}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}